CURRICULUM VITAE
Majid Shahbazi PhD
Medical Cellular & Molecular Research Center
Talghani Children University hospital
Bolv. Janbazan, Zip cod- 4916668197
Gorgan, Iran
Positions:
Since 2004 I have been working in Gorgan University of Medical Sciences as an assistant professor & Director of Medical Cellular & Molecular Research Center.
2001-2003 Post-doctoral position on the Wellcome trust for cell matrix center on gene expression of Cycline-Dependent Kinase Inhibitors (CDKIs) on chondrocytes in Dr Gillian Wallis and Dr Ray Boot-Handford labs, which is funded by National Institute of Health (NIH) Arthrit Research Council (ARC)
Training:
1998-2001: PhD in the field of immunology and genetics, under supervision of professor Ian V Hutchinson
The Subject was: GROWTH FACTOR GENES Polymorphisms. (EGF, IGF-I, PDGF, bFGFand VEGF) in control and diseases.
1997-1998: MSc in Immunology & immmunogetics.
1987-1990: MSc in medical parasitology from school of Public Health University of medical sciences the subject was study of cross reactivity between hydatic cyst and Actinomycetes.
1983-1987: BSc from school of Public Health University of medical sciences.
Publication
1. Majid Shahbazi, Reza Abdolmohammadi, Hamid Ebadib, Touraj Farazmandfar. Novezl functional polymorphism in IGF-1 gene associated with multiple sclerosis: A new insight to MS. Multiple Sclerosis and Related Disorders. 13 (2017) 33–37
2. Reza Abdolmohammadi, Saleh Shahbazi Azar, Ayyoob Khosravi, Majid Shahbazi. CCR5 polymorphism as a protective factor for hepatocellular carcinoma in hepatitis B virus-infected Iranian patients. Asian Pac J Cancer Prev. Accepted 2016
3. Ehsan Alaee, Behnaz Bazrafshan, seyed Ali Reza Azaminejad, Mahnaz Fooladi Nejad, Majid Shahbazi. The association between prolonged jaundice and UGT1A1 gene polymorphism (G71R) in Gilbert’s syndrome. Journal of Clinical and Diagnostic Research (JCDR). Accepted 2016
4. Fatemeh T Shamsabadi, Mohammad Reza Akbari Eidgahi, Parvaneh, Mehrbod, Nasibeh Daneshvar, Zeenathul Nazariah Allaudin, Ahad Yamchi, Majid Shahbaz. Survivin, a Promising Gene for Targeted Cancer Treatment. Asian Pac J Cancer Prev. 17 (8), 3709-3717
5. Nadia Ghasemian, Majid Shahbazi. Interferon Gamma Gene Polymorphism (+874 T > A) and Chronic Hepatitis B in the Population of Gorgan, North-Eastern Iran. doi: 10.5812/jjm.33639. Jundishapur Journal of Microbiology. 2016 August; 9(8):e33639
6. Saleh Shahbazi Azar, Maryam Mansoori, Marzieh Attar, Majid Shahbazi. Tumor Necrosis Factor Alpha -308 G/A Single Nucleotide Polymorphism and Susceptibility to Hepatocellular Carcinoma via Hepatitis B Infection. Asian pacific journal of cancer prevention. Asian Pac J Cancer Prev, 17 (7), 3381-3384
7. Majid Shahbazi, Javad Sadeghi allah abadi, Danial Roshandel, Maryam Koochaki, Hosein Amiri, Rahim Kohansal, Seied Mohammad Baghbanian, Mahdi Zamani. Combination of IL-10 gene promoter polymorphisms with HLA-DRB1*15 allele are associated with multiple sclerosis. The Indian Journal of Medical Research.accepted 14/Jul/16
8. Marzieh Attar, Saleh Shahbazi Azar, Majid Shahbazi. Interlukin-6 -174 promoter polymorphism intensifies susceptibility to hepatitis B virus as a risk factor for hepatocellular carcinoma in an Iranian population. Asian Pac J Cancer Prev, 17 (5), 2395-2399
9. زینب پورهاشم، مهدی عباسیان، مجید شهبازی، احد یامچی. بیان هترولوگ هورمون کلسی تونین در باکتری E.coli . مجله علمی دانشگاه علوم پزشکی گرگان. پذیرش: 24/12/94
10. فرناز گلشن، مجید شهبازی، کامران حیدری. اثر تنظیمی فاکتور تحریک کننده کلنی گرانولوسیت بر تعداد تخمک گزاری و موفقیت لانه گزینی رویان های حاصل از آمیزش در موش سوری نژاد NMRI. مجله علمی دانشگاه علوم پزشکی گرگان. پذیرش:27/4/95
11. Maryam Mansoori, Masoud Golalipour, Shahriar Alizadeh, Ataollah Jahangirerad, Seyed Reza Khandozi, Habibollah Fakharai and Majid Shahbazi. Genetic variation in the ABCB1 gene may lead to mRNA level change: Application to gastric cancer cases. Asian pacific journal of cancer prevention. 2015;16(18):8467-71.
