Supplementary Table 1: Parameters which were analyzed on CT in patients with Crohn’s Disease and Intestinal Tuberculosis

Radiological features / Definitions
Site of involvement
Left colon / ·  Descending colon, and/or
·  Sigmoid colon, and/or
·  Rectum
Rest of colon / ·  Caecum (without contiguous terminal ileal involvement), and/or
·  Ascending colon, and/or
·  Transverse colon
Ileocaecal region / ·  Terminal ileum (ileal area which is adjacent to the ileocaecal valve) alone, or
·  Contiguous involvement of terminal ileum and caecum
Rest of small intestine / ·  Jejunum, and/or
·  Ileum excluding the terminal ileum
Type of involvement
Length of segment
Short
Long / <3cm
3cm
Wall thickening
Symmetric
Asymmetric / Bowel wall thickening >3 mm on an adequately distended loop
Concentric thickening
Eccentric thickening
Wall enhancement / Segmental enhancement in all or part (in the case of mural stratification) of the bowel wall which is greater than that in the adjacent bowel loops
Mural stratification / Bilaminar appearance of the bowel wall with mucosal hyperenhancement and decreased intramural attenuation or a trilaminar appearance with mucosal and serosal hyperenhancement and decreased intramural enhancement.
Stricture
Short stricture
Long stricture / Lack of bowel loop distention with prestenotic dilatation
<3 cm in length
3 cm in length.
Fistula / Abnormal communication between two epithelial surfaces or from the bowel wall to the skin
Lymph Nodes
Size / Short axis measurement of either < 1cm or 1 cm
Mesenteric changes
Comb sign / Hypervascularity of the mesentery with vascular dilatation, tortuosity, and prominence of the vasa recta
Fat proliferation / Abnormal prominence of fatty tissue around the affected bowel loop
Fat stranding / Inflammation in the fat around the affected bowel loop
Peritoneal changes / Presence of peritoneal thickening and/or ascites

Supplementary Table 2: Clinical and demographic features of patients with Crohn’s disease and Intestinal Tuberculosis

Variable / CD (n=54) / ITB (n=50) / P value
Age in years ( mean + SD) / 37 ± 14.5 / 34.2 ± 13.4 / 0.3
Sex (Females) / 23 (42.6 %) / 30 (60 %) / 0.08
Duration of symptoms (months) [Median (IQR)] / 27 (16.5 – 63) / 12 (4 – 24) / < 0.001
Duration of Follow up (months) [Median (IQR)] / 14 (8 – 24) / 12 (7.8 – 14) / 0.1
Fever (n) / 16 (29.6 %) / 19 (38 %) / 0.37
Diarrhoea (n) / 37 (68.5 %) / 9 (17.6 %) / < 0.001
Constipation(n) / 6 (10 %) / 13 (26 %) / 0.05
GI bleed(n) / 17 (31.5 %) / 6 (12 %) / 0.02
Pain abdomen(n) / 42 (77.8 %) / 47 (94 %) / 0.02
Partial bowel obstruction(n) / 14 (25.9 %) / 24 (48 %) / 0.02
Weight loss(n) / 50 (92.6 %) / 45 (90 %) / 0.64
Anorexia (n) / 31 (57.4 %) / 39 (78 %) / 0.03


Supplementary Table 3: Endoscopic features of patients with Crohn’s disease and Intestinal tuberculosis

CD (n=54)
Numbers (%) / ITB (n=49)#
Numbers (%) / P value
Site of involvement
Rectum / 16 (29.6) / 4 (8.2) / 0.01
Sigmoid colon / 21 (38.9) / 5 (10.2) / 0.001
Descending colon
Not evaluated * / 19 (35.2)
2 / 4 (8.2)
0 / 0.001
Transverse colon
Not evaluated * / 15 (27.8)
5 / 7 (14.3)
1 / 0.05
Ascending colon
Not evaluated * / 15 (27.8)
10 / 13 (26.5)
2 / 0.06
Caecum
Not evaluated * / 16 (29.6)
11 / 24 (49)
5 / 0.1
Ileocaecal valve
Not evaluated * / 15 (27.8)
14 / 21 (42.8)
10 / 0.43
Terminal ileum
Not evaluated * / 22 (40.7)
17 / 11 (22.4)
20 / 0.14
Stomach / 2 (3.8) / 1 (2) / 0.27
Duodenum / 4 (7.5) / 2 (4.1) / 0.05
Jejunum / 3 (5.7) / 0 (0) / 0.13
Type of involvement
Aphthous ulcers / 8 (14.8) / 2 (4.1) / 0.07
Longitudinal ulcers / 21 (38.9) / 3 (6.1) / <0.001
Transverse ulcers / 5 (9.3) / 14 (28.6) / 0.01
Superficial ulcers / 11 (20.4) / 8 (16.3) / 0.59
Deep ulcers / 36 (66.7) / 29 (59.2) / 0.43
Cobble stoning / 7 (13) / 2 (4.1) / 0.11
Pseudopolyps / 5 (9.3) / 2 (4.1) / 0.29
Nodularity / 11 (20.4) / 13 (26.5) / 0.46
Stricture / 17 (31.5) / 20 (40.8) / 0.32

* Not evaluated: Proximal colonic segment could not be evaluated by ileo-colonoscopy because of an obstructing stricture

# Colonoscopy report was not available for 1 patient