SWISS Investigative Team

Wiklund JAC2006-039 -1-

Online Supplemental Material

Supplemental E-Appendix 1. SWISS Investigative Team

Executive Committee: James F. Meschia, chair; Thomas G.

Brott, Robert D. Brown, Jr, Brett Kissela, John Hardy,

Stephen S. Rich. Statistical Center: WakeForestUniversity

School of Medicine, Winston-Salem, North Carolina. Stephen

S. Rich, director; W. Mark Brown. DNA Repository: Coriell

Institute for Medical Research, Camden, New Jersey. Judith Keen, PhD

director. Data and Site Management: Mayo

Clinical Trials Services, Rochester, Minnesota.

Hattie M. Hanert, RN, project manager;

Karen Hurtis, clinical research associate;

Lindsey DeGoey, clinical trails assistant;

Karen Johnson, regulatory affairs manager.

Wiklund JAC2006-039 -1-

Wiklund JAC2006-039 -1-

Centers and Investigators Listed by Proband

Enrollment as of May 2006

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1. Mayo Clinic, Rochester, Minnesota(probands enrolled,58): Principal investigator (PI): Robert D. Brown, Jr, MD; coordinator: Colleen S. Albers, RN.

2.University of Cincinnati, Cincinnati, Ohio(probands enrolled, 46): PI: Brett Kissela, MD; coordinator:Kathleen Alwell, RN.

3.University of Virginia Health System, Charlottesville,Virginia(probands enrolled, 45): PI: Bradford Worrall, MD, MSc; coordinator: David Chernawsky.

4. Mayo Clinic, Jacksonville, Florida(probands enrolled,44): PI: Thomas G. Brott, MD; coordinators: Alexa Richie, CRC; Dale Butler, CRC, Sothear Luke, CRC.

5. Shands HealthCare, affiliated with the University ofFlorida, Jacksonville, Florida(probands enrolled, 42):PI: Scott Silliman, MD; coordinators: Yvonne Douglas, Raam Sambandam.

6. Neurological Associates, Inc, Richmond, Virginia(probands enrolled, 35): PI: Francis McGee, Jr, MD;coordinator: Cherie Wampler.

7.Mercy Ruan Neurology Clinic, Des Moines, Iowa(probands enrolled, 34): PI: Michael Jacoby, MD;coordinator: Judi Greene, RN.

8. Main Line Health Stroke Program, Bryn Mawr,Pennsylvania(probands enrolled, 18): PI: Gary Friday,MD; coordinator: Angela Whittington-Smith, RN.

9. KaleidaStrokeCareCenter, MillardFillmoreGatesCircleHospital, Buffalo, New York(probands enrolled,15): PI: R. Ferguson, MD; coordinator: KathleenWrest, MLS.

10.University of Maryland, Baltimore, Maryland (probands enrolled, 14): PI: Steven Kittner, MD; coordinator:Mary J. Sparks.

11. LutherMidelfortHospital, Eau Claire,

Wisconsin(probands enrolled, 14): PI: Felix

Chukwudelunzu, MD;coordinator: Karen

Snobl, RN.

12. Centre Hospitalier Affilie Universitaire de Quebec,Quebec City, Province of Quebec, Canada(probandsenrolled, 14): PI: Ariane Mackey, MD; coordinators:Annette Hache, RN; Sophie Dube, RN.

13.Hospital of the University of Pennsylvania,

Philadelphia, Pennsylvania(probands enrolled, 12): PI:Scott Kasner, MD; coordinator: Mary Liz Desanto.

14. University of South Alabama, Mobile, Alabama(probands enrolled, 12): PI: Richard Zweifler, MD;coordinator: Kelli Boots.

15. MaineMedicalCenter, Portland, Maine(probandsenrolled, 12): PI: John Belden, MD; coordinator: DianeDiconzo-Fanning, RN.

16. Mayo Clinic, Scottsdale, Arizona(probands enrolled,12): PI: David W. Dodick, MD; coordinator: Erica L.Boyd, RN.

17. OhioStateUniversity, Columbus, Ohio(probandsenrolled, 12): PI: Andrew Slivka, MD; coordinator:Peggy Notestine, CCRC.

18. MetroHealthMedicalCenter, Cleveland, Ohio(probands enrolled, 11): PI: Joseph Hanna, MD;coordinators: Alice Liskay, RN; Bonni Kurtz.

19. WakeForestUniversitySchool of Medicine,

Winston-Salem, North Carolina(probands enrolled, 11):PI: David Lefkowitz, MD; coordinator: JeanSatterfield, RN.

20. Cleveland Clinic Florida, Weston, Florida(probandsenrolled, 10): PI: Virgilio Salanga, MD; coordinator:Mercy Lois-Valdez.

21. University of Iowa Hospital, Iowa City, Iowa(probandsenrolled, 10): PI: Patricia Davis, MD; coordinator: JeriSieren, RN.

22. Hôpital Charles LeMoyne, Greenfield Park, Province ofQuebec, Canada(probands enrolled, 10): PI: Leo Berger,MD; coordinators: Denise Racicot, Joanna Wai Ling Ma.

