Curriculum Vitae
1. Personal details:Given name: / Ke-Qin
Family name: / Zhang
Sex: / male
Birth date: / Dec. 6 1958
Academic position: / Director and professor, Laboratory for Conservation and Utilization of Bioresources, Yunnan University
Address: / 2 North Cuihu Rd. Yunnan University, Kunming, Yunnan P.R.China 650091
Tel: / (86)-0871-5034878 (O); (86)-0871-5031630 (H); Mobile: 13708880184
Fax: / (86)-0871-5034838 (O)
Email: /
2. Educational background:
Sept. 1995-Sept. 1997 / Ph. D. at China Agricultural University, Beijing
Sept. 1986-Sept. 1989 / M. Sc. in agriculture at Yunnan Agricultural University. Kunming, Yunnan
Sept. 1977-Sept. 1981 / B. Sc. in agriculture at Guizhou Agricultural College, Guiyang, Guizhou
3. Working experience
2001--- / Vice-President of Yunnan University
June 1998-June 1999 / Director and professor at Key Laboratory of Microbiology Fermentation of Yunnan Province (attached to Yunnan University), Kunming, Yunnan, China
Nov. 1997-June 1998 / Professor and Assistant to President, Guizhou University, Guiyang, Guizhou, China
Sept. 1995-Oct. 1997 / Professor and Assistant to President, Guizhou Agricultural College, Guiyang, Guizhou, China
Sept. 1992-Aug. 1995 / Associate professor and associate dean, Dept. of Plant Protection, Guizhou Agricultural College, Guiyang, Guizhou, China
Sept. 1990-Sept. 1992 / Lecturer and director of Plant Pathology Lab., Dept. of Plant Protection, Guizhou Agricultural College, Guiyang, Guizhou, China
Sept. 1982-Sept. 1989 / Assistant professor at Dept. of Plant Protection, Guizhou Agricultural College, Guiyang, Guizhou, China
4. Scientific awards
2009 / Awarded with the first prize for “The Molecular Mechanisms of Microorganisms Infect against Nematodes” by Yunnan Provincial government2004 / Awarded with the second prize by Chinese government.
2001 / Awarded with the first prize for "Development and application of biocontrol agent for controlling root-knot nematode " by Yunnan Provincial government
1994 / Awarded with the first prize for "Biocontrol Research of Chinese nematodes-destroying fungal resources", by Guizhou Provincial government
5. Academic memberships
2002-- / Vice-president of Mycological Society of China (MSC)1998- / Vice director of Entomologenous Fungi Subcommittee, MSC
1995-1998 / General Secretary, Mushroom Science Society of Guizhou province
1998- / Member of the Committee, Plant Pathological Society of China
1998 / Member of National Teaching-consultant Council for higher education of agricultural institutions
6.Research interests: Biological control for plant-parasitic nematodes
7. Editorial Services:
Editor in Chief (2001--) in Journal of Yunnan University
Associate Editor(2000-2001) in Fungal Diversity
Executive Editor(2002-2004) in Fungal Diversity
Menber of the Editorial Board(2009--) in Recent Patents on Biotechnology
Menber of the Editorial Board(2005--) in Mycosystema
8. Main publications
160 papers, 3 book were published. The main publications are listed as follows(*Correspoding author)
Lianming Liang, Zhaohui Meng, Fengping Ye, Jinkui Yang, Shuqun Liu, Yuna Sun, Yu Guo, Qili Mi, Xiaowei Huang, Chenggang Zou, Zihe Rao, Zhiyong Lou and Ke-Qin Zhang﹡. 2010, The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contrbution to infection against nematodes The FASEB Journal article fj.09-136408.Published online
