Appendix 1. Search Terms, Strategy and Results in Medline Database

Appendix 1. Search terms, strategy and results in Medline database.

# / Searches / Results
1 / exp Anesthetics, Inhalation/ / 44982 / Volatile or Inhalation Anesthetics & Related Terms Component
2 / Anesthetics, Inhalation.rw. / 11062
3 / (inhal* adj2 an?esth*).mp. / 26719
4 / VIMA.tw. [volatile induction/maintenance anaesthesia ] / 36
5 / (inhal* adj2 agent?).tw. / 1297
6 / (inhal* adj3 neuroan?esth*).mp. / 5
7 / (inhal* adj3 neuro-an?esth*).mp. / 1
8 / (volatile adj2 an?esth*).mp. / 3761
9 / (volatile adj2 neuroan?esth*).mp. / 2
10 / (volatile adj2 neuro-an?esth*).mp. / 0
11 / Enflurane?.mp. / 3577
12 / Ethyl Ether?.mp. / 3611
13 / Halothane?.mp. / 19239
14 / Isoflurane?.mp. / 11913
15 / Methoxyflurane?.mp. / 2287
16 / Nitrous Oxide?.mp. / 17315
17 / Trichloroethylene?.mp. / 4582
18 / Xenon?.mp. / 9491
19 / desflurane?.mp. / 1737
20 / sevoflurane?.mp. / 6140
21 / or/1-20 [Inhalation Anesthetics & Related Terms] / 73812
22 / exp Anesthetics, Intravenous/ / 66616 / Intravenous Anesthetics & Related Terms Component
23 / Anesthetics, Intravenous.rw. / 9950
24 / (intraven* adj2 an?esth*).mp. / 21025
25 / TIVA.tw. [total intravenous anaesthesia] / 503
26 / (intravenous adj2 agent?).tw. / 1538
27 / (intraven* adj3 neuroan?esth*).mp. / 1
28 / (intraven* adj3 neuro-an?esth*).mp. / 1
29 / Alfentanil?.mp. / 2230
30 / Chloralose?.mp. / 5671
31 / Diazepam?.mp. / 23429
32 / Etomidate?.mp. / 2231
33 / Fentanyl?.mp. / 16955
34 / Methohexital?.mp. / 1709
35 / Midazolam?.mp. / 10599
36 / Propanidid?.mp. / 991
37 / Propofol?.mp. / 15324
38 / Sodium Oxybate?.mp. / 1559
39 / Sufentanil?.mp. / 2192
40 / Thiamylal?.mp. / 694
41 / Thiopental?.mp. / 7929
42 / Urethane?.mp. / 12005
43 / lorazepam?.mp. / 3797
44 / meperidine?.mp. / 6151
45 / remifentanil?.mp. / 3069
46 / ketamine?.mp. / 13446
47 / droperidol?.mp. / 2674
48 / or/22-47 [Intravenous Anesthetics & Related Terms] / 112617
49 / 21 and 48 [Inhaltion Anesthetics + Intravenous Anesthetics] / 14277
50 / exp Craniotomy/ / 10045 / Craniotomy & Related Terms Component
51 / craniotom*.mp. / 14716
52 / (intracranial* adj2 surger*).mp. / 1087
53 / (intra-cranial* adj2 surger*).mp. / 5
54 / (intracranial* adj2 surgical*).mp. / 247
55 / (intra-cranial* adj2 surgical*).mp. / 1
56 / (intracranial* adj2 operation*).mp. / 271
57 / (intra-cranial* adj2 operation*).mp. / 3
58 / exp Supratentorial Neoplasms/ / 23672
59 / (SUPRATENTORIAL adj4 surg*).tw. / 270
60 / (SUPRATENTORIAL adj4 resect*).tw. / 116
61 / (SUPRATENTORIAL adj4 operat*).tw. / 89
62 / (SUPRATENTORIAL adj2 lesion?).tw. / 405 / Craniotomy & Related Terms Component
63 / (SUPRATENTORIAL adj2 cancer*).tw. / 0
64 / (SUPRATENTORIAL adj2 neoplas*).tw. / 35
65 / Trephining/ / 1160
66 / Trephin???.tw. / 2348
67 / burr hole?.tw. / 1136
68 / exp Skull/su / 41680
69 / (skull?? adj2 surg*).tw. / 1033
