Tab.S2: Effects of injury and feeding conditions on mRNA expression in the siphon-tissue ofsmall and largeL. ellipticaindividuals. After laboratory acclimation, individuals were kept under 23 days of “food” and “starvation” conditions and acute (2 days since infliction) injury, as well as 44 days of “food” and “starvation” and recovering from the previous inflicted injury. Data were measured by real-time PCR and normalized using 18s ribosomal RNA as the reference. Significant effects between groups (N=3-10) and interactions were analyized by two-way-ANOVA or non-parametric PERMANOVA (“adonis”) and are highlighted by *** (p<0.001), ** (p<0.01) and * (p<0.5). N.s. = not significant.All data showed a normal distribution and homogeneity in variance with two exceptions:# no equal variance, ## not normally distributed. See material and methods for detailed description of statistical analysis.

Small Individuals / Large Individuals
Treatment / Gene / Treatment / Time / Interaction / Treatment / Time / Interaction
Injury upon starvation / Le-TIMP / n.s. / * / n.s. / n.s. / *** / n.s.
Le-SOD / n.s. / ** / n.s. / *** / ** / **
Le-HSP / n.s. / * / n.s. / n.s. / *** / n.s.
Le-Catalase / n.s. / *** / n.s. / n.s. / *** / n.s.
Le-Chitinase / n.s. / * / n.s. / n.s. / ** / n.s.
Le-Actin / n.s. / ** / n.s. / n.s. / *** / n.s.
Le-Theromacin / n.s. / n.s. / n.s. / n.s. / n.s. / n.s.
Injury upon feeding / Le-TIMP / n.s. / *** / * / n.s. / ** / n.s.
Le-SOD / n.s. / ** / n.d. / n.s. / * / n.s.
Le-HSP / n.s. / n.s. / n.d. / n.s. / *** / n.s.
Le-Catalase / n.s. / *** / * / n.s. / ** / n.s.
Le-Chitinase / n.s. / n.s. / n.s. / * / ** / n.s.
Le-Actin / n.s. / * / ** / n.s. / ** / n.s.
Le-Theromacin / n.s. / n.s. / n.s. / n.s. / n.s. / n.s.
Feeding conditions / Le-TIMP / n.s. / *** / n.s. / n.s. / *** / n.s.
Le-SOD # / n.s. / *** / n.s. / n.s. / n.s. / n.s.
Le-HSP / ** / ** / n.s. / n.s. / *** / n.s.
Le-Catalase / * / *** / n.s. / n.s. / *** / n.s.
Le-Chitinase ## / ** / n.s. / n.s. / n.s. / n.s. / n.s.
Le-Actin / n.s. / *** / n.s. / n.s. / *** / n.s.
Le-Theromacin / n.s. / n.s. / n.s. / n.s. / n.s. / n.s.