Ogilvy-XXX
Prepared: 8/03
Name: Christopher Stanley Ogilvy, M.D.
Office Address: Neurosurgery, VBK710, Massachusetts General Hospital
55 Fruit Street, Boston MA 02114
Home Address:
E-Mail: Fax: 617/726-7501
Place of Birth:
Education:
1980 B.A. Yale University, New Haven CT (biology)
Magna cum laude
1984 M.D. Dartmouth Medical School, Hanover NH
With Honors
Postdoctoral Training:
Internships and Residencies:
1984-1985 Intern, General Surgery, The Presbyterian Hospital, Columbia-Presbyterian Medical Center, New York NY
1985-1991 Resident in Neurosurgery, Massachusetts General Hospital, Boston MA
Research Fellowships:
1982 Surgical Research Fellowship, Dartmouth Medical School, Hanover NH
1987-1989 Dana Foundation Research Fellowship in Neuroscience
Licensure and Certification:
1990 Massachusetts License Registration
1995 American Board of Neurological Surgery
Academic Appointments:
1991-1996 Assistant Professor of Surgery, Harvard Medical School
1996- Associate Professor of Surgery, Harvard Medical School
Hospital Appointments:
1990-1991 Assistant in Neurosurgery, Massachusetts General Hospital
1991-1995 Assistant Visiting Neurosurgeon, Massachusetts General Hospital
1996- Associate Visiting Neurosurgeon, Massachusetts General Hospital
1993- Director, Cerebrovascular Surgery, Massachusetts General Hospital
Hospital and Health Care Organization Service Responsibilities:
1991- Clinical Neurosurgeon, Cerebrovascular Surgery, Massachusetts General Hospital
1993- Director, Cerebrovascular Surgery, Massachusetts General Hospital
1993- Co-Director, MGH Brain Aneurysm/AVM Center, Massachusetts General Hospital
2000- Co-Director, Neurosurgical Operating Rooms, Massachusetts General Hospital
Major Committee Assignments:
Affiliated Institution
1993- Clinical Practice Committee, Neurological/Neurosurgical Intensive Care Unit, Member, MGH
1994- Quality Assurance Committee, Neurosurgical Representative, MGH
1994 Aneurysm Quality Improvement Team (Clinical Pathways), Member, MGH
1995-2000 Tertiary/Quarternary Strategic Planning Task Force Committee, Member, MGH
1995-2000 Cerebrovascular Disease Quality Improvement Task Force, Member, MGH
1995-2000 Neurology/Neurosurgery Operations Improvement Committee, Workgroup leader, MGH
2000- Clinical Performance Management Committee, CH/MGPO Partnership in Medical Management, Neurosurgery Representative, MGH
2000- Neurosurgical Quality Assurance/Safety Committee, Chairman, MGH
2001- MGH Integrated Vascular Disease Program Task Force, Member, MGH
2001- Operating Room Management Group, Member, MGH
2001- Operating Room Quality Assurance/Safety Committee, Member, MGH
2001 MGH Neurosurgical Society, Secretary/Treasurer, MGH
2003- MGH Vascular Center Operations Committee, Member, MGH
2003- MGH Vascular Center Quality Assurance Committee, Member, MGH
2003- MGH Vascular Center Education Committee, Member, MGH
National and Regional
1993-96 AVM Association Medical Advisory Board, Director
1994- National Brain Aneurysm Foundation, Executive Director
1994- National Brain Aneurysm Foundation Medical Advisory Board, Director
1994- Cavernous Malformation Foundation, Medical Advisory Board Member
1999 American Board of Neurological Surgeons, Oral Boards Examiner
1999- Boston Operation Stroke, Medical Subcommittee, Member
2000- Boston Operation Stroke, Medical Subcommittee, Cochair
2001- New England Neurosurgical Society, Board of Trustees Member
2003- New England Neurosurgical Society, Treasurer
Professional Societies:
1986- Massachusetts Medical Society, Member
1986-1991 Congress of Neurologic Surgeons, Resident member
1990- Boston Stroke Society, Member
1991- New England Neurosurgical Society, Member
1992 Congress of Neurologic Surgeons (Provisional member)
1992 Congress of Neurologic Surgeons, Registration Committee
1992- International Stereotactic Radiosurgery Society, Member
1992- American Association of Neurological Surgeons, Member
1992 American Association of Neurological Surgeons, Sergeant at Arms
1993- Congress of Neurological Surgeons, Member
1993- Joint Section on Cerebrovascular Surgery, AANS/CNS, Member
1993- American Heart Association, Stroke Council member
1993- Society for Neuroscience, Member
