Supplemental Table 2. Glossary of genes.

Abbreviation Full Name Gene Product Gene/Protein Family
AGT Angiotensinogen Angiotensinogen Renin substrate
ACE Angiotensin-converting Angiotensin-converting Zink metalloproteinase
enzyme enzyme
AT1R Angiotensin II receptor Angiotensin II receptor GPCR
type 1 type 1
AT2R Angiotensin II receptor Angiotensin II receptor GPCR
type 2 type 2
BMP4 Bone morphogenic protein 4 Bone morphogenic TGF-β superfamily
protein 4
Crebbp CREB binding protein CREB binding protein Histone
acetyltransferase
Eya1 Eyes absent homolog 1 Eyes absent homolog 1 EYA family of proteins
FoxC1 Forkhead box C1 Forkhead box C1 Forkhead family of
transcription factors
Fras1 Fraser syndrome 1 Fraser syndrome 1 Extracellular matrix
protein protein
Gata3 GATA3 GATA3 Transcription factor
that contains two
GATA-type zinc fingers
GDNF Glial cell derived Glial cell derived Neurotrophic factor
neurotrophic factor neurotrophic factor Ligand for Ret
Gli3 GLI family zinc finger 3 GLI family zinc finger 3 Transcription factor
Gpc3 Glypican 3 Glypican 3 Cell surface heparan
sulfate proteoglycan
7-HCR Alpha-helix coiled-coil rod Alpha-helix coiled-coil Role in DNA repair and
homologue rod homologue cholesterol biosynthesis
HNF1β Hepatocyte nuclearfactor Hepatocyte nuclearfactor Homeobox transcription
1β 1β factor
Ift80 Intraflagellar transport 80 Intraflagellar transport 80 Essential for the
homolog homolog function of motile and
sensory cilia
JAGGED1 JAGGED1 JAGGED1 Ligand for Notch
receptor
Kal1 Kal1 Anosmin-1 Regulates migration of
nerve cell precursors
during embryogenesis
Nphp1 Nephronophthisis 1 Nephrocystin-1 Nephronophthi-
sis types 1-9
Pax2 Paired box 2 Paired box 2 Transcription factor with
conserved DNA-
binding paired box
domain
Pex1 Peroxisomal biogenesis Peroxin 1 Peroxisomal ATPases
factor 1 p57KIP2 Cyclin-dependent kinase Cyclin-dependent kinase Cell cycle inhibitor
inhibitor 1C inhibitor 1C
Pkd1, 2 Polycystic kidney disease Polycystin 1 and 2 Polycystin proteins
Renin Renin Renin Enzyme that cleaves
AGT to produce Ang I
Ret Rearranged during RET51, RET43, RET9 Receptor tyrosine
transfection kinase, GDNF receptor
Robo2 Roundabout homolog 2 Roundabout homolog 2 Immunoglobulins
Receptor for Slit2
Sall1,4 Sal-like 1 and 4 Sal-like 1 and 4 Zinc finger transcription
factors
Six1, 2, 5 Sine oculis homeobox Sine oculis homeobox Homeobox transcription
homologs 1, 2 and 5 homologs 1, 2 and 5 factors
Slit2 Slit homolog 2 Slit homolog 2 Acts as molecular
guidance cue in cellular
migration
Ligand for Robo2
Sox9 Sex determining region Sex determining region HMG-box class DNA-
Y-box 9 Y-box 9 binding proteins
Tbx3 T-box 3 T-box 3 Transcription factors
which share a common
DNA-binding domain,
the T-box
UMOD Uromodulin Uromodulin Urinary protein
UPIIIA Uroplakin 3A Uroplakin 3A Uroplakins , a group
of transmembrane
proteins expressed
on the apical surface of
the bladder epithelium
XPNPEP3 X-prolyl aminopeptidase 3 X-prolyl aminopeptidase 3 M24B subfamily of X-
prolyl peptidases

GPCR- G protein-coupled receptor, CREB- (cAMP response element-binding), HMG- High-Mobility Group, Ang- angiotensin.