Supplementary Table 1 List of 213 Probes Representing 87 MCB- Over-Expressed Genes And

Supplementary Table 1 List of 213 probes representing 87 MCB- over-expressed genes and 121DCB-over-expressed genes as determined by Statistical Analysis of Microarrays (SAM) analysis with a false-discovery rate up to 0.01.

Gene symbol / Gene Name / Ref Seq / SAM score / Average Ratio (MCB/DCB)
MCB over-expressed genes
NM_173498 / Hypothetical protein DKFZp434C0631 / NM_173498 / 2.47 / 31.0
COL9A1 / Collagen, type IX, alpha 1 / NM_001851 / 3.97 / 25.7
PCOLCE2 / Procollagen C-endopeptidase enhancer 2 / NM_013363 / 4.27 / 24.0
IL8 / Interleukin 8 / NM_000584 / 2.22 / 23.1
COL9A3 / Collagen, type IX, alpha 3 / NM_001853 / 2.27 / 17.2
TNFRSF11B / Tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) / NM_002546 / 2.23 / 10.5
ADM / Adrenomedullin / NM_001124 / 2.01 / 10.2
CDH19 / Cadherin 19, type 2 / NM_021153 / 2.44 / 10.1
FOXL2 / Forkhead box L2 / NM_023067 / 2.52 / 9.9
ANGPTL4 / Angiopoietin-like 4 / NM_016109 / 2.68 / 8.9
BCL2A1 / BCL2-related protein A1 / NM_004049 / 2.28 / 7.5
FOXC1 / Forkhead box C1 / NM_001453 / 2.86 / 7.2
A_23_P170719 / Unknown / A_23_P170719 / 2.65 / 7.2
OCA2 / Oculocutaneous albinism II (pink-eye dilution homolog, mouse) / NM_000275 / 2.21 / 7.0
S100B / S100 calcium binding protein, beta / NM_006272 / 2.82 / 7.0
G0S2 / Putative lymphocyte G0/G1 switch gene / NM_015714 / 2.03 / 6.3
TEX12 / Testis expressed sequence 12 / NM_031275 / 2.00 / 6.2
CYP26B1 / Cytochrome P450, family 26, subfamily B, polypeptide 1 / NM_019885 / 2.43 / 6.1
VIM / Vimentin / NM_003380 / 2.07 / 5.8
IMP-2 / IGF-II mRNA-binding protein 2 / NM_006548 / 3.07 / 5.8
NOHMA / Hypothetical protein DKFZp434A1315 / NM_032132 / 2.39 / 5.6
PLOD2 / Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 / NM_000935 / 2.43 / 5.6
DAZL / Deleted in azoospermia-like / NM_001351 / 1.99 / 5.2
RIS1 / Ras-induced senescence 1 / NM_015444 / 2.41 / 5.2
ADORA2B / Adenosine A2b receptor / NM_000676 / 2.45 / 5.2
THC1858795 / AP004355 NADH dehydrogenase subunit 2 {Lepisosteus spatula}, partial (5%) / THC1858795 / 1.92 / 5.1
HRH1 / Histamine receptor H1 / NM_000861 / 1.97 / 5.1
SRrp35 / Serine-arginine repressor protein (35 kDa) / NM_080743 / 2.03 / 5.0
IL6 / Interleukin 6 (interferon, beta 2) / NM_000600 / 1.94 / 4.9
PTX3 / Pentaxin-related gene, rapidly induced by IL-1 beta / NM_002852 / 2.69 / 4.8
S100A3 / S100 calcium binding protein A3 / NM_002960 / 2.26 / 4.7
HMOX1 / Heme oxygenase (decycling) 1 / NM_002133 / 1.89 / 4.7
PLOD / Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) / NM_000302 / 2.62 / 4.7
FABP5 / Fatty acid binding protein 5 (psoriasis-associated) / NM_001444 / 2.30 / 4.7
HAPLN1 / Hyaluronan and proteoglycan link protein 1 / NM_001884 / 1.92 / 4.6
EFNB1 / Ephrin-B1 / NM_004429 / 2.01 / 4.5
FOXD1 / Forkhead box D1 / NM_004472 / 2.39 / 4.5
MYC / v-myc myelocytomatosis viral oncogene homolog (avian) / NM_002467 / 2.41 / 4.5
FLJ12442 / Hypothetical protein FLJ12442 / NM_022908 / 1.99 / 4.4
FLNA / Filamin A, alpha (actin binding protein 280) / NM_001456 / 2.00 / 4.4
