Table S3. Down-regulated expression of 1398 probesets after treatment with 5 µM BI-D1870 vs DMSO for 24 or 48 hours.

WM 278 / WM 3248
Gene Symbol/ Locus / Public ID / 24 h / 48 h / 24 h / 48 h
DDR1 / U48705 / -1.4496567 / -1.3474988 / -1.4151721 / -1.4688578
HDGF / NM_004494 / -1.6600568 / -1.3496058 / -1.7430475 / -2.1152606
SSRP1 / NM_003146 / -1.4954778 / -1.3766361 / -1.5258166 / -1.614424
ABLIM1 / NM_006720 / -2.4173126 / -3.1762617 / -2.8348203 / -1.5873702
MMP2 / NM_004530 / -2.710742 / -4.5962844 / -1.5171047 / -1.6104616
HLA-DPB1 / NM_002121 / -1.9348937 / -3.8365939 / -1.8686175 / -2.5020673
TIMP3 / U67195 / -3.0880225 / -5.264646 / -1.4447896 / -1.6796824
FDPS / NM_002004 / -1.4181707 / -2.4194908 / -1.4307511 / -1.6008666
ARHGDIB / NM_001175 / -4.925043 / -4.4026966 / -2.3851395 / -2.651757
ANP32B / NM_006401 / -1.3835129 / -1.4260626 / -1.4198765 / -1.4638401
NREP (C5orf13) / NM_004772 / -2.2769141 / -2.028608 / -2.0460794 / -1.9224002
IFITM2 / NM_006435 / -1.965437 / -2.8548498 / -1.7767178 / -2.2157047
EMP1 / NM_001423 / -1.3543129 / -2.8111928 / -1.9251108 / -2.0628967
EMP1 / NM_001423 / -1.4574627 / -2.7211812 / -1.9132224 / -1.9616067
ETS2 / AL575509 / -4.075384 / -2.8851225 / -2.2247374 / -2.2876914
ETS2 / NM_005239 / -3.6290884 / -2.1380517 / -1.8947738 / -1.6534213
STAT6 / BC004973 / -1.970155 / -2.5345826 / -1.4796731 / -1.8551266
UBAP2L / NM_014847 / -1.5695101 / -1.4424369 / -1.4779209 / -1.5445278
WDR77 / NM_024102 / -1.4176247 / -1.4087304 / -1.3939464 / -1.3449008
PODXL / NM_005397 / -2.9808242 / -2.802361 / -1.5257262 / -1.6293458
IRAK1 / NM_001569 / -1.5101843 / -1.7278267 / -1.9204589 / -2.3062186
IFITM1 / NM_003641 / -3.146857 / -3.4274857 / -2.399501 / -2.7481565
CALD1 / AI685060 / -1.904186 / -4.209134 / -1.6196092 / -1.6443198
CALD1 / AL577531 / -2.4989622 / -4.1106873 / -1.464492 / -1.6246098
CALD1 / NM_004342 / -2.4946916 / -3.6179168 / -1.4218658 / -1.5716455
MARCKS / AW163148 / -1.3647386 / -1.5278821 / -2.0565133 / -1.6153181
MARCKS / NM_002356 / -1.3836094 / -1.5687871 / -1.6317062 / -1.543071
MARCKS / M68956 / -1.4994907 / -1.5697545 / -1.8428522 / -1.6743801
LAPTM5 / AI589086 / -3.0822775 / -3.1129913 / -3.0445144 / -2.2380555
LAPTM5 / NM_006762 / -4.044283 / -4.475812 / -2.583601 / -2.5753355
LUM / NM_002345 / -1.7420269 / -2.014361 / -2.638017 / -2.5123587
TP53 / NM_000546 / -1.6866807 / -2.7609358 / -1.7660716 / -2.1434944
VARS / NM_006295 / -1.3706036 / -2.0680873 / -1.4528109 / -1.7172078
SCARB1 / NM_005505 / -2.0742595 / -2.5327663 / -1.4544283 / -1.3539203
HSPB1 / NM_001540 / -1.7571405 / -1.6827909 / -1.5343815 / -1.5728399
SRGN / J03223 / -1.9841034 / -2.7711892 / -1.7986705 / -1.9823886
