Tables to consider for online publication

Table 5 Lymphatic mapping success rates of 692 patients with locally recurrent breast cancer stratified according to previous axillary procedure

Author / Year / N / Axillary procedure
ALND / LM successful
SNB / ALND / None / SNB / ALND / None / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Sood2 / 2004 / 3 / 0 / 3 / 0 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 0 / 2 / 0 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 2 / 14 / 0 / 2 / 9 / 0 / 11
Tada5 / 2005 / 3 / 0 / 2 / 1 / 1 / 0 / 1 / 2
Boughey6 / 2006 / 21 / 5 / 12 / 4 / NR / NR / NR / 10
Jackson7 / 2006 / 1 / 1 / 0 / 0 / 1 / 0 / 0 / 1
Newman8 / 2006 / 10 / 1 / 7 / 2 / 0 / 7 / 1 / 8
Roumen9 / 2006 / 12 / 2 / 10 / 0 / 2 / 8 / 0 / 10
Taback10 / 2006 / 15 / 6 / 9 / 0 / 5 / 6 / 0 / 11
Barone11 / 2007 / 19 / 7 / 12 / 0 / NR / NR / NR / NR
Intra12 / 2007 / 65 / 65 / 0 / 0 / 63 / 0 / 0 / 63
Port13 / 2007 / 117 / 54 / 63 / 0 / NR / NR / NR / 63
Axelsson14 / 2008 / 47 / 1 / 43 / 3 / NR / NR / NR / 24
Cox15 / 2008 / 56 / 56 / 0 / 0 / NR / NR / NR / NR
Karam16 / 2008 / 20 / 4 / 11 / 5 / 4 / 7 / 4 / 15
Koizumi17 / 2008 / 31 / 3 / 16 / 12 / 3 / 14 / 12 / 29
Schrenk18 / 2008 / 30 / 15 / 13 / 2 / 12 / 5 / 2 / 19
Tasevski19 / 2009 / 18 / 3 / 15 / 0 / 1 / 11 / 0 / 12
Van der Ploeg20 / 2010 / 48 / 36 / 12 / 0 / 26 / 6 / 0 / 32
Vicente21 / 2010 / 1 / 0 / 0 / 1 / 0 / 0 / 1 / 1
Yamashita22 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 0 / 45 / 0 / 0 / 11 / 0 / 11
Maaskant-Braat25 / 2011 / 109 / 40 / 69 / 0 / 28 / 47 / 0 / 75
Total
Total-NR
Total-NR
(LM performed)
Percentage (%)
95% CI / 692 / 301
692
43.5 / 361
692
52.2 / 30
692
4.3 / 148
179
82.7
76.2-87.8 / 139
197
70.6
63.6-76.7 / 21
22
95.5
75.1-99.8 / 405
572
70.8
66.9-74.5

N: Number; LM: Lymphatic mapping; SNB: Sentinel node biopsy; ALND: Axillary lymph node dissection; NR: Not recorded; CI: Confidence interval

Table 6 Lymphatic mapping success rates of 636 patients with locally recurrent breast cancer stratified according to previous breast treatment

Author / Year / N / Breast treatment / LM successful
BCT/Lump / Mast / BCT/Lump / Mast / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 1 / 1
Sood2 / 2004 / 3 / 3 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 2 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 16 / 0 / 11 / 0 / 11
Tada5 / 2005 / 3 / 3 / 0 / 2 / 0 / 2
Boughey6 / 2006 / 21 / 17 / 4 / NR / NR / 10
Jackson7 / 2006 / 1 / 1 / 0 / 1 / 0 / 1
Newman8 / 2006 / 10 / 10 / 0 / 8 / 0 / 8
Roumen9 / 2006 / 12 / 10 / 2 / 8 / 2 / 10
Taback10 / 2006 / 15 / 15 / 0 / 11 / 0 / 11
Barone11 / 2007 / 19 / 19 / 0 / NR / NR / NR
Intra12 / 2007 / 65 / 65 / 0 / 63 / 0 / 63
Port13 / 2007 / 117 / 117 / 0 / 63 / 0 / 63
Axelsson14 / 2008 / 47 / 33 / 14 / NR / NR / 24
Cox15 / 2008 / 56 / NR / NR / NR / NR / NR
Karam16 / 2008 / 20 / 0 / 20 / 0 / 15 / 15
Koizumi17 / 2008 / 31 / 31 / 0 / 29 / 0 / 29
Schrenk18 / 2008 / 30 / 29 / 1 / NR / NR / 19
Tasevski19 / 2009 / 18 / 16 / 2 / NR / NR / 12
Van derPloeg20 / 2010 / 48 / 48 / 0 / 32 / 0 / 32
Vicente21 / 2010 / 1 / 0 / 1 / 0 / 1 / 1
Yamashita22 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 45 / 0 / 11 / 0 / 11
Maaskant-Braat25 / 2011 / 109 / 92 / 17 / 63 / 12 / 75
Total
Total-NR
Total-NR
(LM performed)
Percentage (%)
95% CI / 692 / 574
636
90.3 / 62
636
9.8 / 309
425
72.7
68.2-76.8 / 31
41
75.6
59.4-87.1 / 405
572
70.8
66.9-74.5