Juan li, Li Yu, Jinkui Yang, Linqian Dong, Baoyu Tian, Zefen Yu, Lianming Liang, Ying Zhang, Xu Wang and Ke-Qin Zhang*, New insights into the evolution of subtilisin-like serine protease genes in Pezizomycotina. BMC Evolutionary Biology 2010, 10:68(in press)
Cheng-Gang Zou1, Hui-Hui Tu1, Xian-Yong Liu, Nan Tao, Wei Zhou, Ke-Qin Zhang*, 2010, PacC in the nematophagous fungus Clonostachys rosea controls
virulence to nematodes. Environmental Microbiology and Environmental Microbiology Reports.(accepted)
Li GH, Dang LZ, Hong LJ, Zheng LJ, Liu FF, Li L, Liu YJ, Zhang KQ*.2009. Nematicidal activity of honokiol and magnolol isolated from Magnolia tripetala. J Phytopathol 157: 390-392
Wang XB, Li GH, Zheng LJ, Ji KY, Lv H, Liu FF, Dang LZ, Mo MH, Zhang KQ*. 2009. Nematicidal cardenolides from Nerium indicum Mill. Chem Biodivers 6: 431-436
Li GH, Zheng LJ, Liu FF, Dang LZ, Li L, Huang R, Zhang KQ*.2009. New cyclopentenones from strain Trichoderma sp. YLF-3. Nat Prod Res 23: 1431-1435
Gong X, Yang J, Dong J, Zhe W, Li Q, Wang L, Duan Y, Zhang KQ*. 2009. Isolation and characterization of Rhodococcus sp. Y22, and its potential application in tobacco processing. Res Microbiol 160: 200-204
Gan ZW, Yang JK, Lou ZY, Zhang KQ*. 2009.Crystallization and Preliminary Crystallographic Analysis of a Chitinase from Clonostachys rosea. Acta Cryst. F65, 386-388.
Liu Y, Liu Y, Zhang KQ*. 2009. Nematicidal activity of Paecilomyces spp. and isolation of a novel active compound. J Microbiol 47：248-252.
Ding J, Huang X, Zhang L, Zhao N, Yang DM, Zhang KQ. 2009*. Tolerance and Stress Response to Ethanol in the Yeast Saccharomyces cerevisiae. Appl Microbiol Biotech 85:253-263
Zhang Y, Yu ZF, Baral HO, Mo MH, Zhang KQ*. 2009. New species and records of Orbilia (Orbiliaceae, Ascomycetes) from China. Fungal Divers 36:141-153
Yu Z, Kong Y, Zhang Y, Qiao M, Guo J, Zhang KQ*. 2009. A new Dactylella species from Orbilia alba. J Microbiol 47: 265-269
Wang L, Dong JY, Song HC, Shen KZ, Wang LM, Sun R, Wang CR, Gao YX, Li GH, Li L , Zhang KQ*. 2009.Three new naphthoquinone pigments isolated from the freshwater fungus, Astrosphaeriella papuana. Planta med 75: 1339-1343
Dong JY , Wang LM, Song HC, Shen KZ, Zhou YP, Wang L, Zhang KQ*. 2009. Colomitides A and B: novel ketals with an unusual 2,7-dioxabicyclo[3.2.1]octane ring system from the aquatic fungus YMF 1.01029. Chem Biodivers 6: 1216-1223
Dong JY, Song HC, Li JH, Wang CR, Sun R, Tang YS, Shen KZ, Wang L, Wang LM, Zhou YP, L Li, Zhang KQ* . 2009 Two unusual naphthalene-containing compounds from a freshwater fungus YMF 1.01029. Chem Biodivers 6(4): 569-77
Dong JY , Zhang KQ* .Ophiocerol, a novel macrocylic neolignan from the aquatic fungus Ophioceras dolichostomum YMF1.00988. Nat Prod Res 23: 1431-1435
Zou CG, Gao XY, Zhao YS, Li SD, Cao XZ, Zhang Y, Zhang KQ﹡. 2009. Homocysteine enhances cell proliferation in hepatic myofibroblastic stellate cells. J Mol Med 87:75- 84.
MH Mo, WM Chen, HR Yang, K-Q Zhang*. 2008, Diversity and metal tolerance of nematode-trapping fungi in Pb-polluted soils. J Microbiol 46: 16-22.
