Anne Klibanski, M.D.

1/30/02

CURRICULUM VITAE

Name: Anne Klibanski, M.D.

Place of Birth: New York City, New York

Education:

1971 B.A. Barnard College, New York City, NY

1975 M.D. New York University School of Medicine, New York City, NY

1998 M.A. Harvard University (Honorary)

Postdoctoral Training:

Internship and Residencies:

1975-1976 Intern in Medicine, Bellevue Hospital, New York City, NY

1976-1977 Resident in Medicine, Bellevue Hospital, New York City, NY

1977-1978 Senior Resident in Medicine, Bellevue Hospital, New York City, NY

Licensure and Certification:

1978 Massachusetts Board of Registration

1978 American Board of Internal Medicine

1981 Endocrinology and Metabolism

Academic Appointments:

1978-1980 Research Fellow in Medicine, Harvard Medical School

1980-1983 Instructor in Medicine, Harvard Medical School

1983-1989 Assistant Professor of Medicine, Harvard Medical School

1989-1997 Associate Professor of Medicine, Harvard Medical School

1997-present Professor of Medicine, Harvard Medical School

Hospital Appointments:

1978-1980 Clinical and Research Fellow in Reproductive Medicine, Massachusetts General Hospital

1980-1981 Clinical and Research Fellow, Department of Medicine,

Massachusetts General Hospital

1981-1983 Clinical Assistant in Medicine, Massachusetts General Hospital

1983-1986 Assistant in Medicine, Massachusetts General Hospital

1987-1990 Assistant Physician in Medicine, Massachusetts General Hospital

1990-1997 Associate Physician in Medicine, Massachusetts General Hospital

1997-present Physician, Massachusetts General Hospital

1998-present Physician to the Affiliate Staff, Brigham and Women’s Hospital

1998-present Affiliated Faculty, Harvard/Massachusetts Institute of Technology Division of Health Science and Technology

Principal Clinical and Hospital Service Responsibilities:

1981-present Attending Physician, Medical Services, Massachusetts General Hospital

1983-1990 Attending Physician, Thyroid Clinic, Massachusetts General Hospital

1983-present Attending Physician, Endocrine Unit, Massachusetts General Hospital

1985-present Attending Physician, Neuroendocrine Clinical Center, Massachusetts General Hospital

1985-present Director, Neuroendocrine Clinical Center, Massachusetts General Hospital

1986-1990 Associate Director, Mallinckrodt Clinical Research Center, Massachusetts General Hospital

1989-present Chief, Neuroendocrine Unit, Massachusetts General Hospital

1989-present Co-Director, Mallinckrodt Clinical Research Center, Massachusetts General Hospital

1993-1996 Co-Director, Thyroid-Endocrine Clinical Laboratory, Massachusetts General Hospital

1995-1998 Head, Division of Endocrinology, Massachusetts General Hospital

Awards and Honors:

1971 B.A., magna cum laude with honors in literature

1971 Michael T. Glynne Memorial Prize for academic excellence

1975 Alpha Omega Alpha

1975 New York University Medical School Alumnae Award

1975 American Women's Medical Association Citation

1981 Recipient NRSA - National Institutes of Health

1983 Clinical Associate Physician Award - National Institutes of Health

1997 Honorary Master’s Degree, Harvard University

1998 Harvard Medical School Dean’s Award for Advancement of Women Faculty

Major Hospital and University Committee Assignments:

1986-1998 Scientific Advisory Committee, Massachusetts General Hospital

1987 Committee on Clinical Research, Massachusetts General Hospital

1989-present Program Committee, Endocrine Fellowship Program

1991-present Committee on Women

1992-present Committee on Research

1993-1994 MGH Clinical Research Taskforce

1994-present Trustees' Committee on Women in Science

1994-1995 Clinical Research Training Committee

1995-1996 Clinical Research Support Office Committee

1996-1999 Partners’ Senior Advisory Committee on Women in Academic Medicine

1996-present Department of Medicine Promotions Committee, Massachusetts General Hospital

1997-2000 Operations Improvement Leadership Committee, Massachusetts General Hospital

1997-present Review Committee for the Massachusetts General Hospital, Claflin Distinguished Scholar Awards

