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Name: Sarwat Fatima

Academic qualifications:

09/2000-08/2003 / BSc (Hons) / The Hong Kong Polytechnic University
09/2003-08/2005 / MPhil / The Hong Kong Polytechnic University
09/2008-08/2011 / PhD / The University of Hong Kong

Work experience:

09/2012-Present / Post-doctoral research fellow / Hong Kong Baptist University
09/2010-03/2011 / Research postgraduate exchange student / The National University of Singapore
04/2008-08/2008 / Research assistant / The University of Hong Kong
01/2007-03/2008 / Technical writer / Hai Kang Life Corporation Limited, Hong Kong
06/2002-08/2002 / Research student / Chr. Hansen, Denmark

Book chapters:

Kenneth K. Lai, Kin-Tak Chan, Sarwat Fatima, Nikki P. Lee, Simon Law. In: New Advances on Disease Biomarkers and Molecular Targets in Cancer and Biomedicine. Springer Publishers, 2013. (invited book chapter).

Felix H. Shek, Tracy C.W. Lai, Sarwat Fatima, Nikki P. Lee. In: New Advances on Disease Biomarkers and Molecular Targets in Cancer and Biomedicine. Springer Publishers, 2013. (invited book chapter).

Luk JM, Fatima S, Lee NP, Fan ST. Liver cancer biomarkers. In: Dan Hellberg (Ed.),Textbook - Histological and serological tumor markers and their clinical usefulness in cancer. Nova Publishers Inc, New York, USA, 2008. (invited textbook chapter)

Publication in Peer-reviewed Journals:

Fatima S, Luk JM and Lee NP. Dysregulated expression of dickkopfs (DKKs) for potential detection of hepatocellular carcinoma. Expert Reviews in Molecular Diagnostics (in submission). Impact factor 4.089

Shek FH, Fatima S, Lee NP. Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma. Int J Hepatol, 2012.

Fatima S, Lee NP, Tsang FH, Kolligs FT, Ng IOL, Poon RTP, Fan ST, Luk JM. Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway via influencing β-catenin in hepatocellular carcinoma. Oncogene, 20;31(38):4233-4244 (2012). Impact factor 6.373

Fatima S, Lee NP, Luk JM. Dickkopfs (DKKs) and Wnt/β-catenin signalling in liver cancer. World Journal of Clinical Oncology, 2(8):311-325 (2011).

Tung KK, Mak KM, Fatima S, Lo CL, Heng Z, Zhang C, Dai H, Poon RTP, Yuen MF, Lai CL, Li J, Luk JM, Ng IOL. Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma. Liver International, 31(10):1494-1504 (2011). Impact factor 3.824

Hu MY, Lam CT, Liu KD, Xu MZ, Fatima S, Su YC, Tsang FH, Chen J, Pang JZ, Win LX, Luk JM. Proteomic identification of a monoclonal antibody recognizing Caveolin-1 in hepatocellular carcinoma with metastatic potential. Protein Peptide Letters, 16(5):479-485 (2009). Impact factor 1.942

Lu WJ, Lee NP, Fatima S, Luk JM. Heat shock proteins and cancer: signaling pathways, tumor markers and molecular targets in liver malignancy. Protein Peptide Letters, 16(5):508-516 (2009). Impact factor 1.942

Tang WK, Chui CH, Fatima S, Kok SHL, Pak KC, Ou TM, Hui KS, Wong MM, Wong J, Law S, Tsao SW, Lam KY, Beh PHL, Srivastava G, Ho KP, Chan ASC, Tang JCO. Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma. International Journal of Molecular Medicine, 19(6):953-960 (2007). Impact factor 1.573

Tang WK, Chui CH, Fatima S,Kok SHL, Pak KC, Ou TM, Hui KS, Wong MM, Wong J, Law S, Tsao SW, Lam KY, Beh PSL, Srivastava G, Chan ASC, Ho KP, Tang JCO. Oncogenic properties of a novel gene (JK-1) located in chromosome 5p and its overexpression in human esophageal squamous cell carcinoma. International Journal of Molecular Medicine, 19(6):915-923 (2007). Impact factor 1.573