12. محمد حسین آقاجانی، عباس تهذیبی، مجید شهبازی. کلونینگ و بیان پروتئین پاراتیروئید به صورت محلول در باکتری اشرشیاکلی. مجله علمی دانشگاه علوم پزشکی گرگان، زمستان 94، دوره 17، شماره 4
13. Ayyoob Khosravi, Bita Javan, Mohammad Amin Tabatabaiefar, Hamid Ebadi, Davood Fathi, Majid Shahbazi. Association of Interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population. Journal of Neuroimmunology. 2015 Nov 15;288:114-9
14. Masoumeh Ghasemi, Elham Kashani, Azadeh Fayyaz, Marzieh Attar, Majid Shahbazi. Interleukin-1 alpha variation is associated with the risk of developing preeclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology . 193 (2015) 75–78
15. Hamidreza Iranpoor, Eskandar Omidinia, Venus Vatankhah, Vahid Gharanjik ,Majid Shahbazi. Expression of Recombinant Human Insulin-like Growth Factor Type 1 (rhIGF-1) in Escherichia coli. Avicenna Journal of Medical Biotechnology. Vol. 7, No. 3, July-September 2015
16. Touraj Farazmandfar, Mohammad Reza Haghshenas, Majid Shahbazi. Inhibition of HIV-1 by a Lentiviral Vector with a Novel Tat-Inducible AU2c Expression System and a Specific Tropism to the Target Cells. Human gene therapy, volume 26 number 00. doi: 10.1089/hum.2015.031
17. Mahakizadeh Simin; Jahanshahi Mehrdad; Haidari Kamran, Shahbazi Majid. Dopamine Receptors Gene Expression in Male Rat Hippocampus after Administration of MDMA (Ecstasy). Int. J. Morphol. 33(1):301-308, 2015.
18. Arash Tahmasebifar, Yaghoub Yazdani, Pooria Gill, Majid Shahbazi. Nanoscopic Study of Gold Nanorods Used for Efficient Delivery of Sirna in Cancer NanoTherapy. American Journal of Advanced Drug Delivery. 2014
19. Alireza Haghighi, Davood Fathi, Majid Shahbazi, Mohammad-Mahdy Motahari, Bethany Friedman. Identification of a c.601 C>G mutation in the CCM1 gene in a kindred with multiple skin, spinal and cerebral cavernous malformations. Journal of the Neurological Sciences (2013)
20. Kollaee A, Ghaffarpor M, Pourmahmoudian H, Shahbazi M, Zamani M: Investigation of CD24 and Its Expression in Iranian Relapsing-Remitting Multiple Sclerosis. Int J Neurosci. 2011 Dec;121(12):684-90
21. M.Zamani, M.Mehri, A.Kollaee, P.Yenki, M.Ghaffarpor,M.H.Harirchian M.Shahbazi: Pharmacogenetic Study on the Effect of Rivastigmine on PS2 and APOE Genes in Iranian Alzheimer. Dement Geriatr Cogn Disord Extra 2011; 1:180–189.
22. Shahbazi M, Roshandel D, Omidineya E, Rashidbaghan A: Interaction of HLA-DRB1*1501 allele and TNF-alpha -308 G/A single nucleotide polymorphism in the susceptibility to multiple sclerosis. Clin Immunol. 2011; 139(3):277-81.
23. Shahbazi M, Ebadi H, Fathi D, Roshandel D, Mohamadhosseni M, Tahmasebi A, Shahbazi S, Zamani M, Rashidbaghan A. HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian population. Mult Scler. 2010; 16(10):1173-7.
24. Shahbazi M, Roshandel D, Ebadi H, Fathi D, Zamani M, Boghaee M, Mohammadhoseeeni M, Rshaidbaghan A, Bakhshandeh A, Shahbazi S.High frequency of the IL-2 -330 T/HLA-DRB1*1501 haplotype in patients with multiple sclerosis. Clin Immunol. 2010 ;137(1):134-8
25. Shahbazi M, Ebadi H, Fathi D, Roshandel D, Mahamadhoseeni M, Rashidbaghan A, Mahammadi N, Mahammadi MR, Zamani M. CCR5-delta 32 allele is associated with the risk of developing multiple sclerosis in the Iranian population. Cell Mol Neurobiol. 2009; 29(8):1205-9.
26. Shahbazi M, Pravica V, Nasreen N, Fakhoury H, Fryer AA, Strange RC, Hutchinson PE, Osborne JE, Lear JT, Smith AG, Hutchinson IV.Association between functional polymorphism in EGF gene and malignant melanoma. Lancet. 2002; 359(9304): 397-401.