23. Stroke Prevention and Atherosclerosis Research Centre,London, Ontario, Canada(probands enrolled, 10): PI:David Spence, MD; coordinator: Rose Freitas.

24. University of Texas Southwestern Medical Center atDallas, Dallas, Texas(probands enrolled, 9): PI: Mark Johnson, MD;

coordinator: J. Greggory Wright, BS.

25. University of California, DavisSchool of Medicine,Sacramento, California(probands enrolled, 8): PI: PieroVerro, MD; coordinator: Jacqueline Wright.

26. IndianaUniversitySchool of Medicine, Indianapolis, Indiana(probands enrolled, 8): PI: Linda Williams, MD; coordinator: Kelley Faver, MS.

27. HelenHayesHospital, West Haverstraw, New York(probands enrolled, 8): PI: Laura Lennihan, MD;coordinator: Laura Tenteromano, RN.

28. WashingtonUniversitySchool of Medicine, St. Louis,Missouri(probands enrolled, 8): PI: Jin-Moo Lee, MD,PhD; coordinator: Denise Shearrer, RMA, BS, Julie Ruckmann.

.

29. University of Wisconsin, Madison, Wisconsin(probandsenrolled, 7): PI: Robert Dempsey, MD; coordinator:Pam Winne.

30. Marshfield Clinic, Marshfield, Wisconsin(probandsenrolled, 7): PI: Percy Karanjia, MD; coordinator: KathyMancl, CCRC, Rob Bohl, NP.

31. ThomasJeffersonUniversityHospital, Philadelphia,Pennsylvania(probands enrolled, 6): PI: Rodney Bell,MD; coordinator: Mary-Kathleen Nilson-Whitten.

.

32. University of California Los Angeles Stroke Center, LosAngeles, California(probands enrolled, 6): PI: JefferySaver, MD; coordinator: Jill Haines.

33. EastBay Region Associates in Neurology, Berkeley,California(probands enrolled, 6): PI: Brian Richardson, MD; coordinator: Lauren McCormick.

34. University of Utah Medical Center, Salt Lake City, Utah(probands enrolled, 6). PI: Elaine J. Skalabrin, MD: coordinator: Jolee Mougey, MPH.

35. University of Kentucky, Lexington, Kentucky(probandsenrolled, 5): PI: L. Creed Pettigrew, MD; coordinator:Deborah Taylor, MS.

36. Florida Neurovascular Institute, Tampa, Florida(probands enrolled, 5): PI: Erfan Albakri, MD;coordinators: Mary Katherine Taylor, ARNP; Anessa Hohns.

37. Scripps Clinic, La Jolla, California(probands enrolled,4): PI: Mary Kalafut, MD; coordinators: Krista Greiner, CCRC;

Ileanna Iedelson, RN, BSN.

38. MercyHospital, Sioux City, Iowa(probands enrolled, 3): PI: Jennifer Pary, MD; coordinator: Deb Motz.

39. Morton Plant Hospital - Neuroscience Institute, Clearwater, Florida (probands enrolled, 3): PI: Ajay Arora, MD; coordinators: Jo Simpson,Teresa Jones, Victoria Bernsee.

40. CharlesR.DrewUniversity of Medicine and Science, Los Angeles, California(probands enrolled, 1): PI:Lowell Nelson, MD; coordinators: Marcia Montenegro, RN.

41. RochesterGeneralHospital, Rochester, New York (probands enrolled, 1): PI: Joshua Hollander, MD; coordinator: Cheryl Weber.

42. OSFStrokeCenter, Peoria, Illinois(probands enrolled, 1):PI: David Wang, DO; coordinator: Mary Buttice.

43. VanderbiltUniversityMedicalCenter, Nashville, Tennessee(probands enrolled, 1): PI: Anne E. O’Duffy, MD; coordinator: Diane Brown.

44. Tri-State Neurology, Huntington, West Virginia (probands enrolled, 1): PI: Carl McComas, MD: coordinators: Jenny Edwards, RN; Christy Franklin, RN.

45. The StrokeCenter at HartfordHospital, Hartford, Conneticut:PI: Isaac Silverman, MD; coordinator: Martha Ahlquist, LPN, CCRP.

46. MassachusettsGeneralHospital, Boston, Massachusetts: PI: Karen Furie, MD; coordinator: Susan Bliss.

47.Saint Joseph Mercy Oakland, Pontiac, Michigan:PI: Lionel Glass, MD; coordinators: Connie Parliament; Janet Bolenbaugh.

48. Park Nicollet Clinic, St. Louis Park, Minnesota: PI: Sandra Hanson, MD; coordinator: Jane Archer.

49. Drexel Neurological Associates, Philadelphia, Pennsylvania: PI: Carole Thomas, MD; coordinator: Jack Medendorp, RN, BSN.

50. VirginiaMasonMedicalCenter, Seattle, Washington: PI: Michael Elliott, MD; coordinator: Allison Singer.