Suppl. Table 1.Baseline characteristics of the study populations.

HIV- infected subjects
Healthy subjects (n=10) / Naïve
(n=10) / not ABC-treated (n=20) / All patients ABC-treated (n=40) / Group A
(n=20) / Group B
(n=20)
Age, years (mean ±SEM) / 44±2 / 43±2 / 43±2 # / 49±7 / 51±2 / 48±2
Males, n (%) / 6 (60) / 4 (40) / 14 (70) / 28 (70) / 12 (60) / 15 (75)
Smokers, n (%) / 2 (20) / 6 (60) / 7 (35) / 11 (27) / 5 (25) / 6 (30)
Hypertension, n (%) / 0 (0) / 1 (10) / 4 (20) / 6 (15) / 4 (20) / 2 (10)
Diabetes, n (%) / 0 (0) / 0 (0) / 0 (0) / 5 (12.5) / 2 (10) / 3 (15)
Dyslipidemia, n (%) / 1 (10) / 2 (20) / 7 (35) / 10 (25) / 5 (25) / 5 (25)
HIV disease stage*, n (%):
A
B
C / NA / 8 (80)
2 (20)
0 (0) / 11 (55)
6 (30)
3 (15) / 20 (50)
14 (35)
6 (15) / 14 (70)
6 (30)
0 (0) / 6 (30)
8 (40)
6 (30) #
Risk factors for HIV infection:
Heterosexual, n (%)
Homosexual, n (%) / NA / 4 (40)
6 (60) / 10 (50)
10 (50) / 21 (52)
19 (48) / 12 (60)
8 (40) / 9 (45)
11 (55)
CD4+ count (cells/mmc) / NA / 757±99 / 570±60.2* / 748·8±57.3 / 780·5±87.2 / 713·7±74.3
HIV RNA (copies/ml) / NA / 116±81 / 35±16 / 47±12 / 36±5 / 40±8
ABC treatment duration
(months, mean±SEM) / NA / NA / NA / 45±5 / 46±7 / 47±7
Concomitant therapy
(single or in combination)
statins
antihypertensives
none / 0
0
10 / 5 (50)
5 (50)
5 (50) / 9 (45)
9 (45)
11 (55) / 8 (20)
10 (25)
16 (40) / 4 (20)
5 (25)
9 (45) / 4 (20)
5 (25)
7 (35)

*HIV disease stages according to the Centre for Disease Control and prevention classification. #= p<0.05 vs group A; *= p<0.05 vs naive by Fisher's exact test. NA: not applicable. Chi square (p=0.66).

1