1997-present Academic Council, Department of Medicine

1998-present Chair, Faculty Development Committee, Department of Medicine

1998 Harvard Medical School ad hoc Promotion Committee, Candidate Evaluation

1998-2000 Harvard Medical School 50th Anniversary Program for Scholars in Medicine Selection Committee

1998-2001 Harvard Medical School Faculty Fellowship Committee in the Faculty of Medicine

1999-2000 Harvard Medical School, Clinician Teacher, Longer Service Promotion Subcommittee

1999-present Women’s Health Executive Committee, Massachusetts General Hospital

1999-present Clinical Research Council of Massachusetts General Hospital

2000-2001  Chairperson, Partners Committee on Scientific Misconduct

2000-present Department of Medicine, Internship Selection Committee, Massachusetts General Hospital

2000-present Mentor, Biometrix Harvard-MIT Undergraduate Mentoring Program

2001 Harvard Medical School, Executive Planning Committee,

Nutrition and Women’s Health Symposium

2001-present Scientific Management Committee for the MGH NMR Center

Memberships in Professional Societies:

1975 Alpha Omega Alpha

1982 Endocrine Society

1984 Federation for Clinical Research

1989 American Society of Bone and Mineral Research

1991 American Society for Clinical Investigation

1998 Association of American Physicians

1999 Association for Patient-Oriented Research

1999 The Growth Hormone Research Society

Editorial Boards and Editorships:

1989-1992 Journal of Clinical Endocrinology and Metabolism

1996-present Neuroendocrine Editor, The Endocrinologist

1998-2001 Journal of Clinical Endocrinology and Metabolism

2001-present Harvard Women's Health Watch

2002 Editor, Clinics in Endocrinology and Metabolism Series, Volume Neuroendocrinology, Saunders, Philadelphia, PA

NIH Study Sections and Grant Review Committees:

1990-1992 Reproductive Endocrinology Study Section - ad hoc Reviewer

1992-1996 Member, Endocrinology Research Program and Advisory Committee

1992-1996 Member, Review Committee, National Hormone and Pituitary Program

1992-present National Osteoporosis Foundation ad hoc Reviewer

1993-1997 Member, NIH Study Section B, NIDDK

1997-present NIH, NIDDK ad hoc Reviewer

1997 Chair, ad hoc NIH Review Committee

2000 NIH, OSD/DIRP/NIMH ad hoc Reviewer

Research Interests:

1. Pathogenesis of hypogonadal osteoporosis.

2. The neuroendocrine control of pituitary glycoprotein hormones and their subunits in pituitary adenomas.

3. Pathogenesis of human pituitary tumors.

National Committees/Leadership Roles:

1992-1995 General Clinical Research Center (GCRC) Program Directors' Executive Committee

1992-1993 Chairman, Program Committee, 1992 GCRC Program Directors' National Meeting

1991-1994 Endocrine Society - Women in Endocrinology Executive Committee

1992-1994 Endocrine Society - Women in Endocrinology Nominating Committee

1992-1995 Endocrine Society Postgraduate Education Steering Committee

1994-1996 President Elect, General Clinical Research Center Program Directors' Association

1994-present Advisory Board, Pituitary Tumor Network Association

1995-1996 Co-Chair, International Pituitary Symposium – 1996 meeting

1993-present Board of Directors, The Pituitary Society

1995-1997 Nominating Committee, Endocrine Society

1995-present Scientific Advisory Board, National Osteoporosis Foundation

1996-present Grant Review Committee, National Osteoporosis Foundation

1996-1997 President, General Clinical Research Center National Program Directors’ Association

1997- 1999 Council, National Association of Program Directors in Endocrinology

1997-1998 Member, Women in Endocrinology, Awards Committee

1998 Member, Nominations Committee, National Association of Program Directors in Endocrinology

1998-1999 Chairperson, Women in Endocrinology Awards Committee

1998-1999 Scientific Program Committee, 1999 International Pituitary Symposium

1999 Chairperson, Growth Hormone and Growth Factors in

Endocrinology and Metabolism

1999-present Chairperson, NIH Consensus Development Conference on Osteoporosis

1999 Member, National Bone Health Campaign’s Scientific Task Force

1999-2002 Council, Endocrine Society

2000-2001 Scientific Program Committee, 2001 International Pituitary Congress

Self Report of Teaching:

Local Contributions:

Massachusetts General Hospital/Brigham and Women’s Hospital

1979 Lecturer, Gynecology Postgraduate Course, Massachusetts General Hospital

1980-1990 Lecturer, Reproductive Endocrinology Postgraduate Course, Massachusetts General Hospital

1981-present Lecturer, Endocrinology Postgraduate Course, Massachusetts

General Hospital

1981-present Attending Physician, Medical Services, Massachusetts General Hospital

1981 Lecturer, MGH Research Symposium

1982-1984 Lecturer, Surgery Postgraduate Course, Massachusetts General Hospital

1982-1984 Lecturer, Thyroid Postgraduate Course Massachusetts General Hospital

1983-1984 Lecturer, Brigham and Women's Hospital, Gynecology Rounds

1983-present Lecturer, Neurosurgery Grand Rounds, Massachusetts General Hospital

1983-present Endocrinology Training Program, Attending - Endocrine Service

1984-1990  Lecturer, Reproductive Endocrinology Rounds, Massachusetts General Hospital

1985-1990  Thyroid Clinic Attending

1985-present Neuroendocrine Clinical Center, Attending Massachusetts General Hospital

1987 Lecturer, Osteoporosis Postgraduate Course, Massachusetts General Hospital

1988-1990 Lecturer, Neurology Postgraduate Course, Massachusetts General Hospital

1988-1990 Lecturer, Women's Health Postgraduate Course, Massachusetts General Hospital

1989 Lecturer, Reproductive Endocrinology and Infertility Course, Brigham and Women's Hospital

1990 Lecturer, Neurosurgery Postgraduate Course, Massachusetts General Hospital

1991-1996 Lecturer, Internal Medicine Course, Massachusetts General Hospital

1992-1993 Preceptor, Division of Medical Ethics, Harvard Medical School

1993 Lecturer, Obstetrics and Gynecology Grand Rounds, Massachusetts General Hospital

1996-present Lecturer, Endocrine Grand Rounds, Massachusetts General Hospital

Local Leadership Roles in Teaching:

1979-1980 Director, Reproductive Endocrine Clinic and Conference, Massachusetts General Hospital

1986-1991 Conference Director and Lecturer, Neuroendocrine Lecture Series, Massachusetts General Hospital

1989-present Executive Committee, Endocrinology and Metabolism Training Program, Massachusetts General Hospital

1989-present Course Director, Endocrinology Postgraduate Course, Massachusetts General Hospital and Harvard Medical School

1998-present Course Director, Faculty Development Seminar Series, Massachusetts General Hospital

Regional, National and International Contributions:

Invited Presentations:

