Curriculum vitae- Dr. Iain Searle

Curriculum Vitae

Personal Details

Name:Iain Robert Searle

Countryof birth and current residence: Australia

University Education:

  • PhD research: Departments of Biochemistry and School of Food and Land Sciences, University of Queensland. Supervisor Assoc. Prof. Carroll. Awarded in 2004
  • Undergraduate: Bachelor of Agricultural Science (First Class Honours) Major in Molecular and Quantitative Genetics, University of Queensland, Brisbane, Australia.

Research Experience post PhD:

  • ARC Future Fellow and Laboratory Head (July 2014-current) The University of Adelaide, School of Medical and Biomedical Sciences and School of Agriculture Food and Wine, Adelaide, Australia.
  • ARC QEII Research Fellow and Laboratory Head (The University of Adelaide, School of Medical and Biomedical Sciences and School of Agriculture Food and Wine Adelaide(March 2013- June 2014), The Australian National University, Research School of Biology, Canberra, Australia (October 2009- February 2013).
  • Wellcome Trust Value-in-People Research Fellow (October 2008- September 2009) University of Cambridge, Cambridge, United Kingdom.
  • Marie Curie Postdoctoral Fellow (March 2006- September 2008) The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom.
  • Postdoctoral Fellow (April 2002- February 2006) Max Planck Institute for Plant Breeding Research, Dept of Plant Developmental Biology, Koeln, Germany.

Research Publications:

  • Widespread occurrence and conservation of tRNA and rRNA RNA methylation in the kingdom Plantae. Burgess, A., David, R., and Searle, I.under review at BMC Biology (16/11/2014).
  • microRNAs complement DNAmethylation in controlling developmental canalization in the honeybee female and male castes. Ashby, A., Foret, S., Searle, I., Maleska, R. under review at Nature Communications (09/10/2014).
  • Cazzonelli, C.I., Vanstraelen, M., Simon, S., Yin, K., Carron-Arthur, A., Nisar, N., Tarle, G., Cuttriss, A.J., Searle, I.R., Benkova, E., Mathesius, U., Masle, J., Friml, J., Pogson, B.J. (2013) PLoS One. 8(7): e70069.
  • Campoli, C., Drosse, B., Searle, I., Coupland, G., von Korff, M. (2012) Functional characterisation of HvCO1, the barley (Hordeum vulgare) flowering time ortholog of CONSTANS. Plant J 69(5): 868-880.
  • Castro, M. I., Loef, I, Bartetzko, L., Searle, I., Coupland, G., Stitt, M., Osuna, D. (2011) Nitrate regulates floral induction in Arabidopsis, acting independently of light, gibberellin and autonomous pathways.Planta 233(3): 539-552.
  • Searle, I.R., Pontes, O., Melnyk, C.W., Smith, L.M., Baulcombe, D.C. (2010) JMJ14, A JmjC domain protein, is required for RNA silencing and cell-to-cell movement of an RNA silencing signal in Arabidopsis. Genes & Development 24(10): 986-991.
  • Indrasumunar, A., Searle, I., Lin, M., Kereszt, A., Men, A., Carroll, B., Gresshoff, P. (2010) Nodulation Factor Receptor Kinase 1α Controls Nodule Organ Number in Soybean (Glycine max L. Merr.).Plant J65(1):39-50.
  • Indrasumunar, A., Kereszt, A., Searle, I. Miyagi, M., Li, D., Nguyen, C.D., Men, A., Carroll, B.J. and Gresshoff, P.M. (2010) Inactivation of duplicated nod factor receptor (NFR5) genes in recessive loss-of-function non-nodulation mutants of allotetraploid soybean (Glycine max L. Merr.). Plant Cell Physiology 21(2): 201-214.
  • Huang, L., Jones, A., Searle, I., Patel, K., Vogler, H., Hubner, N.C., Baulcombe, D. (2009) An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature Structural Molecular Biology 16(1): 91-93.
  • Smith, L., Pontes, O., Searle, I., Elina, N., Yousafzai, F. K., Herr, A. J., Pikaard, C. S. Baulcombe, D. (2007) An SNF2 protein associated with nuclear RNA silencing and spread of a silencing signal between cells in Arabidopsis.Plant Cell 19 (5): 1507-1521.
  • Corbesier, L., Vincent, C., Jang, S., Fornara, F., Fan, Q., Searle, I., Giakountis, A., Forrona, Gissot, L., Turnbull, C., Coupland, G. (2007) FT protein movement contributes to long-distance signaling in floral induction in Arabidopsis. Science316(5827):1030-1033.
  • Searle, I.R., Yuehui, H., Turck, F., Vincent, C., Fornara, F., Kroeber, S., Amasino, R., Coupland, G. (2006) The transcription factor FLC confers a flowering response to vernalisation by repressing meristem competence and systemic signalling in Arabidopsis. Genes & Development 20(7): 898-912.
  • Benwith, K., Searle*, I., Ravenscroft, D., Koncz, C., Batschauer, A., Coupland, G., Sommisch, I., Ulker, B. (2005) A rapid one-step nucleic acid extraction procedure and a polymorphic DNA marker set between Arabidopsis accessions Columbia and Landsberg. Plant Methods 1(1):4
  • Searle, I. R., Men, A. E., Laniya, T. S., Buzas, D. M., Ormaetxe, I. T., Carroll, B. J. and Gresshoff, P. M. (2003) Long-Distance Signaling in Nodulation Directed by a CLAVATA1-like Receptor Kinase. Science 299: 109-112.
  • Men, A.E., Laniya, T.S., Searle, I. R., Iturbe-Ormaetxe, I., Gresshoff, I., Jiang, Q., Carroll, B.J.and Gresshoff, P.M. (2003) Fast neutron mutagenesis of soybean (Glycine soja L.) produces a supernodulating mutant containing a large deletion in linkage group H. Genome Letters1:1-9
  • Waldron, J., Peace, C., Searle, I. R., Furtado, A., Wade, N., Graham, M., Carroll, B. J. (2002) Randomly Amplified DNA Fingerprinting (RAF): a culmination of DNA marker technologies based on arbitrary PCR amplification. Journal of Biomedicine and Biotechnology 2(3): 1-10.
  • May, K. J., Whisson, S. C., Zwart, R. S., Searle, I. R., Irwin, J. A. G., Maclean, D. J., Carroll, B. J. and Drenthe, A. (2002) Inheritance and mapping of eleven avirulence genes in Phytophthora sojae. Fungal Genetics and Biology37 (1): 1-12.
  • Schenk, G., Ge, Y., Carrington, L. E., Wynne, C. J., Searle, I. R., Carroll, B. J., Hamilton, S., de Jersey, J. (1999) Binuclear Metal Centers in Plant Purple Acid Phosphatases: Fe-Mn in Sweet Potato and Fe-Zn in Soybean. Archives of Biochemistry and Biophysics 370 (2): 183-189.

