Table 3S Immune System Genes Not Identified As Disease Genes

Table 3S Immune system genes not identified as disease genes.

Symbol / Accession Number / LocusLink Name
MAP3K14 / NM_003954 / mitogen-activated protein kinase kinase kinase 14
CX3CL1 / NM_002996 / chemokine (C-X3-C motif) ligand 1
CD79B / NM_000626 / CD79B antigen (immunoglobulin-associated beta)
MASP2 / NM_006610 / mannan-binding lectin serine protease 2
CD4 / NM_000616 / CD4 antigen (p55)
TYROBP / NM_003332 / TYRO protein tyrosine kinase binding protein
CLDN11 / NM_005602 / claudin 11 (oligodendrocyte transmembrane protein)
CD6 / NM_006725 / CD6 antigen
NR1H3 / NM_005693 / nuclear receptor subfamily 1, group H, member 3
TNFRSF1B / NM_001066 / tumor necrosis factor receptor superfamily, member 1B
LY75 / NM_002349 / lymphocyte antigen 75
TCF3 / NM_003200 / transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
NFATC3 / NM_173165 / nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PTGS2 / NM_000963 / prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SART3 / NM_014706 / squamous cell carcinoma antigen recognised by T cells 3
EDN1 / NM_001955 / endothelin 1
TAP2 / NM_000544 / transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
CXCL2 / NM_002089 / chemokine (C-X-C motif) ligand 2
TCF7 / NM_003202 / transcription factor 7 (T-cell specific, HMG-box)
FYB / NM_001465 / FYN binding protein (FYB-120/130)
OPRK1 / NM_000912 / opioid receptor, kappa 1
MMP2 / NM_004530 / matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
SH3BP2 / NM_003023 / SH3-domain binding protein 2
ATRN / NM_139321 / attractin
PTPN11 / NM_002834 / protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
AARS / NM_001605 / alanyl-tRNA synthetase
ITGA6 / NM_000210 / integrin, alpha 6
TGFB2 / NM_003238 / transforming growth factor, beta 2
IL11 / NM_000641 / interleukin 11
NCR3 / NM_147130 / natural cytotoxicity triggering receptor 3
MAPK1 / NM_138957 / mitogen-activated protein kinase 1
BDKRB1 / NM_000710 / bradykinin receptor B1
MMP9 / NM_004994 / matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
NFATC2 / NM_173091 / nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
JAG1 / NM_000214 / jagged 1 (Alagille syndrome)
CCL22 / NM_002990 / chemokine (C-C motif) ligand 22
CCL17 / NM_002987 / chemokine (C-C motif) ligand 17
MEFV / NM_000243 / Mediterranean fever
B7H3 / NM_025240 / B7 homolog 3
IKBKB / AF080158 / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL7 / NM_000880 / interleukin 7
PDE7A / NM_002603 / phosphodiesterase 7A
CALR / NM_004343 / calreticulin
PBEF / NM_005746 / pre-B-cell colony-enhancing factor
VIPR2 / NM_003382 / vasoactive intestinal peptide receptor 2
GATA3 / NM_002051 / GATA binding protein 3
CXCL12 / NM_000609 / chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
MAPK8 / NM_139049 / mitogen-activated protein kinase 8
CSF3 / NM_000759 / colony stimulating factor 3 (granulocyte)
PFN1 / NM_005022 / profilin 1
C1QBP / NM_001212 / complement component 1, q subcomponent binding protein
MAP2K6 / NM_002758 / mitogen-activated protein kinase kinase 6
VTN / NM_000638 / vitronectin (serum spreading factor, somatomedin B, complement S-protein)
AREG / NM_001657 / amphiregulin (schwannoma-derived growth factor)
IL2 / NM_000586 / interleukin 2
CTSC / NM_001814 / cathepsin C
HPX / NM_000613 / hemopexin
MDK / NM_002391 / midkine (neurite growth-promoting factor 2)
TCIRG1 / NM_006019 / T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a isoform 3
IL23A / NM_016584 / interleukin 23, alpha subunit p19
LNK / NM_005475 / lymphocyte adaptor protein
IFNG / NM_000619 / interferon, gamma
ACRBP / NM_032489 / acrosin binding protein
HEF1 / NM_006403 / MISSING
TNF / NM_022490 / tumor necrosis factor (TNF superfamily, member 2)
OPRM1 / NM_000914 / opioid receptor, mu 1
MAPK14 / NM_139012 / mitogen-activated protein kinase 14
