ACUTE INFLAMMATORY

INTESTINAL DISORDERS

Any part of the lower GI tract is susceptible to acute inflammation

caused by bacterial, viral, or fungal infection.Two such conditions are appendicitis and diverticulitis,both of which may lead to peritonitis, an inflammation ofthe lining of the abdominal cavity.

Appendicitis

The appendix is a small, fingerlike appendage about 10 cm(4 in) long that is attached to the cecum just below the ileocecalvalve. The appendix fills with

food and empties regularlyinto the cecum. Because it empties inefficiently and itslumen is small, the appendix is prone to obstruction and isparticularly vulnerable to infection (ie, appendicitis).

, is the most common reasonfor emergency abdominal surgery. Although it can occur atany age, it more commonly occurs between the ages of 10and 30 years (NIH, 2007).

Pathophysiology

The appendix becomes inflamed and edematous as a result of becoming kinked or occluded by a fecalith (ie, hardened mass of stool), tumor, or foreign body. The inflammatoryprocess increases intraluminal pressure, initiating a progressively severe, generalized, or per umbilical pain that becomes localized to the right lower quadrant of the abdomen

within a few hours. Eventually, the inflamed appendix fillswith pus.

Clinical Manifestations

Vague epigastric or periumbilical pain (ie, visceral pain thatis dull and poorly localized) progresses to right lower quadrantpain (ie, parietal pain that is sharp, discrete, and welllocalized) and is usually accompanied by a low-grade feverand nausea and sometimes by vomiting. Loss of appetite iscommon. In up to 50% of presenting cases, local tenderness

is elicited at McBurney’s point when pressure is applied. Rebound tenderness (ie, production or intensificationof pain when pressure is released) may be present. The extent of tenderness and muscle spasm and the existenceof constipation or diarrhea depend not so much onthe severity of the appendiceal infection as on the locationof the appendix. If the appendix curls Pain on defecation suggests that the tipof the appendix is resting against the rectum; pain on urinationsuggests that the tip is near the bladder or impingeson the ureter. Some rigidity of the lower portion of the rightrectus muscle may occur. Rovsing’s sign may be elicited by

palpating the left lower quadrant; this paradoxically causeSpain to be felt in the right lower quadrant Ifthe appendix has ruptured, the pain becomes more diffuse;

abdominal distention develops as a result of paralytic ileus, and the patient’s condition worsens. Constipation can also occur with appendicitis. Laxatives administered in this instance may result in perforation of the inflamed appendix. In general, a laxative or cathartic

should never be given when a person has fever, nausea, and abdominal pain.

Assessment and Diagnostic Findings

Diagnosis is based on results of a complete physical examination

and on laboratory findings and imaging studies. Thecomplete blood cell count demonstrates an elevated whiteblood cell count with an elevation of the neutrophils. Abdominal

x-ray films, ultrasound studies, and CT scans mayreveal a right lower quadrant density or localized distentionof the bowel. A pregnancy test may be performed for women

of childbearing age to rule out ectopic pregnancy and beforex-rays are obtained. A diagnostic laparoscopy may be used torule out acute appendicitis in equivocal cases.

Complications

The major complication of appendicitis is perforation of the

appendix, which can lead to peritonitis, abscess formation

(collection of purulent material), or portal pylephlebitis,

which is septic thrombosis of the portal vein caused by vegetative

emboli that arise from septic intestines. Perforation

generally occurs 24 hours after the onset of pain. Symptoms

include a fever of 37.7_C (100_F) or greater, a toxic appearance,

and continued abdominal pain or tenderness.

Medical Management

Immediate surgery is typically indicated if appendicitis is diagnosed.

To correct or prevent fluid and electrolyte imbalance,dehydration, and sepsis, antibiotics and IV fluids are administered until surgery is performed. Appendectomy (ie surgical removal of the appendix) is performed as soon as possible to decrease the risk of perforation. It may be performed using general or spinal anesthesia with a low abdominal

incision (laparotomy) or by laparoscopy. Both laparotomy and laparoscopy are safe and effective in the treatment of appendicitis with perforation. However, recovery

after laparoscopic surgery is generally quicker. Consequently, laparoscopic appendectomy is more common. When perforation of the appendix occurs, an abscess may

form. If this occurs, the patient may be initially treated with antibiotics, and the surgeon may place a drain in the abscess. After the abscess is drained and there is no further evidence

of infection, an appendectomy is then typically performed.

Nursing Management

Goals include relieving pain, preventing fluid volume

deficit, reducing anxiety, eliminating infection due to the

potential or actual disruption of the GI tract, maintaining

skin integrity, and attaining optimal nutrition. The nurse prepares the patient for surgery, which includesan IV infusion to replace fluid loss and promote adequaterenal function and antibiotic therapy to prevent infection.If there is evidence or likelihood of paralytic ileus,a nasogastric tube is inserted. An enema is not administeredbecause it can lead to perforation. After surgery, the nurse places the patient in a semi sitting position.

