Table S1.Raw Ct values (average + SEM) for each new PGC-1 target gene following transduction of C2C12 myotubes with adenoviruses encoding GFP or PGC-1

Gene / GFP / PGC-1
Akr1b10 / 26.34 + 0.14 / 25.38 + 0.05
Rmnd1 / 27.63 + 0.12 / 26.75 + 0.08
1110008P14Rik / 24.85 + 0.05 / 23.39 + 0.11
1700021F05Rik / 22.49 + 0.18 / 20.97 + 0.06
Mtfp1 / 29.69 + 0.05 / 28.04 + 0.11
Mrm1 / 29.76 + 0.12 / 28.53 + 0.16
Oxnad1 / 26.31 + 0.08 / 23.94 + 0.16
Cluh / 21.76 + 0.41 / 19.93 + 0.25

Table S2. Raw Ct values (average + SEM) for PGC-1 and for each new PGC-1 target gene following treatment of C2C12 myotubes with 1 mM AICAR for 0, 6 or 24 h.

Gene / 0 h / 6 h / 24 h
Pgc-1α / 28.28 + 0.31 / 26.80 + 0.02 / 27.10 + 0.14
Akr1b10 / 28.32 + 0.49 / 28.93 + 0.17 / 28.72 + 0.23
Rmnd1 / 26.32 + 0.30 / 26.34 + 0.17 / 25.90 + 0.07
1110008P14Rik / 24.06 + 0.27 / 24.63 + 0.07 / 23.92 + 0.28
1700021F05Rik / 26.01 + 0.29 / 26.02 + 0.26 / 25.79 + 0.10
Mtfp1 / 31.21 + 0.21 / 30.74 + 0.06 / 30.81 + 0.06
Mrm1 / 28.75 + 0.13 / 28.46 + 0.05 / 28.30 + 0.03
Oxnad1 / 28.18 + 0.29 / 27.78 + 0.27 / 27.72 + 0.08
Cluh / 23.91 + 0.33 / 23.85 + 0.30 / 23.90 + 0.02

Table S3. Raw Ct values (average + SEM) for PGC-1 and ERR co-regulation of each new target gene following transduction of C2C12 myotubes with adenoviruses encoding GFP, PGC-1, siCON and siERR

Gene / GFP siCON / GFP siERR / PGC-1
siCON / PGC-1siERR
Akr1b10 / 29.95 + 0.19 / 29.30+ 0.11 / 27.20 + 0.29 / 27.87 +0.01
Rmnd1 / 24.59 + 0.05 / 24.60 + 0.08 / 23.25 + 0.21 / 24.42 +0.32
1110008P14Rik / 23.38 + 0.07 / 22.98 + 0.15 / 20.94 + 0.30 / 22.97 + 0.17
1700021F05Rik / 24.23+ 0.24 / 23.89+ 0.05 / 21.14 + 0.21 / 22.32 + 0.19
Mtfp1 / 27.64+ 0.09 / 27.96+ 0.02 / 25.60+ 0.14 / 26.82 + 0.22
Mrm1 / 28.68+ 0.27 / 28.74+ 0.14 / 25.55+ 0.36 / 27.73 + 0.23
Oxnad1 / 25.52+ 0.04 / 25.69 + 0.07 / 23.12 + 0.10 / 23.69 + 0.16
Cluh / 22.78 + 0.01 / 23.43 + 0.06 / 19.62 + 0.13 / 21.19 + 0.13

Table S4. Raw Ct values (average + SEM) of each new target gene following transduction of C2C12 myotubes with adenoviruses encoding a constitutively active form of ERR(VP-ERR) and its control VP16.

Gene / VP16 / VP-ERR
Akr1b10 / 30.23 + 0.64 / 28.51 + 0.17
Rmnd1 / 24.79 + 0.12 / 23.38 + 0.19
1110008P14Rik / 24.07+ 0.09 / 22.61 + 0.19
1700021F05Rik / 24.28 + 0.21 / 23.55 + 0.95
Mtfp1 / 28.67 + 0.53 / 26.15 + 0.53
Mrm1 / 29.89 + 0.95 / 27.71 + 0.53
Oxnad1 / 25.72 + 0.19 / 24.69 + 0.33
Cluh / 22.76 + 0.37 / 20.08 + 0.54