Whitehead Institute for Biomedical Research

Whitehead Institute for Biomedical Research

Robert T. Wheeler

Whitehead Institute for Biomedical Research

9 Cambridge Center

Cambridge, MA 02142

(617) 258-5232 (phone)

(617) 258-9872 (fax)

E-mail:

Education and Professional Experience:

2000-presentWhitehead InstituteCambridge, MA

Post-doctoral Fellow

Sponsor: Gerald R. Fink, PhD

1994-2000Stanford UniversityStanford, CA

PhD, Department of Developmental Biology

Advisor: Lucy Shapiro, PhD

Thesis Title: “Dynamic Localization of Bacterial Signaling Proteins Controlling

Differentiation and Cell Cycle Progression”

1993-1994University of MunichMunich, Germany

Research Assistant

Advisor: Diethard Tautz, PhD

1989-1993Harvard CollegeCambridge, MA

B. A. Biology, Magna Cum Laude

Honors Thesis Advisor: Daniel G. Jay, PhD

Honors, Fellowships, and Grants:

2006-presentMerck Inc. Investigator Initiated Studies Program Grant

2004-2006Charles A. King Trust Fellowship

2005Keystone Symposium Travel Grant (NIH/NIAID)“Innate Immunity to Pathogens”

2001-2004Burroughs Wellcome Fund Fellowship of the Life Sciences

Research Foundation

1994-1997National Science Foundation Pre-doctoral Fellowship

1993-1994Fulbright Fellowship

1991, 1992Ford Undergraduate Research Grants

Professional Experience:

Invited Speaker:

ThomasJeffersonUniversity, Dept. Microbiology and Immunology, April 2007

StanfordUniversity, Dept. Biological Sciences, March 2007

Northeastern University, Dept. Biology, February 2007

Seminar, Dept. Molecular and Cell Biology, BostonUniversityGoldmanSchool of Dentistry, 2002

Platform Presentations:

Candida and Candidiasis, March 2006

Keystone Symposium “Innate Immunity to Pathogens,” February 2005

International Workshop for Integrated Yeast Sciences, 2004

NE Regional Yeast Meeting, 2003

Poster Presentations:

Keystone Symposium, “Linking Innate with Adaptive Immune Responses,” 2003

Candida and Candidiasis, 2004

Yeast Genetics and Molecular Biology Meeting, 2002

ColdSpringHarbor Symposium “Microbial Pathogenesis & Host Response,” 2005

Peer Reviewer: Molecular Microbiology, Archives of Medical Research, European Cytokine Network

Service and Mentoring:

Whitehead Teacher Partner Program,invited seminar on Fungal Pathogenesis (2006)

Whitehead Board of Associates,invited presentation (2003)

Whitehead Post-doctoral Advisory Group,served (2001-2003)

Whitehead Library Advisory Group,served (2005)

MIT/Whitehead Post-doctoral Career Seminars,organized (2002-2003)

Whitehead High School Student Program, tour guide (2005-2006)

Direct supervisor of technical associate, Diana Kombe (9/2006-present)

Closely supervised PhD student, Joel Moxley (3/2004-1/2007)

Closely supervised an undergraduate, Rishi Puram (1/2005-5/2005)

Supervised several rotation students (both Fink Lab and Shapiro Lab)

Publications:

Johnnidis J.B., Harris M.H., Wheeler R.T., Stehling-Sun S., Lam M.H., Kirak O., Brummelkamp T.R., Fleming M.D. and Camargo F.D. (2008) Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature (in press).

Wheeler R.T., Fink G.R.(2006) A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog. Apr;2(4):e35. Epub 2006 Apr 28.

Wheeler, R. T., Kupiec, M., Magnelli, P., Abeijon, C. and Fink, G.R. (2003) A Saccharomycescerevisiae mutant with increased virulence.Proc Natl Acad Sci U S A. 100(5):2766-70.

Wheeler, R. T. and Shapiro, L. (1999) Differential localization of two histidine kinases controlling bacterial cell differentiation. Molecular Cell 4, 683-694

Wheeler, R. T., Gober, J. W. and Shapiro, L. (1998) Protein localization during the Caulobacter crescentus cell cycle. Curr. Opin. Microbiol. 6, 636-642.

Wheeler, R. T. and Shapiro, L. (1997) Bacterial Chromosome Segregation: Is There a Mitotic Apparatus? Cell 88, 577-579.

Winzeler, E., Wheeler, R. and Shapiro, L. (1997) Transcriptional analysis of the Caulobacter 4.5S RNA ffs gene and the physiological basis of an ffs mutant with a Ts phenotype. J. Mol. Biol. 272(5), 665-676.