1986 Speaker, Endocrine Grand Rounds, Johns Hopkins Medical Center, Baltimore, MD

1986 Speaker, Medical Grand Rounds, Sinai Hospital, Baltimore, MD

1986 Speaker, Gynecology Grand Rounds, Brigham and Women's Hospital, Boston, MA

1986 Speaker, Endocrine Grand Rounds, National Institutes of Health, Bethesda, MD

1987 Speaker, Symposium on Prolactin-Related Disorders, Key Biscayne, FL

1987 Speaker, Endocrine Grand Rounds, Beth Israel Hospital, Boston, MA

1987 Speaker, Endocrine Grand Rounds, Columbia Presbyterian Medical Center, New York, NY

1987 Speaker, Endocrine Grand Rounds, Brown University Medical Center, Providence, RI

1987 Speaker, Gynecology Grand Rounds, New York Medical College, New York, NY

1987 Speaker, Endocrine Grand Rounds, Massachusetts General Hospital, Boston, MA

1987 Speaker, Symposium on Pituitary Disorders, Postgraduate Assembly, Aspen, CO

1987 Speaker, Endocrine Grand Rounds, Maine Medical Center, Portland, ME

1987 Speaker, Endocrine Grand Rounds, Beth Israel Hospital, Boston, MA

1987 Speaker, Gynecology Grand Rounds, Brigham and Women's Hospital, Boston, MA

1988 Speaker, United Nations Population Council, Rockefeller

University, New York, NY

1988 Speaker, Endocrine Grand Rounds, Brigham and Women's Hospital, Boston, MA

1988 Speaker, Endocrine and Medical Grand Rounds, Dartmouth Medical Center, Hanover, NH

1988 Speaker, Gynecology Grand Rounds, Brigham and Women's Hospital, Boston, MA

1988 Speaker, Pharmacology Rounds, Robert Wood Johnson Medical

Center, New Brunswick, NJ

1988 Speaker, Endocrine Grand Rounds, Columbia University

Center, Columbia - St. Luke's Hospital, New York City, NY
1989 Speaker, Medical Grand Rounds, Southside Hospital,