Z-F Li, C-S Zou, Y-Q He, M-H Mo, K-Q Zhnag*. 2008 ,Phylogenetic analysis on the bacteria producing non-volatile fungistatic substances. J Microbiol 46: 250-256
X Li, J Yang, X Li, W Gu, J Huang, K-Q Zhang﹡. 2008, Metabolism of ferulic acid via 4-vinylguaiacol to vanillin by a strain of Enterobacter sp. Px6-4 newly isolated from Vanilla root. Process Biochem 43: 1032-1037.
Y Luo, J Yang, M Zhu, J Yan, M Mo, W Zhou, and K-Q Zhang*. 2008, Characterization of Mutations in AlHK1 Gene from Alternaria longipes: Implication of Limited Function of Two-Component Histidine Kinase on Conferring Dicarboximide Resistance. J Microbiol Biotechnol 18:15-22
C Chen, X Li, J Yang, X Gong, K-Q Zhang﹡. 2008, Isolation of nicotine-degrading bacterium Pseudomonas sp. Nic22, and its potential application in tobacco. Int Biodeter Biodeg 62: 226-231.
J Li, J Yang, L Liang, KQ Zhang﹡. 2008. Taxonomic Revision of the Nematode-Trapping Fungus Arthrobotrys multisecundaria. J Microbiol 46: 513-518
L Zhang, J Yang, Q Niu, X Zhao, F Ye, L Liang, K-Q Zhang﹡. 2008, Investigation on the infection mechanism of the fungus Clonostachys rosea against nematodes using the green fluorescent protein. Appl Microbiol Biotechnol 78: 983-990
JK Yang, FP Ye, QL Mi, SQ Tang, J Li, K-Q Zhang﹡. 2008, Purification and cloning of an extracellular serine protease from the nematode-trapping fungus Monacrosporium cystosporium. J Microbiol Biotechnol 18: 852-858
GH Li, M Duan, ZF Yu, L Li, JY Dong, XB Wang, JW Guo, R Huang, M Wang, K-Q Zhang﹡. 2008, Stereumin A-E, sesquiterpenoids from the fungus Stereum sp. CCTCC AF 207024. Phytochemistry 69: 1439-1445
XB Wang, GH Li, L Li, LJ Zheng, R Huang, K-Q Zhang﹡. 2008, Nematicidal coumarins from Heracleum candicans Wall. Nat Prod Res 22: 666-71.
YJ Liu, Y. Liu, K-Q Zhang﹡. 2008, Xanthothone, a new nematicidal N-compound from Coprinus xanthothrix. Chem Nat Compd 44: 203-205.
JY Dong, HC Song, JH Li, YS Tang, R Sun, L Wang, YP Zhou, LM Wang, KZ Shen, CR Wang, K-Q Zhang﹡. 2008, Ymf 1029A-E, preussomerin analogues from the fresh-water-derived fungus YMF 1.01029. J Nat Prod 71: 952-6
Y Zhu, J Dong, L Wang, W Zhou, L Li, H He, H Liu, KQ Zhang﹡. 2008, Screening and isolation of antinematodal metabolites against Bursaphelenchus xylophilus produced by fungi. Ann Microbiol 58:375-380
L Wang, J Dong, HC Song, KZ Shen, L Mei Wang, R Sun, C Wang, G Li, L LI, K-Q Zhang﹡. 2008, Screening and isolation of antibacterial activities of the fermentative extracts of freshwater fungi from Yunnan Province, China. Ann Microbiol 58: 1-6
LH Guo, S Chen, K Liu, Y Liu, L Ni, K-Q Zhang, L Zhang﹡. 2008, Isolation of Heat Shock Factor HsfA1a-binding Sites in vivo Revealed Variations of Heat Shock Elements in Arabidopsis thaliana. Plant Cell Physiol 49: 1306 – 1315
Tian, B. Y., Yang, J. K., Lian, L. H., Wang, C. Y., Zhang, K. Q ﹡. 2007. Role of neutral protease from Brevibacillus laterosporus in pathogenesis of nematode. Applied Microbiology and biotechnology. 74: 372-380.
