Supplementary Table 3. Characteristics of 21 case-control or two-arm cohort studies about ovarian cancer risk by endometriosis

Study / Period of enrollment / Study
design / Assessment of endometriosis / Age (yr) / No. of events/sample size (%) / Adjustment of potential
confounding factors
endometriosis / Non-endometriosis
Ness et al. 2000 / 1994-1998 / Case-control / Self-report / 20-69 / 66/151
(43.7) / 698/1,977
(35.3) / Age, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, hysterectomy, parity, race
Ziogas et al. 2000 / 1994-1995 / Case-control / Self-report / ≤75 / 106/191
(55.5) / 1,115/2,513 (44.4) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Royar et al. 2001 / 1993-1996 / Case-control / Self-report / ≤75 / 3/11
(27.3) / 224/743
(30.1) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Olson et al. 2002 / 1986 -1998 / Cohort / Self-report / 55-69 (38*) / 3/1,392
(0.2) / 100/36,042
(0.3) / Age
Borgfeldt et al. 2004 / 1969-1996 / Case-control / Histology / ≥10 / 81/27,050
(0.3) / 181/81,254
(0.2) / Age, adnexectomy, hysterectomy
Glud et al. 2004 / 1987-1999 / Case-control / Self-report / 35-79 / 8/24
(33.3) / 532/2,063
(25.8) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race

- Supplementary Table 3 continued

Study / Period of enrollment / Study
design / Assessment of endometriosis / Age (yr) / No. of events/sample size (%) / Adjustment of potential
confounding factors
endometriosis / Non-endometriosis
Pike et al. 2004 / 1992 - 1998 / Case-control / Self-report / 18-74 / 129/253
(50.1) / 1,194/2,908 (41.1) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Brinton et al. 2005 / 1978-1998 / Cohort / Histology / 44.2* / 50/2,491
(2) / 1,181/99,421 (1.2) / Age, adnexectomy, BMI, calendar at entry, history of tubal ligation, hysterectomy, parity
Terry et al. 2005 / 1992-2003 / Case-control / Self-report / Not limited / 69/156
(44.2) / 767/1,903
(40.3) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Risch et al. 2006 / 1998-2003 / Case-control / Self-report / 35-79 / 47/99
(47.5) / 327/826
(39.6) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Merrit et al. 2008 / 2002-2005 / Case-control / Self-report / 18-79 (57.8*) / 106/191
(55.5) / 1,115/2,513 (44.4) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Moorman et al. 2008 / 1999-2006 / Case-control / Self-report / 20-74 / 88/154
(57.1) / 738/1,711
(43.1) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race

- Supplementary Table 3 continued

Study / Period of enrollment / Study
design / Assessment of endometriosis / Age (yr) / No. of events/sample size (%) / Adjustment of potential
confounding factors
endometriosis / Non-endometriosis
Rossing et al. 2008 / 2002-2005 / Case-control / Self-report / 35-74 / 66/163
(40.5) / 524/1,723
(30.4) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Cunningham et al. 2009 / 1999-2006 / Case-control / Self-report / Not limited / 30/64
(47.6) / 252/684
(36.8) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Wu et al. 2009 / 1998-2002 / Case-control / Self-report / 18-74 / 51/88
(58) / 553/1,195
(46.3) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Lurie et al. 2010 / 1993-2008 / Case-control / Self-report / 19-88 / 44/97
(45.3) / 348/1,051
(33.1) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Aris et al. 2010 / 1997-2006 / Cohort / Histology / 41.6* / 41/2,521
(1.6) / 251/24,693
(1) / Age, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, hysterectomy, parity, race

- Supplementary Table 3 continued

Study / Period of enrollment / Study
design / Assessment of endometriosis / Age (yr) / No. of events/sample size (%) / Adjustment of potential
confounding factors
endometriosis / Non-endometriosis
Ness et al. 2011 / 2003-2008 / Case-control / Self-report / ≥25 / 55/162
(34) / 537/1,943
(27.6) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Balogun et al. 2011 / 2006-2008 / Case-control / Self-report / ≥18 (64*) / 28/46
(60.9) / 301/712
(42.3) / Age, BMI, breastfeeding, duration of oral contraceptive use, family history of ovarian cancer, history of tubal ligation, parity, race
Vitonis et al. 2011 / 1992-2008 / Case-control / Histology / 40-85 / 456/894
(51) / 642/1,567
(41) / Age
Bodmer et al. 2011 / 1995-2009 / Case-control / Histology / 61.2* / 16/88
(18.2) / 1,592/10,693 (14.9) / –

Abbreviations: BMI, body mass index. *Data presented as mean age.