Auxiliary Table 1. Case-control and nested case-control studies in E2C2 that collected DNA
Center/ Study name / PrincipalInvestigator / Study
location / # Cases/
cases
with DNA / # Controls/
controls
with DNA / Years of data collection
Yale University –
Genetic and Lifestyle
Interplay / Herbert Yu / CT / 900/900* / 900/900* / 2003-present
University of Turin –
Diet, Body Weight, and
Gene-Environment
Interactions / Carlotta
Sacerdote / Turin / 259/239 / 66/62 / 2000-present
University of Athens / Eleni Petridou/
Nicholas
Dessypris / Athens / 107/23 / 107/23 / 1999, 2007-present
Queensland Institute
for Medical Research –
ANECS / Amanda
Spurdle / Australia / 1,500/
1,350* / 1,500/
1,350* / 2005-2007
University of Hawaii / Marc
Goodman / HI / 168/168 / 329/329 / 2001-2006
Memorial Sloan-
Kettering Cancer
Center - EDGE / Sara Olson / NJ / 469/417 / 467/402 / 2001-2006
Fred Hutchinson
Cancer Research
Center – Molecular
Epidemiology of
Endometrial Cancer / Chu Chen / WA / 881/783 / 1021/798 / 1994-2005
Vanderbilt University -
SECS / Xiao Ou Shu / Shanghai / 1,199/1,130 / 1,212/1,124 / 1997-2003
NCI – Polish
Endometrial Cancer
Study / Montserrat
Garcia-Closas / Warsaw,
Lodz / 551/497 / 1,925/1,024 / 2001-2003
University of
Pennsylvania - WISE / Timothy
Rebbeck / PA/ NJ / 1,000/626 / 2,000/1,583 / 1999-2002
Centre for Research
In Women’s Health / Steven Narod / Canada / 542/542 / 592/592
Total / 7,576/6,675 / 10,119/8,187
Nested case-control
studies
American Cancer
Society – Cancer
Prevention Study II
Nutrition Cohort / Alpa Patel / 21 US
states / 421/ 421 / 842/842 / 1992-present
Karolinksa Institutet -
Swedish Mammography
Cohort / Alicja Wolk / Sweden / 598/360 / 2,000/1,204 / 1997-2005
Johns Hopkins -
CLUE I and II / Kathy
Helzlsouer,
Dana Christo / MD / 195/93 / 195/93 / 1974-2004
USC/NCCC –
NEET (CA Teacher’s
Cohort) / Pamela
Horn-Ross,
Leslie
Bernstein / CA / 650/356 / 686/686 / 1995-2004
Harvard University –
Nurses’ Health Study / Immaculata
De Vivo / 11 US
states / 650/650 / 1,641/1,641 / 1976-2004
Total / 2,514/1,880 / 5,364/4,466
*anticipated numbers; data still being collected
Auxiliary Table 2. Cohort studies in E2C2 that collected DNA
Investigator / Study
location / # Cases/
cases
with DNA / Cohort size / Years of data collection
New York University -
Women’s Health Study / Anne
Zeleniuch-
Jacquotte / NY / 211/ 211 / 14,274 / 1985-present
University of Hawaii,
University of Southern
California –
Multiethnic Cohort / Lawrence
Kolonel, Brian
Henderson / CA, HI / 650/350 / 133,479 / 1993-present
Fred Hutchinson
Cancer Research
Center - VITAL / Emily White / WA / 194/ 134 / 27,411 / 2000-2006
University of Tromso-
CONOR / Anne-Sofie
Furberg / Norway / 800/800 / 90,000 / 1974-2006
Maastricht University – Netherlands Cohort
Study / PA Van den
Brandt / Netherlands / 466/ 370 / 62,573 / 1986-2002
Vanderbilt University
- Shanghai Women’s
Health Study / Wei Zheng / Shanghai / 90/ 75 / 75,000 / 1996-2000
Cancer Care Ontario / Thomas Rohan,
Nancy Kreiger / Canada / 125/ 121 / 39,618 / 1992-1999
National Cancer
Institute, Milan / Vittorio
Krogh / Varese / 53/53 / 10,787 / 1987-1992
Total / 2,589/2,114 / 453,142
Auxiliary Table 3. Case-control studies in E2C2 that did not collect DNA
Investigator / Study
location / # Cases / # Controls / Years of data collection
Northern California
Cancer Center –
Phytoestrogens, Physical
Activity, and
Endometrial Cancer / Pamela
Horn-Ross / CA / 500 / 470 / 1996-2001
Fred Hutchinson
Cancer Research
Center / Chu Chen / WA / 1,304 / 1,779 / 1985-1999
Roswell Park Cancer
Institute - PEDS / Susan
McCann / NY / 541 / 541 / 1982-1998
Fred Hutchinson Cancer
Research Center –
Postmenopausal
Hormones and Risk of
Endometrial Cancer / Polly
Newcomb / WI / 745 / 2,408 / 1992-1994
University of Hawaii / Marc
Goodman / HI / 322 / 511 / 1985-1993
Roswell Park Cancer
Institute – Western NY
Diet Study / Susan
McCann / NY / 232 / 639 / 1986-1991
Karolinska Institutet / Elisabete
Weiderpass / Sweden / 789 / 3,386 / 1993-1995
Total / 4,433 / 9,734
Auxiliary Table 4. Cohort studies in E2C2 that did not collect DNA
Investigator / Study
location / # Cases / Cohort size / Years of data collection
NIH – AARP Diet
and Health Study / James Lacey / 8 US states / 1,200 / 103,000 / 1995-present
University of
Minnesota -
Iowa Women’s Health
Study / Aaron Folsom/
Kristin
Anderson / IA / 664 / 27,018 / 1986-2005
Albert Einstein College
Of Medicine – Canadian National Breast
Screening Study / Thomas Rohan / Canada / 500 / 89,835 / 1980-2000
University of Tromso-
Energy Balance and
Cancer / Anne-Sofie
Furberg / Norway / 300 / 40,000 / 1974-2006
NCI – BCDDP
Follow-up Study / James Lacey,
Catherine
Schairer / 27 US cities / 565 / 61,430 / 1979-1998
Total / 3,229 / 321,283