Suppl. Table 1: patient characteristics

# / Age / Gender / Resection / Growth
pattern / TNM / Mutational
status / miR-29b
rel expr.
1 / 55 / f / Lobectomy / solid / ypT2a ypN2 L0 V0 / KRAS p.G12C / 0.36
2 / 56 / m / Lobectomy / acinar / pT1b pN2 pM1b(BRA) L1 V0 / KRAS p.G12C / 0.24
3 / 64 / f / Pneumonectomy / acinar / rypT4 ypN2 pM1a L1 V0 R1 / EGFR p.E746_A750del / 0.09
4 / 75 / f / Lobectomy / acinar / pT1a pN cM0 L1 V0 / KRAS p.G12D / 0.24
5 / 67 / m / Lobectomy / acinar / ypT1b ypN2 L0 V0 Pn0 / wt / 0.19
6 / 75 / f / Lobectomy / acinar / pT3 pN1 L1 V2 Pn0 / KRAS p.G12D / 0.26
7 / 61 / f / Lobectomy / solid / pT4 pN1 L1 V0 Pn0 / KRAS p.G12C / 0.13
8 / 58 / m / Lobectomy / papillary / pT3 pN2 L1 V1 Pn0 / wt / 0.03
9 / 72 / f / Lobectomy / solid / pT2b pN2 cM0 L1 V1 Pn1 / EGFR p.L858R / 0.79
10 / 78 / m / Lobectomy / acinar / pT3 pN2 cM0 L1 V0 Pn0 / wt / 0.03
11 / 64 / f / Lobectomy / solid / ypT2a ypN1 cM0 L1 V0 Pn1 / wt / 0.02
12 / 57 / m / Pneumonectomy / solid / pT4 pN2 cM0 V0 L0 Pn0 R1 / wt / 0.03
13 / 81 / f / Lobectomy / papillary / pT2a pN2 cM0 V1 L1 Pn0 / wt / 0.19
14 / 50 / m / Lobectomy / micropapillary / pT2a pN3 L1 V1 R1 / EGFR p.L747_S752>P753S / 0.17
15 / 76 / m / Lobectomy / acinar / pT1b N1 cM0 / wt / 0.24
16 / 66 / m / Lobectomy / acinar / pT3 pN1 cM0 / wt / 0.51
17 / 50 / f / Pneumonectomy / solid / pT2p N1 / KRAS p.G12V / 0.37
18 / 51 / m / Lobectomy / solid / pT1a pN2 cM0 / KRAS p.G12V / 0.18
19 / 60 / f / Lobectomy / acinar / pT2a pN2(mi) pM1(BRA) / wt / 0.27
20 / 54 / f / Pneumonectomy / solid / pT2b pN1 / KRAS p.G12C / 0.10
21 / 78 / m / Lobectomy / acinar / pT3 pN0 cM0 V0 L0 Pn0 / wt / 0.21
22 / 76 / m / Wedge resection / acinar / pT3 N0 M1(SKI) L1 V0 Pn0 / KRAS p.G12C / 0.19
23 / 64 / m / Pneumonectomy / acinar / pT4 pN0 L1 V1 Pn0 / KRAS p.G12C / 0.19
24 / 65 / m / Biopsies / micropapillary / TxNxM1a / wt / 0.02
25 / 75 / f / Biopsies / acinar / cT4 cN2 / wt / 0.10
26 / 68 / m / Wedge resection / solid / pT2a(m) pN0-1 L0 V1 / KRAS p.G12C / 0.08
27 / 66 / f / Wedge resction / papillary / na / EGFR p.E746_A750del / 0.46
28 / 44 / f / lobectomy / acinar / pT2 pN0 / KRAS p.G12V / 0.48
29 / 74 / m / lobectomy / solid / pT2 pN2 / KRAS p.G13D / 0.29
30 / 50 / m / lobectomy / acinar / pT2 pN2 MX / wt / 0.10
31 / 53 / f / lobectomy / acinar / pT2 pN0 pM1 / KRAS p.G12C / 0.12
32 / 51 / f / lobectomy / solid / pT2 pN2 pM1 / KRAS p.G12C / 0.30
33 / 66 / f / lobectomy / papillary / pT2 pN0 / EGFR p.E746_A751del / 0.48
34 / 62 / m / lobectomy / acinar / pT2 N1 Mx / KRAS p.G12V / 0.69
35 / 70 / m / lobectomy / acinar / pT1 pN0 / wt / 0.23
36 / 60 / f / lobectomy / papillary / pT2 pN0 / wt / 0.06
37 / 55 / f / lobectomy / solid / pT1 pN1 / KRAS p.G12C / 0.15
38 / 60 / m / pneumonectomy / solid / pT2 pN0 / wt / 0.04
