MICR 405(G)

VIROLOGY

Wendell L. French, Ph.D.Spring 2013

Office: Rm 232

Phone 298-1294

Email:

Office hours: Mon 11a.m.-12 p.m., Tue 10 a.m.-12 p.m., Wed 11 a.m.-12 p.m.

Lecture (Rm 234): Wed. 6:30-8:30 p.m.

Lab (Rm 234): Friday 9-10:50 a.m.

SYLLABUS SUBJECT TO CHANGE WITH NOTICE!

Textbooks and other materials:

Basic Virology by E. K.Wagner, M. J. Hewlett, D. C. Bloom, and D. Camerini. 3rd Edition, 2008. Blackwell Science, Publ.

Web site:

American Society for Microbiology:

Center for Disease Control:

WebCT: = instructions will be given later

Course description:

A study of the biological characteristics of animal, plant, and bacterial viruses and the viruses which cause disease.

Prerequesites: Bot 200, Micr 200, Zool 200

Exams and Grade Scale

Exam 150 pts.

Exam 250 pts.

Exam 350 pts.

Final Exam50 pts.

Lab Exam50 pts.

Lab Attendance 28 pts.

(2 pts. for each day present in lab)

Assignments 40 pts.

(10 pts. each)

Quizzes 20 pts.

Lab Exercises 50 pts.

(10 pts. each) ______

Total Points 388 pts.

UNDERGRAD GRADING SCALE

100-93% = A

92-90% = A-

89-87% = B+

86-83% = B

82-80% = B-

79-77% = C+

76-73% = C

72-70% = C-

69-67% = D+

66-63% = D

62-60% = D-

59% and below = F

GRAD GRADING SCALE

A = 95-100%

B = 85-94%

C = 75-84%

D = 65-74%

F = below 65%

Each exam may include short answer essay, fill-in-the-blanks, multiple choice, true false, or matching. Exam format will be discussed prior to each exam.

Lab exam: Information and format will be presented before the exam.

Assignments and unannounced/announced quizzes will be given throughout the semester.

Assignments: If you are not present in class the day the assignment is handed out, you

will receive a zero. If you are excused for your absence the day the

assignment is handed out, you will receive the assignment. Assignments

are usually given a week before each lecture exam. All assignments must

be submitted by the due date listed on the assignment instructions.

Unannounced/announced quizzes: If you are not present the day a quiz is given

(unannounced or announced), you will receive a

zero. If you are excused for your absence the day a

quiz is given, you will have the opportunity to take

the make-up quiz.

Make-up Exams: Make-up exams will only be given if you provide a valid excuse prior

to the absence or valid documentation after-the-fact.

Late Work Policy: Assignments and written reports (i.e., lab exercises) will be docked

10% of their final grade per day that they are late.

Attendance: In order to get the most out of your education, you are expected to attend

all lectures and labs and to be on time and stay for the entire class period. Attendance for a course such as this is critical to your understanding of the material. Attendance will be taken at the beginning of each class period in lecture as well as lab. Note that 2 unexcused laboratory absences willresult in an automatic failure of the course. An excused absence requires proper documentation: if you are sick, provide me with a doctor’s note; if there is a family death, provide me with appropriate funeral documentation. Undocumented absences are considered unexcused by the University. Any combination of two incidences of coming to lab late and/or leaving lab early will be considered and treated as an unexcused absence.

Lecture exams will cover material presented in the text and in lecture. Notes for lectures will be available on WebCT Vista after the completion of each lecture unit. Access to WebCT Vista is available at:

CHEATING AND PLAGIARISM WILL NOT BE TOLERATED.

Definition of Plagiarism

The faculty of the Department of Biological Sciences ascribes to a definition of plagiarism as expressed by V. E. McMillan in Writing Papers in the Biological Sciences (Bedford/St.Martin’s Press, New York, pg 16)

“Plagiarism is the theft of someone else’s words, work, or ideas. It includes such acts as (1) turning in a friend’s paper and saying it is yours; (2) using another person’s data or ideas without acknowledgement; (3) copying an author’s exact words and putting them in your paper without quotation marks; and (4) using wording that is very similar to that of the original source but passing it off as entirely your own even while acknowledging the source.”

This includes information in textbooks or laboratory manuals, honors and masters theses, all writing assignments, and images. The faculty of the Department attempt to monitor student writing assignments (essay exams, papers, laboratory reports, and other writing assignments or exercises) for incidence of plagiarism. If plagiarism is found, the faculty will discuss the situation with the student and indicate to the student the penalty for this academic dishonesty. Potential penalties include those cited in the academic dishonesty section of the WIU web page.

