Suggested Curriculum Global Educational Toxicology Uniting Project (GETUP)

Suggested curriculum Global Educational Toxicology Uniting Project (GETUP)

Part I – Pharmaceuticals, Household and Industrial Toxins

Section /Topics

1. Assessment of the acutely poisoned patient Poison centre role and activities

Review – pharmacokinetics

Epidemiology and prevention

Pre‐hospital care

Risk assessment / prediction of toxicity

Toxidromes / analytical toxicology

2. Therapeutic principles Approach to the poisoned patient / ABC

Tox ACLS overview

Antidote overview

Techniques for toxin elimination

3. Decontamination Emesis / Gastric lavage / Cathartics

Activated charcoal

Whole bowel irrigation

4. Anti‐inflammatory and analgesic drugs (1) Paracetamol (1)

5. Anti‐inflammatory and analgesic drugs (2) Paracetamol (2)

Non‐steroidal anti‐inflammatory drugs

Opioids

6. Anti‐inflammatory and analgesic drugs (3) Salicylates

Gout drugs

7. CNS / Autonomic drugs (1) Antidepressants

Serotonergic drugs

Serotonin toxicity

8. CNS / Autonomic drugs (2) Lithium

Antipsychotics

Valproic acid

9. CNS / Autonomic drugs (3) Anticonvulsants

Sedatives / hypnotics / anxiolytics

Benzodiazepine antagonists

10. CNS / Autonomic drugs (4) Anticholinergics / Physostigmine

Antihistamines

Miscellaneous antidotes

11. Drugs of Abuse (1) Alcohols

GHB and related compounds

12. Drugs of Abuse (2) Sympathomimetics / hallucinogens

Nitrites / Methylene blue

Teaching Program

13. Drugs of Abuse (3) Drug abuse, dependence and withdrawal

Hallucinogenic fungi

14. Cardiovascular (1) Anti‐arrhythmics

Digoxin FAB fragments

15. Cardiovascular (2) Calcium channel antagonists

Beta blockers

Glucagon / insulin‐dextrose / calcium

16. Cardiovascular (3) Anticoagulants / vitamin K / protamine

Methylxanthines

17. Endocrine / Gastrointestinal /

Antimicrobial Agents

Insulin / oral antidiabetic drugs

Anti‐tuberculosis drugs / pyridoxine

18. Metals Iron / desferrioxamine / arsenic / lead /

mercury / metal fumes / chelation agents

19. Industrial (1) Cyanide and antidotes

Carbon monoxide / O2 / hyperbaric O2

20. Industrial (2) Hydrofluoric acid

Other toxic gases

21. Pesticides / herbicides Organophosphates / Carbamates

Atropine / pralidoxime

Part II– Toxinology / Plants and Fungi / Environmental

Section / Week Topics

1. Snake envenoming (1) General management of snakebite

Antivenoms

2. Snake envenoming -specific

3. Spider bites

4. Insect bites

5. Marine envenoming Stonefish / Blue‐ringed octopus / Cone shell

Stingray

6. Toxic marine envenoming Scombroid / Ciguatera / Puffer fish

7. Poisonous fungi Amanita phalloides

8. Poisonous plants Oleander