Questionnairemainmeasures(frompregnancytotheageof24months)

Baselinequestionnaire

Demographicdata:parentalcitizenship,yearsinItaly(ifforeign),placeofbirthofgrandparents.

Socialbackground:parentaloccupations,parentaleducationallevel,employment.

HouseholdcompositionandHousing,indoorandoutdoorpollution:crowding(person/room),ownership,dimension,numberofrooms,floor,presenceofmouldormoisture,availabilityofgaswaterheater,airconditioning,typesofheatingandcookingathome,aircirculation,useofchemicalsinthehome,proximitytoheavytraffic,pets.

Leisureandlifestyle:maternalleisureandsportactivityoneyearbeforepregnancy,maternalpre-pregnancysmokingandalcoholuse,specialnutritionalneeds,useofsalt.

Health:paternalandmaternal(pre-pregnancy)weightandheight,maternaltypeofdelivery,breastfeeding,menarcheageandmenstrualcycleregularity,parentalweightatbirth,parentalmorbidities,inparticulardiabetesandallergies;parentalsleeppattern.

Reproductivehistory:previousreproductiveoutcomes,infertility,previouschildrenbreastfeeding,weightandgender,gestationalage.

Pregnancy:emotionalaspects(onpregnancyandinthelastmonthusingtheGHQ-12,gestationalweekatthefirstvisit,numberofultrasoundcheck,antenataldiagnosistests,otheraspects(contactwithpets,typeofwork,useofchemicals,sportactivity,hoursatopenair,snore,activeandpassivesmoking,alcoholuse,diet);morbiditiesanddruguse;hospitaladmission;vitaminsupplementation;pregnancyweightgain.

Delivery:earlybreastfeeding,newbornsleepposition.

Firstfollow-upquestionnaire(6monthsoflife)

For each month of life (from birth to 6 months):weightandheight, breastfeeding,weaning,hoursofsleep,pacifieruse,passivesmoking.

From birth to six months:foodsitemswiththemonthofintroduction;morbiditiesanddrugs; day nursery.

Last 24 hours:fooditemsandquantity.

Secondfollow-upquestionnaire(12monthsoflife)

Child growth:neurodevelopmentassessment,weightandheight.

Child health:diseases,hospitaladmittance,emergencyroomvisits,drugs administered,unintentionalinjuries.

Child care:daynursery,motherandfatheractivitieswithchild,numberofhoursatopenairpermonth.

Family habits:televisionviewing,maternalandpaternalsmokinghabit,childpassivesmokingexposure.

Child nutrition:breastfeeding,semi-quantitativefoodfrequency.

Child sleep:questionsfrom “briefscreeningquestionnaireforinfantsleep”.

Socioeconomic position:maternalandpaternaloccupationalchangesfrombirthtothefirstbirthday, family income.

Household composition and housing:changesovertime.

Maternal mood:mother-to-infantattachmentscale,generalhealthquestionnaire(12items),positivityscale.

Thirdfollow-upquestionnaire(24monthsoflife)

Child growth:neurodevelopmentassessment,weightandheight.

Child health:diseases,hospitaladmittance,emergencyroomvisits,drugs administered,unintentionalinjuries.

Child care:daynursery,motherandfatheractivitieswithchild.

Childactivities.

Family life style:maternalandpaternalsmokinghabit,childpassivesmokingexposure.

Child nutrition:breastfeeding,dietarypatternsandfeedingstyle.

Child sleep:questionsfrom “briefscreeningquestionnaireforinfantsleep”.

Socioeconomic position:maternalandpaternaloccupationalchangesfromthelastfollow-up.

Household composition and housing:changesovertime.