SRGN / NM_002727 / -2.110283 / -2.622016 / -1.6289839 / -1.8007251
PON2 / NM_000305 / -1.747778 / -2.0655794 / -1.5984805 / -1.5576117
CD55 / NM_000574 / -2.0843203 / -1.7816045 / -1.6771628 / -1.5062917
PLK2 / NM_006622 / -2.4854255 / -3.7352333 / -2.4028566 / -1.7226304
PPP1R12B / AF324888 / -1.466024 / -2.0751045 / -2.0451152 / -3.2137835
PAPPA / AA148534 / -3.6788287 / -7.229223 / -1.9378834 / -1.4445882
BRD4 / AI991631 / -1.7211893 / -1.4147652 / -2.1562202 / -1.5721645
CELF2 / N36839 / -1.9226135 / -2.0232077 / -2.0382462 / -1.3894356
CELF2 / U69546 / -2.1635563 / -1.7838984 / -1.8977575 / -1.3314776
CELF2 / NM_006561 / -1.9456421 / -1.8113297 / -1.9222726 / -1.4145864
DKK3 / NM_013253 / -1.5205244 / -2.1049762 / -1.7920865 / -1.8514143
LAMA4 / NM_002290 / -1.3815261 / -1.8768195 / -1.6858332 / -1.4856684
VASP / NM_003370 / -1.6188643 / -1.6032703 / -1.3660601 / -1.4069847
NNMT / NM_006169 / -4.314337 / -11.906918 / -4.7251444 / -3.8528225
NNMT / NM_006169 / -3.9612029 / -9.195412 / -4.2143245 / -3.9279182
RAB13 / NM_002870 / -2.003569 / -1.8602289 / -1.4114271 / -1.4261215
GBP1 / BC002666 / -4.551041 / -6.4358673 / -5.88685 / -3.0135047
GBP1 / NM_002053 / -5.3626666 / -6.9838786 / -5.8356853 / -3.173901
MGP / NM_000900 / -10.26035 / -24.449215 / -4.4995923 / -7.679996
FABP5 / NM_001444 / -1.5334632 / -1.5530016 / -1.637132 / -2.2461953
MATN2 / NM_002380 / -1.735285 / -2.1466103 / -2.012808 / -1.6409951
SPOCK1 / AF231124 / -1.33947 / -1.5949059 / -1.5699122 / -1.6508398
SERPINA3 / NM_001085 / -4.391842 / -2.9500687 / -2.1812282 / -1.3598955
IFI27 / NM_005532 / -1.4299064 / -1.5940155 / -1.6381903 / -4.4283495
PLSCR1 / NM_021105 / -1.59877 / -1.6040078 / -1.4238688 / -1.6415105
PLSCR1 / AI825926 / -1.54787 / -1.5720686 / -1.5023447 / -1.7895002
ERBB3 / NM_001982 / -3.0254283 / -1.8073281 / -1.5565943 / -1.6969328
PRSS23 / NM_007173 / -1.7150625 / -1.884736 / -1.676445 / -1.5015798
SNRPB2 / NM_003092 / -2.1306074 / -1.743138 / -1.6591029 / -1.6973782
TNFAIP2 / NM_006291 / -1.6393892 / -1.9301549 / -1.7788452 / -2.6181512
SVIL / NM_003174 / -2.038838 / -2.0471063 / -1.5479493 / -1.3424844
ICAM1 / AI608725 / -2.161628 / -1.9402398 / -1.6405771 / -1.8552707
ICAM1 / NM_000201 / -2.1432064 / -1.8598028 / -1.6313142 / -1.6962779
PKIG / NM_007066 / -1.4809922 / -1.7303362 / -1.5146062 / -1.637611
ABHD14A / NM_000666 / -1.7502754 / -2.3633518 / -1.6208662 / -2.2728574
GBP2 / NM_004120 / -1.6967345 / -1.4695803 / -1.6028143 / -1.7602053
SYNPO / NM_007286 / -2.377489 / -2.4684727 / -1.9196075 / -2.1273458
CLPP / NM_006012 / -2.3374586 / -1.9726264 / -1.8465983 / -1.9415067
IL8 / NM_000584 / -8.140757 / -5.8178144 / -2.5906034 / -4.6416454
