Supplementary Table S1 List of potential cancer-derived IgG-interacting proteins identified by LC-MS/MS analysis.

Accession no. / Protein name / Official
symbol / Mascot scorea / Queries matched / In-gel
digestionb
gi|49456389 / L-lactate dehydrogenase A chain / LDHA / 239 / 9 / a
gi|48146073 / Guanine nucleotide-binding protein subunit beta-2-like 1 / GNB2L1c / 149 / 4
gi|55959425 / Galectin-8 / LGALS8 / 118 / 5
gi|4506403 / Retinoic acid-induced protein 3 / GPRC5A / 75 / 3
gi|48146045 / Voltage-dependent anion-selective channel protein 2 / VDAC2 / 74 / 2
gi|57208781 / Phosphoribosyl pyrophosphate synthetase 1 / PRPS1 / 71 / 3
gi|4506007 / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit / PPP1CC / 54 / 1
gi|179397 / Clathrin light chain A / CLTA / 47 / 1
gi|7657198 / Probable dimethyladenosine transferase / DIMT1L / 45 / 1
gi|5453710 / LIM and SH3 domain protein 1 / LASP1 / 38 / 1
gi|49456307 / Uracil-DNA glycosylase / UNG / 38 / 1
gi|147904340 / WD repeat-containing protein 82 / WDR82 / 37 / 1
gi|48146923 / ATP synthase subunit gamma, mitochondrial / ATP5C1 / 37 / 1
gi|258547124 / Solute carrier family 25 member 42 / Slc25a42 / 34 / 1
gi|47496641 / GTP-binding nuclear protein Ran / RAN / 64 / 2 / b
gi|15029604 / 60S ribosomal protein L13 / RPL13 / 61 / 3
gi|6912634 / 60S ribosomal protein L13a / RPL13A / 335 / 16 / c
gi|4506607 / 60S ribosomal protein L18 / RPL18 / 224 / 6
gi|47115241 / Peroxiredoxin-1 / PRDX1 / 136 / 7
gi|18152783 / 60S ribosomal protein L10-like / RPL10L / 130 / 6
gi|4506903 / Serine/arginine-rich splicing factor 9 / SFRS9 / 95 / 2
gi|51980485 / 60S ribosomal protein L15 / RPL15 / 78 / 5
gi|49456405 / CD59 glycoprotein / CD59 / 59 / 2
gi|46575618 / Dermcidin / DCD / 55 / 2
gi|197304710 / Uncharacterized protein C7orf50 / C7orf50 / 40 / 1
gi|49168472 / Ras-related protein Rab-5A/B/C / RAB5A/B/C / 39 / 1
gi|15680121 / Myosin light chain 6B /6 / MYL6B/6 / 39 / 1

a Significance threshold of enumerated proteins was set at p<0.05.

b a–c correspond to those in Figure. 2

c GNB2L1 also known as RACK1