Jinkui Yang, Baoyu Tian, Lianming Liang and Ke-Qin Zhang﹡. 2007, Extracellular enzymes and the pathogenesis of nematophagous fungi. Appl. Microbio. Biotechnol. 75:21-31
Jinkui Yang, Lianming Liang, Ying Zhang, Juan Li, Lin Zhang, Fengping Ye, Zhongwei Can and Ke-Qin Zhang﹡. 2007, Purification and cloning of a novel serine protease from the nematode-trapping fungus Dactylellina varietas and its potential roles in infection against nematodes. Appl. Microbio. Biotechnol.75:557-565.
Jinkui Yang, Juan Li, Lianming Liang, Baoyu Tian, Ying Zhang & Ke-Qin Zhang﹡. 2007. Cloning and characterization of a cuticle-degrading protease from the nematode-trapping fungus Arthrobotrys conoides. Archives of Microbiology. 188:167-174..
Qiuhong Niu, Xiaowei Huang, Lin Zhang, Lihui Lian, Yunxia Li, Juan Li, Jinkui Yang and Ke-Qin Zhang﹡. 2007, Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida. Appl. Microbiol Biotechnol. 75：141-148
Jin-Yan Dong, Ye-Gao Chen, Hong-Chuan Song, Yan-Hui Zhu, Yong-Ping Zhou, Lei Li, Yan-Ping He, Jie Cao and Ke-Qin Zhang﹡. 2007, .Hydroxylation of the Triterpenoid Nigranoic Acid by the Fungus Gliocladium roseum YMF1.00133. Chemistry & Biodiversity 4: 112-117
Z.F.Yu, Y. Zhang, M.Qiao and K.Q. Zhang﹡. 2007, Orbilia dorsalia sp. Nov., the teleomorph of Dactylella dorsalia sp.nov. Cryptogamie, Mycologie 28(1): 55-63
Linjun Hong, Guohong Li, Wei Zhou, Xinbiao Wang and Ke-Qin Zhang﹡.2007, Screening and isolation of a nematicidal sesquiterpene from Magnoloa grandiflora L. Pest Manag Sci 63: 301-305
Hongyan Su, Yu`e Hao, Minghe Mo and Keqin Zhang﹡.2007, The ecology of nematode-trapping hyphomycetes in cattle dung from three plateau pastures. Veterinary parasitology. 144: 293-298.
Chao Lin, Jinkui Yang, Hui Sun, Xiaowei Huang, Rubin Wang and Ke-Qin Zhang﹡. 2007, Purification and characterization of a ß-1,3-glucanase from the novel mycoparasit Periconia byssoides. Biotechnol Lett 29: 617-622.
Lei Li, Minghe Mo, Qing Qu and Ke-Qin Zhang﹡. 2007, Compounds inhibitory nematophagous fungi produced by Bacillus sp. Strain H6 isolated from soil. European Journal of Plant Pathology.117: 329-340.
Hong Luo, Yajun Liu, Lin Fang, Xuan Li, Ninghua Tang and Ke-Qin Zhang﹡. 2007, Coprinus comatus Damages Nematode Cuticles Mechanically with Spiny Balls and Produces Potent Toxins to Immobilize Nematodes. Applied and Environmental Microbiology 73（12）：3916-3923
L.H. Lian, B.Y.Tian, R.Xiong, M.Z. Zhu, J. Xu and K.Q. Zhang﹡ 2007. Proteases from Bacillus: a new insight into the mechanism of action for rhizobacterial suppression of nematode. Letter in Applied Microbiology 45: 262-269.
Liu SQ., Meng ZH., Yang JK., Fu YX. Zhang KQ﹡. 2007. Characterizing structural features of cuticle-degrading proteases from fungi by molecular modeling. BMC: Structure Biology 7:1-33,
Tian, B. Y., Yang, J. K., Zhang, K. Q *. 2007. Bacteria used in biocontrol nematode: potential, development and perspective. FEMS Microbiology Ecology 61:197-213
Chun-Yan Wang, Xuan Li, Ming-He Mo and Ke-Qin Zhang﹡ 2007, Morphological characteristic and infection process of nematophagous Harposporium with species reference to two new species Fungal Diversity 26:287-304
Lin Qian DONG, Ming He Mo, Jin Kui YANG and Ke-Qin ZHANG﹡ 2007，A method for obtaining quantities of Caenorhabditis elegans eggs. Nematology 9(5):743-744.