* Joint first author

Invited Reviews or Commentaries:

  • Burgess, A. and Searle, I. (2011) The clock primes defense at dawn. Immunology and Cell Biology, 89: 661-662.
  • Gursanscky, N., Searle, I., Carroll, B. J. (2011) Mobile microRNAs hit their target. Traffic, doi:10.1111/j.1600-0854.2011.01253.x.
  • Searle, I., Mosher, R., Melnyk, C., Baulcombe, D. (2007) Gene Silencing: the Biology of Small RNAs and the Epigenome - New Phytologist, 174(3): 479-82.
  • Searle, I. R., Coupland, G. (2004) Induction of flowering by seasonal changes in photoperiod, EMBO J. 2004; 23(6): 1217-22.

Provisional Patent Application

  • Method for creating wide crosses in agricultural crops, Inventors Lohe & Searle (PCT6864484) Submitted in 2013.

Invited keynote and other addresses(in the last 6 years)

International meetings

  • QMB Plant Molecular Biology meeting, invited speaker, part travel and all registration and accommodation expenses paid (Queenstown, 2014)
  • 3rdInternational Symposium on Plant Reproductive Development, all travel, accommodation and registration expenses paid, invited session speaker (Shanghai, 2013)
  • Japan Australia Joint Symposium on Plant Sciences for Agriculture- Keynote speaker, all travel and registration expenses paid (Hokkaido, 2012)
  • International Botanical Congress- invited session speaker (Melbourne, 2011)
  • Emerging Topics in Plant Sciences Meeting- invited session speaker (Oxford, 2008)

National meetings

  • Epigenomics in the Capital- invited session speaker (Canberra, 2012)
  • Genetics society of Australasia annual meeting- invited session speaker (Canberra, 2009)

Review editorial board member

  • Frontiers in Plant Genetic and Genomics

Ad hoc scientific reviewer for

  • The Plant Cell
  • The Plant Journal
  • Proceedings of the National Academy of Sciences
  • Nature
  • Science

Competitive grants awarded:

  • GRDC E-Innovation award- EzyCross- Investigator Searle (2013)
  • CSIRO SEIF top-up PhD scholarship- Investigators Searle and Helliwell (2011-2013)
  • ARC Discovery Grant DP110103805-Investigators Searle, Tremethickand Helliwell (2011-2013)
  • ARC Discovery Grant DP0988846-Investigator Searle (2009-2014)
  • QEII ARC Independent Fellowship DP0988846-Searle (2009-2014)
  • Wellcome Trust Value-In-People Award- Searle (2008-2009)
  • Epigenome travel scholarship- Searle (2007)
  • Marie Curie International Incoming Fellowship- Searle (2006-2007)

Translation grant(s) awarded:

  • ANU Connect Ventures, Direct Translation Fund- InvestigatorsLohe and Searle (2012)

Conference posters presented at international meetings (in the last five years):

  • Jones, A., Searle, I. Identification of long non-coding RNAs in developing siliques of Arabidopsis thaliana. Keystone meeting on RNA silencing. Whistler, Canada, (2013).
  • Searle, I., Smith, L., Baulcombe, D. Identification of two novel histone modifying proteins required for RNA silencing in Arabidopsis. 2nd European conference on MicroRNAs: Biology to Development and Disease. Cambridge, UK (2007).

Teaching activities (ANU)

  • BIOL3161- Genomics and it’s Applications (2010-2012)
  • BIOL3181- Developmental and Molecular Biology (2010, 2011)
  • BIOL2162- Molecular Biotechnology, (2010- 2012)
  • BIOL3208- Research Project, (2011)
  • BIOL8703- Master research proposal, (2011)
  • Advanced Study Course- PhB student elective, (2012)

Formal mentoring of ANU PhB (Bachelor of Philosophy) students

  • Samantha Lambe (2nd year undergraduate student at ANU)
  • Imogen Moran (3rd year undergraduate student at ANU)

Course Convenorship (ANU

  • PhB Biology Program (Semester 1 2012)

Teaching activities (community)

  • Teacher Scientists Network- Swaffham Primary School (UK, 2006, 2007)
  • Scientists in School- North Ainslie Primary School (AUS, 2011, 2012)

Professional Memberships

  • Genetics society of AustralAsia
  • The Genetics Society (UK)
  • Australian Society of Plant Biologists

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