39 / 64 / f / lobectomy / papillary / pT2 pN0 / KRAS p.G12S / 0.04
40 / 59 / f / lobectomy / solid / pT2 pN1 / wt / 0.10
41 / 48 / f / lobectomy / solid / pT1 pN2 pM1 / KRAS p.G12C / 0.06
42 / 44 / m / lobectomy / solid / pT1 N1 M0 / KRAS p.G12D / 0.12
43 / 52 / m / wedge resection / solid/papillary / pT2 pN0 / KRAS p.G12C / 0.03
44 / 43 / f / lobectomy / papillary / pT1 pN2 / KRAS p.G13D / 0.05
45 / 51 / m / lobectomy / acinar / pT3 pN1 pMx / wt / 0.05
46 / 70 / m / pneumonectomy / solid / pT2 pN0 / wt / 0.11
47 / 67 / f / wedge resection / acinar / pT2 N2 / wt / 0.03
48 / 67 / m / wedge resection / solid / pT1 pN1 pM1 / wt / 0.04
49 / 64 / w / lobectomy / solid / pT1 pN1 / wt / 0.02
50 / 45 / f / lobectomy / solid / pT4 pN1 pM1 / wt / 0.02
51 / 58 / m / pneumonectomy / papillary / ypT2 N1 / wt / 0.07
52 / 69 / m / wedge resection / solid / pT2 / wt / 0.08
53 / 61 / f / pneumonectomy / acinar / pT2a pN1 R0 / KRAS p.G12V / 0.08
54 / 44 / f / lobectomy / solid / pT3 N0 M1(BRA) V1 R0 / KRAS p.G12C / 0.20
55 / 77 / f / wedge resection / solid / na / KRAS p.G12V / 0.18
56 / 59 / m / lobectomy / papillary / pT1b pN1 L1 / KRAS p.G12V / 0.38
57 / 62 / f / wedge resection / acinar / na / wt / 0.09
58 / 68 / m / lobectomy / solid / pT3 pN1 L1 V1 / KRAS p.G12V / 0.12
59 / 61 / m / wedge resection / solid / pT2a pN2 / KRAS p.G12V / 0.26
60 / 73 / f / lobectomy / acinar / pT3 pN0 / KRAS p.G12D / 0.04
61 / 55 / f / lobectomy / na / pT2b N0 L1 V0 / KRAS p.G12C / 0.06
62 / 67 / f / lobectomy / solid / pT3(m) pN1 L1 V1 R0 / KRAS p.G12V / 0.06
63 / 71 / m / lobectomy / solid / pT3 pN1 M1 (BRA) L1 V2 R0 / wt / 0.05
64 / 42 / f / wedge resection / solid / pT1b pN2 L0 V1 R0 / wt / 0.12
65 / 45 / f / lobectomy / solid / pT1b pN2 L1 V0 Pn0 R0 / wt / 0.38
66 / 51 / f / lobectomy / solid / pT2b pN2 V0 L1 R0 / KRAS p.G12V / 0.27
67 / 65 / m / lobectomy / solid / pT4 pN1 M1(BRA) Pn1 V1 L0 R0 / wt / 0.08
68 / 59 / m / wedge resection / solid / pT4 pN0 M1b L0 V0 R0 / wt / 0.50
69 / 80 / f / lobectomy / solid / pT2a pN1 L1 V1 Pn1 R0 / EGFR p.E746_A750del / 0.19
70 / 77 / m / pneumonectomy / solid / pT2b N1 L1 V2 Pn1 RX / KRAS p.G12V / 0.24
71 / 43 / m / pneumonectomy / solid / pT3 pN2 pM1b (BRA) L1 V1 Pn1 R0 / wt / 0.19
72 / 64 / f / pneumonectomy / solid / pT1b pN1 L1 V0 Pn0 R0 / KRAS p.G12C / 0.07
73 / 77 / m / lobectomy / acinar / pT1a pN1 L1 V0 Pn0 M1b (BRA) R1 / wt / 0.03
28 / 44 / f / lobectomy / acinar / pT2 pN0 / KRAS p.G12V / 0.48
29 / 74 / m / lobectomy / solid / pT2 pN2 / KRAS p.G13D / 0.29
30 / 50 / m / lobectomy / acinar / pT2 pN2 MX / wt / 0.10
31 / 53 / f / lobectomy / acinar / pT2 pN0 pM1 / KRAS p.G12C / 0.12
32 / 51 / f / lobectomy / solid / pT2 pN2 pM1 / KRAS p.G12C / 0.30
