1021, either, cat: 11
SENSITIVITY, SPECIFICITY, POSITIVE PREDICTIVE VALUE, AND NEGATIVE PREDICTIVE VALUE OF STRESS TESTING VERSUS 64-CHANNEL MULTISLICE CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY IN PREDICTING OBSTRUCTIVE CORONARY ARTERY DISEASE DIAGNOSED BY CORONARY ANGIOGRAPHY
H.M. Lai, W.S. Aronow, G. Ravipati, J. Shao, A.J. DeLuca, M.B. Weiss, A.L. Pucillo,
K. Kalapatapu, C.E. Monsen, R.N. Belkin
New York Medical College, Valhalla, NY, USA
Background: Stress testing and 64-channel multislice coronary computed tomography angiography (CTA) are used to predict obstructive coronary artery disease (CAD). Methods: 64-channel multislice coronary CTA, stress testing, and coronary angiography were performed in 47 patients with suspected CAD. Obstructive CAD was diagnosed if there was > 50% diameter narrowing of at least 1 major coronary artery. Stress testing was performed using a sestamibi stress test in 31 patients, an adenosine sestamibi stress test in 13 patients, and a dipyridamole stress test in 3 patients. The 47 patients included 31 men and 16 women, mean age 66 years.
Results: >50% diameter narrowing of at least 1 major coronary artery was diagnosed in 36 of 47 patients (77%). The sensitivity of stress testing was 69% and of coronary CTA was 100% in predicting obstructive CAD. The specificity of stress testing was 36% and of coronary CTA was 73% in predicting obstructive CAD. The positive predictive value (PPV) of stress testing was 78% and of coronary CTA was 92% in predicting obstructive CAD. The negative predictive value (NPV) of stress testing was 27 % and of coronary CTA was 100% in predicting obstructive CAD.
Conclusions: The sensitivity, specificity, PPV, and NPV were higher for coronary CTA than for stress testing in predicting obstructive CAD.