IL17 / NM_002190 / interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
IL12B / NM_002187 / interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
IL5 / NM_000879 / interleukin 5 (colony-stimulating factor, eosinophil)
NR3C1 / NM_000176 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
BCL6 / NM_138931 / B-cell CLL/lymphoma 6 (zinc finger protein 51)
CD86 / NM_175862 / CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
HES1 / NM_005524 / hairy and enhancer of split 1, (Drosophila)
IL1A / NM_000575 / interleukin 1, alpha
CCL20 / NM_004591 / chemokine (C-C motif) ligand 20
ITGB6 / NM_000888 / integrin, beta 6
ITGA4 / NM_000885 / integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
DOK1 / NM_001381 / docking protein 1, 62kDa (downstream of tyrosine kinase 1)
TACR1 / NM_001058 / tachykinin receptor 1
IL1R1 / NM_000877 / interleukin 1 receptor, type I
IL18R1 / NM_003855 / interleukin 18 receptor 1
IL18RAP / NM_003853 / interleukin 18 receptor accessory protein
ATF2 / NM_001880 / activating transcription factor 2
CD2 / NM_001767 / CD2 antigen (p50), sheep red blood cell receptor
BY55 / NM_007053 / natural killer cell receptor, immunoglobulin superfamily member
F3 / NM_001993 / coagulation factor III (thromboplastin, tissue factor)
TNFSF6 / NM_000639 / tumor necrosis factor (ligand) superfamily, member 6
TNFSF4 / NM_003326 / tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)
SERPINC1 / NM_000488 / serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
CSF3R / NM_156039 / colony stimulating factor 3 receptor (granulocyte)
TNFRSF8 / NM_001243 / tumor necrosis factor receptor superfamily, member 8
CD80 / NM_005191 / CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
ADORA3 / NM_000677 / adenosine A3 receptor
CD244 / NM_016382 / natural killer cell receptor 2B4
AIF1 / NM_001623 / allograft inflammatory factor 1
IL1B / NM_000576 / interleukin 1, beta
IRF3 / NM_001571 / interferon regulatory factor 3
MASP1 / NM_139125 / mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)
ZFP36 / NM_003407 / zinc finger protein 36, C3H type, homolog (mouse)
ADORA2A / NM_000675 / adenosine A2a receptor
IRF5 / NM_002200 / interferon regulatory factor 5
NEDD8 / NM_006156 / neural precursor cell expressed, developmentally down-regulated 8
EIF2S3 / NM_001415 / eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
RAF1 / NM_002880 / v-raf-1 murine leukemia viral oncogene homolog 1
PPARG / NM_015869 / peroxisome proliferative activated receptor, gamma
IGHMBP2 / NM_002180 / immunoglobulin mu binding protein 2
AP3B1 / NM_003664 / adaptor-related protein complex 3, beta 1 subunit
ALOX5AP / NM_001629 / arachidonate 5-lipoxygenase-activating protein
GRB2 / NM_002086 / growth factor receptor-bound protein 2
IL2RA / NM_000417 / interleukin 2 receptor, alpha
IL15RA / NM_002189 / interleukin 15 receptor, alpha
TPP2 / NM_003291 / tripeptidyl peptidase II
GCNT1 / NM_001490 / glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
ANXA1 / NM_000700 / annexin A1
NT5E / NM_002526 / 5'-nucleotidase, ecto (CD73)
AGT / NM_000029 / angiotensinogen (serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8)
IL10 / NM_000572 / interleukin 10
CCL21 / NM_002989 / chemokine (C-C motif) ligand 21
CD72 / NM_001782 / CD72 antigen
IER3 / NM_052815 / immediate early response 3
MOG / NM_002433 / myelin oligodendrocyte glycoprotein
IL18BP / NM_005699 / interleukin 18 binding protein
IL21 / NM_021803 / interleukin 21
TCF12 / NM_003205 / transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)
KIF2C / NM_006845 / kinesin family member 2C
S100A8 / NM_002964 / S100 calcium binding protein A8 (calgranulin A)
HSPD1 / NM_002156 / heat shock 60kDa protein 1 (chaperonin)
IL9 / NM_000590 / interleukin 9
HDAC2 / NM_001527 / histone deacetylase 2
CXCR3 / NM_001504 / chemokine (C-X-C motif) receptor 3
