Table S1. Gene expression values (FPKM) of the transcripts in Control treatment by RNA Seq.

Locus tag / Seq. Description / Seq. Length / #GOs / GOs / FPKM
MmSR116_0004 / protein of unassigned function / 507 / 0 / - / 310,585
MmSR116_0006 / 3-hydroxyacyl- dehydrogenase / 2202 / 4 / F:3-hydroxyacyl-CoA dehydrogenase activity; P:oxidation-reduction process; P:fatty acid metabolic process; F:coenzyme binding / 134,955
MmSR116_0024 / protoheme ix farnesyltransferase / 951 / 4 / C:plasma membrane; C:integral to membrane; F:protoheme IX farnesyltransferase activity; P:heme O biosynthetic process / 258,54
MmSR116_0025 / cytochrome c oxidase subunit i / 1629 / 10 / F:cytochrome-c oxidase activity; F:heme binding; C:integral to membrane; P:aerobic respiration; F:electron carrier activity; F:iron ion binding; F:copper ion binding; P:electron transport chain; C:plasma membrane; P:transport / 441,442
MmSR116_0026 / cytochrome c oxidase subunit ii / 840 / 6 / C:integral to membrane; C:respiratory chain; F:cytochrome-c oxidase activity; F:copper ion binding; P:electron transport chain; / 205,365
MmSR116_0029 / glutamate synthase / 4716 / 3 / P:oxidation-reduction process; F:glutamate synthase activity; P:glutamate biosynthetic process / 36,4172
MmSR116_0030 / dihydropyrimidine dehydrogenase subunit a / 1434 / 5 / F:glutamate synthase (NADPH) activity; F:flavin adenine dinucleotide binding; F:iron-sulfur cluster binding; P:glutamate biosynthetic process; P:oxidation-reduction process / 211,236
MmSR116_0031 / cytoplasmic protein / 1434 / 1 / F:hydrolase activity / 91,999
MmSR116_0056 / atp-binding protein / 1029 / 2 / F:helicase activity; P:metabolic process / 175,289
MmSR116_0059 / family transcriptional regulator / 516 / 3 / P:regulation of transcription, DNA-dependent; F:DNA binding; F:zinc ion binding / 306,026
MmSR116_0060 / ---NA--- / 198 / 0 / - / 3372,86
MmSR116_0082 / 50s ribosomal protein l25 / 693 / 4 / C:ribosome; F:structural constituent of ribosome; F:5S rRNA binding; P:translation / 850,473
MmSR116_0085 / protein of unassigned function / 294 / 0 / - / 1037,74
MmSR116_0091 / serine hydroxymethyltransferase / 1305 / 4 / F:glycine hydroxymethyltransferase activity; P:glycine metabolic process; P:L-serine metabolic process; F:pyridoxal phosphate binding / 312,296
MmSR116_0097 / protein of unassigned function / 1302 / 0 / - / 103,1
MmSR116_0098 / family serine protein kinase / 1953 / 1 / F:protein kinase activity / 491,551
MmSR116_0099 / 4-aminobutyrate aminotransferase / 444 / 2 / F:transaminase activity; P:metabolic process / 449,94
MmSR116_0103 / 3-oxoacyl-(acyl-carrier-protein) synthase iii / 1008 / 2 / P:fatty acid biosynthetic process; F:3-oxoacyl-[acyl-carrier-protein] synthase activity / 187,66
MmSR116_0104 / fatty acid phospholipid synthesis protein / 1104 / 4 / P:fatty acid biosynthetic process; F:transferase activity, transferring acyl groups other than amino-acyl groups; P:oxidation-reduction process; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor / 153,336
MmSR116_0116 / 1-deoxy-d-xylulose-5-phosphate synthase / 1971 / 6 / F:magnesium ion binding; F:1-deoxy-D-xylulose-5-phosphate synthase activity; F:thiamine pyrophosphate binding; P:thiamine biosynthetic process; P:terpenoid biosynthetic process; P:1-deoxy-D-xylulose 5-phosphate biosynthetic process / 519,628
