MTR Meeting, Marseille, France
09-11 April 2008
Wednesday April 09
1800 Official opening of the meeting by Project Officer Dr. Florent Bernard
1815–1915 Lecture by invited speaker Roland Benz (University of Würzburg, Würzburg) “Structure and function of gram-negative bacterial porins”
2030 Welcome dinner
Thursday April 10
900–1000 Introduction by Project Co-ordinator Mathias Winterhalter
Scientific part 1A, chairman Matteo Ceccarelli:
1030–1100 Andrey Bessonov (Jacobs University, Bremen) “Role of charged residues of E. coli porins studied using planar lipid bilayers’’
1100–1130 Cecilia Farre (Nanion, Munich) “Automated patch clamp platforms for lipid bilayer recordings”
1130–1200 Chloe James (Université de la Méditerranée, Marseille) “Translocation of b-lactams through Enterobacterial porins”
1200–1230 Faustino Vidal-Aroca (Basilea Pharmaceutica AG, Basel) “Translocation Studies in E. coli and P. Aeruginosa”
1230–1400 Lunch break
1400–1500 Lecture by invited speaker Jeremy H. Lakey (Institute of Cell and Molecular Biosciences, Newcastle University) “Colicin N binds to the periphery of its receptor and translocator, Outer Membrane Protein F”
1500–1530 Coffee break
Scientific part 1B, chairman Paula Gameiro:
1530–1600 Eric Hajjar (University of Cagliari, Cagliari) “Molecular simulations can help understand the permeation properties of antibiotics through porin channels; methodology and proof of concept”
1600–1630 Michael Werner (EPFL, Lausanne) “Multiple Optical Tweezers combined to microfluidics as a bioanalytical tool
1630–1700 Catalin Chimerel (Jacobs University, Bremen) “Transport at the nanoscale: Temperature dependence of ion conductance”
1700–1730 Coffee break
1730–1900 Discussion with Project Officer
1930 Dinner
Friday April 11
Scientific part 2A, chairman Jean-Marie Pagès:
0900–0930 Alexander Molitor (Université de la Méditerranée, Marseille) “RamA is involved in the control of membrane permeability in multidrugresistant (MDR) E. aerogenes isolates”
0930–1000 Kozhinjampara Mahendran (Jacobs University, Bremen) “Facilitated antibiotic translocation through E.coli and E. aerogenes porins”
1000–1030 Marcos Lovelle (University of Porto, Porto) “Non-specific interactions between β-lactam antibiotics and outer membrane proteins”
1030–1100 Amit Kumar (University of Cagliari, Cagliary) “Insights on Antibiotic Translocation through Bacterial Porin from Molecular Dynamics Simulations”
1100–1115 Coffee break
Scientific part 2B, chairman Niels Fertig:
1115–1145 Que-Tien Tran (Jacobs University, Bremen) “Identification of Proteus and Providencia porins”
1145–1215 Tivadar Mach (Jacobs University, Bremen)
1215–1245 Mohammed Kreir (Nanion, Munich) “Rapid and Efficient Screening of Membrane Protein Activity: Electrophysiological Analysis of Ion channels in Proteoliposomes”
1245–1415 Lunch break
1415–1515 Lecture by invited speaker Jean-Michel Claverie (Institute for Structural Biology and Microbiology, Marseille)
1515–1530 Coffee break
1530–1630 Ralf Schmauder (EPFL, Lausanne) “Designing a fluorescence assay for beta-lactam antibiotica”
1630–1730 Scientific part 3, chairman Mathias Winterhalter:
- Round table 1: porin and membrane
- Round table 2: mutation and activity
- Round table 3: porin, antibiotics and model
1730–1900 Coffee break
1900 End of the meeting
Poster session:
Posters will be hung on Wednesday and discussed during coffee breaks