Fatima S, Chui CH, Tang WK, Hui KS, Au HW, Li WY, Wong MM, Cheung F, Tsao SW, Wong J, Law S, Srivastava G, Ho KP, Chan ASC, and Tang JCO. Transforming capacity of two novel genes JS-1 and JS-2 located in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma. International Journal of Molecular Medicine, 17(1), 159-170 (2006). Impact factor 1.573

Chui CH, Cheng GYM, Ke B, Lau FY, Wong RSM, Kok SHL, Fatima S, Cheung F, Cheng CH, Chan ASC, Tang JCO. Growth inhibitory potential of effective microorganism fermentation extract (EM-X) on cancer cells. International Journal of Molecular Medicine, 14(5), 925-929 (2004). Impact factor 1.573

Chui CH, Tang JCO, Lau FY, Teo ITN, Yau MYC, Wong RSM, Cheng GYM, Ho SKW, Leung TWT, Hui KS, Wong MM, Fatima S, Cheng CH, Cheung F, Tan WQ, Chow LMC, Guo DA, Chan ASC. Gleditsia sinensis fruit extract induced growth inhibition involves basic fibroblast growth factor and nitric oxide. International Journal of Molecular Medicine, 13(1), 169-173 (2004). Impact factor 1.573

Conference papers

Fatima S, Lee NP, Luk JM. Roles of DKK4 on wnt signaling in hepatocellular carcinoma. Yong Loo Lin School of Medicine, First Graduate Student Congress, The National University of Singapore, January 25, 2011.

Fatima S, Lee NP, Luk JM. Roles of DKK4 on wnt signaling in hepatocellular carcinoma. 15th Research Postgraduate Symposium, The University of Hong Kong, December 1, 2010.

Fatima S, Lee NP, Luk JM. Roles of DKK4 on wnt signaling in hepatocellular carcinoma. Frontiers in Cancer Science, Singapore, November 8–10, 2010.

Fatima S, Lee NP, Luk JM Roles of DKK4 on wnt signaling in hepatocellular carcinoma. 20th Conference on the Asian Pacific Association for the Study of the Liver, Beijing, China, March 25-28, 2010.

Fatima S, Lee NP, Luk JM. Roles of DKK4 on wnt signaling in hepatocellular carcinoma. 14th Research Postgraduate Symposium, The University of Hong Kong, December 10, 2009.

Tang WK, Fatima S, Chui CH, Ou TM, Hui KS, Wong MM, Wong J, Law S, Tsao GSW, Lam KY, Beh PSL, Srivastava G, Ho KP, Tang JCO. Oncogenic properties of a novel gene located in chromosome 5p and its overexpression in human esophageal squamous cell carcinoma. Proceedings at the 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan, June 18-23, 2006

Fatima S, Hui KS, Wong MM, Tang WK, Chui CH, Wong J, Law S, Tsao GSW, Srivastava G, Ho KP, Tang JCO. Study of transforming capacity of two novel genes JS-1 and JS-2 in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma. Proceedings at the 96th Annual Meeting, American Association for Cancer Research, Anaheim, CA, USA, April 16-20, 2005.

Lau FY, Chui CH, Cheng GYM, Ke B, Wong RSM, Teo ITN, Fatima S, Kok SHL, Chan ASC, Tang JCO. Growth inhibitory potential of effective microorganisms fermentation extract (EM-X) on cancer cells. Proceedings at the 9th World Congress on Advances in Oncology and 7th International Symposium on Molecular Medicine, Hersonissos, Crete, Greece, October 14-16, 2004.

Hong Kong

Chui CH, Tang JCO, Lau FY, Wong RSM, Cheng GYM, Hui KS, Wong MM, Fatima S, Chow LMC, Gou DA, Chan ASC. Basic fibroblast growth factor and nitric oxide are involved in the growth inhibition induced by Gleditsia sinensis fruit extract. Proceedings at the 10th Hong Kong International Cancer Congress, Hong Kong, Nov 19-21, 2003.