Zou CS, MO MH, Zhang KQ﹡. 2007. Possible contributions of volatile-producing bacteria to soil fungistasis. Soil Biology & Biochemistry, 39:2371-2379
Ying-Qi Gu, Ming-He Mo, Jun-Pei Zhou, Chang-Song Zou, Ke-Qin Zhang﹡, 2007, Evaluation and identification of potential organic nematicidal volatiles from soil bacteria. Soil Biology & Biochemistry, 39: 2567-2575
Ying Zhang, Ze-Fen Yu, H.-O. Baral, Min Qiao1, Ke-Qin Zhang﹡ 2007, A new species of Orbiliaceae from Yunnan, China. Cryptogamie,Mycologie, 27(4):289-294
Ying Zhang, Ze-Fen Yu, H.-O. Baral, Min Qiao, Ke-Qin Zhang﹡ 2007, Pseudorbilia gen. nov.(Orbiliaceae) from Yunnan, China. Fungal Diversity 26: 1-7.
Jinyan Dong, Yanhui Zhu, Hongchuan Song, Ru Li, Hongping He, Haiyang Liu, Rong Huang, Yongping Zhou, Le Wang, Yi Cao and Keqin Zhang﹡.2007, Nematicidal Resorcylides from the Aquatic Fungus Caryospora callicarpa YMF1.01026. J. Chem. Ecol. ，33: 1115-1126
Guohong Li, Keqin Zhang﹡, Jiangping Xu, Jinyan Dong and Yajun Liu.2007, Nematicidal Substance from Fungi. Recent Patents on Biotechnology 1：212-233
Ze-Fen Yu, Min Qiao, Ying Zhang and Ke-Qin Zhang*. 2007， Two new species of Trichoderma from Yunnan, China. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology 92: 101-108
Guo-Hong Li, Ze-Fen Yu, Xuan Li, Xing-Biao Wang, Li-Jun Zheng and Ke-Qin Zhang* 2007, Nematicidal Metabolites Produced by the Endophytic Fungus Geotrichum sp.Chemistry & Biodiversity 4: 1520-1524.
Xiaowei Huang, Yunxia Li, Qiuhong Niu and Ke-Qin Zhang﹡ 2007, Suppression Subtractive Hybridization(SSH) and its modifications in microbiological research. Appl. Microbiol. Biotechnol. 76: 753-760.
Zhongwei Gan, Jinkui Yang, Nan Tao, Ze Fen Yu and Ke-Qin Zhang﹡ 2007, Cloning and Expression Analysis of a Chitinase Gene Crchil from the Mycoparasitic Fungus Clonostachys rosea(syn. Gliocladium roseum). The Journal of Microbiology45(5):1-9
Zhongwei Gan, Jinkui Yang, Nan Tao, Lianming Liang, Qili Mi, Juan Li and Ke-Qin Zhang﹡ 2007, Cloning of the gene Lecanicillium psalliotae chitinase Lpchi1 and identification of its potential role in the biocontrol of root-knot nematode Meloidogyne incognita. Appl. Microbiol. Biotechnol. 76: 1309-1317.
Linqian Dong, Minghe Mo, Jinkui Yang, Ke-Qin Zhang.2007.Cloning and phylogenetc analysis of the chitinase gen from the facultative pathogen Paecilomyces lilacinus. Journal of Applied Microbiology. 103:262-269
Hong Luo，Xuan Li，Guohong Li and Ke-Qin Zhang﹡ 2006, Acanthocytes on Stropharia rugosoannulata function as a nematode-attacking device. Applied and Environmental Microbiology 72（4）2982-2987