Vth International Conference on Environmental Mutagens in Human Populations (Vth ICEMHP)

Theme: Identification of Environmental Hazards and Promotion of Health

May 20 - 24, 2007

Antalya, Turkey

Co-chairs: William W. Au, Semra Sardas and Ali Karakaya

Scientific Program

Day 1 (May 20th) Sunday
1400-1700 / Registration
1700-1730 / Opening Ceremony
1730-1810 / Keynote Lecture
Her Royal Highness Professor Dr. Princess Chulabhorn
Opportunities and challenges on environmental health in Southeast Asia.
President, Chulabhorn Research Institute, Bangkok, Thailand.
(Introduction by Semra Sardas).
1830-2030 / Welcome Reception
Day 2 (May 21th) Monday
830-910 / Keynote Speaker
Dr. William Suk
Strategies for Addressing Global Environmental Health Concerns.
Director, Center for Risk and Integrated Sciences and Director, Superfund Basic Research Program, National Institute of Environmental Health Sciences, RTP,
North Carolina. (Introduction by Ali Karakaya)
910-930 / Coffee Break
930-1200 / Symposium Session 1
Mechanisms of mutagenesis and carcinogenesis
Co-Chairs:
§  David DeMarini, National Institute of Environmental Health Sciences, USA.
§  Lucia Ribeiro, University of Sao Paolo, Brazil.
930-1000 / Lawrence Loeb: Generation of multiple mutations in cancer. University of Washington, Seattle, WA, USA.
1000-1030 / Alain Sarasin: Molecular mechanisms of sunlight-induced skin cancer. CNRS, Villejuif, France.
1030-1100 / Martina Viegl: DNA repair and instability in the development of colon cancer. Case Western Reserve University, Cleveland, OH, USA..
1100-1130 / Bernd Kaina: Genotoxic and apoptotic responses triggered by DNA alkylation damage. University of Mainz, Mainz, Germany.
1130-1200 / Eugenia Dogliotti: Mechanisms of oxidative DNA damage repair and relevance to human pathology. Istituto Superiore di Sanita, Rome, Italy.
1200-1300 / Lunch
1300-1530 / Symposium Session 2
Children Environmental Health
Co-Chairs:
§  Nina Holland, University of California, Berkeley, USA.
§  Wagida Anwar, Ain Shams University, Cairo, Egypt.
1300-1330 / Stefano Bonassi: Epidemiological study design in Children’s Studies. National Cancer Research Institute, Genoa, Italy.
1330-1400 / Chris Wild: Environmental exposures and child health in developing countries: the example of aflatoxin. Leeds University, England.
1400-1430 / Alexandra Fucic: Genetic toxicity in children after exposure in radiochemical environment. Institute of Medical Research and Occupational Health, Croatia.
1430-1500 / Semra Sardas: Assessment of DNA damage in child workers in small workshops in Turkey. Marmara University, Istanbul, Turkey.
1500-1530 / Nina Holland: Genetic and Immunological Biomarkers in Children. University of California, Berkeley, California, USA.
1530-1550 / Coffee Break
1550-1820 / Symposium Session 3
Human monitoring for health risk evaluation and disease prevention
Co-Chairs:
§  Silvio De Flora, University of Genoa, Genoa, Italy.
§  Mathuros Ruchirawat, Princess Chulabhorn Research Institute, Bangkok, Thailand.
1550-1620 / Peter Farmer: Use of biomarkers to identify health risk from exposure to hazardous environmental pollutants. Cancer Biomarkers and Prevention Group, Leicester, United Kingdom.
1620-1650 / Albrecht Seidel: Determination of urinary chemical metabolites for assessment of exposure of the general population to environmental toxic PAH. Biochemical Institute for Environmental Carcinogens. Grosshansdorf, Germany.
1650-1720 / Silvio De Flora: Threshold mechanisms in chromium(VI) genotoxicity and carcinogenicity. University of Genoa, Genoa, Italy.
1720-1750 / Ilse Decordier: On comparison of repair capacities in mothers and new-born daughters. Vrije Universiteit Brussel, Brussels, Belgium.
1750-1820 / Young-Joon Surh: Inflammation-associated cancer and its chemoprevention. Seoul National University, Korea.
1900-2030 / Dinner
2030-2230 / Workshop 1
HUMN project workshop on the buccal micronucleus assay
Michael Fenech, Stafano Bonassi, Nina Holland
a)  Discuss current state of knowledge on the buccal micronucleus assay.
b)  Identify important gaps of knowledge regarding theory, biology and methods.
c)  Decide on the appropriate plan of action to resolve the key methodological and knowledge gap issues.
d)  Explore possibility of pooling data bases to determine most important variables affecting the assay.
Day 3 (May 22nd) Thuesday
830-910 / Keynote Speaker
Dr. Henry Falk
Improvement of public health, a national and international priority.