1994-95 4th International Workshop on Cerebrovascular Surgery, Organizing Committee
1995- Brain Attack Coalition, Faculty Volunteer
1995- Congress of Neurological Surgeons, Membership Committee
1995-1999 Joint Section on Cerebrovascular Surgery (AANS/CNS) Representative, Joint Council of Neurosurgical Societies
1995-1999 Joint Section on Cerebrovascular Surgery, AANS/CNS, Membership Committee
1996- Joint Section on Cerebrovascular Surgery, AANS/CNS, Outcomes and Guidelines Committee (Ischemia Subcommittee)
1996- Joint Section on Cerebrovascular Surgery, JSCVS/ASITN Annual Meeting Abstract Committee
1996-1998 Joint Section on Cerebrovascular Surgery, AANS/CNS, Membership Chairman
1997- Joint Section on Cerebrovascular Surgery, JCVS/ASITN Annual Meeting Scientific Program Committee
1998-2000 Joint Section on Cerebrovascular Surgery, AANS/CNS, Member-at-Large, Executive Committee on Cerebrovascular Disease
1999 Joint Section on Cerebrovascular Surgery, JSCVS/ASITN Annual Meeting Abstract Committee
1999-2000 Task Force to Define Guidelines in the Current Management of Cerebral AVMs, Chairman, Joint Section on Cerebrovascular Surgery
2000 Joint Section on Cerebrovascular Surgery, AANS/CNS, Program Chairman, Congress of Neurological Surgery, 2000 Annual Meeting
2000 Congress of Neurological Surgeons, 2000 Annual Meeting Abstract Committee
2000 Joint Section on Cerebrovascular Surgery, AANS/CNS, Annual Meeting Planning Committee
2000 Joint Section on Cerebrovascular Surgery, JSCVS/ASITN Annual Meeting, Co-Chairman, Luncheon Seminars
2000 Joint Section on Cerebrovascular Surgery, 2001 Annual Meeting Abstract Committee
2000 First Joint American-Japanese Meeting for Surgical and Endovascular Treatment of Cerebrovascular Disorders, Member, Scientific Program Committee
2000- American Academy of Neurological Surgery, Member
2001- Neurosurgical Society of America, Member
2002-2003 Neurosurgical Society of America, Program Committee Member
Editorial Boards:
1995- Ad hoc reviewer, Journal of Neurosurgery
1995- Ad hoc reviewer, New England Journal of Medicine
1995- Ad hoc reviewer, Stroke
1996- Editorial Board, Journal of Neurovascular Disease
1996- Editorial Review Board Member, Neurosurgery
2000- Ad hoc reviewer, Mayo Clinic Proceedings
2000- Ad hoc reviewer, Surgical Neurology
Awards and Honors:
1980 Magna cum laude, Yale University
1983 Alpha Omega Alpha Honor Society (junior year, president), Dartmouth Medical School
1984 M.D. with Honors, Dartmouth Medical School
1990 American Association of Neurological Surgery—first prize, poster program, 1990 meeting
1992 Charles A. Elsberg Fellowship: Protection of CNS tissue from ischemia
1993 Teacher of the Year, Neurosurgical Service, Massachusetts General Hospital
1998 Nominee, Prize for Excellence in Teaching, Harvard Medical School
II. Research, Teaching, and Clinical Contributions
A. Narrative description of research, teaching and clinical responsibilities
Research interests include both clinical and basic laboratory efforts. Clinical research efforts are primarily targeted at examining outcome measures for patients undergoing procedures for cerebrovascular disease. This includes patients for carotid endarterectomy, brain arteriovenous malformations, and intracranial aneurysms. Development of combined modality management of endovascular and surgical techniques for the management of cerebrovascular disease is also a major research interest. Techniques have been developed to help minimize ischemic injury during neurovascular procedures. Studies continue in the use of mild hypothermia during surgical procedures. In the laboratory, efforts have focused on techniques and strategies to minimize the impact of brain injury or ischemia and are now being extended to fever control in the ICU as well as use during stroke. Specifically, strategies of hypothermia, induced systemic hypertension, and metabolic suppression using a variety of techniques and agents are used. An in vitro model of retinal ischemia is used to screen techniques, and an in vivo model inducing middle cerebral artery stroke is used in rats and rabbits to test the different strategies and assess their efficacy.
