Title: The Effect and Comparison between methods of weight loss
onadipokines and osteocalcin in obese patients
Name: Mohammed Albadah
King khalid university hospital ,Riyadh, Saudi Arabia
Objectives:
- Aim of this study is to determine the effect of weight loss in response to diet and life style modifications on the circulating levels of adipokines and osteocalcin.
- Analyze differences in biochemical markers before and after weight reduction.
Biochemical profiling: Lipid profile, LFT, CRP and Vit D levels, adipokines, and osteocalcin
Methods
A total of 57 adult obese patients (20-50 years of age, mean age 32.3 ± 8.7 years, BMI ›30) attending nutrition clinics at King Khalid university hospital , Riyadh were followed for four months. A food frequency questionnaire was filled up, their medical history and anthropometric measurements recorded and blood was drawn. Biochemical analyses were done by immunoassays using commercially available kits. Statistical Analyses: All analyses were performed using SPSS software, version 20
Result :
Subjects had lost significant weight with the dietary intervention (BMI 39.72 ± 7.58 pre-intervention vs. 37.83 ± 7.61 kg/m2 post-intervention, P=0.000). There was significant reduction following weight loss in waist circumference, total cholesterol, LDL-cholesterol, fasting blood glucose, HOMA-IR, bone specific alkaline phosphatase, and serum resistin levels. On the other hand, serum adiponectin levels had increased significantly following weight loss. There was no significant changes in the levels of CRP, HDL-cholesterol, triglycerides, vitamin D, total, carboxylated, and undercarboxylatedosteocalcin, and undercarboxylated to total osteocalcin ratio.
Conclusion
- Weight loss causes a significant increase in osteocalcin levels and decrease in adipokine levels and other hormonal changes.
- Combination of diet and exercise has a greater impact on weight reduction compared to either one alone
Further studies are needed with inclusion of women.
Biography
MOHAMMED SULAIMAN ALBADAH
Clinical Dietitian, King Khalid University Hospital
PERSONAL DATA
Date of Birth:August 10, 1972
Civil Status:Married
Gender:Male
Nationality:Saudi
Language :English and Arabic
Address:P.O. Box 245048 Riyadh 11312
Kingdom of Saudi Arabia
Contact Nos.:Mobile (+966) 505 256193
EmailAddress:
EDUCATION
Bachelor Degree in Applied Medical Science , Major in Community Health Nutrition ,King Saud University 1991 – 1996
Master Degree in Applied Medical Science , Major in Community Health clinical Nutrition ,King Saud University 2011-2014
SKILLS & COMPETENCIES
- Fluent in English, writing or spoken, in addition to the native Arabic language
- Computer literate, proficient in using computer software such as Windows XP and Microsoft Office
TRAINING & EXPERIENCE
- A year of internship moving between several hospitals (University Hospital, Security Forces Hospital – Riyadh, Prince Salman Hospital), 1997
- Winner of the Ideal Employee Prize from King Khalid University Hospital, 2002
- Member of Riyadh Diabetes Club.
- Participation in Nutritionist Employment Committee at King Khalid University Hospital, 2006 – 2008, 2009 , 2010&2011.
- Member of Saudi Commission for Health Specialties.
- Member the board of Saudi dietetic association since 2012.
- Attendance and participation in a number of different exhibitions and seminars in the field of Nutrition, including:
- Attendance of Nutrition Updates Course in Egypt, 2010
- Attendance of Nutrition Updates Course in Egypt, 2009
- Attendance of European Council Session on Nutrition ESPEN 30 in Italy, 2009
- Participation in the preparation of Wheat Allergy (Celiac Disease) Exhibition at King Khalid University Hospital, 2008
- Participation in the preparation of food exhibit in Ramadan, organized by King Khalid University Hospital for the year 2008
- Attendance of European Council Session on Nutrition ESPEN 28 in Istanbul, 2007
- English Course offered by Direct English Institute, 2007
- Participation in the preparation of the Eight Day Gallery of Diabetes organized by the Diabetes Center at King Abdul-Aziz University Hospital, 2004
- Participation in the preparation of Respiratory Disease Exhibition organized by King Khalid University Hospital, 2002
- Attendance of Food Safety Conference in Dammam, 2001
- Participation in a workshop on the feeding of the elderly at Prince Salman Social Council, 2000
- Attendance of Short Course in the Medical Terminology at the Security Forces Hospital in Riyadh, 1997
- Attendance of Spring Clinical Meeting forNational Kidney Foundation in lasVegas , 2011.
- Participation in poster presentation at ICE/ENDO 2014, June 21-24 in Chicago, Illinois.
- Attendance of Spring Clinical Meeting forNational Kidney Foundation in lasVegas , 2014.
In addition to many of the courses and certificates of thanks