SOD2 / Superoxide dismutase 2, mitochondrial / NM_000636 / 2.07 / 4.4
GAL / Galanin / NM_015973 / 2.07 / 4.4
AY358408 / Clone DNA49141 LGLL338 (UNQ338) / AY358408 / 1.88 / 4.3
ENPP2 / Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) / NM_006209 / 1.92 / 4.3
PDIP / Protein disulfide isomerase, pancreatic / NM_006849 / 1.93 / 4.3
HAS2 / Hyaluronan synthase 2 / NM_005328 / 2.18 / 4.3
C20orf42 / Chromosome 20 open reading frame 42 / NM_017671 / 1.97 / 4.3
UPP1 / Uridine phosphorylase 1 / BC047030 / 2.31 / 4.3
PLA2G4A / Phospholipase A2, group IVA (cytosolic, calcium-dependent) / NM_024420 / 2.21 / 4.3
SULT1B1 / Sulfotransferase family, cytosolic, 1B, member 1 / NM_014465 / 1.88 / 4.2
GPM6B / Glycoprotein M6B / NM_005278 / 2.08 / 4.2
LEPREL1 / Myxoid liposarcoma associated protein 4 (MLAT4) / NM_018192 / 2.21 / 4.0
FLJ22329 / Hypothetical protein FLJ22329 / NM_024656 / 2.54 / 4.0
CTSZ / Cathepsin Z / NM_001336 / 2.38 / 4.0
GABRA5 / Gamma-aminobutyric acid (GABA) A receptor, alpha 5 / NM_000810 / 1.94 / 4.0
BMP2 / Bone morphogenetic protein 2 / NM_001200 / 2.30 / 4.0
IMP-3 / IGF-II mRNA-binding protein 3 / NM_006547 / 2.00 / 4.0
SRD5A1 / Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) / NM_001047 / 2.21 / 4.0
DRCTNNB1A / Down-regulated by Ctnnb1, a / NM_032581 / 2.65 / 3.9
MGC16291 / Hypothetical protein MGC16291 / NM_032770 / 2.17 / 3.8
CEBPB / CCAAT/enhancer binding protein (C/EBP), beta / NM_005194 / 2.00 / 3.8
TNFRSF12A / Tumor necrosis factor receptor superfamily, member 12A / NM_016639 / 2.06 / 3.8
CSPG4 / Chondroitin sulfate proteoglycan 4 (melanoma-associated) / NM_001897 / 2.11 / 3.8
CXX1 / CAAX box 1 / NM_003928 / 1.89 / 3.8
ARNTL2 / Cycle-like factor CLIF / AF256215 / 2.10 / 3.7
PLAGL1 / Pleiomorphic adenoma gene-like 1 / NM_002656 / 2.34 / 3.7
THC1901508 / D87957 protein involved in sexual development {Homo sapiens}, partial (72%) / THC1901508 / 2.09 / 3.5
FLJ13391 / Hypothetical protein FLJ13391 / NM_032181 / 1.91 / 3.5
ICAM1 / Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor (ICAM1), / NM_000201 / 2.03 / 3.4
NMT2 / N-myristoyltransferase 2 / NM_004808 / 1.91 / 3.3
IL1R2 / Interleukin 1 receptor, type II / NM_004633 / 1.94 / 3.3
C20orf41 / Chromosome 20 open reading frame 41 / NM_032957 / 1.91 / 3.3
COL27A1 / cDNA FLJ11895 fis, clone HEMBA1007301, weakly similar to collagen alpha 1 (III) chain / AK021957 / 2.10 / 3.2
FJX1 / Four jointed box 1 (Drosophila) / NM_014344 / 1.89 / 3.2
BCAT1 / Branched chain aminotransferase 1, cytosolic / NM_005504 / 1.96 / 3.2
EYA1 / Eyes absent homolog 1 (Drosophila) / NM_000503 / 1.93 / 3.1
PRNP / Prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) / NM_000311 / 1.90 / 3.1
CGI-141 / CGI-141 protein / NM_016072 / 1.89 / 3.1
GNAI1 / Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 / NM_002069 / 2.00 / 3.1
FLJ11196 / FLJ11196 / NM_018357 / 2.00 / 3.0
FAD158 / Hypothetical protein AD158 / NM_032270 / 2.05 / 3.0
C9orf88 / MEG3 / AF151783 / 1.90 / 2.9
ANKH / Ankylosis, progressive homolog (mouse) / NM_054027 / 2.11 / 2.9
