Principal Investigator/Program Director (Last, First, Middle):

FACILITIES AND OTHER RESOURCES(correct title)

(title used to be RESOURCES)

INSTRUCTIONS

NOTE: The following subsections are new!! Tailor them according to your grant. The blurbs in this document (below instructions) are provided to help you fold in the blurbs that are highly relevant to your proposal.

The Facilities and Other Resources section has been changed to require a description of how the scientific environment will contribute to the probability of success of the project, unique features of the environment, and for Early Stage Investigators, the institutional investment in the success of the investigator (e.g., resources, classes, etc.).

  1. ENVIRONMENTAL CONTRIBUTION TO PROBABILITY OF PROPOSED PROJECT SUCCESS

• Describe how the scientific environment in which the research will be done contributes to the probability of success (e.g., institutional support, physical resources, and intellectual rapport). In describing the scientific environment in which the work will be done, discuss ways in which the proposed studies will benefit from unique features of the scientific environment or subject populations or will employ useful collaborative arrangements.This information is used to assess the capability of the organizational resources available to perform the effort proposed.

• Identify the facilities to be used (laboratory, clinical, animal, computer, office, other). If appropriate, indicate their capacities, pertinent capabilities, relative proximity and extent of availability to the project. Describe only those resources that are directly applicable to the proposed work. Provide any information describing the Other Resources available to the project (e.g., machine shop, electronic shop) and the extent to which they would be available to the project.

  1. UNIQUE FEATURES OF THE ENVIRONMENT

Facilities & Other Resources

This information is used to assess the capability of the organizational resources available to perform the effort proposed. Identify the facilities to be used (Laboratory, Animal, Computer, Office, Clinical and Other). If appropriate, indicate their capacities, pertinent capabilities, relative proximity and extent of availability to the project. Describe only those resources that are directly applicable to the proposed work. Provide any information describing the Other Resources available to the project (e.g., machine shop, electronic shop) and the extent to which they would be available to the project. Please click the add attachment button to the right of this field to complete this entry.

  1. INSTITUTIONAL INVESTMENT IN SUCCESS OF INVESTIGATOR (e.g., resources, classrooms, etc.)

• For Early Stage Investigators, describe institutional investment in the success of the investigator, e.g., resources for classes, travel, training; collegial support such as career enrichment programs, assistance and guidance in the supervision of trainees involved with the ESIs project, and availability of organized peer groups; logistical support such as administrative management and oversight and best practices training; and financial support such as protected time for research with salary support.

*The Facilities and Other Resources section ispart of the R&R Other Project Information in the SF 424 (R&R) application,and part of the Resources Format Page in the paper PHS 398 application.

Note: #3 refers to Early Stage investigators only (see NIH definition below):

Definition of New Investigator(retrieved verbatim on 11-6-09, from:

In general, a Program Director/Principal Investigator (PD/PI) is considered a New Investigator if he/she has not previously competed successfully as PD/PI for a significant NIH independent research award. Specifically, a PD/PI is identified as a New Investigator if he/she has not previously competed successfully for an NIH-supported research project otherthan the following small or early stage research awards:

  • Pathway to Independence Award-Research Phase (R00)
  • Small Grant (R03)
  • Academic Research Enhancement Award (R15)
  • Exploratory/Developmental Grant (R21)
  • Clinical Trial Planning Grant (R34)
  • Dissertation Award (R36)
  • Small Business Technology Transfer Grant-Phase I (R41)
  • Small Business Innovation Research Grant-Phase I (R43)
  • Shannon Award (R55)
  • NIH High Priority, Short-Term Project Award (R56)
  • Competitive Research Pilot Projects (SC2, SC3)

Training-Related and Mentored Career Awards

  • All Fellowships (F awards)
  • All career awards (K awards)
  • Loan repayment contracts (L30, L32, L40, L50, L60)

Instrumentation, Construction, Education, Health Disparity Endowment Grants, or Meeting Awards

  • G07, G08, G11, G13, G20
  • S10, S15, S21, S22

Note regarding grants with Multiple PD/PIs: In the case of a grant application that involves more than one PI, all PD/PIs must meet the definition of New Investigator to check “Yes” in the “New Investigator” box.