N: Number; LM: Lymphatic mapping; BCT: Breast conserving treatment; Lump: Lumpectomy; Mast: Mastectomy; NR: Not recorded; CI: Confidence interval

Table 7 Sentinel node biopsy success rates of 692 patients with locally recurrent breast cancer stratified according to previous axillary procedure

Author / Year / N / Axillary procedure
ALND / SNB successful
SNB / ALND / None / SNB / ALND / None / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Sood2 / 2004 / 3 / 0 / 3 / 0 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 0 / 2 / 0 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 2 / 14 / 0 / 2 / 9 / 0 / 11
Tada5 / 2005 / 3 / 0 / 2 / 1 / 0 / 1 / 1 / 2
Boughey6 / 2006 / 21 / 5 / 12 / 4 / 5 / 6 / 2 / 13
Jackson7 / 2006 / 1 / 1 / 0 / 0 / 1 / 0 / 0 / 1
Newman8 / 2006 / 10 / 1 / 7 / 2 / 1 / 7 / 1 / 9
Roumen9 / 2006 / 12 / 2 / 10 / 0 / 2 / 8 / 0 / 10
Taback10 / 2006 / 15 / 6 / 9 / 0 / 5 / 6 / 0 / 11
Barone11 / 2007 / 19 / 7 / 12 / 0 / 7 / 9 / 0 / 16
Intra12 / 2007 / 65 / 65 / 0 / 0 / 63 / 0 / 0 / 63
Port13 / 2007 / 117 / 54 / 63 / 0 / 40 / 24 / 0 / 64
Axelsson14 / 2008 / 47 / 1 / 43 / 3 / NR / NR / NR / 20
Cox15 / 2008 / 56 / 56 / 0 / 0 / 45 / 0 / 0 / 45
Karam16 / 2008 / 20 / 4 / 11 / 5 / 4 / 5 / 4 / 13
Koizumi17 / 2008 / 31 / 3 / 16 / 12 / 3 / 13 / 12 / 28
Schrenk18 / 2008 / 30 / 15 / 13 / 2 / 12 / 5 / 2 / 19
Tasevski19 / 2009 / 18 / 3 / 15 / 0 / 2 / 10 / 0 / 12
Van derPloeg20 / 2010 / 48 / 36 / 12 / 0 / 26 / 6 / 0 / 32
Vicente21 / 2010 / 1 / 0 / 0 / 1 / 0 / 0 / 1 / 1
Yamashita22 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 0 / 45 / 0 / 0 / 13 / 0 / 13
Maaskant-Braat25 / 2011 / 109 / 40 / 69 / 0 / 25 / 36 / 0 / 61
Total
Total-NR
Percentage (%)
95% CI / 692 / 301
692
43.5 / 361
692
52.2 / 30
692
4.3 / 243
300
81.0
76.0-85.2 / 166
318
52.2
46.6-57.8 / 23
27
85.2
65.4-95.1 / 452
692
65.3
61.6-68.8

N: Number; SNB: Sentinel node biopsy; ALND: Axillary lymph node dissection; NR: Not recorded; CI: Confidence interval

Table 8 Sentinel node biopsy success rates of 636 patients with locally recurrent breast cancer stratified according to previous breast treatment