MmSR116_0130 / nad-dependent epimerase dehydratase / 2664 / 3 / F:oxidoreductase activity, acting on CH-OH group of donors; P:oxidation-reduction process; F:flavin adenine dinucleotide binding / 114,461
MmSR116_0131 / glycosyl transferase / 1050 / 1 / P:biosynthetic process / 173,38
MmSR116_0138 / endo- - -beta-glycanase / 885 / 2 / F:hydrolase activity, hydrolyzing O-glycosyl compounds; P:carbohydrate metabolic process / 157,672
MmSR116_0141 / membrane protein / 1638 / 2 / P:metabolic process; F:sulfuric ester hydrolase activity / 103,677
MmSR116_0145 / adenylate guanylate cyclase / 1260 / 3 / P:intracellular signal transduction; F:phosphorus-oxygen lyase activity; P:cyclic nucleotide biosynthetic process / 146,502
MmSR116_0146 / rna polymerase sigma factor / 1980 / 5 / P:regulation of transcription, DNA-dependent; F:DNA binding; F:sequence-specific DNA binding transcription factor activity; F:sigma factor activity; P:DNA-dependent transcription, initiation / 195,048
MmSR116_0151 / carbamoyl phosphate synthase large subunit / 3474 / 4 / P:nitrogen compound metabolic process; F:ATP binding; F:catalytic activity; F:metal ion binding / 44,3308
MmSR116_0153 / protein of unassigned function / 501 / 0 / - / 368,984
MmSR116_0157 / sulfite oxidase subunit / 951 / 2 / F:electron carrier activity; P:oxidation-reduction process / 191,291
MmSR116_0160 / aminopeptidase a / 1512 / 5 / F:metalloexopeptidase activity; F:aminopeptidase activity; F:manganese ion binding; C:cytoplasm; P:proteolysis / 310,502
MmSR116_0163 / organic solvent tolerance protein / 2580 / 3 / P:response to organic substance; C:outer membrane; P:membrane organization / 107,446
MmSR116_0166 / membrane protein / 975 / 0 / - / 693,353
MmSR116_0168 / dna-binding protein / 633 / 1 / F:DNA binding / 368,694
MmSR116_0177 / alpha beta hydrolase / 957 / 2 / P:metabolic process; F:hydrolase activity / 172,394
MmSR116_0180 / methyl-accepting chemotaxis sensory transducer with pas pac sensor / 1461 / 3 / C:membrane; P:phosphorelay signal transduction system; F:phosphorelay sensor kinase activity / 143,304
MmSR116_0184 / formaldehyde-activating enzyme / 513 / 6 / C:cytoplasm; F:carbon-nitrogen lyase activity; P:one-carbon metabolic process; P:response to toxic substance; P:carbohydrate biosynthetic process; P:formaldehyde catabolic process / 337,85
MmSR116_0187 / n -methenyltetrahydromethanopterin cyclohydrolase / 975 / 4 / C:cytoplasm; F:methenyltetrahydromethanopterin cyclohydrolase activity; P:one-carbon metabolic process; P:formaldehyde catabolic process / 417,02
MmSR116_0189 / methylene-tetrahydromethanopterin dehydrogenase / 894 / 5 / C:cytoplasm; F:oxidoreductase activity; P:one-carbon metabolic process; P:formaldehyde catabolic process; P:oxidation-reduction process / 241,524
MmSR116_0191 / tungsten-containing formylmethanofuran dehydrogenase subunit b / 1107 / 1 / P:one-carbon metabolic process / 187,717
MmSR116_0192 / formylmethanofuran dehydrogenase subunit a / 1647 / 6 / C:cytoplasm; F:transferase activity; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; F:metal ion binding; P:one-carbon metabolic process; P:formaldehyde catabolic process / 193,359
MmSR116_0199 / pyrroloquinoline quinone biosynthesis protein / 900 / 3 / F:hydrolase activity; P:transport; P:pyrroloquinoline quinone biosynthetic process / 503,502