Frequently Asked Questions about NIH New and Early Stage Investigator Policies

Blurbs on the following pages were updated November 2010.

NOTE: You will want to shorten many of the following sections, including onlythe most relevant information regarding your proposal.

ENVIRONMENTAL CONTRIBUTION TO PROBABILITY OF PROPOSED PROJECT SUCCESS

University of Florida (UF)(shorten/tailor)

The University of Florida is a fully accredited member of the Association of American Universities (AAU), comprised of the top 62 public and private institutions in North America. With approximately 50,000 students, UF is Florida’s oldest, largest, and most comprehensive university, ranked 7th largest in the nation. UF offers more degree programs on a single campus than all but two other US institutions, with 21 colleges and schools offering more than 100 majors and 52 undergraduate degree programs, including an institute of agricultural sciences and an academic health science center. It has also been designated by the Florida Board of Regents as one of four institutions in Florida focusing on graduate education and research.One of the nation’s leading research institutions, UF has a long history of established programs in research and service. The graduate school coordinates 123 master and 94 doctoral programs, for a total of 13,000 graduate students. UF received over$574 million in 2008-09 in externally-funded research, and a distinguished faculty of 3,600 received over 6,200 new awards, continuations and supplements. UF ranks 26th among all universities and 13th among public universities in total research expenditures.

UF Health Sciences Center (HSC)(shorten/tailor)

The HSC, enrolling over 6,000 students each year, is the most comprehensive academic health center in the southeastern US. Dedicated to rigorous programs of education, research, patient care and public service, its research enterprises were funded with over $289 million in 2009, accounting for50% of the university’s total research income. HSC faculty members are known nationally and internationally for research and clinical programs related to the brain and spine, cancer, genetics, diabetes, drug design and organ transplantation. Strong multidisciplinary, campus-wide programs are being developed in the areas of aging and children’s health. The HSC encompasses the colleges of Medicine, Nursing, Dentistry, Public Health and Health Professions, Pharmacy, and Veterinary Medicine, as well as the Veterinary Medicine Teaching Hospital (and an academic campus in Jacksonville offering graduate education programs in dentistry, medicine, nursing, and pharmacy). The HSC serves Florida through satellite medical, dental, and nursing clinics staffed by UF health professionals, and through affiliations with community-based health care facilities stretching from Miami to the Florida Panhandle. The HSC also provides continuing education programs for health professionals statewide.

Clinical and Translational Science Institute (CTSI)

In July 2009, UF received a $26 million dollar Clinical and Translational Science Award from National Institutes of Health. In winning the competitive award, UF joined a prestigious national consortium of research institutions, whose membership will be capped at 60 by 2012. The only university in Florida to receive the award, UF’s CTSI is dedicated to improving human health by accelerating the translation of basic research into new clinical treatments as quickly as possible.Specifically, goals are geared toward accelerating scientific discovery, enhancing patient care, producing highly skilled scientists and practitioners, and fostering partnerships with industry.