SP100 / NM_003113 / -1.4709365 / -1.5457759 / -1.4690714 / -1.622005
OAS1 / NM_016816 / -3.2903264 / -3.0379505 / -1.9685493 / -2.9504633
PBX2 / BE397715 / -1.6761861 / -1.3460786 / -1.6678262 / -1.6520725
SIRPA / AB023430 / -1.7340235 / -2.2177858 / -1.8307519 / -1.7780582
CTSS / BC002642 / -2.0241506 / -1.8428478 / -3.824034 / -3.7042167
CTSS / NM_004079 / -2.906338 / -2.7945037 / -6.0903835 / -6.794959
CD97 / NM_001784 / -1.7291512 / -1.4954343 / -1.8646001 / -1.9802669
GYPC / NM_002101 / -1.9016017 / -2.2683046 / -1.4401641 / -1.963534
RFX5 / AW027312 / -1.5425024 / -1.3524122 / -1.9186164 / -1.6759038
FAM13A / NM_014883 / -2.4338799 / -2.3496082 / -1.5484533 / -1.7038757
ACOT1 / NM_006821 / -3.4082453 / -3.2063022 / -1.9222014 / -1.8228552
STAT5A / NM_003152 / -1.7393345 / -1.8624011 / -1.4692947 / -1.5589861
C5orf15 / NM_020199 / -1.5380225 / -1.4246935 / -1.5969822 / -1.4608854
SEMA3B / NM_004636 / -3.4847052 / -3.9967108 / -1.4554726 / -1.3559988
GPRC5A / NM_003979 / -1.8112516 / -2.8011951 / -1.5801833 / -1.7364768
CCDC86 / NM_024098 / -1.4442468 / -1.6793754 / -1.3399395 / -1.5412508
MTMR2 / AK027038 / -2.0909643 / -1.8887838 / -1.73783 / -1.7128204
MTMR2 / NM_016156 / -2.6168153 / -2.2698271 / -1.9859444 / -1.7183572
ST3GAL5 / NM_003896 / -2.3507311 / -1.8926615 / -1.630621 / -1.3894781
NSMAF / NM_003580 / -2.0086133 / -1.8032528 / -1.3745139 / -1.4835001
HLA-DQA1 / NM_002122 / -1.6330855 / -1.793937 / -1.7937175 / -2.8439019
SLC25A12 / AI887457 / -1.4398029 / -1.6289753 / -1.6398877 / -1.5520234
SLC25A12 / NM_003705 / -1.7105794 / -1.5866076 / -1.5043962 / -1.517319
UGDH / NM_003359 / -1.5487093 / -1.5885462 / -1.477521 / -1.3347881
ETV5 / BF060791 / -2.0869355 / -1.7823949 / -3.496359 / -2.4686053
ETV5 / NM_004454 / -2.8010879 / -2.1060805 / -4.441865 / -3.1365461
IQGAP2 / NM_006633 / -2.9282918 / -3.0460927 / -4.7415357 / -3.4005785
COL15A1 / NM_001855 / -2.0605295 / -2.4187424 / -2.5998592 / -2.9268486
NDUFC1 / NM_002494 / -1.5314772 / -1.6431129 / -1.5040762 / -1.3457131
LPHN1 / NM_014921 / -1.5164388 / -1.9387736 / -1.5205116 / -1.5029656
KLF9 / AI690205 / -4.706197 / -3.3687425 / -4.2133236 / -2.5381799
KLF9 / NM_001206 / -4.8625674 / -2.8932166 / -3.9418185 / -2.1594644
LPL / BF672975 / -2.0333285 / -1.6523335 / -1.8198586 / -1.724879
LPL / NM_000237 / -2.1603231 / -1.682777 / -2.0874655 / -1.8783331
ZHX2 / NM_014943 / -6.1546097 / -3.5604901 / -2.2985113 / -1.8445591
FCGR2A / NM_021642 / -6.066143 / -5.0924053 / -3.0365367 / -3.5707266
BYSL / NM_004053 / -1.4354817 / -1.6252388 / -1.5754814 / -1.6324401
RREB1 / AW118862 / -1.6677577 / -1.7776603 / -1.4522704 / -1.3463778
PDE4B / NM_002600 / -5.6765866 / -3.8010368 / -6.9952126 / -4.24021