B. Funding Information:
Past: 1987-1989 Dana Foundation PI
Effect of peripheral innervation on trophic function of peripheral tissue
1995-1996 The Upjohn Company PI
Tirilazad mesylate in women with subarachnoid hemorrhage: 33% increase in dose over last trial
1994-1999 NIH/NINDS/K08 PI
Avoiding stroke during cerebrovascular surgery
Current: 1991- NIH MGH PI
International study of unruptured intracranial aneurysms
2000- Innercool Therapies PI
Inducing mild hypothermia for surgery of unruptured intracranial aneurysms
C. Report of current research activities (bench research, clinical trials, outcome studies, efficacy studies)
Bench research: “Tissue engineered bioabsorbable polymers seeded with autologous cell components for endovascular occlusion of experimental aneurysms: permanent aneurysm occlusion by formation of neoendothelium across the aneurysm ostium.” Collaborators: Brian Hoh, Joseph Vacanti, Johnny Pryor
Clinical trials: “Efficacy and safety of Innercool indwelling venous catheter used to maintain moderate hypothermia during unruptured aneurysm surgery.”
Outcome studies: “Effect of smoking on outcome in the management of ruptured intracranial aneurysms.”
“Effect of smoking on outcome from ruptured intracranial aneurysms”
“Risk stratification in the surgical management of unruptured intracranial aneurysms”
“Outcome determinants and efficacy of endovascular coiling of intracranial aneurysms:
D. Report of Teaching:
1. Local Contributions
a. Medical school courses
1992- Neurosurgery Elective
Organizer, medical student elective curriculum
3rd and 4th year students
1-4 students, 3 sessions per month, 1.5 hrs each
b. Graduate medical course
1991- Neurosurgery Grand Rounds
Lecturer
50-75 residents and staff members
3 hours per lecture (44 lectures total, approximately 6 per year)
1991- Grand Rounds/Hospital Lectures (Neurology/Neuropathology/
Medical or Surgical Grand Rounds)
Lecturer
20-50 staff physicians
2 hours per lecture (28 lectures total, approximately 3 or 4 per year)
c. Local invited teaching presentations
1992 "Clinical decision making and analysis" with Dr. Mark Ecker
New England Medical Center, Boston MA
"Radiosurgery for AVMs" with Dr. Chapman
Neurology/Neurosurgery Grand Rounds, New England Medical Center, Boston MA
1993 "Current management of subarachnoid hemorrhage"
Medical Grand Rounds, Mt Auburn Hospital, Cambridge MA
1995 "Recent advances in the surgical management of cerebral aneurysms"
Anesthesia and Critical Care Grand Rounds, Beth Israel Hospital, Boston MA
1996 "Current management of intracranial aneurysms"
Medical Grand Rounds, Cambridge Hospital, Cambridge MA
"Diagnosis and management of intracranial aneurysms"
Medical Grand Rounds, Deaconess Hospital, Boston MA
"Predicting outcome from aneurysm surgery"
Neurosurgery Grand Rounds, Brigham and Women's Hospital, Boston MA
1998 "Management of subarachnoid hemorrhage"
