Publications by Graduates and Associates of the Graduate School GRK 880
[Graduates and associates of the GRK 880 are underlined; shared first authorships are marked by asterisks (*)]
2007
Gross S, van Ree RM, Oterdoom LH, de Vries AP, van Son WJ, de Jong PE, Navis GJ, Zuurman MW, Bierhaus A, Gans RO, Bakker SJ. Low Levels of sRAGE Are Associated With Increased Risk for Mortality in Renal Transplant Recipients. Transplantation 84:659-63 (2007)
Feng Y, vom Hagen F, Lin J, Hammes HP: Incipient diabetic retinopathy--insights from an experimental model. Ophthalmologica 221:269-74 (2007)
Feng Y, vom Hagen F, Pfister F, Djokic S, Hoffmann S, Wagner P, Lin J, Deutsch U, Hammes HP: Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression. Thromb Haemost 97:99-108 (2007)
Sauerhoefer S, Yuan G, Braun GS, Deinzer M, Neumaier M, Gretz N, Floege J, Kriz W, van der Woude F, Moeller MJ. L-carnosine, a substrate of carnosinase-1, influences glucose metabolism. Diabetes56:2425-32 (2007)
Riedl E, Koeppel H, Brinkkoetter P, Sternik P, Steinbeisser H, Sauerhoefer S, Janssen B, van der Woude F, Yard B. A CTG Polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells. Diabetes 56:2410-3 (2007)
Schneider UC, Schilling L, Schroeck H, Nebe CT, Vajkoczy P, Woitzik J. Granulocyte-macrophage colony-stimulating factor-induced vessel growth restores cerebral blood supply after bilateral carotid artery occlusion. Stroke 38:1320-8 (2007)
Liu Z, Hoeger S, Schnülle P, Feng Y, Goettmann U, Waldherr R, van der Woude FJ, Yard BA. Donor dopamine pretreatment inhibits tubulitis in renal allografts subjected to prolonged cold preservation. Transplantation 83:297-303 (2007)
Hoeger S, Goettmann U MD, Liu Z, Schnuelle P, Birck R, Braun C, van der Woude FJ, Yard BA Dopamine treatment of brain-dead rats mediates anti-inflammatory effects both by hemodynamic stabilization and D-receptor stimulation. Transpl Int 20:790-9 (2007)
Abdulahad WH, Stegeman CA, van der Geld YM, Doornbos-van der Meer B, Limburg PC, Kallenberg CG. Functional defect of circulating regulatory CD4+ T cells in patients with Wegener's granulomatosis in remission. Arthritis Rheum 56:2080-91 (2007)
Abdulahad WH, Stegeman CA, Limburg PC, Kallenberg CG.CD4-positive effector memory T cells participate in disease expression in ANCA-associated vasculitis. Ann NY Acad Sci 2007; 1107: 22–31.
Popa ER, Stegeman CA, Abdulahad WH,van der Meer B, Arends J, Manson WM, Bos NA, Kallenberg CG, Cohen Tervaert JW. Staphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis. Rheumatology 46:1029-33 (2007)
Hoeger S, Gottmann U, Liu Z, Schnuelle P, Birck R, Braun C, van der Woude FJ, Yard BA.Dopamine treatment in brain-dead rats mediates anti-inflammatory effects: the role of hemodynamic stabilization and D-receptor stimulation. Transpl Int 20:790-9 (2007)
Liu Z,Hoeger S, Schnuelle P, Feng Y, Goettmann U, Waldherr R, van der Woude FJ, Yard B. Donor dopamine pretreatment inhibits tubulitis in renal allografts subjected to prolonged cold preservation. Transplantation83:297-303 (2007)
Rafat N, Hanusch C, Brinkkoetter P, Schulte J, Zijlstra JG, Brade J, van der Woude FJ, van Ackern K, Yard BA, Beck GC. Circulating endothelial progenitor cells in septic patients: correlation with severity and mortality. Crit Care Med 35:1677-1684 (2007)
Beck GC, Rafat N, Yard B, Hanusch C. Die Rolle endothelialer Progenitorzellen in der Sepsis.