70 / exp Neurosurgical Procedures/ / 146518
71 / Neurosurgery/ / 12465
72 / neurosurgeon?.tw. / 5563
73 / (brain? adj2 (surger* or surgic*)).mp. / 2686
74 / (brain? adj2 operation?).mp. / 341
75 / (brain? adj2 resect*).mp. / 660
76 / neurosurg*.tw. / 29790
77 / or/50-76 [Craniotomy & related very broad terms] / 240064
78 / 49 and 77 [(Inhaltion Anesthetics + Intravenous Anesthetics) + Craniotomy] / 750
Limits applied:
79 / remove duplicates from 78 / 718
80 / limit 79 to english language / 572
81 / animals/ not (animals/ and humans/) / 3966240
82 / 80 not 81 / 472
83 / limit 80 to human / 463
84 / 82 or 83 / 472
85 / 201211*.ed. / 69590
86 / 201212*.ed. / 63956
87 / 2013*.ed. / 709022
88 / "2013".yr. / 346952
89 / or/85-88 / 842568
90 / 84 and 89 ➔ update search results for Nov-Dec 2012 and all 2013 ➔ / 11

Appendix 2. Search terms, strategy and results in Embase database.

Embase Classic+Embase 1947 to 2013 November 08
# / Searches / Results / Search Type
1 / exp inhalation anesthetic agent/ / 133109 / Advanced
2 / inhalation anesthesia/ / 13199 / Advanced
3 / anesthetic agent/ih [Inhalational Drug Administration] / 961 / Advanced
4 / (inhal* adj2 an?esth*).mp. / 29264 / Advanced
5 / VIMA.tw. [volatile induction/maintenance anaesthesia ] / 54 / Advanced
6 / (inhal* adj2 agent?).tw. / 1962 / Advanced
7 / (inhal* adj3 neuroan?esth*).mp. / 5 / Advanced
8 / (inhal* adj3 neuro-an?esth*).mp. / 1 / Advanced
9 / (volatile adj2 an?esth*).mp. / 6293 / Advanced
10 / (volatile adj2 neuroan?esth*).mp. / 3 / Advanced
11 / (volatile adj2 neuro-an?esth*).mp. / 0 / Advanced
12 / Enflurane?.mp. / 8477 / Advanced
13 / Ethyl Ether?.mp. / 1446 / Advanced
14 / Halothane?.mp. / 35635 / Advanced
15 / Isoflurane?.mp. / 22060 / Advanced
16 / Methoxyflurane?.mp. / 5231 / Advanced
17 / Nitrous Oxide?.mp. / 39103 / Advanced
18 / Trichloroethylene?.mp. / 12085 / Advanced
19 / Xenon?.mp. / 16211 / Advanced
20 / desflurane?.mp. / 4326 / Advanced
21 / sevoflurane?.mp. / 14253 / Advanced
22 / or/1-21 / 166963 / Advanced
23 / exp intravenous anesthesia/ / 9414 / Advanced
24 / intravenous anesthetic agent/ / 3222 / Advanced
25 / anesthetic agent/iv [Intravenous Drug Administration] / 1308 / Advanced
26 / (intraven* adj2 an?esth*).mp. / 30179 / Advanced
27 / TIVA.tw. [total intravenous anaesthesia] / 947 / Advanced
28 / (intravenous adj2 agent?).tw. / 2226 / Advanced
29 / (intraven* adj3 neuroan?esth*).mp. / 6 / Advanced
30 / (intraven* adj3 neuro-an?esth*).mp. / 1 / Advanced
31 / Alfentanil?.mp. / 6300 / Advanced
32 / Chloralose?.mp. / 8734 / Advanced
33 / Diazepam?.mp. / 70867 / Advanced
34 / Etomidate?.mp. / 6496 / Advanced
35 / Fentanyl?.mp. / 49917 / Advanced
36 / Methohexital?.mp. / 4376 / Advanced
37 / Midazolam?.mp. / 33851 / Advanced
38 / Propanidid?.mp. / 2388 / Advanced
39 / Propofol?.mp. / 36813 / Advanced
40 / Sodium Oxybate?.mp. / 326 / Advanced
41 / Sufentanil?.mp. / 7188 / Advanced
