Proton Pump Inhibitors: an Update of Their Clinical Use and Pharmacokinetics

European Journal

of Clinical Pharmacology

Volume 64 • Number 10 • October 2008

REVIEW ARTICLES

Proton pump inhibitors: an update of their clinical use and pharmacokinetics

S. Shi ■ U. Klotz 935

Evidence for a pharmacogenetic adapted dose of oral anticoagulant in routine medical practice

L. Betquemont 953

CLINICAL TRIAL

Effect of nebicapone on the pharmacokinetics and, pharmacodynamics of warfarin in healthy subjects

L. Almeida ■ A. Falcao ■ M. Vaz-da-Si!va ■ T. Nunes ■ A.-T. Santos ■ J.-F. Rocha ■ C. Neta ■ T. Macedo ■ C. Fontes-Ribeiro ■ P. Soares-da-Silva 961

PHARMACOGENETICS

Relationship between CYP2C8 genotypes and diclofenac 5-hydroxylation in healthy Spanish volunteers

P. Dorado ■ I. Cavaco ■ M.C. Caceres ■ R. Piedade ■ V. Ribeiro ■ A. LLerena 967

Relationships between specific serum IgE, IgG, IFN-7 level and IFN-y, IFNR1 polymorphisms in patients with penicillin allergy

N. Gao ■ H.-L Qiao ■ L.-J. Jia ■ X. Tian ■ Y.-W. Zhang 971

Semi-quantitative CYP2D6 gene doses in relation to metabolic ratios of psychotropics

J.WJ- Hinrichs ■ H.M. Loovers - B. Scholten - J. van der Weide 979

PHARMACOKINETICS AND DISPOSITION

Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria

SJ. Lee • R. McGready ■ C. Fernandez ■ K. Stepniewska ■ M.K. Paw ■ SJ. Viladpai-nguen ■ K.L Thwai ■ L. Villegas ■ P. Singhasivanon ■ B.M. Greenwood ■ N J. White ■ F. Nosten 987

Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration

L.T. DiemThuy ■ L Ngoc Hung ■ P.T. Danh ■ K. Na-Bangchang 993

PHARMACOEPIDEMIOLOGY AND PRESCRIPTION

Women encounter ADRs more often than do men

Y. Zopf ■ C. Rabe ■ A. Neubert ■ K.G. GaBmann ■ W. Rascher ■ E.G. Hahn ■ K. Brune ■ H. Dormann 999

Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections

R. Fernandez Urrusuno ■ M. Pedregal Gonzalez • Ma.A. Torrecilla Rojas 1005

Antiepileptic drug utilization in children from 1997-2005— a study from the Netherlands

N.W. van de Vrie-Hoekstra ■ T.W. de Vries ■ P.B. van den Berg ■ O.F. Brouwer ■ L.T.W. de Jong-van den Berg 1013

Discontinuation of ropinirole and pramipexole in patients with Parkinson's disease: clinical practice versus clinical trials

M.E.L Arbouw ■ K.L.L. Movig ■ H.-J. Guchelaar ■ PJ.E. Poels ■ J.RR van Vugt ■ C Neef ■ ICG. Egberts 1021

SHORT COMMUNICATION

Effect of food on systemic exposure to niflumic acid following postprandial administration of talniflumate

W. Kang ■ K. Kim ■ E.-Y. Kim ■ K.-i. Kwon ■ J.S. Bang ■ Y.-R. Yoon 1027

LETTERS TO THE EDITORS

Hypercalcemia due to an interaction of all-trans retinoic acid (ATRA) and itraconazole therapy for acute promyelocytic leukemia successfully treated with zoledronic acid

R. Cordoba ■ E. Ramirez ■ S.H. Lei ■ A. Lopez de !a Guia ■ MJ. Sanjurjo ■ AJ. Carcas ■ F. Hernandez-Navarro 1031

No role for the CYP3A5*3 polymorphism in intestinal and hepatic metabolism of midazolam

D. Tomalik-Scharte ■ 0. Doroshyenko ■ J. Kirchheiner ■ A. Jetter ■ A. Lazar ■ T. Klaassen ■ D. Frank ■ C. Wyen ■ G. Fatkenheuer ■ U.Fuhr 1033

Further articles can be found at www.springerlink.com Indexed in/abstracted by Current Contents and Index Medicus.

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