Anaesthesist 56:423-428 (2007)
HanuschC, NowakK,. Gill IS, TörlitzP, Rafat N, Mueller A, Van Ackern K, Yard B, BeckGC. Hypothermic preservation of lung allograft inhibits CINC-1, ELAM and VCAM expression, without affecting leukocyte infiltration. Clin Exp Immunol149:364-71 (2007)
Falkowska-Hansen B*, Falkowski M*, Metharom P, Krunic D, Goerdt S: Clathrin-coated vesicles form a unique net-like structure in liver sinusoidal endothelial cells by assembling along undisrupted microtubules. Exp Cell Res 313:1745-1757 (2007)
2006
Schledzewski K*, Falkowski M*, Moldenhauer G, Metharom P, Kzhyshkowska J, Ganss R, Demory A, Falkowska-Hansen B, Kurzen H, Ugurel S, Geginat G, Arnold B, Goerdt S: Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis. J Pathol 209:67-77 (2006)
Brinkkötter PT, Beck GC, Göttmann U, Loesel R, Schnetzke U, Rudic B, Hanusch C, Rafat N,Liu Z, Weiss C, Leuvenink HG, Ploeg R, Braun C, Schnülle P, van der Woude FJ, Yard BA. Hypothermia-induced loss of endothelial barrier function is restored after dopamine pretreatment: role of p42/p44 activation. Transplantation 82:534-42 (2006)
Abdulahad WH,van der Geld YM, Stegeman CA, Kallenberg CG.Persistent expansion of CD4+ effector memory T cells in Wegener's granulomatosis. Kidney Int 70:938-47 (2006)
Woitzik J, Schneider UC, Thome C, Schroeck H, Schilling L. Comparison of different intravascular thread occlusion models for experimental stroke in rats. J Neurosci Methods151:224-31 (2006)
J. Tuettenberg, C. Friedel, P. Vajkoczy. Angiogenesis in malignant glioma – a target for antitumor therapy? Crit Rev Oncol Hematol 59181-93 (2006)
Lin J, Bierhaus A, Bugert P, Dietrich N, Feng Y, vom Hagen F, Nawroth P, Brownlee M, Hammes HP: Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy. Diabetologia 49:1089-96 (2006)
Pannicke T, Iandiev I, Wurm A, Uckermann O, vom Hagen F, Reichenbach A, Wiedemann P, Hammes HP, Bringmann A: Diabetes alters the osmotic swelling and membrane characteristics of glial cells in the rat retina. Diabetes 55:633-9 (2006)
Martens JH, Kzhyshkowska J, Falkowski-Hansen M, Schledzewski K, Gratchev A, Mansmann U, Schmuttermaier C, Dippel E, Koenen W, Riedel F, Sankala M, Tryggvason K, Kobzik L, Moldenhauer G, Arnold B, Goerdt S: Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis. J Pathol 208:574-589 (2006)
Woitzik J, Hecht N, Schneider UC, Pena-Tapia PG, Vajkoczy P. Increased vessel diameter of leptomeningeal anastomoses after hypoxic preconditioning. Brain Res 1115:209-12 (2006)
Woitzik J, Pena-Tapia PG, Schneider UC, Vajkoczy P, Thome C. Cortical perfusion measurement by indocyanine-green videoangiography in patients undergoing hemicraniectomy for malignant stroke. Stroke 37:1549-51 (2006)
Rafat N*, Beck GC*, Brinkkoetter P, Hanusch C, Schulte J, Haak M, van Ackern K, van der Woude FJ, Yard BA. Heterogeneity in lipopolysaccharide responsiveness of endothelial cells identified by gene expression profiling: role of transcription factors. Clin Exp Immunol 143,523-33 (2006)
Gottmann U, Brinkkoetter PT, Bechtler M, Hoeger S, Karle C, Schaub M, Schnuelle P, Yard B, van der Woude FJ, Braun C. Effect of pre-treatment with catecholamines on cold preservation and ischemia/reperfusion-injury in rats. Kidney Int 70:321-8 (2006)
Kzhyshkowska J, Mamidi S, Gratchev A, Kremmer E, Schmuttermaier C, Krusell L, Haus G, Utikal J, Schledzewski K, Scholtze J, Goerdt S. Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is upregulated in alternatively activated macrophages and is associated with chronic inflammation of the respiratory tract. Blood 107:3221-8 (2006)
Kzhyshkowska J, Workman G, Cardo-Vila M, Arap W, Pasqualini R, Gratchev A, Krusell L, Goerdt S, Sage EH. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. J Immunol176:5825-32 (2006)
2005
Beck G, Hanusch C, Brinkkoetter P, Rafat N, Schulte J, van Ackern K, Yard B: Effects of dopamine on cellular and humoral immune responses in septic patients. Anaesthesist 54:1012-20 (2005)
vom Hagen F, Feng Y, Hillenbrand A, Hoffmann S, Shani M, Deutsch U, Hammes HP: Early loss of arteriolar smooth muscle cells: more than just a pericyte loss in diabetic retinopathy. Exp Clin Endocrinol Diabetes 113:573-6 (2005)
Hoffmann J, Feng Y, vom Hagen F, Hillenbrand A, Lin J, Erber R, Vajkoczy P, Gourzoulidou E, Waldmann H, Giannis A, Wolburg H, Shani M, Jaeger V, Weich HA, Preissner KT, Hoffmann S, Deutsch U, Hammes HP: Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries, determine vessel plasticity. FASEB J 19:2035-6 (2005)
Hansen B, Longati P, Elvevold K, Nedredal GI, Schledzewski K, Olsen R, Falkowski M, Kzhyshkowska J, Carlsson F, Johansson S, Smedsrod B, Goerdt S, McCourt P: Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding. Exp Cell Res 303:160-173 (2005)
Janssen B, Hohenadel D, Brinkkoetter P, Peters V, Rind N, Fischer C, Rychlik I, Cerna M, Romzova M, de Heer E, Baelde H, Bakker SJ, Zirie M, Rondeau E, Mathieson P, Saleem MA, Meyer J, Koppel H, Sauerhoefer S, Bartram CR, Nawroth P, Hammes HP, Yard BA, Zschocke J, van der Woude FJ. Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. Diabetes 54:2320-7 (2005)
Jesnowski R, Furst D, Ringel J, Chen Y, Schrodel A, Kleeff J, Kolb A, Schareck WD, Lohr M. Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine. Lab Invest 85:1276-91 (2005)
Kzhyshkowska J, Gratchev A, Brundiers H, Mamidi S,Krusell L, Goerdt S. Phosphatidylinositide 3-kinase activity is required for stabilin-1-mediated endosomal transport of acLDL. Immunobiol 210:161-173 (2005)
Tuettenberg J, Grobholz R, Korn T, Wenz F, Erber R, Vajkoczy P. Continuous low dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme. J Cancer Res Clin Oncol 131:31-40 (2005)
Hammes HP, Lin J, Wagner P, Feng Y, vom Hagen F, Krzizok T, Renner O, Breier G, Brownlee M, Deutsch U. Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy. Diabetes 53:1104-10 (2005)
2004
Kzhyshkowska J, Gratchev A, Martens J, Pervushina O, Mamidi S, Johansson S, Schledzewski K, Hansen B, He X, Tang J, Nakayama K, Goerdt S. Stabilin-1 localises to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors. J Leukoc Biol 76:1151-61 (2004)