Supplemental Table S1. The targeted mutations covered in OG panel.

Gene / Mutation (DNA) / AA change / Location / COSMIC ID / Transcript / Amplicon ID
AKT1 / c.49G>A / p.E17K / 14:105246551 / 33765 / NM_005163.2 / AMPL5
AKT2 / c.49G>A / p.E17K / 19:40762959 / 159009 / NM_001626.4 / AMPL2
AKT3 / c.49G>A / p.E17K / 1:243859016 / 224779 / NM_005465.4 / AMPL1
AKT3 / c.686A>G / p.N229S / 1:243776983 / N/A / NM_005465.4 / AMPL6
AKT3 / c.1393C>T / p.R465W / 1:243668598 / N/A / NM_005465.4 / AMPL15
PIK3R2 / c.1117G>A / p.G373R / 19:18273784 / 993028 / NM_005027.2 / AMPL9
MTOR / c.4448G>A / p.C1483Y / 1:11217230 / 462615 / NM_004958.3 / AMPL10
PIK3CA / c.241G>A / p.E81K / 3:178916854 / 27502 / NM_006218.2 / AMPL16
PIK3CA / c.263G>A / p.R88Q / 3:178916876 / 746 / NM_006218.2 / AMPL16
PIK3CA / c.1090G>A / p.G364R / 3:178922321 / 86042 / NM_006218.2 / AMPL4
PIK3CA / c.1093G>A / p.E365K / 3:178922324 / 86044 / NM_006218.2 / AMPL4
PIK3CA / c.1133G>A / p.C378Y / 3:178922364 / 1041479 / NM_006218.2 / AMPL4
PIK3CA / c.1359_1361del(AGAA>A) / p.E453del / 3:178928078 / N/A / NM_006218.2 / AMPL3
PIK3CA / c.2176G>A / p.E726K / 3:178938934 / 87306 / NM_006218.2 / AMPL12
PIK3CA / c.2740G>A / p.G914R / 3:178947865 / N/A / NM_006218.2 / AMPL14
PIK3CA / c.3062A>G / p.Y1021C / 3:178952007 / 12461 / NM_006218.2 / AMPL11
PIK3CA / c.3073A>G / p.T1025A / 3:178952018 / 771 / NM_006218.2 / AMPL11
PIK3CA / c.3104C>T / p.A1035V / 3:178952049 / 17445 / NM_006218.2 / AMPL11
PIK3CA / c.3129G>T / p.M1043I / 3:178952074 / 773 / NM_006218.2 / AMPL11
PIK3CA / c.3139C>T / p.H1047Y / 3:178952084 / 774 / NM_006218.2 / AMPL11
PIK3CA / c.3145G>A / p.G1049S / 3:178952090 / 777 / NM_006218.2 / AMPL11
PIK3CA / c.344G>C / p.R115P / 3:178916957 / N/A / NM_006218.2 / AMPL8
PIK3CA / c.3140A>G / p.H1047R / 3:178952085 / 775 / NM_006218.2 / AMPL11
PIK3CA / c.1258T>C / p.C420R / 3:178927980 / 757 / NM_006218.2 / AMPL17
PIK3CA / c.1624G>A / p.E542K / 3:178936082 / 760 / NM_006218.2 / AMPL13
PIK3CA / c.3140A>T / p.H1047L / 3:178952085 / 776 / NM_006218.2 / AMPL11
PIK3CA / c.1633G>A / p.E545K / 3:178936091 / 763 / NM_006218.2 / AMPL13
GNAS / c.601C>T / p.R201C / 20:57484420 / 27887 / NM_000516.4 / AMPL7
GNAS / c.602G>A / p.R201H / 20:57484421 / 27895 / NM_000516.4 / AMPL7
GNAS / c.601C>A / p.R201S / 20:57484420 / 27899 / NM_000516.4 / AMPL7

N/A: not applicable.