27. Shahbazi M, Fryer AA, Pravica V, Brogan IJ, Ramsay HM, Hutchinson IV, Harden PN.Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection. J Am Soc Nephrol. 2002; 13(1): 260-4.
Presentation
1. Marzieh Attar, Maryam Mansoori, Majid Shahbazi. Evaluation of IL6 gene polymorphism (position: -174) in Gastric cancers patients and healthy controls. The Second International Gastrointestinal Cancer Congress. 14 - 16 October 2015, Olympic Hotel, Tehran, Iran
2. Azam Bakhshandeh, Majid Shahbazi. Reviewing effect of paraoxonase gene on coronary artery disease.2nd international and 14th Iranian Genetic Congress. 21-23 may 2016, Shahid Beheshti University, Tehran, Iran
3. Ehsan Alaee, Behnaz Bazrafshan, seyed Ali Reza Azaminejad, Mahnaz Fooladi Nejad, Majid Shahbazi. Evaluation of polymorphism UDGT1 (G71R) in the neonates with prlonged icter. Third National Congress on Cellular and Molecular News in Non-Contagious Diseases. 13-15 May 2015, Babol University of Medical Science. Babol. Iran
4. Parham Nejati, Reza Salehi Manzari, Mahdi Raeatnavaz, Majid Shahbazi. Evaluation of TNF-alpha gene promoter polymorphism (position -308) in patients with Coronary Artery Disease and healthy people. First international and 13th Iranian Genetic Congress.May 24-26, 2014. Tehran, Iran
5. Masoomeh Mohammad Zadeh, Majid Shahbazi,Kamran Haidari. The Effects of estradiol and ECG combination on ZP3 Gene in mouse oocyte.Word Congress of Reproductive Biology. Sep 2-4, 2014. Scotland
6. Alireza Azizi, Majid Shahbazi, Kamran Haidari. The Effects of Mesenchymal Stem Cell-Conditioned Medium on the fertilization rate, embryo development and OCT-4 gene expression og 8-cell NMRI mice embryos.Word Congress of Reproductive Biology. Sep 2-4, 2014. Scotland
7. Samaneh Naeimipour, Marzieh Attar,Azam Bakhshandeh,Majid Shahbazi. Investigation of frequency of interleukin-13 polymorphism (position +110) in multiple sclerosis patients and control group. 10th International Iranian Ms congress. 2013, Isfahan, Iran
8. Azam Bakhshandeh, Marzieh attar, Samaneh naeimipour, Behnaz Bazrafshan, Parastoo kush, Majid shahbazi. Evaluation of HLA-DQ gene polymorphism (DQ-A1 position: 0102) inMS patients andhealthy population. 10th International Iranian Ms congress. 2013, Isfahan, Iran
9. Behnaz Bazrafshan, Parastoo Kusha, Azam Bakhshandeh, Marzieh Attar, Samaneh Naeimipour, Majid shahbazi. Evaluation of HLA-DQ gene polymorphism (DQ-B1 position: 0602) inMS patients andhealthy population. 10th International Iranian Ms congress. 2013, Isfahan, Iran
10. Samaneh Naeimipour, Reza Salehi Manzari, Aref Salehi, Seied Ali Sharifian, Marzieh Attar1, Majid shahbazi. Investigation of InterLukin-13 ( +110( polymorphism in patients with Coronary Artery Disease and healthy people. 2nd international Preventive Cardiology congress. 16-18 oct 2013. Shiraz, Iran
11. Behnaz Bazrafshan, Reza Salehi Manzari, Samaneh Naeimi Pour, Seied Ali Sharifian, Aref Salehi, Majid Shahbazi. Study of Functional Insulin-Like Growth Factor 1 gene polymorphism in position -383 in people with Coronary Artery Disease (CAD) and healthy control. 2nd international Preventive Cardiology congress. 16-18 oct 2013. Shiraz, Iran
12. Marzieh Attar, Reza Salehi Manzari, Seied Ali Sharifian, , Samaneh Naeimipour, Majid shahbazi. Evaluation of mthfr gene polymorphism (position C677T) in people with Coronary Artery Disease and healthy controls. 2nd international Preventive Cardiology congress. 16-18 oct 2013. Shiraz, Iran
13. Marzieh Attar, Majid Shahbazi. Association of IL6-174 promoter polymorphism with hepatitis B infection in an Iranian population. 3nd Iranian genetic in medicine Congress. 15-16 may 2013. Tehran, Iran.