Acute Stroke Management Workshop, Boston MA
"Outcome from surgical management of intracranial aneurysms"
Distinguished Lecture Series, Spaulding Rehabilitation Hospital, Boston MA
2000 "Acute diagnosis and management of subarachnoid hemorrhage", Speaker
Emergency Room Medicine Grand Rounds, Brigham and Women's Hospital, Boston MA
2001 "Current diagnosis and management of intracranial aneurysms and subarachnoid hemorrhage", Speaker, Medical Grand Rounds, Cambridge Hospital, Cambridge MA
“Surgical and endovascular treatment of aneurysms”, Speaker
Spaulding Rehabilitation Hospital, Boston MA
2002 “Surgical and endovascular techniques for stroke prevention and treatment”, Speaker, Stroke Update 2002: Acute Care and Rehabilitation Issues course, Whittier Rehabilitation Hospital and UMass Memorial Hospital, Westborough MA
“What is an aneurysm: the facts”, Speaker, Brain Aneurysm Awareness Meeting, The Brain Aneurysm Foundation and South Shore Hospital, Weymouth MA
d. Continuing medical education course
1990- Annual National Course on Cerebrovascular Disease (Harvard Medical School Postgraduate course), Course Codirector
1991- Annual Regional Seminar on Stroke/Hemorrhage, Director
e. Advisory and supervisory responsibilities, clinical or lab
1991- Clinical supervisor: 2 residents per year. Direct supervision/neurovascular training for the residency program
1992-2000 Preceptor in lab: guide laboratory members and review data critically; develop research ideas and plan experiments
The number of laboratory members varies, but has generally increased yearly, from 1 per year in 1992 to 9 in 1999
500 hours per year total:
Undergraduate student sponsor
1-3 students in laboratory/year
Medical student sponsor
1-2 students in laboratory/year
Resident student sponsor
1-2 residents in laboratory/year
Postdoctoral fellows
2-3 postdoctoral fellow in laboratory/year
1996-99 Clinical fellow (cerebrovascular)
Supervisor in operating room, inpatient setting, ambulatory clinic
1 fellow per year
600-800 hours per year
f. Teaching leadership role in department/affiliated institution medical school
1990- Annual National Course on Cerebrovascular Disease (Harvard Medical School Postgraduate course), Course Codirector
1991- Annual Regional Seminar on Stroke/Hemorrhage, Director
g. Names of advisees or trainees
Research trainees
1992-1993 Stuart Kaplan (medical student)
1 year elective in research
current position: Fellow in Pediatric Neurosurgery, Cincinnati Children’s Hospital
1993-1994 Dachen Chu (research fellow)
1 year elective in research
current position: Director of Cerebrovascular Surgery, Taipei Municipal Jen-Ai Hospital, Taipai, Taiwan
1993-1994 Paulo Yanez (medical student)
1 year elective in research
current position: Resident, Mayo Clinic
1993-1994 Ibrahim Saikali (research fellow)
current position: Neurosurgeon, Montreal, Canada
1993-2000 Kenneth I. Maynard, M.Sc., Ph.D.