Students with Disabilities:

"In accordance with University policy and the Americans with Disabilities Act (ADA), academic accommodations may be made for any student who notifies the instructor of the need for an accommodation. For the instructor to provide the proper accommodation(s) you must obtain documentation of the need for an accommodation through Disability Resource Center (DRC) and provide it to the instructor. It is imperative that you take the initiative to bring such needs to the instructor's attention, as he/she is not legally permitted to inquire about such particular needs of students. Students who may require special assistance in emergency evacuations (i.e. fire, tornado, etc.) should contact the instructor as to the most appropriate procedures to follow in such an emergency. Contact Disability Resource Center at 298-2512 for additional services."

“Be Respectful” Policy: Be respectful in class. Please do not disturb other students by talking unnecessarily, reading the paper, passing notes, doing homework for another course, etc. during the class. PLEASE TURN OFF ALL CELL PHONES, BEEPERS, AND OTHER ELECTRONIC DEVICES DURING CLASS. If you repeatedly disturb the class with talking, your cell phone, etc., I will ask you to leave the class. Come to class on time and stay until the end. If you have a hard time hearing me, please don’t hesitate to ask me to talk louder, or move your seat as you need to be able to hear better.

It is the student’s responsibility to be familiar with the information (including required forms, definitions, and time lines) contained in the following university web sites. Each student should access these web sites and carefully read the information they contain, your instructors will hold you responsible for knowing this information. If you have questions about any of the information contained in the web sites, ask your instructor:

Department of Biological Sciences Policies:

Student Rights and Responsibilities:

Final Exam Policy:

Academic Integrity Policy:

Grade Appeals Policy:

STATE ACCREDITATION POLICY INFORMATION:

“In accordance with Illinois State Board of Education certification rules, all candidates seeking teacher certification are required by Western Illinois University to obtain a grade of “C” or better in all directed general education course, all core courses, and all courses in the option. Note: A “C- ” is below a “C”.” Please note: any secondary science teacher certification student wanting to see how this course is aligned with the State and National Standards should see their advisor and/or examine the Secondary Science Teacher Certification WesternOnline Advising site.

SEE NEXT PAGE FOR CLASS SCHEDULE.

VIROLOGY

MICR 405(G)

CLASS SCHEDULE

Instructor: Wendell L. French, Ph.D. Spring 2013

Date Topic Textbook Chps.

1/16Historical Aspects and Characteristics of VirusesUnit 1:

Ch. 1,2,3,4

1/18Lab: No Lab

1/23Structure and ClassificationUnit 2: Ch. 5

1/25Lab: Movie(Influenza [Spanish Flu) 1918]

1/30Structure and ClassificationUnit 2: Ch. 5

2/1Lab: General Concepts

2/6Virus Replication CycleUnit 3: Ch. 6

2/8Lab: Review of General Concepts

2/13Virology TechniquesUnit 4:Ch.9,10,11

2/15Lab: Exam 1

2/20Cellular Mechanisms Of Host CellsUnit 5: Ch. 13

Genetics of VirusesUnit 6: Ch. 22

2/22Lab: Characteristics and titer of phage T4 and T4r

2/27BacteriophageUnit 7: Ch. 6, 14

3/1Lab: Results for bacteriophage titer

Polymerase Chain Reaction (PCR)

3/6BacteriophageUnit 7: Ch. 16, 18

3/8Lab: Continuation of Polymerase Chain Reaction (PCR)

3/11-3/15 SPRING BREAK

3/20Viral Diseases: Effects On HostUnit 8: Ch.3,4,15

3/22Lab: Exam 2; Examine results of PCR

Lambda DNA restriction enzyme analysis

3/27Host Response to VirusesUnit 9: Ch. 7,8

Antiviral Agents and VaccinesUnit 10: Ch. 8

3/29Lab: Continuation of Lambda DNA restriction

enzyme analysis

4/3Replication of RNA Viruses: Positive-SenseUnit 11: Ch. 14

Replication of RNA Viruses: Negative-SenseUnit 12: Ch. 15

4/5Lab: Examine results of Lambda DNA restriction

enzyme analysis

4/10Replication of DNA VirusesUnit 13: Ch.16,17

Tumor VirusesUnit 14: Ch. 19

4/12Lab: Simulated Detection of HIV-1 by Western Blot

4/17Retroviruses: LentivirusUnit 15: Ch.19

4/19Lab: Exam 3; Results and Discussion for Simulated Detection

of HIV-1 by Western Blot

4/24Viral DiseasesUnit 16

4/26Lab: Lab Review

5/1Viral DiseasesUnit 16

5/3Lab: Lab exam

5/8Final Exam Wednesday, 6 – 7:50 P.M. Rm. 234

SYLLABUS SUBJECT TO CHANGE WITH NOTICE!