42 / Thiamylal?.mp. / 1818 / Advanced
43 / Thiopental?.mp. / 27421 / Advanced
44 / Urethane?.mp. / 12809 / Advanced
45 / lorazepam?.mp. / 20865 / Advanced
46 / meperidine?.mp. / 3833 / Advanced
47 / remifentanil?.mp. / 8148 / Advanced
48 / ketamine?.mp. / 29283 / Advanced
49 / droperidol?.mp. / 10223 / Advanced
50 / or/23-49 / 244535 / Advanced
51 / 22 and 50 / 42631 / Advanced
52 / exp Craniotomy/ / 19856 / Advanced
53 / craniotom*.mp. / 23709 / Advanced
54 / (intracranial* adj2 surger*).mp. / 3058 / Advanced
55 / (intra-cranial* adj2 surger*).mp. / 12 / Advanced
56 / (intracranial* adj2 surgical*).mp. / 3106 / Advanced
57 / (intra-cranial* adj2 surgical*).mp. / 2 / Advanced
58 / (intracranial* adj2 operation*).mp. / 608 / Advanced
59 / (intra-cranial* adj2 operation*).mp. / 8 / Advanced
60 / exp Supratentorial Neoplasms/ / 140659 / Advanced
61 / (SUPRATENTORIAL adj4 surg*).tw. / 416 / Advanced
62 / (SUPRATENTORIAL adj4 resect*).tw. / 180 / Advanced
63 / (SUPRATENTORIAL adj4 operat*).tw. / 130 / Advanced
64 / (SUPRATENTORIAL adj2 lesion?).tw. / 650 / Advanced
65 / (SUPRATENTORIAL adj2 cancer*).tw. / 2 / Advanced
66 / (SUPRATENTORIAL adj2 neoplas*).tw. / 54 / Advanced
67 / Trephining/ / 4011 / Advanced
68 / Trephin???.tw. / 3765 / Advanced
69 / burr hole?.tw. / 1765 / Advanced
70 / exp Skull/su / 19918 / Advanced
71 / (skull?? adj2 surg*).tw. / 1518 / Advanced
72 / (cranial adj2 surg*).tw. / 928 / Advanced
73 / exp neurosurgery/ / 223119 / Advanced
74 / (brain? adj2 (surger* or surgic*)).mp. / 17071 / Advanced
75 / (brain? adj2 operation?).tw. / 592 / Advanced
76 / (brain? adj2 resect*).tw. / 995 / Advanced
77 / neurosurgeon/ / 1108 / Advanced
78 / neurosurgeon?.tw. / 8717 / Advanced
79 / neurosurg*.tw. / 47856 / Advanced
80 / or/52-79 / 396405 / Advanced
81 / 51 and 80 / 2087 / Advanced
82 / (exp animals/ or exp animal experimentation/ or nonhuman/) not ((exp animals/ or exp animal experimentation/ or nonhuman/) and exp human/) / 5932029 / Advanced
83 / 81 not 82 / 1922 / Advanced
84 / limit 81 to human / 1636 / Advanced
85 / 83 or 84 / 1922 / Advanced
86 / limit 85 to english language / 1570 / Advanced
87 / limit 86 to embase / 1486 / Advanced
88 / remove duplicates from 87 / 1484 / Advanced
89 / limit 88 to (book or book series or conference abstract or "conference review" or conference proceeding) / 107 / Advanced
90 / 88 not 89 / 1377 / Advanced
91 / 201211*.dd. / 98109 / Advanced
92 / 201212*.dd. / 83322 / Advanced
93 / 2013*.dd. / 1183137 / Advanced
94 / 201245*.em. / 19846 / Advanced
95 / 201246*.em. / 23180 / Advanced
96 / 201247*.em. / 15779 / Advanced
97 / 201248*.em. / 26580 / Advanced
98 / 201249*.em. / 25034 / Advanced
99 / 201250*.em. / 18209 / Advanced
100 / 201251*.em. / 20402 / Advanced
101 / 201252*.em. / 18277 / Advanced
102 / 2013*.em. / 1383482 / Advanced
103 / or/91-102 / 1550789 / Advanced
104 / 90 and 103 / 63 / Advanced