Director, Coordinating Center for Environmental Health and Injury Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
(Introduction by William W. Au)
ICEM2009, Florence, Italy, announcement by Dr. Silvio DeFlora
910-930 / Coffee Break
930-1200 / Symposium Session 4
Gene-Environmental interactions on health
(Sponsored by the National Institute of Environmental Health Sciences)
Co-Chairs:
§  Douglas Bell, NIEHS, Research Triangle Park, NC, USA.
§  Hannu Norppa, Finnish Institute of Occupational Health, Helsinki, Finland.
930-1000 / Peter Stambrook: Cellular mechanisms for preserving genomic integrity. University of Cincinnati, Cincinnati, Ohio, USA.
1000-1030 / Stefano Bonassi: Susceptibility and susceptible populations in environmental health - SNP’s, haplotypes, and exposure to asbestos in the etiology of respiratory tract cancers. National Cancer Research Institute, Genoa, Italy.
1030-1100 / Hannu Norppa: Relationship between susceptibility, cytogenetic biomarkers and risk for development of cancer. Finnish Institute of Occupational Health, Helsinki, Finland.
1100-1130 / Douglas Bell: Discovery and functional analysis of variation in human damage response pathways. National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
1130-1200 / Tom Kensler: Protection against cell injury and health effects from environmental toxic substances. Johns Hopkins University, Baltimore, MD, USA.
1200-1300 / Lunch
1300-1530 / Symposium Session 5
Translation of scientific knowledge into public health practices
(Sponsored by the Joint Centers for Environmental Health and Injury Prevention, Centers for Disease Control and Prevention)
Co-Chairs:
§  Christopher DeRosa, ATSDR, Atlanta, GA, USA.
§  Rakhmet Bersimbaev, Kazakh National University, Almaty, Kazakhstan.
1300-1330 / Henry Falk: Good science makes good decisions. Coordinating Center for Environmental Health and Injury Prevention, Atlanta, Georgia, USA.
1330-1400 / Pamela Meyer: Global approach to reducing lead exposure and poisoning. ATSDR, Atlanta, GA, USA.
1400-1430 / Christopher DeRosa: Human health research and policy development – fish consumption and exposure to toxic substances. ATSDR, Atlanta, Georgia, USA.
1430-1500 / Takehiko Nohmi: DNA Lesions and Repair – Asbestos and Other Environmental Toxic Chemicals. National Institute of Health Sciences, Tokyo, Japan.
1500-1530 / Arthur Frank: Prevention of exposure to hazardous substances - social and ethical issues. Drexel University, Philadelphia, PA, USA.
1530-1550 / Coffee Break
1550-1750 / Poster Session 1
1900-2030 / Dinner
2030-2200 / Workshop 2
Community outreach and health promotion
(National Center for Environmental Health, and Agency for Toxic Substances and Disease Registry)
Day 4 (May 23th) Wednesday
830-910 / Keynote Speaker
Dr. James Gentile
Education and training for future research biologists.
President, Research Corporation, Tucson, Arizona.
(Introduction by Lucia Ribeiro)
910-930 / Coffee Break
930-1200 / Symposium Session 6
New technologies and frontiers in environmental health
Co-Chairs:
§  Hikoya Hayatsu, Shijitsu University, Okayama, Japan.
§  Malyn Chulasiri, Mahidol University, Bangkok, Thailand.
930-1000 / Hikoya Hayatsu: New technologies and concepts in genetic toxicology. Shijitsu Univ., Okayama, Japan.
1000-1030 / Hiroshi Kasai: 4-Oxo-2-hexenal, a mutagen formed by ω-3 fat peroxidation: occurrence, detection and adduct formation. University Occupational and Environmental Health, Kitakyushu, Japan.
1030-1100 / Leona Samson: Genomic approaches for gene expression that is indicative of human exposure to environmental toxic substances. Massachusetts Institute of Technology, Boston, USA.
1100-1130 / David DeMarini: Germline mutation, DNA damage and epigenetic modification in response to exposure to particulate air pollution. US Environmental Protection Agency.
1130-1200 / Jurgen Borlak: The next innovation cycle in toxicogenomics. Frauenhofer Institute of Toxicol. Environ. Med., Germany.
1200-1300 / Lunch
1300-1530 / Symposium Session 7
Unique environmental health concerns and consequences
Co-Chairs:
§  Ali Karakaya, Gazi University, Ankara, Turkey.
§  Kei Nakachi, Radiation Effect Res. Foundation, Hiroshima, Japan.
1300-1330 / Rakhmetkaji Bersimbaev: Cold war legacy health effects from nuclear tests in Kazakhstan. Al-Farabi Kazakhstan National University, National University, Almaty, Kazakhstan.
