Garlic
(Allium sativum) / Fungi (MIC) / Bacteria (MIC) / References
Extract / C. albicans(8.9 mg/mL) / S. aureus (71.4mg/mL) / 1
E. faecalis (71.4mg/mL) / 1
P. gingivalis (4.4mg/mL) / 1
Allicin / C. albicans (3.4µg/mL) / S. aureus (27.5µg/mL) / 1
E. faecalis (27.5µg/mL) / 1
P. gingivalis (1.7µg/mL) / 1
Extract / C. albicans (0.8-1.6mg/mL) / 2
Allicin / C. parapsilosis (0.15µg/mL) / P. aeruginosa (>100µg/mL) / 3
C. tropicalis (0.3µg/mL) / E. coli (15µg/mL) / 3
C. krusei (0.3µg/mL) / S. aureus (15µg/mL) / 3
Extract / S. aureus(161mg/mL) / 4
P. aeruginosa(134 mg/mL) / 4
Extract / C. albicans (0.29 mg/mL) / 5
Extract / P. aeruginosa(15mg/mL) / 6
S. aureus (9mg/mL) / 6
E.coli(18mg/mL) / 6
Extract / C. albicans(16mg/mL) / E. faecalis (128mg/mL) / 7
Oil / P. aeruginosa(16mg/mL) / 8
Allicin / P. aeruginosa ( >512µg/ml) / 9
Alliumin protein / M. arachidicola (1.5µM) / P. fluorescens(Not given) / 10
Allivin protein / M. arachidicola(1.6µM) / 11
B. cinerea (1.6 µM) / 11
ASL50 protein / C. parapsilosis (10µg/mL) / P. aeruginosa ( 80µg/ml) / Present
C. tropicalis (20µg/mL)
C. krusei (40µg/mL)
C. glabrata (40µg/mL)

Table. S1. Comparative study of MIC value of garlic products against microbes.

References

1.  I.M. Bakri, C.W. Douglas, Inhibitory effect of garlic extract on oral bacteria, Arch Oral Biol 50 (2005) 645-651.

2.  M.A. Ghannoum, Studies on the anticandidal mode of action of Allium sativum (garlic), J Gen Microbiol 134 (1988) 2917-2924.

3.  S. Ankri, D. Mirelman, Antimicrobial properties of allicin from garlic, Microbes Infect 1 (1999) 125-129.

4.  J.A.Alli,B.E. Boboye, I.O. Okonko, A.F. Kolade, J.C. Nwanze, In-vitro assessments of the effects of garlic (Allium sativum) extract on clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus, Advances in Applied Science Research 2 (4) (2011) 25-36.

5.  K.M. Lemar, M.P. Turner, D. Lloyd, Garlic (Allium sativum) as an anti-Candida agent: a comparison of the efficacy of fresh garlic and freeze-dried extracts, J ApplMicrobiol 93 (2002) 398-405.

6.  D. Srinivasan, S.Srinivasan, P. Lakshmanaperumalsamy, In vitro Antibacterial Activity and Stability of Garlic Extract at Different pH and Temperature, Electronic Journal of Biology 5(1)(2009) 5-10.

7.  H. J. Leea, H. S. Parkb, K. H. Kimc, T. Y. Kwond, S. H.Honge, Effect of garlic on bacterial biofilm formation on orthodontic wire, Angle Orthodontist 81 (2011) 5.

8.  S. Tsao, M. Yin, In vitro activity of garlic oil and four diallylsulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiellapneumoniae, J AntimicrobChemother 47 (2001) 665-670.

9.  Y. Cai, R. Wang, F. Pei, B.B. Liang, Antibacterial activity of allicin alone and in combination with beta-lactams against Staphylococcus spp. and Pseudomonas aeruginosa, J Antibiot (Tokyo) 60 (2007) 335-338.

10.  L. Xia, T.B. Ng, Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs, Peptides 26(2005) 177-183.

11.  H.X. Wang, T.B. Ng, Purification of allivin, a novel antifungal protein from bulbs of the round cloved garlic, Life Sci 70(2001) 357-365.