PSY 485 – Lecture 4A: Absorption

Practice Quiz #4A

1. / The_____ controls ingoing and outgoing substances from entering the brain:
A) spinal cord
B) cerebellum
C) Blood Brain Barrier
D) nucleus
2. / Which of theses choices makes for poor absorption in the body.
a. Lipid soluble
b. smaller particles
c. polarized molecules
d. un-ionized
3. / Which of the following is NOT a function of the blood-brain barrier?
a. It acts as a barrier to poisons
b. It retains neurotransmitters
c. It regulates nutrient supplies
d. all of the above
4. / Which of the following is a function of the Blood-Brain Barrier?
a. Acts as a barrier to poisons
b. Regulates nutrient supplies
c. Maintains a stable brain environment
d. All of the above
5. / All of the following factors are important for a drug to best be absorbed except ____?
a. lipid soluble
b. small in size
c. nonpolar
d. ionized
6. / Which of the following are not correct statements about the Blood Brain Barrier (BBB)?
a. maintains stable environment
b. barrier to poisons
c. is complete at birth
d. regulates nutrient supplies
7. / Which of the following is NOT a function of the Blood Brain Barrier?
a. to maintain a stable brain environment
b. to serve as a barrier to poisons
c. to regulate nutrient supplies
d. to create chemicals for the brain to use
8. / Which of the following do not cause weakening of the BBB?
A. Trauma
B. Infection
C. Aging
D. Weight
9. / Which one of these options is not true? The blood brain barrier______.
a) is incomplete at birth
b) retains neurotransmitters and other chemicals
c) has cells that are loosely packed
d) regulates nutrient supplies
10. / The brain comprises ___ percent of the body's entire mass, but receives about ____ percent of the blood flow from the heart.
A. 1, 10
B. 2, 20
C. 3, 30
D. 4, 40
11. / What is the function of the blood- brain barrier?
a) maintains stable brain environment.
b) is a barrier to poison.
c) it retains nutrients and other chemicals
d) all of the above
12. / Which of the following characteristics does not allow for best absorption?
a. lipid soluble
b. small
c. nonpolar
d. ionized
13. / At what age is the Blood Brain Barrier “done” developing?
A. Never
B. 2 Years Old
C. 5 Years Old
D. At Birth
14. / If a lipid-soluble drug is ionized, it causes its solubility ______.
a. increase.
b. decrease.
c. increase or decrease depending on the drug.
d. unchanged.
15. / What kind of molecule is water???
a. polar, hyrophobic, ionizes (decreases solubility)
b. nonpolar, hydrophilic, little ionization (increases solubility)
c. polar, hydrophilic, ionizes (decreases solubility)
d. nonpolar, hydrophobic, little ionization (increases solubility)
16. / Which of the below actions is not a function of the blood-brain barrier?
a. regulates nutrients such as glucose
b. keeps out certain poisons
c. retains neurotransmitters and other chemicals
d. keeps the brain insulated
17. / At what age is the BBB complete, or most of the way complete?
a. at birth
b. one year old
c. two years old
d. three years old
18. / What is the main function of the Blood Brain Barrier (BBB)?
a. To maintain a stable brain environment
b. To create a barrier to poisons and to retain Neurotransmitters and other chemicals needed to function
c. To regulate nutrient supplies for the brain
d. All of the above
19. / Which of the following molecules do NOT have the best absorption?
A. lipid soluble
B. small
C. polar
D. un-ionized
20. / When discussing the best way drugs are absorbed in our body they named four different characteristics that go into account, choose one?
A) ionized
B) non-lipid soluble
C) Small
D) Polar
21. / A drug crosses the lipid bilayer of a cell most easily when it is:
a. negatively charged
b. positively charged
c. polar
d. nonpolar
22. / Which of the following in a true statement about the Area Postrema?
a. It is a safety mechanism.
b. The blood brain barrier is weaker at this point.
c. Substances can enter the brain at the Area Postrema.
d. All of the above
23. / which of the following does not apply to the best absorption of a drug?
a. water-soluble
b. small molecule
c. nonpolar
d. un-ionized
24. / Is blood acidic or alkaline and what is its PH?
a acidic, 1.2
b acidic, 9.1
c alkaline, 2.5
d alkaline, 7.4
25. / What are teratogens?
A) Chemicals that inhibit neurons.
B) Chemicals that enhance the effect of a drug.
C) Chemicals that are only active in the brain.
D) Chemicals that cause birth defects.

Practice Quiz 4A: Answer Key

Q # / Ans / Reference
1. / C / Power Point 9/11
2. / C / Lecture 4, p: 4
3. / D / Lecture 4A, p.5
4. / D / Lecture 4, slide 13
5. / D / lecture 4a, slide 29
6. / C / lecture notes 4A, page 2
7. / D / Lecture, 4, p. 2
8. / D / lecture 4A, p.3
9. / C / lecture 4a, pg. 2-3
10. / B / Grilly, Chapter 3, pg. 43
11. / D / lecture 4A, page 3
12. / D / Lecture 4, p. 4
13. / B / Lecture notes
14. / B / Lecture 4-A "Solubility: Ionization"
15. / C / Lecture 4A, Page 6
16. / D / lecture #4A, (notes)
17. / D / lecture 4A page 3
18. / D / Lecture 4a p.14
19. / C / lecture 4a p5
20. / C / Lecture 4a (Sept.11)
21. / D / lecture notes p. 3
22. / D / Lecture 4a slide 10
23. / A / lecture 4 p. 5
24. / D / lecture 4b, p. 4
25. / D / Lecture 4A, pg. 3