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Authors: Young Shil Jang,1,2* Young Choi,2* Esther Park,2,3 Gil-dong Hong,4 and Se-Jong King1,2

Affiliations: Full information for each author

1Department of Physiology, KKK University School of Medicine, Daegu, Korea; 2Laboratory of Cell Biology, KKK Stem Cell Research Institute, KKK University, Daegu, Korea; 3Department of Urology, PPP National University School of Medicine, Busan, Korea; 4Department of Pathology, PPP National University School of Medicine, Busan, Korea

*Kam Chan Kang and Young Choi contributed equally to this work.

Address for correspondence:

Se-Jong King, MD

Department of Pathology, PPP National University School of Medicine,

101 Sejong-ro, Jung-gu, Busan, 52040, Republic of Korea

E-mail:

Funding: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (grant number, 20132211); (NRF-1412345).

ACKNOWLEDGMENTS

The authors thank Ms. Saimdang Shin, Biomedical Research Institute, PPP National University School of Medicine, for her technical assistance for this study.

DISCLOSURE

Dr. Se-Jong King is an adviser of the AAA Pharmaceutical Co. Ltd., Seou, Korea, but he made no influence on this work in relation with the company or its products. Other authors have no potential conflicts of interest to disclose.

AUTHOR CONTRIBUTION

Conceptualization: Hong GD (for Gil Dong Hong). Data curation: Kim Y, Kim GD (for Younghee Kim and Gil-Dong Kim). Formal analysis: Kim CS (for Chul-Soo Kim); ...

ORCID

Young Shil Jang http://orcid.org/0000-0002-1111-2211

Young Choi http://orcid.org/0000-0004-3333-2001

Esther Park http://orcid.org/0000-0003-4444-3344

Gil-dong Hong http://orcid.org/0000-0003-3655-3366

Se-Jong King http://orcid.org/0000-0002-6666-2266

Ethics statement

For human study

The present study protocol was reviewed and approved by the institutional review board of PPP National University College of Medicine (Reg. No. 2015001). Informed consent was submitted by all subjects when they were enrolled.

For animal research

Institutional animal care and use committee (IACUC) approval is required (No. 2015033).

For clinical trials

This is a randomized clinical trial on the second phase, registered at the Clinical Research Information Service (CRIS, http://cris.nih.go.kr), number KCT0000999. Or other international registration is acceptable.