MmSR116_0200 / pyrroloquinoline quinone biosynthesis protein / 1086 / 3 / P:pyrroloquinoline quinone biosynthetic process; P:oxidation-reduction process; F:quinone binding / 153,141
MmSR116_0201 / pyrroloquinoline quinone biosynthesis protein / 1146 / 4 / F:catalytic activity; P:pyrroloquinoline quinone biosynthetic process; F:4 iron, 4 sulfur cluster binding; F:metal ion binding / 143,361
MmSR116_0202 / protein of unassigned function / 723 / 0 / - / 184,256
MmSR116_0207 / abc transporter substrate-binding protein / 849 / 2 / P:transport; F:transporter activity / 391,152
MmSR116_0208 / cytochrome c / 612 / 2 / F:heme binding; F:electron carrier activity / 860,565
MmSR116_0209 / methanol dehydrogenase / 1806 / 5 / F:oxidoreductase activity, acting on CH-OH group of donors; F:calcium ion binding; P:oxidation-reduction process; C:membrane; C:outer membrane-bounded periplasmic space / 1776,7
MmSR116_0219 / malic enzyme / 2331 / 8 / F:malate dehydrogenase (decarboxylating) activity; F:NAD binding; P:oxidation-reduction process; C:cytosol; F:malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity; F:manganese ion binding; P:malate metabolic process; F:transferase activity, transferring acyl groups / 158,371
MmSR116_0222 / polyphosphate kinase / 2403 / 3 / P:polyphosphate biosynthetic process; C:polyphosphate kinase complex; F:polyphosphate kinase activity / 156,111
MmSR116_0236 / glutamyl-trna amidotransferase subunit b / 1473 / 1 / F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor / 266,398
MmSR116_0241 / cell wall assembly protein / 591 / 0 / - / 453,747
MmSR116_0245 / multifunctional complex type / 1305 / 3 / F:dihydroorotase activity; F:metal ion binding; P:pyrimidine nucleotide biosynthetic process / 121,803
MmSR116_0252 / 5 -methylthioadenosine phosphorylase / 876 / 3 / P:nucleoside metabolic process; F:phosphorylase activity; F:S-methyl-5-thioadenosine phosphorylase activity / 232,145
MmSR116_0253 / cytochrome c1 / 897 / 6 / F:iron ion binding; F:ubiquinol-cytochrome-c reductase activity; F:electron carrier activity; F:heme binding; P:oxidation-reduction process; / 425,514
MmSR116_0254 / cytochrome b / 1287 / 4 / F:oxidoreductase activity; F:electron carrier activity; C:membrane; P:respiratory electron transport chain / 379,906
MmSR116_0261 / succinate hydrophobic membrane anchor protein / 420 / 4 / F:succinate dehydrogenase activity; P:tricarboxylic acid cycle; C:integral to membrane; F:heme binding / 475,388
MmSR116_0268 / gmp synthase / 1557 / 4 / P:GMP biosynthetic process; F:ATP binding; F:GMP synthase (glutamine-hydrolyzing) activity; F:pyrophosphatase activity / 151,556
MmSR116_0282 / dna repair atpase / 2082 / 0 / - / 71,1938
MmSR116_0291 / Hypothetical protein / 1572 / 0 / - / 70,2084
MmSR116_0316 / cytochrome c / 864 / 3 / C:cytochrome complex; F:electron carrier activity; F:heme binding / 267,797
MmSR116_0318 / sulfur oxidation protein / 471 / 0 / - / 277,859
MmSR116_0336 / transcriptional initiation protein tat / 771 / 0 / - / 148,066
MmSR116_0349 / protein of unassigned function / 1722 / 0 / - / 175,285
MmSR116_0366 / metallophosphoesterase / 579 / 1 / F:hydrolase activity / 291,82
MmSR116_0367 / integrase family protein / 1662 / 3 / P:DNA recombination; P:DNA integration; F:DNA binding / 255,201