TAILOR THIS SECTION: The PI will receive full access to abroad continuum of CTSI resources foraccomplishing the proposed research (see Letter of support).CTSI resources span development and application of new basic science and clinical and community-based methods, including effective use of biomedical informatics and complex statistical analysis tools. Methodologists at UF have expertise in a wide range of areas, including biostatistics, epidemiology, and health services research. Their availability from different colleges provides intellectual diversity and a strong foundation for the CTSI Research Design and Analysis Program (RDAP), which will become the single point of reference to (1) facilitate multi- and interdisciplinary clinical and translational trials (CTS), (2) provide a robust training portfolio of basic/advanced graduate courses and short courses in research design, data acquisition and management, and analysis concepts and techniques, performed across the CTS research continuum from preclinical to community engagement, and (3) develop and adopt new methodology needed for clinical and translational research study design and analysis.Particular emphasis will be placed on mentoring junior CTS research methodologists, conducting methods research related to appropriate sample size and efficient study design, and conducting methods research that supports the functions of other cores. In addition to the CTSI RDAPcore, which contributes directly to Dr. Yoon’s (PI) research support, the regulatory Knowledge and Research Support (RKRS) core and Clinical Research Units (CRU/GCRC) will be available to PI. The goals of RKRS core are increased accessibility of information, provision of expert assistance (e.g., IND process for the FDA approval), assurance of rapid protocol activation, and maintenance of high scientific standards, ethical integrity, and access to the web-based application of electronic data capture system (REDCap).

In July 2009, UF received a $26 million dollar Clinical and Translational Science Award from National Institutes of Health. In winning the competitive award, UF joins a prestigious national consortium of research institutions, whose membership will be capped at 60 by 2012. UF is the only university in Florida to receive the award, which will be geared toward accelerating scientific discovery, enhancing patient care, producing highly skilled scientists and practitioners, and fostering partnerships with industry. With tremendous potential to support multi- and interdisciplinary research and to enrich education of an enormous pool of outstanding investigators and trainees at the University of Florida, the CTSI will provide enhanced infrastructure in biostatics, regulatory support, training, novel methodologies, and multidisciplinary opportunities. The impact of the CTSI will extend beyond academia to industry, government and the nation. In addition, discoveries that are developed commercially can generate royalty streams for the university.

Technological Access and Support in the HSC

PI Access and Software. PI computers are connected to networks and have remote access to the server and shared drives. The entire HealthScienceCenter complex has high-speed, wireless internet throughout. Site licenses are available for a full array of software, including SPSS and Microsoft Office. PIs have access to at least 146GB of memory via the network, and system support includes 24-hour access to consulting/technical services through UF’s Information Technology (IT) Center. The IT Center provides services to ensure informed and efficient use of information technology resources. The Customer Supportteam provides a single point of contact for all services, including desktop support. Information Management develops and maintains data-rich systems in support of enterprise applications. Systems Administration provides central networkoperating systems support, including e-mail, file sharing, security systems and data backup.Additional services include virus protection, desktop operating system integration, and web and database hosting.

Statistical Support in the HSC (GENERAL BLURBS)

Clinical Translational Science Institute (CTSI).The research supported at UF spans a widerange of disciplines and involves the development and application of new basic science, clinical and community-based methods, including effective use of biomedical informatics and complex statistical analysis tools. Methodologists at UF have expertise in a wide range of areas, including biostatistics, epidemiology, and health services research. The availability of methodologists in different colleges provides intellectual diversity and a strong foundation for the CTSI Research Design and Analysis Program (RDAP), which will become the single point of reference to (1) facilitate multi- and interdisciplinary clinical and translational trials (CTS), (2) provide a robust training portfolio of basic and advanced graduate courses and short courses in research design, data acquisition and management and analysis concepts and techniques performed across the CTS research continuum from preclinical to community engagement, and (3) develop and adopt new methodology needed for clinical and translational research study design and analysis.Particular emphasis will be placed on mentoring junior CTS research methodologists, conducting methods research related to appropriate sample size and efficient study design, and conducting methods research that supports the functions of other cores. These include techniques to analyze imaging data and the use of item response theory to improve measurement of health outcomes across different genders and racial and ethnic groups.

Research Data Coordinating Center (RDCC).The department of Epidemiology and Health Policy Research houses the RDCC, which serves as a core research facility, providing scientific services related to clinical database design and management. The RDCC offers the following services: 1) secure, high availability, web-based research data collection, 2) data collection, storage, and analysis, 3) review of scientific protocols to develop appropriate data management strategies, 4) form design for web-based and other data capture, 5) database design, 6) quality management and testing of data, 7) medical coding, 8) data entry and cleaning, 9) SQL queries, and 10) hosting web applications.