Author / Year / N / Breast treatment / SNB successful
BCT/Lump / Mast / BCT/Lump / Mast / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 1 / 1
Sood2 / 2004 / 3 / 3 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 2 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 16 / 0 / 11 / 0 / 11
Tada5 / 2005 / 3 / 3 / 0 / 2 / 0 / 2
Boughey6 / 2006 / 21 / 17 / 4 / 11 / 2 / 13
Jackson7 / 2006 / 1 / 1 / 0 / 1 / 0 / 1
Newman8 / 2006 / 10 / 10 / 0 / 9 / 0 / 9
Roumen9 / 2006 / 12 / 10 / 2 / 8 / 2 / 10
Taback10 / 2006 / 15 / 15 / 0 / 11 / 0 / 11
Barone11 / 2007 / 19 / 19 / 0 / 16 / 0 / 16
Intra12 / 2007 / 65 / 65 / 0 / 63 / 0 / 63
Port13 / 2007 / 117 / 117 / 0 / 64 / 0 / 64
Axelsson14 / 2008 / 47 / 33 / 14 / NR / NR / 20
Cox15 / 2008 / 56 / NR / NR / NR / NR / 45
Karam16 / 2008 / 20 / 0 / 20 / 0 / 13 / 13
Koizumi17 / 2008 / 31 / 31 / 0 / 28 / 0 / 28
Schrenk18 / 2008 / 30 / 29 / 1 / NR / NR / 19
Tasevski19 / 2009 / 18 / 16 / 2 / NR / NR / 12
Van derPloeg20 / 2010 / 48 / 48 / 0 / 32 / 0 / 32
Vicente21 / 2010 / 1 / 0 / 1 / 0 / 1 / 1
Yamashita22 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 45 / 0 / 13 / 0 / 13
Maaskant-Braat25 / 2011 / 109 / 92 / 17 / 49 / 12 / 61
Total
Total-NR
Percentage (%)
95% CI / 692 / 574
636
90.3 / 62
636
9.8 / 325
496
65.5
61.1-69.7 / 31
45
68.9
53.2-81.4 / 452
692
65.3
61.6-68.8

N: Number; SNB: Sentinel node biopsy; BCT: Breast conserving treatment; Lump: Lumpectomy; Mast: Mastectomy; NR: Not recorded; CI: Confidence interval

Table 9 Aberrant drainage rates of 692 patients with locally recurrent breast cancer stratified according to previous axillary procedure

Author / Year / N / Axillary procedure
ALND / Aberrant drainage
SNB / ALND / None / SNB / ALND / None / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Sood2 / 2004 / 3 / 0 / 3 / 0 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 0 / 2 / 0 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 2 / 14 / 0 / 2 / 6 / 0 / 8
Tada5 / 2005 / 3 / 0 / 2 / 1 / 0 / 1 / 1 / 2
Boughey6 / 2006 / 21 / 5 / 12 / 4 / 2 / 4 / 0 / 6
Jackson7 / 2006 / 1 / 1 / 0 / 0 / 0 / 0 / 0 / 0
Newman8 / 2006 / 10 / 1 / 7 / 2 / 0 / 7 / 0 / 7
Roumen9 / 2006 / 12 / 2 / 10 / 0 / 0 / 7 / 0 / 7
Taback10 / 2006 / 15 / 6 / 9 / 0 / 3 / 4 / 0 / 7
Barone11 / 2007 / 19 / 7 / 12 / 0 / NR / NR / NR / NR
Intra12 / 2007 / 65 / 65 / 0 / 0 / 5 / 0 / 0 / 5
Port13 / 2007 / 117 / 54 / 63 / 0 / 3 / 16 / 0 / 19
Axelsson14 / 2008 / 47 / 1 / 43 / 3 / NR / NR / NR / 7
Cox15 / 2008 / 56 / 56 / 0 / 0 / 1 / 0 / 0 / 1
Karam16 / 2008 / 20 / 4 / 11 / 5 / NR / NR / NR / 2
Koizumi17 / 2008 / 31 / 3 / 16 / 12 / 1 / 7 / 4 / 12
Schrenk18 / 2008 / 30 / 15 / 13 / 2 / 2 / 3 / 0 / 5
Tasevski19 / 2009 / 18 / 3 / 15 / 0 / 0 / 8 / 0 / 8
Van derPloeg20 / 2010 / 48 / 36 / 12 / 0 / 17 / 6 / 0 / 23
Vicente21 / 2010 / 1 / 0 / 0 / 1 / 0 / 0 / 0 / 0
Yamashita22 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 0 / 1 / 0 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 0 / 45 / 0 / 0 / 5 / 0 / 5
Maaskant-Braat25 / 2011 / 109 / 40 / 69 / 0 / 7 / 36 / 0 / 43
Total
Total-NR
Total-NR
(LM successful)
Percentage (%)
95% CI / 692 / 301
692
43.5 / 361
692
52.2 / 30
692
4.3 / 43
37
144
25.7
18.9-33.8 / 118
98
132
74.2
65.8-81.3 / 5
5
17
29.4
11.4-56.0 / 175
405
43.2
38.4-48.2