CSDA / Cold shock domain protein A / NM_003651 / 2.02 / 2.8
MSN / Moesin / NM_002444 / 1.89 / 2.8
CALU / Calumenin / NM_001219 / 1.96 / 2.8
KIF14 / KIAA0042 / D26361 / 1.89 / 2.8
DCB over-expressed genes
BCMP11 / Breast cancer membrane protein 11 / NM_176813 / -2.56 / 0.03
TFF3 / Trefoil factor 3 / NM_003226 / -3.36 / 0.04
TFF3 / Trefoil factor 3 / NM_003226 / -3.54 / 0.04
PIP / Prolactin-induced protein / NM_002652 / -2.75 / 0.04
ABCC11 / ATP-binding cassette, sub-family C (CFTR/MRP), member 11 / NM_033151 / -2.86 / 0.05
AGR2 / Anterior gradient 2 homolog (Xenopus laevis) / NM_006408 / -3.17 / 0.05
CYP4Z1 / Cytochrome P450 4Z1 / NM_178134 / -1.73 / 0.06
FOXA1 / Forkhead box A1 / NM_004496 / -4.77 / 0.07
SCGB2A1 / Secretoglobin, family 2A, member 1 / NM_002407 / -1.94 / 0.09
FSIP1 / Hypothetical protein FLJ35989 / NM_152597 / -2.09 / 0.09
HRASLS2 / HRAS-like suppressor 2 / NM_017878 / -2.64 / 0.09
ACOX2 / Acyl-Coenzyme A oxidase 2, branched chain / NM_003500 / -2.07 / 0.09
ERBB2 / v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) / NM_004448 / -1.91 / 0.09
LOC118430 / Small breast epithelial mucin / NM_058173 / -2.26 / 0.09
TSGA2 / Testes specific A2 homolog (mouse) / NM_080860 / -3.28 / 0.09
A_23_P139166 / Unknown / A_23_P139166 / -1.78 / 0.10
THRSP / Thyroid hormone responsive (SPOT14 homolog, rat) / NM_003251 / -1.73 / 0.11
MYB / v-myb myeloblastosis viral oncogene homolog (avian) / NM_005375 / -2.66 / 0.11
DNAJC12 / DnaJ (Hsp40) homolog, subfamily C, member 12 / NM_021800 / -2.13 / 0.11
SCGB1D2 / Secretoglobin, family 1D, member 2 / NM_006551 / -2.12 / 0.11
ESR1 / Estrogen receptor 1 / NM_000125 / -1.98 / 0.11
RET / Ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) / NM_020630 / -1.86 / 0.12
NAT1 / N-acetyltransferase 1 (arylamine N-acetyltransferase) / NM_000662 / -1.94 / 0.12
LOC124220 / Similar to common salivary protein 1 / NM_145252 / -3.62 / 0.12
ABAT / 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein / NM_020686 / -1.90 / 0.14
CEACAM6 / Carcinoembryonic antigen-related cell adhesion molecule 6 / NM_002483 / -1.78 / 0.14
DNCL2B / Dynein, cytoplasmic, light polypeptide 2B / NM_130897 / -2.27 / 0.14
KIAA0882 / mRNA for KIAA0882 protein / AB020689 / -1.95 / 0.14
KIAA1324 / Homo sapiens maba1 (KIAA1324) / NM_020775 / -3.51 / 0.15
A_23_P106814 / Unknown / A_23_P106814 / -2.38 / 0.15
ZNF552 / Zinc finger protein 552 / NM_024762 / -2.36 / 0.15
NME5 / Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) / NM_003551 / -1.81 / 0.16
A_23_P129665 / Unknown / A_23_P129665 / -1.84 / 0.16
SCGB2A2 / Secretoglobin, family 2A, member 2 / NM_002411 / -2.73 / 0.16
SPDEF / SAM pointed domain containing ets transcription factor / NM_012391 / -2.94 / 0.16
AZGP1 / Alpha-2-glycoprotein 1, zinc / NM_001185 / -2.68 / 0.16
C20orf114 / Chromosome 20 open reading frame 114 / NM_033197 / -1.70 / 0.17
EPN3 / Epsin 3 / NM_017957 / -1.88 / 0.17
ZDHHC11 / Zinc finger, DHHC domain containing 11 / NM_024786 / -2.43 / 0.17
TMEM25 / Transmembrane protein 25 / NM_032780 / -3.01 / 0.17
IL20RA / Interleukin 20 receptor, alpha / NM_014432 / -1.69 / 0.17