MmSR116_0371 / cation transporter / 1551 / 2 / P:transmembrane transport; C:membrane / 167,794
MmSR116_0394 / atpase / 1875 / 4 / P:phosphorylation; F:phosphorelay sensor kinase activity; P:signal transduction; C:membrane / 100,699
MmSR116_0414 / short-chain dehydrogenase / 768 / 2 / F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; P:oxidation-reduction process / 252,054
MmSR116_0419 / metal-chelation protein chad / 1515 / 0 / - / 121,551
MmSR116_0423 / gdsl family lipase / 804 / 2 / F:hydrolase activity; P:metabolic process / 276,692
MmSR116_0431 / histidine kinase / 1809 / 4 / P:phosphorylation; F:phosphorelay sensor kinase activity; P:signal transduction; C:integral to membrane / 99,6872
MmSR116_0433 / pyridoxamine 5 -phosphate oxidase / 780 / 3 / P:oxidation-reduction process; F:FMN binding; F:oxidoreductase activity / 178,108
MmSR116_0440 / molybdenum cofactor biosynthesis protein / 1230 / 1 / P:Mo-molybdopterin cofactor biosynthetic process / 171,653
MmSR116_0442 / indole-3-glycerol-phosphate synthase / 918 / 2 / F:indole-3-glycerol-phosphate synthase activity; P:tryptophan metabolic process / 205,289
MmSR116_0446 / #NAME? / 1980 / 1 / F:isomerase activity / 59,9646
MmSR116_0450 / ctp synthetase / 1629 / 4 / F:CTP synthase activity; F:ATP binding; P:glutamine metabolic process; P:'de novo' CTP biosynthetic process / 93,1682
MmSR116_0457 / cobaltochelatase subunit / 3384 / 1 / P:biosynthetic process / 59,5735
MmSR116_0459 / precorrin-8x methylmutase / 693 / 2 / F:precorrin-8X methylmutase activity; P:cobalamin biosynthetic process / 295,793
MmSR116_0471 / abc transporter / 822 / 2 / F:ATPase activity; F:ATP binding / 265,904
MmSR116_0485 / upf0133 protein / 324 / 3 / C:cytoplasm; C:bacterial nucleoid; F:DNA binding / 1001,89
MmSR116_0486 / phosphoenolpyruvate carboxykinase / 1620 / 3 / P:gluconeogenesis; F:ATP binding; F:phosphoenolpyruvate carboxykinase (ATP) activity / 298,109
MmSR116_0490 / trna pseudouridine synthase a / 759 / 3 / F:RNA binding; F:pseudouridine synthase activity; P:pseudouridine synthesis / 272,634
MmSR116_0491 / membrane protein / 1380 / 0 / - / 123,061
MmSR116_0493 / amylo-alpha- -glucosidase / 2346 / 6 / C:integral to membrane; F:glucosylceramidase activity; P:sphingolipid metabolic process; P:glycogen catabolic process; F:amylo-alpha-1,6-glucosidase activity; F:4-alpha-glucanotransferase activity / 74,4856
MmSR116_0494 / glycosyl transferase / 1131 / 1 / P:biosynthetic process / 1070,81
MmSR116_0498 / phenylalanyl-trna synthetase subunit beta / 2421 / 7 / F:ATP binding; F:magnesium ion binding; P:phenylalanyl-tRNA aminoacylation; F:phenylalanine-tRNA ligase activity; F:tRNA binding; P:tRNA processing; C:cytoplasm / 216,765
MmSR116_0501 / translation initiation factor if-3 / 522 / 2 / P:translational initiation; F:translation initiation factor activity / 288,892
MmSR116_0504 / alpha beta hydrolase / 768 / 2 / F:hydrolase activity; P:metabolic process / 255,655
MmSR116_0508 / tat pathway signal protein / 474 / 0 / - / 368,095
MmSR116_0510 / biopolymer transporter / 492 / 3 / C:integral to membrane; F:transporter activity; P:protein transport / 341,665
MmSR116_0524 / acyltransferase 3 / 1071 / 1 / F:transferase activity, transferring acyl groups other than amino-acyl groups / 237,649