14. S.ziyaie, Z.siyamarzgoie, M.baghbaniyan, M.shahbazi. Evaluation of genotyping in GM-CSF (position - 1916) in multiple sclerosis patients & healthy controls Iranian population. 3nd Iranian genetic in medicine Congress. 15-16 may 2013. Tehran, Iran
15. Reza Salehi Manzari, Aref Salehi, Hossein Ali Sharifian, Samaneh Naeimipour, Marzieh Attar, Majid Shahbazi . Study of Functional Vascular Endothelial Growth Factor gene polymorphism in position -2578 in people with CoronaryArtery Disease (CAD) and healthy control. 3nd Iranian genetic in medicine Congress. 15-16 may 2013. Tehran, Iran
16. Shahbazi M., Koochaki M., Sadeqi J., Fathi D. The susceptibility of multiple sclerosis is influenced by IL-10 promoter polymorphisms and their combination with HLA-DRB1*15 alleles, among Iranian population. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
17. Ziaee S., Siamarzgoie Z., Baghbanian M., Shahbazi M. Evaluation of genotyping in GM-CSF in positions of GM-CSF (-1916) in multiple sclerosis patients & healthy controls Iranian population. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
18. Safari R , Sadeqi J, Koochaki M , Ebadi H ,Shahbazi M. Genetic variation of Nerve Growth Factor )NGF( gene in MS patients and healthy Turkmen and non-Turkmen samples. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
19. Saleh Shahbazi, Davood Fathi, Majid Shahbazi. High frequency of the IL-2 −330 T/HLA-DRB1*1501 haplotype in patients with multiple sclerosis. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
20. Shahbazi M, Roshandel D , omidnyiab E , Rshaidbaghan A ,bakhshandeh A, Attar M. Interaction of HLA-DRB1*1501 allele and TNF-alpha−308 G/A single nucleotide polymorphism in the susceptibility to multiple sclerosis. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
21. Khosravi Ayyoob, Bita Javan, Mehrnaz Izadpanah, Majid Shahbazi. Association of IL-1β gene polymorphisms with multiple sclerosis in Iranian population. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
22. Abdolmohammadi R, Ebadi H, Bakhshande A, Shahbazi M. Novel functional IGF-1 promoter polymorphism (-383C>T) Association with the susceptibility to multiple sclerosis. The 9th international MS congress of Iran. Tehran, Iran, 1-2 Nov 2012
23. Ghasemi M. Shahbazi M. Evaluation of IL-1alpha gene polymorphism (position -889) in pre-eclampsia and healthy pregnancy. 12th Iranian Genetic congress, 21-23 May 2012. shahid beheshti university, Tehran, Iran (Persian)
24. Ghasemian N. Shahbazi M. Frequency determination of IFN_gamma gene polymorphisms in HBs-Ag positive individuals and healthy controls. 12th Iranian Genetic congress, 21-23 May 2012. shahid beheshti university, Tehran, Iran (Persian)
25. Javan B., Shahbazi M. polymorphisms of interleukin-1 Beta Genes in Patients with Chronic Hepatitis B in Iran. 4th international Tehran Hepatitis Congress. Nov. 2011
26. Abdolmohammadi R. et al. Association of IGF-1 promoter polymorphism (-383C>T) with the susceptibility to multiple sclerosis.2nd Genetic in Medicine congress, Tehran, Iran, 20-21 June 2011
27. Mansoori M. et al. Association of TNF-α promoter polymorphism (-308G>A) with the outcome of hepatitis B virus infection. 2nd Genetic in Medicine congress, Tehran, Iran, 20-21 June 2011
28. Bita Javan, et al. Polymorphism of interleukin-1 receptor antagonist gene in patients with Chronic hepatitis B in Iran. 2nd Genetic in Medicine congress, Tehran, Iran, 20-21 June 2011
29. Tahmasebifar A. et al. HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian population. 2nd Genetic in Medicine congress, Tehran, Iran, 20-21 June 2011
30. Shahbaziazar S., et al. High frequency of the IL-2 −330 T/HLA-DRB1*1501 haplotype in patients with multiple sclerosis. 2nd Genetic in Medicine congress, Tehran, Iran, 20-21 June 2011
31. Bita Javan, Mohammad Reza Kalani, Ayyoob Khosravi, Maryam Mansoori, Reza Abdolmohammadi, Majid shahbazi: Polymorphisms association of interleukin-1 alpha genes in patients with chronic hepatitis B. The first international student congress on cell and molecular medicine. Shiraz, Iran(17-19 february 2011)
32. Abdolmohammadi Reza, Ayyoob khosravi, Maryam Mansoori, Bita Javan, Saleh Shahbazi, Majid Shahbazi. Association between CCR5 polymorphisms and susceptibility to HBV infection. The first international student congress on cell and molecular medicine. Shiraz, Iran(17-19 february 2011)
33. Javad Sadeghi allah abadi, Majid Shahbazi. Il-10 promotor polymorphism and their combination with HLA-DRB allels are associated with multiple sclerosis in Iranian population. 12th student’s international conferences on biomedical interdisciplinary research. Sep 2011. Isfahan. Iran