CRH / NM_000756 / corticotropin releasing hormone
SEMA4D / NM_006378 / sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SCGB1A1 / NM_003357 / secretoglobin, family 1A, member 1 (uteroglobin)
SERPING1 / NM_000062 / serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
PTPRJ / NM_002843 / protein tyrosine phosphatase, receptor type, J
ITGB1 / NM_033667 / integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
VEGFC / NM_005429 / vascular endothelial growth factor C
DNAM-1 / NM_006566 / adhesion glycoprotein
IL18 / NM_001562 / interleukin 18 (interferon-gamma-inducing factor)
CCL28 / NM_148672 / chemokine (C-C motif) ligand 28
RUNX1 / NM_001754 / runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
TFF2 / NM_005423 / trefoil factor 2 (spasmolytic protein 1)
IL6R / NM_000565 / interleukin 6 receptor
CUTL1 / NM_181552 / cut-like 1, CCAAT displacement protein (Drosophila)
ALOX15 / NM_001140 / arachidonate 15-lipoxygenase
TNFSF12 / NM_003809 / tumor necrosis factor (ligand) superfamily, member 12
VCAM1 / NM_001078 / vascular cell adhesion molecule 1
TLR5 / NM_003268 / toll-like receptor 5
TOSO / NM_005449 / regulator of Fas-induced apoptosis
REL / NM_002908 / v-rel reticuloendotheliosis viral oncogene homolog (avian)
CCR1 / NM_001295 / chemokine (C-C motif) receptor 1
SCYE1 / NM_004757 / small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
IL15 / NM_172174 / interleukin 15
F2RL1 / NM_005242 / coagulation factor II (thrombin) receptor-like 1
DEFB1 / NM_005218 / defensin, beta 1
TRDV2 / X15207 / T cell receptor delta variable 2
IL17E / NM_022789 / interleukin 17E
RAG1 / NM_000448 / recombination activating gene 1
CRK / NM_016823 / v-crk sarcoma virus CT10 oncogene homolog (avian)
8D6A / NM_016579 / 8D6 antigen
PNOC / NM_006228 / prepronociceptin
TAP1 / NM_000593 / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
PSMB8 / NM_148919 / proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7)
AGER / NM_001136 / advanced glycosylation end product-specific receptor
GBX2 / NM_001485 / gastrulation brain homeo box 2
IL12A / NM_000882 / interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
LTB4R / NM_181657 / leukotriene B4 receptor
CD2BP2 / NM_006110 / CD2 antigen (cytoplasmic tail) binding protein 2
UMOD / NM_003361 / uromodulin (uromucoid, Tamm-Horsfall glycoprotein)
PTAFR / NM_000952 / platelet-activating factor receptor
SPN / NM_003123 / sialophorin (gpL115, leukosialin, CD43)
LAT / NM_014387 / linker for activation of T cells
ADORA2B / NM_000676 / adenosine A2b receptor
CD14 / NM_000591 / CD14 antigen
FPRL1 / NM_001462 / formyl peptide receptor-like 1
HRH1 / NM_000861 / histamine receptor H1
ALK / NM_004304 / anaplastic lymphoma kinase (Ki-1)
PTGER4 / NM_000958 / prostaglandin E receptor 4 (subtype EP4)
P2RY6 / NM_176798 / pyrimidinergic receptor P2Y, G-protein coupled, 6
C3AR1 / NM_004054 / complement component 3a receptor 1
CD8B1 / NM_004931 / CD8 antigen, beta polypeptide 1 (p37)
CCR3 / NM_178329 / chemokine (C-C motif) receptor 3
IL16 / NM_172217 / interleukin 16 (lymphocyte chemoattractant factor)
CCL19 / NM_006274 / chemokine (C-C motif) ligand 19
HPSE / NM_006665 / heparanase
LTA / NM_000595 / lymphotoxin alpha (TNF superfamily, member 1)
BAT1 / NM_080598 / HLA-B associated transcript 1
CD7 / NM_006137 / CD7 antigen (p41)
TLR1 / NM_003263 / toll-like receptor 1
TRAF6 / NM_145803 / TNF receptor-associated factor 6
CLC_2 / NM_013246 / MISSING
SPHK1 / NM_021972 / sphingosine kinase 1
GPR2 / NM_016602 / G protein-coupled receptor 2
KCNA3 / NM_002232 / potassium voltage-gated channel, shaker-related subfamily, member 3
CD19 / NM_001770 / CD19 antigen
PRF1 / NM_005041 / perforin 1 (pore forming protein)
F2R / NM_001992 / coagulation factor II (thrombin) receptor
PENK / NM_006211 / proenkephalin
TNFSF15 / NM_005118 / tumor necrosis factor (ligand) superfamily, member 15