N: Number; SNB: Sentinel node biopsy; ALND: Axillary lymph node dissection; NR: Not recorded; LM: Lymphatic mapping; CI: Confidence interval

Table 10 Aberrant drainage rates of 636 patients with locally recurrent breast cancer stratified according to previous breast treatment

Author / Year / N / Breast treatment / Aberrant drainage
BCT/Lump / Mast / BCT/Lump / Mast / Total
Lim1 / 2004 / 1 / 0 / 1 / 0 / 1 / 1
Sood2 / 2004 / 3 / 3 / 0 / 3 / 0 / 3
Agarwal3 / 2005 / 2 / 2 / 0 / 2 / 0 / 2
Dinan4 / 2005 / 16 / 16 / 0 / 8 / 0 / 8
Tada5 / 2005 / 3 / 3 / 0 / 2 / 0 / 2
Boughey6 / 2006 / 21 / 17 / 4 / 4 / 2 / 6
Jackson7 / 2006 / 1 / 1 / 0 / 0 / 0 / 0
Newman8 / 2006 / 10 / 10 / 0 / 7 / 0 / 7
Roumen9 / 2006 / 12 / 10 / 2 / 7 / 0 / 7
Taback10 / 2006 / 15 / 15 / 0 / 7 / 0 / 7
Barone11 / 2007 / 19 / 19 / 0 / NR / NR / NR
Intra12 / 2007 / 65 / 65 / 0 / 5 / 0 / 5
Port13 / 2007 / 117 / 117 / 0 / 19 / 0 / 19
Axelsson14 / 2008 / 47 / 33 / 14 / NR / NR / 7
Cox15 / 2008 / 56 / NR / NR / NR / NR / 1
Karam16 / 2008 / 20 / 0 / 20 / 0 / 2 / 2
Koizumi17 / 2008 / 31 / 31 / 0 / 0 / 12 / 12
Schrenk18 / 2008 / 30 / 29 / 1 / NR / NR / 5
Tasevski19 / 2009 / 18 / 16 / 2 / NR / NR / 8
Van derPloeg20 / 2010 / 48 / 48 / 0 / 23 / 0 / 23
Vicente21 / 2010 / 1 / 0 / 1 / 0 / 0 / 0
Yamashita22 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Hattori23 / 2011 / 1 / 1 / 0 / 1 / 0 / 1
Kaur24 / 2011 / 45 / 45 / 0 / 5 / 0 / 5
Maaskant-Braat25 / 2011 / 109 / 92 / 17 / 34 / 9 / 43
Total
Total-NR
Total-NR
(LM successful)
Percentage (%)
95% CI / 692 / 574
636
90.3 / 62
636
9.8 / 128
124
309
40.1
34.7-45.8 / 26
24
31
77.4
58.5-89.7 / 175
405
43.2
38.4-48.2

N: Number; BCT: Breast conserving treatment; Lump: Lumpectomy; Mast: Mastectomy; NR: Not recorded; LM: Lymphatic mapping; CI: Confidence interval