33 / 66 / f / lobectomy / papillary / pT2 pN0 / EGFR p.E746_A751del / 0.48
34 / 62 / m / lobectomy / acinar / pT2 N1 Mx / KRAS p.G12V / 0.69
35 / 70 / m / lobectomy / acinar / pT1 pN0 / wt / 0.23
36 / 60 / f / lobectomy / papillary / pT2 pN0 / wt / 0.06
37 / 55 / f / lobectomy / solid / pT1 pN1 / KRAS p.G12C / 0.15
38 / 60 / m / pneumonectomy / solid / pT2 pN0 / wt / 0.04
39 / 64 / f / lobectomy / papillary / pT2 pN0 / KRAS p.G12S / 0.04
40 / 59 / f / lobectomy / solid / pT2 pN1 / wt / 0.10
41 / 48 / f / lobectomy / solid / pT1 pN2 pM1 / KRAS p.G12C / 0.06
42 / 44 / m / lobectomy / solid / pT1 N1 M0 / KRAS p.G12D / 0.12
43 / 52 / m / wedge resection / solid/papillary / pT2 pN0 / KRAS p.G12C / 0.03
44 / 43 / f / lobectomy / papillary / pT1 pN2 / KRAS p.G13D / 0.05
45 / 51 / m / lobectomy / acinar / pT3 pN1 pMx / wt / 0.05
46 / 70 / m / pneumonectomy / solid / pT2 pN0 / wt / 0.11
47 / 67 / f / wedge resection / acinar / pT2 N2 / wt / 0.03
48 / 67 / m / wedge resection / solid / pT1 pN1 pM1 / wt / 0.04
49 / 64 / w / lobectomy / solid / pT1 pN1 / wt / 0.02
50 / 45 / f / lobectomy / solid / pT4 pN1 pM1 / wt / 0.02
51 / 58 / m / pneumonectomy / papillary / ypT2 N1 / wt / 0.07
52 / 69 / m / wedge resection / solid / pT2 / wt / 0.08
53 / 61 / f / pneumonectomy / acinar / pT2a pN1 R0 / KRAS p.G12V / 0.08
54 / 44 / f / lobectomy / solid / pT3 N0 M1(BRA) V1 R0 / KRAS p.G12C / 0.20
55 / 77 / f / wedge resection / solid / na / KRAS p.G12V / 0.18
56 / 59 / m / lobectomy / papillary / pT1b pN1 L1 / KRAS p.G12V / 0.38
57 / 62 / f / wedge resection / acinar / na / wt / 0.09
58 / 68 / m / lobectomy / solid / pT3 pN1 L1 V1 / KRAS p.G12V / 0.12
59 / 61 / m / wedge resection / solid / pT2a pN2 / KRAS p.G12V / 0.26
60 / 73 / f / lobectomy / acinar / pT3 pN0 / KRAS p.G12D / 0.04
61 / 55 / f / lobectomy / na / pT2b N0 L1 V0 / KRAS p.G12C / 0.06
62 / 67 / f / lobectomy / solid / pT3(m) pN1 L1 V1 R0 / KRAS p.G12V / 0.06
63 / 71 / m / lobectomy / solid / pT3 pN1 M1 (BRA) L1 V2 R0 / wt / 0.05
64 / 42 / f / wedge resection / solid / pT1b pN2 L0 V1 R0 / wt / 0.12
65 / 45 / f / lobectomy / solid / pT1b pN2 L1 V0 Pn0 R0 / wt / 0.38
66 / 51 / f / lobectomy / solid / pT2b pN2 V0 L1 R0 / KRAS p.G12V / 0.27
67 / 65 / m / lobectomy / solid / pT4 pN1 M1(BRA) Pn1 V1 L0 R0 / wt / 0.08
68 / 59 / m / wedge resection / solid / pT4 pN0 M1b L0 V0 R0 / wt / 0.50
69 / 80 / f / lobectomy / solid / pT2a pN1 L1 V1 Pn1 R0 / EGFR p.E746_A750del / 0.19
70 / 77 / m / pneumonectomy / solid / pT2b N1 L1 V2 Pn1 RX / KRAS p.G12V / 0.24
71 / 43 / m / pneumonectomy / solid / pT3 pN2 pM1b (BRA) L1 V1 Pn1 R0 / wt / 0.19
72 / 64 / f / pneumonectomy / solid / pT1b pN1 L1 V0 Pn0 R0 / KRAS p.G12C / 0.07
73 / 77 / m / lobectomy / acinar / pT1a pN1 L1 V0 Pn0 M1b (BRA) R1 / wt / 0.03