Supplemental File 4:Clinic Diagnosis according to Atopic Parent and CAP Status (n=95)
Stage 2 Diagnosis / Atopic Parent + CAP(n=26) / Atopic Parent + No CAP
(n=34) / No Atopic Parent
+ CAP
(n=16) / No Atopic Parent
+ No CAP
(n=19)
DNA / 3 / 4 / 2 / 5
Normal* / 2 / 4 / 2 / 5
Normal with low FEV1 / 1 / - / - / -
Normal with low FVC / - / - / 1 / -
Normal with low FEV1 and FVC / 3 / 3 / 2 / 1
Normal with pectusexcavatum / - / 1 / - / -
Normal with pectuscarinatum / - / 1 / - / -
Scoliosis requiring surgery +
low FEV1 + low FVC / 1 / - / - / -
Scoliosis; probable Holt Oram Syndrome. Referred to Geneticists. / 1 / - / - / -
Spasmodic croup + low IgG1 / - / 1 / - / -
Asthma / 5 / 11 / 1 / 6
Did Not Attend + Dr diagnosis of Asthma† / 7 / 7 / 4 / 2
Asthma + low IgG1 / - / 1 / - / -
Asthma + low HIB‡ and low pneum§ / 1 / - / - / -
Asthma +low pneum / - / 1 / - / -
Asthma + right middle lobe scarring on HRCT + low HIB + low B +T cells / 1 / - / - / -
Asthma + bronchiectasis + obliterativebronchiolitis + low pneum + low IgM / 1 / - / - / -
Bronchiectasis + low pneum + low IgG2 / - / - / 1 / -
Bronchiectasis + obliterativebronchiolitis + low HIB / - / - / 1 / -
Chronic productive cough +
low pneum + peribronchial thickening on HRCT / 1 / - / -
Suspected chronic suppurative lung disease; Did Not Attend further investigation / - / - / 1 / -
Chronic lung disease of prematurity + low HIB / - / - / 1 / -
Chronic lung disease secondary to CAP (requiring Extra Corporeal Membrane Oxygenation) and prematurity + low pneum / 1 / - / - / -
* Normal: asymptomatic at clinic visit and normal respiratory examination
†diagnosis made by GP or other Paediatrician
‡HIB: HaemophilusInfluenzae specific antibody titre
§Pneum: Pneumococcal specific antibody titre