1330-1400 / Kei Nakachi: Hiroshima 60 Years: Monitoring of Survivors. Radiation Effect Res. Foundation, Hiroshima, Japan.
1400-1430 / Myron Mehlman: Benzene – a multipotential carcinogen. University of Texas Medical Branch, Galveston, Texas, USA.
1430-1500 / Zdenko Herceg: Epigenetic events induced by environmental factors for the development of cancer in populations. International Agency for Research on Cancer, Lyon, France.
1500-1530 / Ashok Giri: Arsenic-induced health problems in India – involvement of genetic susceptibility and chromosome aberrations. Kolkata, India.
1530-1550 / Coffee Break
1550-1750 / Poster Session 2
1900-2030 / Dinner
2030-2200 / Workshop 3
Use of biomarkers in toxicology and population monitoring
(Sponsored by the Novartis Pharmaceutical Company)
§  David DeMarini: Mutagenic basis of biomarkers and their relationship to carcinogenesis. US Environmental Protection Agency, Research Triangle Park, NC.
§  Azeddine Elhajouji: Use of biomarkers for genotoxicity screening in the drug industry. Novartis Pharma AG, Basel, Switzerland.
§  William Au: Biomarker monitoring of populations for exposure to mutagenic substances and for risk assessment. The University of Texas Medical Branch, Galveston, TX.
Day 5 (May 24th) Thursday
900-1130 / Symposium Session 8
Environmental mutagens and health risks in Turkey
(Sponsored by the Turkey Society of Toxicology)
Co-Chairs:
§  Sema Burgaz, Turkish Society of Toxicology, Turkey.
§  Bensu Karahalil, Gazi University, Ankara, Turkey.
900-930 / Salih Emri: Gene-environment interactions in the pathogenesis of malignant mesothelioma patients from Cappadocia region of Turkey. Hacettepe University, Ankara, Turkey.
930-1000 / Nursen Basaran: Risk of genotoxicity by occupational crystalline silica exposure in Turkey. Hacettepe University, Ankara, Turkey.
1000-1030 / A. Murat Tuncer: Environmental Effect on Child Health in Turkey. Cancer Control Department, Ministry of Health, Turkey.
1030-1045 / İlker Ates: The Effects of Mutations in TNF-α and IL-1 Genes on the Levels of These Cytokines Released From Blood Monocytes. Ankara University, Ankara, Turkey.
1045-1100 / Gonca Cakmak Demircigil: DNA Effect Biomarkers for Crystalline Silica Containing Dust Exposed Workers in Turkey. Gazi University, Ankara, Turkey.
1100-1115 / To be selected from abstracts..
1130-1230 / Lunch
1230-1500 / Symposium Session 9
Transplacental and transgenerational exposures and health consequences
Co-Chairs:
§  Taisei Nomura, Osaka University, Osaka, Japan.
§  Radim Sram, Institute of Experimental Medicine, Prague, Czech Republic.
1230-1300 / Radim Sram: Air pollution and risk for human disease and reproductive problems. Institute of Experimental Medicine, Prague, Czech Republic.
1300-1330 / David Sedwick: Epigenetic and imprinting problems as causes for developmental abnormalities and adult disease. Case Western University, Cleveland, Ohio, USA.
1330-1400 / Silvio De Flora: Birth related genomic changes and neonatal carcinogenesis. University of Genoa, Genoa, Italy.
1400-1430 / Michael Wilhelm: The Duisburg birth cohort study: Influence of the prenatal exposure to PCDD/Fs and dioxin like PCBs on thyroid hormones in newborns and neurodevelopment of infants. Abteilung Hygiene, Sozial- umd Umweltmedizin, Bochum, Germany.
1430-1500 / Taisei Nomura: Transgenerational effects from exposure to environmental toxic substances. Osaka University, Osaka, Japan.
1500-1520 / Coffee Break
1520-1650 / Symposium Session 10
Building environmental health infrastructure through science, education and outreach effort
(Sponsored by Research Corporation)
Co-Chairs:
§  James Gentile, Research Corporation, Arizona, USA.
§  Robert Johnson, University of Texas Medical Branch, Galveston, TX, USA.
1520-1550 / James Gentile: Opportunities and challenges in developing future biomedical scientists. Research Corporation, Arizona, USA.
1550-1620 / Robert Johnson: Environmental health training in international medical specialists. University of Texas Medical Branch, Galveston, TX, USA.
1620-1650 / Diana Anderson: The WHO/ICPS guidelines for Human Monitoring. University of Bradford, United Kingdom
2000-2330 / GALA DINNER
and
Poster award presentations and remarks
Day 6 (May 25th) Friday
Departure or Tours

* Presentations:

Each keynote presentation is 40 minutes

Each symposium session has 5 speakers: 25 minutes talk and 5 minutes discussion for each speaker.

Each workshop session has 1.5 hours for presentations and discussions.