Audit data of X-PERT demonstrates a 23% improvement in patient empowerment, and after
12 months a 6mmol/mol reduction in HbA1c, 4.4kg reduction in weight and 2.4cm lower
waist circumference, plus reductions in BP and cholesterol. This is in contrast to UKPDS
data that shows continued weight gain without intervention. Over the first 6 months, X-PERT
has been shown to generate an 8.3% reduction in prescribing costs equating to average
savings in prescribing costs at £131,052 per 1,000 people attending, per year.
Below are links to X-PERT’s key publications on their programme:
• Deakin et al 2006-Diabetic Medicine
• X-PERT Audit Award Report 2016
Evidence clearly demonstrates the positive impact of sustained behaviour change support:
• People engaged on lifestyle intervention support lost 8.6% of body weight1.
• A systematic review in the BMJ identified that those with behavioural interventions
centred on physical activity and diet achieved an incremental 1.56% sustained loss in
body weight2.
• Another systematic review and meta analysis published by Diabetes Care found that
usingbehavioural interventions increased physical activity generating improved
HbA1c and BMI3.
• Professor Roy Taylor has published that individuals have their own Personal Fat
Threshold, noting that ⅓ of those in UKPDS who developed Type 2 had a BMI below
25, but outcomes improved for all with weight loss4.
• A systematic review of interventions to increase physical activity and improve HbA1c
identified five specific behaviour change techniques that addressed both5. We are the
only solution to incorporate all in our approach.
• An HTA study for NIHR published in the Lancet in July 2016 found that with ongoing
web and remote support on diet, obese patients achieved 50% greater weight loss
than the control group who just had access to the web guidance. That loss was
sustained by 30% of people compared to 21% in the control group.
In addition, there is strong evidence that behavioural interventions increased levels of
physical activity, generating further improvement in HbA1c and weight loss.
1 Redmon, JB et al (Look AHEAD Research Group) 2010 Effect of the Look AHEAD Study Intervention on
Medication Use and Related Cost to Treat Cardioascular Disease Risk Factors in Individuals with Type 2
Diabetes Diabetes Care, 33:1153-1158
2 Dombrowski, SU et al 2014 Long term maintenance of weight loss with non-surgical interventions in
obese adults: systematic review and meta-analyses of randomised controlled trials BMJ 348, g2646
3 Avery et al 2012 Changing Physical Activity Behavior in Type 2 Diabetes: A Systematic Review and
Meta-Analysis of Behavioral Interventions Diabetes Care, 35:2681-2689
4 Taylor R et al 2016 Very Low Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes:
Pathophysiological Changes in Responders and Nonresponders Diabetes Care, 39(5): 808-815
5 Avery et al 2015 Successful behavioural strategies to increase physical activity and improve glucose
control in adults with Type 2 diabetes Diabetic Medicine, 32:1058-1062