Supplementary Table 2 Clinical and molecular characteristics of the 37 patients with AML included in the study.

Case / Sex / Age / FAB classification / AML type / Karyotype / PP2A hyper-phosphorylation / PP2Ac protein expression / SET OE / SETBP1 OE / CIP2A OE / JAK2-V617F / PPP2R1B DR / PPP2R5B DR / PPP2R5C DR / FLT3-ITD / NPM1 mutated
17695 / M / 56 / AML-M2 / de novo / 47,XY,+8 / no / reduced / no / no / yes / yes / yes / no / yes / no / no
19608 / F / 76 / AML-M2 / sAML / 46,XX / no / reduced / no / no / ND / yes / yes / yes / yes / no / no
24860 / F / 42 / AML-M5 / de novo / 48,XX,del(1)(p21),
+4,+6,del(11)(q21),
der(11)add(11)(p15) / no / reduced / no / no / no / no / yes / ND / ND / no / no
22271 / M / 66 / AML-M1 / sAML / 46,XY / no / reduced / no / no / no / yes / yes / yes / no / no / no
19820 / F / 46 / AML-M4 / de novo / 46,XX / no / normal / no / no / ND / no / ND / ND / ND / yes / ND
21507 / F / 53 / AML-M4 / de novo / 46,XX / no / reduced / no / no / no / no / yes / yes / yes / no / yes
25222 / F / 64 / AML-M5 / de novo / 46,XX / no / reduced / no / no / no / no / yes / yes / yes / no / yes
26164 / M / 72 / AML-M5 / de novo / 47,XY,der(3),+8 / no / normal / no / no / no / no / ND / ND / ND / no / ND
22892 / M / 68 / AML-M2 / sAML / 46,XY / yes / reduced / no / no / no / yes / yes / no / no / yes / no
15619 / M / 74 / AML-M5 / de novo / 46,XY / yes / normal / yes / no / no / no / yes / yes / yes / no / ND
19937 / M / 43 / AML-M5 / de novo / 46,XY / yes / normal / yes / no / ND / no / yes / no / yes / no / yes
24415 / M / 73 / AML-M4 / de novo / 46,XY / yes / reduced / yes / no / no / no / yes / ND / no / no / yes
Case / Sex / Age / FAB classification / AML type / Karyotype / PP2A hyper-phosphorylation / PP2Ac protein expression / SET OE / SETBP1 OE / CIP2A OE / JAK2-V617F / PPP2R1B DR / PPP2R5B DR / PPP2R5C DR / FLT3-ITD / NPM1 mutated
27578 / M / 71 / AML-M1 / de novo / 46,XY / yes / normal / yes / no / no / no / yes / yes / yes / yes / yes
18154 / M / ND / AML-M0 / de novo / 46,XY / yes / normal / no / yes / yes / no / no / no / no / no / no
19449 / M / 76 / AML-M1 / de novo / 46,XY/47,XY,+13 / yes / normal / no / yes / ND / no / no / no / ND / no / no
24212 / F / 59 / AML-M5 / de novo / 46,XX / yes / reduced / no / yes / no / no / yes / no / yes / no / no
25448 / F / 69 / AML-M7 / de novo / 46,XX,add(3)(q?) / yes / normal / no / yes / no / no / yes / yes / yes / no / no
32014 / M / 76 / AML-M6 / de novo / 46,XY,t(12;18)(p13;q22)/47,XY,idem,+19 / yes / normal / no / yes / no / ND / yes / yes / yes / ND / no
14412 / F / 61 / AML-M4 / de novo / 46,XX / yes / normal / yes / yes / ND / no / no / ND / yes / yes / yes
18425 / M / 64 / AML-M1 / de novo / 45,XY,-7,del(11)(q23),
-14,-17,-21,+3mar/
88,XXXX,cx / yes / normal / yes / yes / no / no / yes / no / no / no / no
25297 / F / 69 / AML-M7 / de novo / 46,XX/46,XX,add(3)(q?) / yes / normal / yes / yes / no / ND / no / no / no / ND / ND
27101 / M / 40 / AML-M4 / de novo / ND / yes / normal / yes / yes / yes / no / no / no / no / no / no
27298 / F / 67 / AML-M1 / de novo / 46,XX / yes / reduced / yes / yes / no / no / yes / no / no / yes / yes
27990 / M / 41 / AML-M4 / de novo / ND / yes / normal / yes / yes / no / no / no / no / no / no / no
28685 / M / 75 / AML-M0 / de novo / 46,XY,t(11;12)(q13;p13),der(12),del(17)(p13),
der(17) / yes / reduced / yes / yes / ND / no / yes / no / no / no / ND
17393 / M / 67 / AML-M5 / de novo / 46,XY / yes / reduced / no / no / no / no / no / yes / yes / no / yes
Case / Sex / Age / FAB classification / AML type / Karyotype / PP2A hyper-phosphorylation / PP2Ac protein expression / SET OE / SETBP1 OE / CIP2A OE / JAK2-V617F / PPP2R1B DR / PPP2R5B DR / PPP2R5C DR / FLT3-ITD / NPM1 mutated
17619 / F / 65 / AML-M4 / de novo / 46,XX / yes / normal / no / no / no / no / yes / yes / yes / no / yes
18937 / M / 6 / AML-M4 / de novo / 46,XY/46,XY,inv(7)(p21q36),del(11)(q13q23) / yes / reduced / no / no / ND / no / yes / yes / no / no / ND
20762 / F / 73 / AML-M4 / de novo / 46,XX / yes / normal / no / no / no / no / yes / yes / yes / yes / yes
21720 / F / 55 / AML-M0 / de novo / 46,XX / yes / normal / no / no / no / no / yes / yes / yes / no / no
23816 / F / 64 / AML-M5 / sAML / 46,XX / yes / reduced / no / no / no / no / yes / yes / yes / no / yes
24043 / M / 71 / AML-M1 / sAML / 46,XY,+8 / yes / normal / no / no / no / no / yes / yes / yes / no / no
24731 / M / 55 / AML-M1 / de novo / 46,XY / yes / normal / no / no / no / no / yes / yes / no / no / no
24756 / F / 59 / AML-M2 / de novo / 46,XX / yes / normal / no / no / no / no / yes / yes / yes / no / no
26916 / M / 64 / AML-M2 / de novo / 47,XY,+8 / yes / normal / no / no / no / no / yes / yes / yes / no / ND
27535 / M / 71 / AML-M6 / sAML / 47,XY,del(20)(q11)x2 / yes / normal / no / no / no / no / yes / yes / yes / no / ND
28827 / M / 75 / AML-M5 / de novo / 47,XY,+19 / yes / reduced / no / no / no / no / yes / no / yes / no / no