Supplementary Table 1. Commercially Available Interphase Fluorescence in Situ Hybridization

Supplementary Table 1. Commercially available interphase fluorescence in situ hybridization (iFISH) probes directed against specific gene locus which were systematically applied to the study of glioma tumors.

Gene Target / Chromosome Locus / Commercial Name/Reference code / Source
TP73 / 1 (1p36.3) / LSI 1p36/LSI 1q25 and LSI 19q13/LSI 19p13 Dual Color Probe/ ref 32-231004 / Vysis
ANGPTL1 / 1 (1q25) / LSI 1p36/LSI 1q25 and LSI 19q13/LSI 19p13 Dual Color Probe/ ref 32-231004 / Vysis
EGFR / 7 (7p12) / EGFR (7p12) / Alphasatellite 7 DNA Probe,
Dual-Color, Direct-Labelled/ ref PONCO711 / QBIOgene
ELN / 7 (7q11.23) / LSI Williams Syndrome Region Dual Color Probe
(LSI ELN/LSI 7q31 dual-color probe)/ ref 32-19004 / Vysis
TES / 7 (7q31) / LSI Williams Syndrome Region Dual Color Probe
(LSI ELN/LSI 7q31 dual-color probe)/ ref 32-19004 and ref 32-131007 / Vysis
p16=CDKN2A=INK4A / 9 (9p21) / LSI 9p21 / CEP-9 Dual Color Probe/ ref 32-190078 and ref32-131009 / Vysis
ABL1 / 9 (9q34.1) / LSI bcr/abl ES (extra signal) Dual Color Probe/ ref 32-191022 / Vysis
PTEN / 10 (10q23) / LSI PTEN SpectrumOrange / CEP 10 SpectrumGreen Dual Color Probe/ ref 32-231010 and ref 32-131010 / Vysis
RB1 / 13 (13q14) / LSI 13 / RB-1 SpectrumOrange Probe/ ref 32-190001 / Vysis
TP53 / 17 (17p13.1) / LSI p53 SpectrumOrange Probe/ ref 32-190008 and ref 32-131017 / Vysis
ZNF44 / 19 (19p13) / LSI 1p36/LSI 1q25 and LSI 19q13/LSI 19p13 Dual Color Probe/ ref 32-231004 / Vysis
GLTSCR1 & GLTSR2 / 19 (19q13.3) / LSI 1p36/LSI 1q25 and LSI 19q13/LSI 19p13 Dual Color Probe/ ref 32-231004 / Vysis
BCR / 22 (22q11.23) / LSI bcr/abl ES (extra signal) Dual Color Probe/ ref 32-191022 / Vysis

&: Centromeric probes (from Vysis) for chromosomes 7, 9, 10 and 17 labeled with spectrum green, orange and aqua fluorochromes were combined to confirm clonal evolution.