Syllabus: Human Metabolic Biochemistry
Syllabus: Human Metabolic Biochemistry
Unless otherwise stated, lecture is at 11 AM in Main Auditorium
Date / Topic / Lecturer / ReadingBlock I. Enzymes and Intermediary Metabolism (Part 1) – 11 Lectures, 34%
M, Nov. 30 / Enzymes I: Properties and Catalytic Mechanisms / Blake / Ch. 6
T, Dec. 1 / Enzymes II: Kinetics and Enzyme Inhibition / Blake / Ch. 6
W, Dec. 2 / Enzymes III: Regulation and Drug Design / Blake / Ch. 6, Box 26-2
Th, Dec. 3 / Metabolic Design / Franklin / Ch. 13
F, Dec. 4 / Glycolysis I / Franklin / Ch. 14
M, Dec. 7 / Glycolysis II / Franklin / Ch. 14
T, Dec. 8 / Gluconeogenesis / Blake / Ch. 15
W, Dec. 9 / Glycogen Metabolism / Blake / Ch. 15
Th, Dec. 10 / Pentose Phosphate Pathway / Blake / Ch. 15
F, Dec. 11 / Metabolism of other Sugars / Franklin / Ch. 15
S, Dec. 12 / Email of Last EC Quiz Questions Due by Noon
Su, Dec. 13 / Block 1 On-line Practice Quiz Available at Noon (until Noon on Monday, Dec 14th)
M, Dec. 14 / Regulation of Carbohydrate Metabolism (1 PM – 1:50 PM) / Blake / Ch. 15
M, Dec. 14 / Block 1 Review Session (2 – 2:50 PM) / Franklin and Blake
T, Dec. 15 / Block 1 Study Day
W, Dec. 16 / Biochemistry Block 1 Exam (9 AM - Noon)
Block II. Intermediary Metabolism (Part 2) – 13 Lectures, 39%
M, Jan. 4 / Pyruvate Dehydrogenase and CAC I / Blake / Ch. 16
T, Jan. 5 / Citric Acid Cycle II / Blake / Ch. 16
W, Jan. 6 / Oxidative Phosphorylation (9:45 AM – 10:45 AM) / Blake / Ch. 19
W, Jan. 6 / Lipid Metabolism I: Fatty Acids / Franklin / Ch. 17
Th, Jan. 7 / Lipid Metabolism II: Ketone Bodies & Triacylglycerol / Franklin / Ch. 21
F, Jan. 8 / Lipid Metabolism III: Steroid Biosynthesis / Blake / Ch. 21
M, Jan. 11 / Clinical Correlation: Dysmorphogenesis - Defects in Cholesterol Biosynthesis / Andersson / Ch. 21
T, Jan. 12 / Lipid Metabolism IV: More Cholesterol Metabolism / Franklin / Ch. 21
W, Jan. 13 / Lipid Metabolism V: Steroids and Bile Acids / Franklin / Ch. 23
F, Jan. 15 / Lipid Metabolism VI: Phospholipids, Sphingolipids and Eicosanoids (9:45 – 10:45 AM) / Franklin / Ch. 21, 23
F, Jan. 15 / Nitrogen Metabolism I: The Urea Cycle / Franklin / Ch. 18
M, Jan. 18 / No Class - Martin Luther King Day
T, Jan. 19 / Nitrogen Metabolism II: Amino Acid Degradation (9:45 – 10:45 AM) / Franklin / Ch. 18
T, Jan. 19 / Nitrogen Metablism III: Amino Acid Synthesis / Franklin / Ch. 22
W, Jan. 20 / Email of Last EC Quiz Questions Due at Noon
Th, Jan. 21 / On-line Practice Quiz Available at Noon (until Noon on Friday Jan 22nd)
F, Jan. 22 / Block 2 Review Session / Franklin and Blake
M, Jan. 25 / Biochemistry Block 2 Exam (9 AM - Noon)
Block III. Diabetes: A Metabolic Disease – 9 Lectures, 27%
W, Feb. 3 / Nucleotide Metabolism I / Franklin / Ch. 22
Th, Feb. 4 / Nucleotide Metabolism II / Franklin / Ch. 22
F, Feb. 5 / Nutrition Jeopardy / Franklin / Understanding Nutrition Chs 10-11
M, Feb. 8 / Alcoholism: A Metabolic Disease (9:45 – 10:45 AM) / Franklin / BMB, Ch 25
M, Feb. 8 / Clinical Correlation: Diabetes / Fonseca
T, Feb 9 / Diabetes I – Central Glucose Metabolism / Franklin / Ch. 23
W, Feb 10 / Diabetes II - Glycation / Li / Ch. 23
Th, Feb. 11 / Diabetes III – Effects of Diabetes / Franklin / Ch. 23
F, Feb. 12 / Diabetes IV – Genetic, Environment and Obesity / Franklin / Ch. 23
S, Feb. 13 / Email of Last EC Quiz Questions Due at Noon
W, Feb. 24 / On-line Practice Quiz Available at Noon (until Noon on Thursday Feb 25th)
F, Feb. 26 / Block 3 Review Session / Franklin and Li
M, Mar. 1 / Biochemistry Block 3 Exam (9 AM - Noon)