Division of Biostatistics. In addition to housing the RDCC, the department of Epidemiology and Health Policy Research also houses the Division of Biostatistics, which owns a network of more than 70 UNIX workstations that operate a rich library of software. Faculty here have broad expertise in methodological research, including: clinical trials and epidemiology, study design, survey methodology, decision theory, generalized linear models, longitudinal data analysis, survival analysis, structural equation models, and diagnostic testing. The Division of Biostatistics provides statistical support for sponsored research in genetics, aging, cancer, imaging, cardiovascular disease, dentistry, nursing, health services research, human development, and pharmaceutical research. It is also home to the Research and Biostatistics Consulting Lab, a fee-based consulting service related to optimal development of research design, measurement, and analytic strategies; statistical analyses; and methodological/statistical review of manuscripts.

HSC Library (HSCL)

The College of Nursing is co-located with the UF Health Science Center Library (HSCL), comprised of the main library in the Health Science Center, the Veterinary Medicine Reading Room, and the Borland Library in Jacksonville. The HSCL, containing the largest collection of health science reference material in the Southeast (over 3.3 million books and periodicals), ranks among the top 10 of 123 health research libraries nationally. A full range of computer-based bibliographic search services are available, and books and articles may readily be requested from other libraries through the interlibrary loan system. HSCL primary users include the faculty, students and staff of the six colleges (Medicine, Nursing, Dentistry, Public Health and Health Professions, Pharmacy, and Veterinary Medicine) of the HealthScienceCenter.

Biomedical Media Services in the HSCL. Housed in the HSCL, investigators have full access to services including photography, slide production, video development, graphics, and related production assistance.

UF COLLEGE OF NURSING (CON)

The College of Nursing, celebrating its 50th anniversary in 2006, is recognized nationally and internationally for innovative education, dynamic programs of research, and creative approaches to practice. As Florida’s flagship nursing school, Dean Kathleen Long, PhD, RNCS, FAAN, with three associate deans and one urban campus director (Jacksonville branch), administers the operations of the College. Approximately 70 faculty members, the majority of whom are prepared at the doctoral level, are involved in regional/national research and in practice throughout the state. There are also many expert clinicians holding national certifications. Research foci include aging and health, women’s health, health policy, and biobehavioral research.

The CON graduates the largest number of baccalaureate-prepared RNs in the state and is consistently ranked in the top ten percent of all baccalaureate and graduate degree-awarding nursing schools in the nation. One of six professional colleges within the UF Health Science Center in Gainesville, Florida, the CON also provides urban access for graduate students at UF’s Jacksonville campus. Since the establishment of the first Florida graduate program in nursing (1963), the CON has maintained a leadership role in graduate nursing education in the South: first nurse practitioner program in Florida, first BSN-to-PhD track in Florida, the Clinical Nurse Leader master’s degree track and the Doctor of Nursing Practice program, including one of the first BSN to DNP programs in the state and the country. The CON also offers, in conjunction with the University of Florida Graduate School, a Doctor of Philosophy (PhD) degree, with a major in nursing. CON enrollment currently consists of approximately 317 undergraduate students andgraduate students in three departments Adult and Elderly Nursing; Health Care Environments and Systems; and Women's, Children's and Family Nursing. All CON programs are State Board approved and/or nationally accredited.

Nursing students have an opportunity to learn and work with students from other Health Science Center colleges in collaborative health-care teams. The College maintains and participates in nursing and interdisciplinary clinics for women, children, adults, and elders in a variety of settings, with special emphasis on medically underserved and rural areas. Students have access to a fully integrated system of community hospitals and clinics, statewide home health care, and quaternary care at Shands Hospital.