Postdoctoral Fellow, MGH 1993-98
Assistant Professor, MGH 1998-00
Codirector of Ischemia Laboratory with Dr. Ogilvy
current position: Section Head, Cerebrovascular Disorders,
Aventis Pharmaceuticals, Bridgewater NJ
1994-1995 Pablo M. Arrango, M.D. (postdoctoral research fellow)
current position: Neurosurgical Resident, Colombia, South America
1995 Sepideh Amin-Hanjani, M.D. (neurosurgery resident at MGH)
six month elective in research
current position: Staff Neurosurgeon, Massachusetts General Hospital
1995 R. Joseph Crow, Jr., M.D. (neurosurgery resident at UMass. Medical Center)
six month elective in research
current position: Neurosurgeon, Neurological Associates Inc, Charleston WV
1995-1996 Martin Smrcka, M.D. (research fellow, neurosurgery resident, Czech Republic)
1 year elective in research
current position: Director of Cerebrovascular Surgery, Brno, Czech Republic
1995-1997 David Chen (Harvard/MIT medical student)
summer elective in research
current position: Ophthalmology Resident, Tufts Medical School)
1996-1997 Junaid Malek (undergraduate student, Tufts University)
current position: Department of Neurosurgery, UCSF
1997 Mahmood Hassan, Ph.D. (postdoctoral research fellow)
current position: Neurosurgeon, India
1997-2000 Issam Ayoub, M.D. (postdoctoral research fellow)
current position: Research Fellow, Neurology, Harvard Institute of Medicine
1997-1998 Alfredo Quonones-Hinojosa (HMS student)
Howard Hughes Fellow
current position: Resident in Neurosurgery, UCSF
1998 George Fox (undergraduate student, NYU)
current position: Biology teacher, Northfield Mt. Herman School, MA
1998 Junaid Malek (undergraduate student, Tufts University)
current position: medical student, Chicago IL
1998 Frederick B. Harris (Merck Summer Research Trainee, Ohio State College of Medicine)
current position: Neurosurgical resident, Mississippi
1998 Yohtaro Sakakibara, M.D., Ph.D. (neurosurgeon, medical school, Japan)
current position: Neurosurgeon, Japan
1999 Diamond Tam (medical student, Royal College of Surgeons, Dublin, Ireland
current position: Ophthalmology Resident, USCF
1999 Majestic Tam (undergraduate, Royal College of Surgeons, Dublin, Ireland)
1999, 2000 Alim Mitha (medical student, University of Alberta, Canada)
1999 Djoko Jacques Dutrochet (graduate student, University of Massachusetts)
1999-2000 Chiung-Chyi Shen, M.D. (attending neurosurgeon, Taiwan, PRC)
current position: Attending Neurosurgeon, Taiwan, PRC
2003 Arnold Cheung (medical student. Penn. State University)
Clinical Fellows
1996-98 Shirley I. Stiver, M.D.
(Clinical Fellow in Cerebrovascular Surgery, MGH)
current position: Vascular Growth Factor Lab, Beth Israel Hospital, Boston MA
1998-99 Robert J. Singer, M.D.
(Clinical Fellow in Cerebrovascular Surgery, MGH)
current position: Director of Cerebrovascular Surgery, Middle Tennessee Neurosurgery, Nashville TN
Residents (including current position)
1984-91 John D. Steichen, M.D.
Private neurosurgery practice, Greenwood SC
1985-92 Fred G. Barker, M.D.
Attending Neurosurgeon, Massachusetts General Hospital,
Assistant Professor of Surgery, Harvard Medical School
1987-92 James M. Schumacher, M.D.
Private neurosurgery practice, Sarasota FL
1989-94 Richard M. Westmark, M.D.
Private neurosurgery practice, Houston TX
1988-93 William S. Rosenberg, M.D.
1988-94 William Butler, M.D.
Attending Neurosurgeon, Massachusetts General Hospital
Assistant Professor of Surgery, Harvard Medical School
1989-95 David M. Frim, M.D.
Director of Pediatric Neurosurgery, University of Chicago MC, Chicago IL
1989-95 E. Antonio Chiocca, M.D.
Attending Neurosurgeon, Massachusetts General Hospital
Associate Professor, Harvard Medical School
1990-96 Peyman Pakzaban, M.D.
Private neurosurgery practice, Pasadena TX
1990-96 Nicole N. Moayeri, M.D.
Neurosurgery, Kaiser Permanente, Redwood City CA
1991-96 Stephen B. Tatter, M.D.
Director, BrainTumor Center of Excellence
Co-Director, Gamma Knife Radiosurgery Center
Attending Neurosurgeon, Wake Forest University Medical Center
1992-97 John S. Yu, M.D.
Neurosurgical Institute, Cedars-Sinai Medical Center
1992-97 Robert M. Friedlander, M.D.
Associate Director of Cerebrovascular Surgery, Brigham and Women’s Hospital
Associate Professor of Neurosurgery, Harvard Medical School