ITPKB / NM_002221 / -4.4320908 / -2.8568013 / -2.5627534 / -2.574039
EMP3 / NM_001425 / -1.7416965 / -1.7890655 / -1.3926008 / -1.7834338
TCF4 / NM_003199 / -1.4392961 / -1.6371174 / -2.229214 / -2.3573008
MAP3K5 / D84476 / -1.6032461 / -1.8903764 / -2.004297 / -2.121246
MAP3K5 / NM_005923 / -1.9160796 / -1.9692641 / -2.1909018 / -2.3619015
CFI / NM_000204 / -3.6600342 / -11.267081 / -1.8237971 / -5.22233
HLA-DMB / NM_002118 / -2.6853762 / -2.383031 / -2.1764874 / -1.5885051
CA12 / NM_001218 / -7.0099173 / -8.380835 / -2.440509 / -1.9492359
NMI / NM_004688 / -2.9731424 / -3.1351008 / -2.0540934 / -1.8705257
CYP27A1 / NM_000784 / -1.7555226 / -1.6482911 / -1.6235819 / -1.4613297
SH3YL1 / NM_015677 / -2.3237019 / -2.0955057 / -1.9260164 / -1.5258758
IQCJ-SCHIP1 / NM_014575 / -1.918378 / -2.1409936 / -2.4106793 / -1.8872075
LPAR1 / AW269335 / -6.13011 / -5.5307055 / -2.3113163 / -1.4546918
RARRES3 / NM_004585 / -2.8916364 / -4.3846 / -2.8422422 / -4.3615694
MYRF (C11orf9) / NM_013279 / -1.3954127 / -1.337047 / -1.9866849 / -1.33105
SLC5A6 / NM_021095 / -2.156318 / -3.4351857 / -1.775741 / -1.9814346
GNG11 / NM_004126 / -2.1424162 / -2.6296656 / -2.090329 / -2.0583043
AKR1C1 / NM_001353 / -2.1127396 / -1.7810669 / -2.2107291 / -1.5429043
EMILIN1 / NM_007046 / -3.2884336 / -4.2881303 / -2.042802 / -2.6954284
MGST2 / NM_002413 / -2.668589 / -2.8507247 / -1.5835111 / -1.6351253
RUNX3 / NM_004350 / -1.8014823 / -1.6882716 / -1.3891557 / -1.574637
RUNX3 / AA541630 / -2.3200223 / -1.6566045 / -1.3507295 / -1.5495791
PDGFB / NM_002608 / -2.6801703 / -5.5504804 / -1.4380395 / -1.8286521
GLIPR1 / U16307 / -1.9436952 / -2.677257 / -1.7660611 / -2.1304612
GLIPR1 / NM_006851 / -2.9923348 / -5.795366 / -3.267299 / -2.5876698
HDAC4 / NM_006037 / -1.4156338 / -1.4240584 / -1.5899895 / -1.4708962
DNPH1 (C6orf108) / NM_006443 / -1.6865678 / -2.7791886 / -1.3349808 / -1.6731752
ELOVL6 / NM_024090 / -1.5333939 / -1.771793 / -1.5462608 / -1.365503
MMP7 / NM_002423 / -1.7037016 / -1.7238606 / -3.1154509 / -5.8432307
GPSM3 / NM_022107 / -1.3787123 / -1.6196513 / -1.9938549 / -1.7973614
S100A2 / NM_005978 / -3.1443472 / -2.0607378 / -1.9969589 / -1.6683179
EDNRB / M74921 / -1.7821728 / -1.4331237 / -2.0774515 / -1.6721646
EDNRB / NM_000115 / -2.5737774 / -1.5929415 / -2.3216414 / -1.6897169
PSMB9 / NM_002800 / -1.7199962 / -1.6502558 / -1.8125727 / -1.7969961
COL11A1 / NM_001854 / -1.6457636 / -1.8350055 / -3.5771453 / -5.487499
COL16A1 / NM_001856 / -4.059667 / -6.6256814 / -3.0775418 / -3.2518423
TRAF5 / NM_004619 / -1.5863144 / -1.5990648 / -1.9320205 / -2.047162
KYNU / NM_003937 / -2.9988923 / -3.2453654 / -4.9524 / -4.298935
EFS / NM_005864 / -2.107757 / -1.861571 / -1.5985259 / -1.8651073