References

  1. Lim I, Shim J, Goyenechea M, Kim CK, Krynyckyi BR. Drainage across midline to sentinel nodes in the contralateral axilla in breast cancer. Clin Nucl Med 2004; 29: 346-347.
  2. Sood A, Youssef IM, Heiba SI, El-Zeftawy H, Axelrod D, Seigel B, Mills C, et al. Alternative lymphatic pathway after previous axillary node dissection in recurrent/primary breast cancer. ClinNucl Med 2004; 29: 698-702.
  3. Agarwal A, Heron DE, Sumkin J, Falk J. Contralateral uptake and metastases in sentinel lymph node mapping for recurrent breast cancer. J Surg Oncol 2005; 92: 4-8.
  4. Dinan D, Nagle CE, Pettinga J. Lymphatic mapping and sentinel node biopsy in women with an ipsilateral second breast carcinoma and a history of breast and axillary surgery. Am J Surg 2005; 190: 614-617.
  5. Tada K, Nishimura S, Miyagi Y, et al. The effect of an old surgical scar on sentinel node mapping in patients with breast cancer: A report of five cases. Eur J Surg Oncol 2005; 31: 840-844.
  6. BougheyJC, Ross MI, Babiera GV, et. al. Sentinel lymph node surgery in locally recurrent breast cancer. Clin Breast Cancer 2006; 7: 248-253.
  7. Jackson BM, Kim S, Davidson R, Schuchter L, Acs G, Czerniecki BJ. Repeat operative sentinel lymph node biopsy. Clin Breast Cancer 2006; 6: 530-532.
  8. Newman EA, CimminoVM, Sabel MS, Diehl KM, Frey KA, Chang AE, Newman LA. Lymphatic mapping and sentinel lymph node biopsy for patients with local recurrence after breast-conservation therapy. Ann Surg Oncol 2006; 13: 52-57.
  9. RoumenRMH, Kuijt GP, LiemIH. Lymphatic mapping and sentinel node harvesting in patients with recurrent breast cancer. Eur J Surg Oncol 2006; 32: 1076-1081.
  10. Taback B, Nguyen P, Hansen N, Edwards GK, Conway K, Giuliano AE. Sentinel lymph node biopsy for local recurrence of breast cancer after breast-conserving therapy. Ann Surg Oncol 2006; 13: 1099-1104.
  11. BaroneJL, Feldman SM, Estabrook A, Tartter PI, Rosenbaum Smith SM, Boolbol SK. Reoperative sentinel lymph node biopsy in patients with locally recurrent breast cancer. Am J Surg 2007; 194: 491-493.
  12. Intra M, Trifirò G, Galimberti V, Gentilini O, Rotmensz N, Veronesi P. Second axillary sentinel node biopsy for ipsilateral breast tumour recurrence. Br J Surg 2007; 94:1216-1219.
  13. Port ER, Garcia-Etienne CA, Park J, Fey J, Borgen PI, Cody HS 3rd. Reoperative sentinel lymph node biopsy: a new frontier in the management of ipsilateral breast tumor recurrence. Ann Surg Oncol 2007; 14: 2209-2214.
  14. Axelsson CK, Jonsson PE. Sentinel lymph node biopsy in operations for recurrent breast cancer. Eur J Surg Oncol 2008; 34: 626-30.
  15. Cox CE, Furman BT, Kiluk JV, et al. Use of reoperative sentinel lymph node biopsy in breast cancer patients. J Am Coll Surg 2008; 207: 57-61.
  16. Karam A, Stempel M, Cody HS, Port ER. Reoperative sentinel lymph node biopsy after previous mastectomy. J Am Coll Surg 2008; 207: 543-548.
  17. Koizumi M, Koyama M, Tada K, et. al. The feasibility of sentinel node biopsy in the previously treated breast. Eur J Surg Oncol 2008; 34: 365-368.
  18. Schrenk P, Tausch C, Wayand W. Lymphatic mapping in patients with primary or recurrent breast cancer following previous axillary surgery. Eur J Surg Oncol 2008; 34: 851-856.
  19. Tasevski R, Gogos AJ, Mann GB. Reoperative sentinel lymph node biopsy in ipsilateral breast cancer relapse. The Breast 2009; 18: 322-326.
  20. Van derPloeg IMC, Oldenburg HSA, Rutgers EJT, et. al. Lymphatic drainage patterns from the treated breast. Ann Surg Oncol 2010; 17: 1069-1075.
  21. Vicente DA, Henry LR, Hahm G, Soballe PW, Smart D. Axillary sentinel lymph node biopsy after mastectomy: a case report. World J Surg Oncol 2010; 8: 59.
  22. Yamashita T, Fujita T, Hayahi H, et. al. Detection of parasternal metastatic lymph nodes by sentinel lymph node methods in a patient with recurrence in the conserved breast. Breast Cancer 2011; DOI 10.1007/s12282-010-0248-z.
  23. Hattori M, Nishimura S, Tada K, et. al. Reoperative sentinel lymph node biopsy for ipsilateral breast tumor recurrence after previous axillary lymph node dissection: Report of a case. Surg Today 2011; 41: 247-250.
  24. Kaur P, Kiluk JV, Meade T, et. al. Sentinel lymph node biopsy in patients with previous ipsilateral complete axillary lymph node dissection. Ann Surg Oncol 2011; 18: 727-732.
  25. Maaskant-Braat A, Roumen R, Pijpers H, Nieuwenhuijzen GAP. Sentinel Node And Recurrent Breast cancer (SNARB): Results of an interim-analysis. Ann Surg Oncol 2011; 18: S1-S144. Abstract 37.DOI 10.1245/s10434-011-1552-3.