COX6C / Cytochrome c oxidase subunit VIc / NM_004374 / -1.87 / 0.18
VAV3 / vav 3 oncogene / NM_006113 / -2.49 / 0.18
CREB3L4 / cAMP responsive element binding protein 3-like 4 / NM_130898 / -2.92 / 0.18
TPD52 / Tumor protein D52 / NM_005079 / -2.67 / 0.19
DNALI1 / Dynein, axonemal, light intermediate polypeptide 1 / NM_003462 / -2.03 / 0.19
CA12 / cDNA FLJ20151 fis, clone COL08412 / AK000158 / -1.77 / 0.19
PLEKHA6 / Phosphoinositol 3-phosphate-binding protein-3 / NM_014935 / -2.45 / 0.19
AR / Androgen receptor / NM_000044 / -2.76 / 0.20
DACH1 / Dachshund homolog 1 (Drosophila) / NM_080759 / -1.96 / 0.20
XBP1 / Homo sapiens X-box binding protein 1 (XBP1), mRNA [NM_005080] / NM_005080 / -3.26 / 0.20
MGC14839 / Homo sapiens similar to RIKEN cDNA 2310030G06 gene (MGC14839), mRNA [NM_080659] / NM_080659 / -2.64 / 0.21
EPPK1 / EPPK1 mRNA for epiplakin 1 / AB051895 / -2.13 / 0.21
LRRC17 / Leucine rich repeat containing 17 / NM_005824 / -1.86 / 0.21
MTL5 / Metallothionein-like 5, testis-specific (tesmin) / NM_004923 / -2.21 / 0.21
FBXL16 / Hypothetical protein MGC33974 / NM_153350 / -1.84 / 0.21
GPR81 / G protein-coupled receptor 81 (GPR81), mRNA [NM_032554] / NM_032554 / -1.86 / 0.21
MGC11242 / Hypothetical protein MGC11242 / NM_024320 / -2.87 / 0.21
HRASLS3 / HRAS-like suppressor 3 / NM_007069 / -2.14 / 0.22
ELF4 / E74-like factor 4 (ets domain transcription factor) / NM_001421 / -2.14 / 0.22
KRT19 / Keratin 19 / NM_002276 / -2.25 / 0.23
PIB5PA / Phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A / NM_014422 / -2.34 / 0.24
C1orf34 / Chromosome 1 open reading frame 34 / BC004399 / -2.31 / 0.24
AP1M2 / Adaptor-related protein complex 1, mu 2 subunit / NM_005498 / -2.44 / 0.24
GSTM3 / Glutathione S-transferase M3 (brain) / NM_000849 / -2.13 / 0.25
THC1858993 / G82454 biphenyl-2,3-diol 1,2-dioxygenase III-related protein VCA0463 VCA0328 VCA0341 [imported] - Vibrio cholerae (strain N16961 serogroup O1), partial (55%) / THC1858993 / -1.74 / 0.25
C20orf103 / Chromosome 20 open reading frame 103 / NM_012261 / -2.26 / 0.26
SCGB1D1 / Secretoglobin, family 1D, member 1 / NM_006552 / -2.16 / 0.26
FLJ10980 / mRNA for KIAA1370 protein / AB037791 / -1.91 / 0.26
FLJ40504 / Hypothetical protein FLJ40504 / NM_173624 / -1.95 / 0.26
EPPK1 / EPPK1 mRNA for epiplakin 1 / AB051895 / -1.78 / 0.27
TFCP2L3 / Transcription factor CP2-like 3 / NM_024915 / -2.45 / 0.27
SLC25A4 / Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 / NM_001151 / -2.43 / 0.27
MYO5C / Myosin VC / NM_018728 / -2.10 / 0.27
A_23_P122650 / Unknown / A_23_P122650 / -2.16 / 0.29
KRT18 / Keratin 18 / NM_000224 / -2.24 / 0.29
BIK / BCL2-interacting killer (apoptosis-inducing) / NM_001197 / -1.87 / 0.29
MGC17299 / Hypothetical protein MGC17299 / NM_144626 / -2.53 / 0.29
A_23_P21882 / Unknown / A_23_P21882 / -1.70 / 0.30
ARSD / Arylsulfatase D / NM_009589 / -1.76 / 0.30
TRPS1 / Trichorhinophalangeal syndrome I / NM_014112 / -1.94 / 0.30
C17orf28 / Chromosome 17 open reading frame 28 / NM_030630 / -1.74 / 0.31
GATA3 / GATA binding protein 3 / NM_002051 / -1.75 / 0.31