RHBDD3 / NM_012265 / -1.4977611 / -1.6234461 / -1.3462924 / -1.3711618
IFI6 / NM_022873 / -1.3343086 / -1.5859618 / -1.5636638 / -1.7847978
APOC1 / NM_001645 / -1.6325003 / -1.7684784 / -2.396191 / -2.6786945
GALC / NM_000153 / -6.433649 / -10.24854 / -2.060893 / -3.0806134
FGF2 / M27968 / -1.6971684 / -1.5072198 / -2.4370592 / -2.0082443
FGF2 / NM_002006 / -1.7348694 / -2.033877 / -2.9099808 / -2.3962057
IFI44L / NM_006820 / -2.8741841 / -4.0356836 / -2.423558 / -5.744996
GAS1 / NM_002048 / -2.6778274 / -2.5154986 / -2.245651 / -1.818526
PTPRZ1 / NM_002851 / -4.2739573 / -3.6776574 / -3.9155939 / -2.4946282
CXCL1 / NM_001511 / -4.308309 / -6.422075 / -2.296534 / -5.8183856
CA12 / BC001012 / -3.911264 / -4.350244 / -1.3426657 / -1.7171425
HIVEP1 / NM_002114 / -1.8610582 / -2.1765597 / -1.890607 / -1.3661184
PLLP / NM_015993 / -3.4825044 / -2.7030365 / -6.3678513 / -7.837339
FAM216A (C12orf24) / NM_013300 / -1.5424126 / -1.623077 / -1.5165132 / -1.8508352
DLG4 / NM_001365 / -1.4725374 / -1.3511953 / -1.7717077 / -1.6340995
NR4A2 / NM_006186 / -1.890212 / -2.1037676 / -1.3743787 / -1.4012908
ACP5 / NM_001611 / -3.3853633 / -4.2755933 / -2.0322058 / -2.1461499
HOMER3 / NM_004838 / -1.4165901 / -1.6523286 / -1.756644 / -1.9216512
HLA-DRB1/4 / NM_002125 / -1.6115494 / -2.603312 / -1.6157174 / -1.9641902
RAPGEF5 / AI263837 / -1.4447861 / -1.463687 / -1.9906738 / -1.9942615
RAPGEF5 / NM_012294 / -4.311616 / -3.47392 / -4.9517536 / -4.9855704
ISG20 / NM_002201 / -3.4139132 / -3.2773027 / -2.7009728 / -2.3208852
DIEXF (C1orf107) / NM_014388 / -1.4204944 / -1.9807667 / -1.7012081 / -1.9113858
NFE2L3 / NM_004289 / -1.4198544 / -1.4525901 / -1.8560349 / -1.3714322
ABCA8 / NM_007168 / -4.9770436 / -4.860641 / -3.481186 / -3.8734024
COL9A3 / NM_001853 / -1.8702719 / -2.4909303 / -1.4413017 / -1.6930801
IFIT3 / NM_001549 / -1.6232951 / -2.0337856 / -1.6764115 / -1.4897841
TAP2 / M74447 / -1.4116791 / -1.4927558 / -1.5475273 / -1.5798328
EVI2A / NM_014210 / -2.716325 / -1.6210971 / -1.938568 / -1.5711904
HOXB7 / AW102783 / -3.2378259 / -3.4235127 / -2.2517598 / -2.166133
HOXB7 / NM_004502 / -3.414267 / -3.1339355 / -2.1691637 / -2.2459369
FAS / AA164751 / -1.5116615 / -1.8183644 / -2.6419969 / -1.8081921
FAS / NM_000043 / -1.5503348 / -1.5588742 / -2.0989754 / -2.0404463
BTN3A2/3 / NM_006994 / -2.9048615 / -2.5565486 / -2.3114238 / -2.3763075
BTN3A3 / NM_006994 / -2.922703 / -3.0860133 / -2.7210548 / -2.5091023
NAV3 / NM_014903 / -2.7963552 / -8.989082 / -5.939098 / -1.9070641
BCL3 / NM_005178 / -2.4954321 / -1.5321838 / -1.8204938 / -1.4959558
RAMP1 / NM_005855 / -2.3574076 / -1.7354021 / -2.7475338 / -1.9317575
FST / NM_013409 / -1.9955492 / -1.7819281 / -2.857187 / -1.78924