MmSR116_0528 / thiamine biosynthesis protein / 1887 / 2 / P:thiamine biosynthetic process; F:iron-sulfur cluster binding / 235,086
MmSR116_0530 / glutamine amidotransferase / 825 / 4 / F:transferase activity; F:hydrolase activity; F:ligase activity; P:glutamine metabolic process / 1157,48
MmSR116_0531 / asparagine synthase / 1770 / 2 / P:asparagine biosynthetic process; F:asparagine synthase (glutamine-hydrolyzing) activity / 96,3162
MmSR116_0538 / radical sam protein / 1047 / 4 / F:catalytic activity; F:metal ion binding; F:4 iron, 4 sulfur cluster binding; P:metabolic process / 269,066
MmSR116_0542 / polyphosphate kinase / 846 / 2 / F:polyphosphate kinase activity; P:phosphorus metabolic process / 505,531
MmSR116_0545 / poly(3-hydroxybutyrate) depolymerase / 2358 / 0 / - / 66,756
MmSR116_0556 / family transcriptional regulator / 900 / 2 / P:regulation of transcription, DNA-dependent; F:sequence-specific DNA binding transcription factor activity / 268,548
MmSR116_0557 / citrate transporter / 1323 / 4 / P:transmembrane transport; C:integral to membrane; F:citrate transmembrane transporter activity; P:citrate transport / 186,467
MmSR116_0565 / coenzyme a transferase / 1983 / 2 / F:3-oxoacid CoA-transferase activity; P:metabolic process / 178,198
MmSR116_0572 / membrane protein / 612 / 0 / - / 343,289
MmSR116_0574 / murein transglycosylase / 795 / 2 / F:transferase activity, transferring glycosyl groups; P:metabolic process / 858,907
MmSR116_0584 / atpase aaa / 1941 / 3 / P:proteolysis; F:metalloendopeptidase activity; F:ATP binding / 93,8581
MmSR116_0586 / Hypothetical protein / 1029 / 0 / - / 177,346
MmSR116_0598 / cation transporter / 1344 / 2 / P:transmembrane transport; C:membrane / 189,59
MmSR116_0599 / cation transporter / 3249 / 3 / P:cation transport; F:cation transmembrane transporter activity; C:integral to membrane / 49,8084
MmSR116_0637 / arsenic transporter / 1068 / 5 / C:integral to membrane; F:inorganic anion transmembrane transporter activity; P:transmembrane transport; P:sodium ion transport; F:bile acid:sodium symporter activity / 220,25
MmSR116_0672 / integral membrane sensor signal transduction histidine kinase / 1317 / 5 / C:integral to membrane; F:phosphorelay sensor kinase activity; F:ATP binding; P:phosphorelay signal transduction system; P:signal transduction by phosphorylation / 134,501
MmSR116_0683 / piwi domain-containing protein / 2304 / 2 / F:protein binding; F:nucleic acid binding / 64,1243
MmSR116_0688 / dna gyrase subunit b / 2445 / 5 / F:ATP binding; P:DNA topological change; F:DNA binding; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; C:chromosome / 407,807
MmSR116_0689 / aldo keto reductase / 963 / 2 / P:oxidation-reduction process; F:oxidoreductase activity / 184,636
MmSR116_0696 / protein of unassigned function / 636 / 0 / - / 1227,12
MmSR116_0697 / polysaccharide export protein / 588 / 3 / F:polysaccharide transmembrane transporter activity; P:polysaccharide transport; C:membrane / 275,648
MmSR116_0698 / lipopolysaccharide biosynthesis protein / 2235 / 2 / P:lipopolysaccharide biosynthetic process; C:membrane / 153,135
MmSR116_0709 / protein of unassigned function / 639 / 0 / - / 226,401
MmSR116_0710 / multidrug abc transporter permease / 858 / 4 / C:membrane; F:ATPase activity, coupled to transmembrane movement of substances; P:transport; F:ATP binding / 265,624