KARCA1 / Hypothetical protein MGC33338 / NM_152366 / -2.26 / 0.31
C19orf32 / Polyposis locus protein 1-like 1 / NM_138393 / -1.82 / 0.31
C1orf29 / Chromosome 1 open reading frame 29 / NM_006820 / -1.85 / 0.32
IGJ / Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides / NM_144646 / -1.70 / 0.32
P2RY2 / Purinergic receptor P2Y, G-protein coupled, 2 / NM_176072 / -1.85 / 0.32
F11R / Junctional adhesion molecule 1, JAM1 / BC001699 / -2.41 / 0.32
PTE2B / Peroxisomal acyl-CoA thioesterase 2B / NM_152331 / -1.78 / 0.32
SLC9A3R1 / Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 / BC053350 / -1.94 / 0.33
RTN4RL1 / cDNA DKFZp547J144 / AL834409 / -1.90 / 0.34
KENAE / Kenae / NM_176816 / -2.08 / 0.35
TOM1L1 / Target of myb1-like 1 (chicken) / NM_005486 / -1.91 / 0.35
FXYD3 / FXYD domain containing ion transport regulator 3 / NM_005971 / -2.13 / 0.36
DHCR24 / 24-dehydrocholesterol reductase / NM_014762 / -1.75 / 0.36
MGC22679 / cDNA clone MGC:22679 / BC022324 / -1.74 / 0.36
C5orf18 / Polyposis locus protein 1 (DP1) / NM_005669 / -1.85 / 0.37
SLC9A3R1 / Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 / NM_004252 / -1.72 / 0.38
ARHGAP8 / Rho GTPase activating protein 8 / NM_181334 / -1.87 / 0.39
PTGER3 / Prostaglandin E receptor 3 (subtype EP3) / NM_198720 / -1.86 / 0.39
ZFP62 / Zinc finger protein 62 homolog (mouse) / NM_152283 / -1.85 / 0.39
CST6 / Cystatin E/M / NM_001323 / -1.82 / 0.40
MMEL2 / Membrane metallo-endopeptidase-like 2 / NM_033467 / -1.76 / 0.40
ZNF435 / Zinc finger protein 435 / NM_025231 / -1.85 / 0.40
STK16 / Serine/threonine kinase 16 / BC053998 / -1.78 / 0.41
ELL3 / Elongation factor RNA polymerase II-like 3 / NM_025165 / -1.88 / 0.43
NPDC1 / Neural proliferation, differentiation and control, 1 / NM_015392 / -2.00 / 0.44
AF026246 / Homo sapiens mRNA containing human endogenous retrovirus H and human endogenous retrovirus E sequences / AF026246 / -1.81 / 0.44
ZNF339 / Zinc finger protein 339 / NM_021220 / -1.96 / 0.44
FLJ31434 / Hypothetical protein FLJ31434 / NM_152496 / -1.74 / 0.44
EFHD1 / EF hand domain containing 1 / NM_025202 / -1.72 / 0.47
MB / Myoglobin / NM_005368 / -1.83 / 0.49
C10orf116 / Adipose specific 2 / NM_006829 / -1.95 / 0.49
CRB3 / Crumbs homolog 3 (Drosophila) / NM_174882 / -1.92 / 0.51
FLJ34633 / Hypothetical protein FLJ34633 / NM_152365 / -1.83 / 0.51
SPINT2 / Serine protease inhibitor, Kunitz type, 2 / NM_021102 / -1.71 / 0.52
SERTAD4 / SERTA domain containing 4 / NM_019605 / -1.70 / 0.53
CDH1 / Cadherin 1, type 1, E-cadherin (epithelial) / NM_004360 / -1.78 / 0.55
FLJ34633 / Hypothetical protein FLJ34633 / NM_152365 / -1.70 / 0.55
CLDN7 / Claudin 7 / NM_001307 / -1.88 / 0.55
FRP-4 / Secreted frizzled-related protein 4. [ENST00000223214] / ENST00000223214 / -1.92 / 0.60
MAL2 / Mal, T-cell differentiation protein 2 / NM_052886 / -1.87 / 0.61
FRZB / Frizzled-related protein / NM_001463 / -1.99 / 0.69
FRZB / Frizzled-related protein / NM_001463 / -1.96 / 0.70
TACSTD1 / Tumor-associated calcium signal transducer 1 / NM_002354 / -2.51 / 1.14

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