1Gastric and Duodenal Ulcers

A peptic ulcer is an excavation (hollowed-out area) that forms in

the mucosal wall of the stomach, in the pylorus (opening between

stomach and duodenum), in the duodenum (first part of

small intestine), or in the esophagus. A peptic ulcer is frequently

referred to as a gastric, duodenal, or esophageal ulcer, depending

on its location, or as peptic ulcer disease. Erosion of a circumscribed

area of mucous membrane is the cause (Fig. 37-2).

Table 37-2 page 1015 differences between duodenal and gastric ulcer

Stress ulcer

is the term given to the acute mucosal ulceration of

the duodenal or gastric area that occurs after physiologically stressful

events, such as burns, shock, severe sepsis, and multiple organ

traumas.

Clinical Manifestations

Symptoms of an ulcer may last for a few days, weeks, or months

and may disappear only to reappear, often without an identifiable

cause. Many people have symptomless ulcers, and in 20% to 30%

perforation or hemorrhage may occur without any preceding

manifestations.

As a rule, the patient with an ulcer complains of dull, gnawing

pain or a burning sensation in the midepigastrium or in the

back. It is believed that the pain occurs when the increased acid

content of the stomach and duodenum erodes the lesion and

stimulates the exposed nerve endings. Another theory suggests

that contact of the lesion with acid stimulates a local reflex mechanism

that initiates contraction of the adjacent smooth muscle.

Pain is usually relieved by eating, because food neutralizes.

Sharply localizedtenderness can be elicited by applying gentle pressure to the

epigastrium at or slightly to the right of the midline.

Other symptoms include pyrosis(heartburn), vomiting, constipation

or diarrhea, and bleeding. Pyrosis is a burning sensation

in the esophagus and stomach that moves up to the mouth.

it may be a symptom of a peptic ulcer complication. It results

from obstruction of the pyloric orifice, thepassage of tarry stools.

Medical Management

Methods used include medications, lifestyle changes, and surgical

intervention.

Currently, the most commonly used therapy in the treatment of

ulcers is a combination of antibiotics, proton pump inhibitors,

and bismuth salts that suppresses or eradicates H. pylori; histamine

2 (H2) receptor antagonists and proton pump inhibitors are

used to treat NSAID-induced and other ulcers not associated

with H. pylori ulcers.

STRESS REDUCTION AND REST

Reducing environmental stress requires physical and psychological

modifications on the patient’s part as well as the aid and cooperation

of family members and significant others,

SMOKING CESSATION

Studies have shown that smoking decreases the secretion of bicarbonate

from the pancreas into the duodenum, resulting in increased

acidity of the duodenum.

DIETARY MODIFICATION

The intent of dietary modification for patients with peptic ulcers

is to avoid oversecretion of acid and hypermotility in the GI tract.

These can be minimized by avoiding extremes of temperature

and overstimulation from consumption of meat extracts, alcohol,

coffee (including decaffeinated coffee, which also stimulates acid

secretion) and other caffeinated beverages, and diets rich in milk

and cream (which stimulate acid secretion). In addition, an effort

is made to neutralize acid by eating three regular meals a day.

Small, frequent feedings are not necessary as long as an antacid or

a histamine blocker is taken. Diet compatibility becomes an individual

matter: the patient eats foods that can be tolerated and

avoids those that produce pain.

.

SURGICAL MANAGEMENT

The introduction of antibiotics to eradicate H. pylori and of H2

receptor antagonists as treatment for ulcers has greatly reduced the

need for surgical interventions. However, surgery is usually recommended

for patients with intractable ulcers (those that fail to heal

after 12 to 16 weeks of medical treatment

include vagotomy, with or without pyloroplasty, and the Billroth I

NURSING DIAGNOSES

Based on the assessment data, the patient’s nursing diagnoses may

include the following:

• Acute pain related to the effect of gastric acid secretion on

damaged tissue

• Anxiety related to coping with an acute disease

• Imbalanced nutrition related to changes in diet

• Deficient knowledge about prevention of symptoms and

management of the condition

Nursing Interventions

RELIEVING PAIN

Pain relief can be achieved with prescribed medications. The patient

should avoid aspirin, foods and beverages that contain caffeine, and

decaffeinated coffee, and meals should be eaten at regularly paced

intervals in a relaxed setting. Some patients benefit from learning

relaxation techniques to help manage stress and pain and to enhance

smoking cessation efforts.

REDUCING ANXIETY

The nurse assesses the patient’s level of anxiety. Patients with peptic

ulcers are usually anxious, but their anxiety is not always obvious.

Appropriate information is provided at the patient’s level of

understanding

MAINTAINING OPTIMAL NUTRITIONAL STATUS

The nurse assesses the patient for malnutrition and weight loss.

After recovery from an acute phase of peptic ulcer disease, the patient

is advised about the importance of complying with the medication

regimen and dietary restrictions

MONITORING AND MANAGING

POTENTIAL COMPLICATIONS

Hemorrhage

Perforation and Penetration

Perforation is the erosion of the ulcer through the gastric serosa

into the peritoneal cavity without warning

Pyloric Obstruction

Pyloric obstruction, also called gastric outlet obstruction (GOO),

occurs when the area distal to the pyloric sphincter becomes

scarred and stenosed from spasm or edema or from scar tissue