Stonybrook Medical Center, Bayshore, NY

1989 Speaker, Endocrine Grand Rounds, Tufts-New England Medical

Center, Boston, MA

1989 Speaker, Medical Grand Rounds, George Washington University Medical Center, Washington, DC

1989 Speaker, Endocrine Grand Rounds, Johns Hopkins Medical Center, Baltimore, MD

1990 Speaker, Gynecology Grand Rounds, Malden Hospital, Malden, MA

1990 Speaker, Philadelphia Endocrine Society, Philadelphia, PA

1990 Speaker, Endocrine Grand Rounds, St. Elizabeth's Hospital, Tufts-New England Medical School

1990 Speaker, American Fertility Society, Postgraduate Assembly Washington, DC

1990 Speaker, Endocrine Society Postgraduate Assembly, Honolulu, HI

1991 Visiting Professorship, Brown University, Providence, RI

1991 Speaker, Endocrine Grand Rounds, Brigham & Women's Hospital, Boston, MA

1992 Speaker, National Osteoporosis Foundation New York, NY

1992 Visiting Professorship, University of Massachusetts Medical Center, Worcester, MA

1992 Speaker, Endocrine Grand Rounds, Beth Israel Hospital, Boston, MA

1993 Speaker, Endocrine Grand Rounds, University of Colorado Health Science Center, Denver, CO

1993 Speaker, Colorado Endocrine Society, Denver, CO

1993 Speaker, Endocrine Grand Rounds, Case University Medical Center, Cleveland, OH

1993 Speaker, Florida Endocrine Society, Naples, FL

1993 Speaker, Obstetrics and Gynecology Grand Rounds, Yale University Medical Center, New Haven, CT

1993 Speaker, Endocrine Grand Rounds, University of Virginia, Charlottesville, VA

1994 Speaker, American Diabetes Association Meeting, Boston, MA

1994 Speaker, Third International Symposium on Osteoporosis, Washington, DC

1994 Speaker, Endocrine Grand Rounds, Columbia University Medical Center, New York, NY

1994 Speaker, Clinical Research Grand Rounds, New York University Medical Center, New York, NY

1994 Speaker, International Symposium on Growth Control in Central Nervous System Tumors, Boston, MA

1995 Speaker, Endocrine Grand Rounds, Beth Israel Hospital, Boston, MA

1996 Speaker, Symposium on IGF-I and Osteoporosis, Genentech, San Francisco, CA

1996 Speaker, Endocrine Grand Rounds, University of Minnesota Medical Center, Minneapolis, MN

1996 Speaker, Endocrine Consultants Meeting, Mt. Sinai Medical Center, New York, NY

1996 Speaker, Endocrine Grand Rounds, Case Western Reserve Medical Center, Cleveland, OH

1997 Speaker, Endocrine Grand Rounds, Cornell University Medical Center, New York, NY

1997 Speaker, Medical Grand Rounds, Beth Israel Hospital, Boston, MA

1997 Speaker, Medical Grand Rounds, University of Rochester School of Medicine, Rochester, NY

1997 Speaker, Obstetrics and Gynecology Grand Rounds, Mt. Auburn Hospital, Boston, MA

1997 Speaker, International Symposium on Anabolic Agents in Bone, Alba, Italy

1997 Speaker, Obstetrics and Gynecology Grand Rounds, Tufts New England Medical Center, Boston, MA

1997 Speaker, Obstetrics and Gynecology Grand Rounds, Rutgers New Jersey Medical Center, Newark, NJ

1998 Speaker, Endocrine Grand Rounds, Johns Hopkins University Medical Center, Baltimore, MD

1998 Speaker Endocrine Grand Rounds, Brigham and Women’s Hospital and Children’s Hospital, Boston, MA

1998 Symposium Speaker, American Association of Clinical Endocrinologists, Orlando, FL

1998 Speaker, Medical Grand Rounds, Dartmouth Medical School, Hanover, NH

1998 Speaker, Endocrinology Grand Rounds, Dartmouth Medical

School, Hanover, NH

1998 Speaker, Growth Hormone Symposium, University of Indianapolis, IN

1998 Lecturer, Endocrine Society Clinical Endocrinology Update, Boston, MA

1998 Speaker, Endocrine Conference, Mayo Clinic, Rochester, MN 1998 Speaker, Endocrine Grand Rounds, University of Minnesota, Minneapolis, MN

1998 Speaker, Bone Biology Research Seminar, Detroit Medical Center, Detroit, MI

1999 Speaker, Faulkner Hospital/Brigham and Women’s Hospital, Medical Grand Rounds, Boston, MA

1999 Moderator, GH/IGF-I Scientific Meeting, Pasadena, CA

1999 Speaker, Endocrine Rounds, Beth Israel-Deaconess Medical Center, Boston, MA

1999 Speaker, Endocrine Grand Rounds, Tufts-New England Medical Center, Boston, MA

1999 Speaker, Endocrine Grand Rounds, University of Michigan Medical Center, Ann Arbor, MI

1999 Speaker, Endocrine Grand Rounds, Henry Ford Hospital, Case Western University, Detroit, MI

1999 Speaker, Seminar Speaker on Growth Hormone, Medical College of Ohio, Toledo, OH

2000 Speaker, Endocrine Grand Rounds, University of Connecticut Medical Center, CT

2000 Speaker, Endocrine Grand Rounds, Northwestern University Medical School, Chicago, IL

2000 Speaker, Endocrine Grand Rounds, Beth Israel-Deaconess Medical Center, Boston, MA

2000 Speaker, “Novel Applications of Long-Acting Octreotide”, Endocrine Society Symposium, Toronto, Canada

2000  Speaker, Endocrine Grand Rounds, Henry Ford Hospital, Case Western University, Detroit, MI

2000 Speaker, Endocrine Grand Rounds, University of Massachusetts, Worcester, MA

2000 Visiting Professorship, University of California at San Francisco Medical Center, San Francisco, CA

2000 Speaker, Endocrine Grand Rounds, Brown University, Rhode Island Hospital Medical Center, Providence, RI

2000 Speaker, Endocrine Grand Rounds, University of Illinois Medical School, Chicago, IL

2001  Speaker, Osteoporosis Symposium, Children’s Hospital, Boston, MA

2001 Speaker, Endocrine Grand Rounds, University of Toronto, ON

2001 Speaker, Endocrine Grand Rounds, Brigham Women’s Hospital, Boston, MA

2001 Speaker, Pediatric Endocrine Grand Rounds, Children’s Hospital, Boston, MA

2001 Speaker, Medical Grand Rounds, University of Massachusetts Medical Center, Worcester, MA

2001 Speaker, Endocrine Society Symposium, Denver, CO

2001 Speaker, Clinical Research Symposium, University of Iowa, Iowa City, IO

Educational Program Materials:

1995 Endocrine Society Videotape Educational Series, “Osteoporosis”

1997 American College of Obstetrics and Gynecology Update Audiotape Program, “Osteoporosis”

1997 Medical College of Virginia Teleconferencing Educational Series, “Diagnosis and Treatment of Hyperprolactinemia”

1998 University of New Jersey, Rutgers, Teleconferencing Educational Series, “New Advances in Growth Hormone Therapy”

1998 Medi-Topics Educational Teleconferencing Series, “Advances in Testosterone Therapy”

1998 The Human Growth Foundation, “Adult Growth Hormone Deficiency”, Educational Materials

1998 Strategic Institute for Continuing Health Care Education Teleconferencing Series, “Update on the Treatment of Acromegaly”