Supplement Table 1. Summary of question scores

Item / Description / Original Domain / Score, mean (SD)
1 / Need to blow nose / Physical / 2.11 (1.43)
2 / Sneezing / Rhinological / 1 (0-5)*
3 / Runny nose / Rhinological / 2.02 (1.40)
4 / Cough / General / 1 (0-5)*
5 / Post nasal discharge (dripping at the back of your nose) / Rhinological / 2 (0-5)*
6 / Thick nasal discharge / Rhinological / 2.19 (1.57)
7 / Ear fullness / Ear/facial / 1 (0-5)*
8 / Dizziness / Ear/facial / 1 (0-5)*
9 / Ear pain / Ear/facial / 1 (0-5)*
10 / Facial pain/pressure / General / 1 (0-5)*
11 / Difficulty falling asleep / Sleep / 2 (0-5)*
12 / Waking up at night / Sleep / 2.13 (1.50)
13 / Lack of a good night’s sleep / Sleep / 2 (0-5)*
14 / Waking up tired / Sleep / 2 (0-5)*
15 / Fatigue / General / 2 (0-5)*
16 / Reduced productivity / General / 2 (0-5)*
17 / Reduced concentration / General / 2 (0-5)*
18 / Frustrated/restless/irritable / Psychological / 2 (0-5)*
19 / Sad / Psychological / 1 (0-5)*
20 / Embarrassed / Psychological / 0 (0-5)*
21 / Sense of taste/smell / Rhinological / 2.05 (1.72)
22 / Blockage/congestion of nose / Rhinological / 2.70 (1.55)

* Median (Range)

Supplement Table 2. Comparison of different translations of SNOT-22

Language / Reference No / Author / Patients / Validity / Reliability / Patient's Mean Total Score
Chinese / 10 / Lu, W / 64 CRS patients, 20 healthy control / ? (No full text accessible) / ? (No full text accessible) / ? (No full text accessible)
Czech / 12 / Schalek, P / 52 CRS patients undergoing ESS, 50 non-sinonasal disease patients, 50 healthy student / Alpha: Preoperative 0.852, at 3 months postoperative 0.904, at 6 months postoperative 0.877 / - / 38.52
Brazilian Portuguese / 18 / Kosugi, EM / 89 CRS patients undergoing ESS, 113 healthy control / Alpha: 0.9276 / 10-14 days interval Inter-interviewer r0.81 Intra 0.72 / 62.39
Danish / 15 / Lange, B / 40 CRS patients / Alpha: 0.83, retest 0.92 / - / 29.73
Lithuanian / 20 / Vaitkus, S / 48 CRS with/without polyp patients (in which 36 undergoing surgery), 137 general subjects without sinonasal disease / Alpha: 0.89, retest 0.93 / Pearson correlation coefficient 0.72 / 44.52
Greek / 13 / Lachanas, VA / 76 CRS with/without polyp patients (in which 32 undergoing surgery), 120 healthy volunteers / Alpha: 0.84, retest 0.89 / Pearson correlation coefficient 0.91 / 50.17
French / 11 / de Dorlodot, C / 376 CRS patients, 46 healthy control / Alpha: 0.93 / Test-retest reliability coefficent 0.78 / 41.0
Spanish / 16 / de Los Santos, G / 60 CRS patients, 59 no sinonasal disease control patients / Alpha: 0.91 / Overall ICC 0.87, Average ICC 0.71 / 47.18
European Portuguese / 17 / de Vilhena, D / 50 CRS patients, 15 healthy volunteer / Alpha: 0.935 / Pearson correlation coefficient 0.99 / (Median 32.5)
Swedish / 14 / Sahlstrand-Johnson, P / 270 rhinosinusitis patients including recurrent acute rhinotinusitis and CRS / Alpha: 0.91 / - / 51.8
Persian / 19 / Jalessi, M / 30 patients with nasal septal deviation, 30 healthy control / Alpha: 0.898 / Pearson correlation coefficient 0.85 / 25.6
Turkish / 21 / Hancı, D / 52 CRS with/without Polyp patients, 104 volunteer / Alpha: 0.88, retest 0.90 / Pearson correlation coefficient 0.97 / 64.25
Thai (Current Study) / - / Numthavaj, P / 229 CRS with/without polyp patients / Alpha: 0.94 / Median ICC 0.64 / 38.15