Program, FASEB Summer Conference, “Glucose transport: Gateway for Metabolic Systems Biology”

July 26-31, 2015, Big Sky, Montana

Chair: Christopher Newgard, PhD, Professor, Duke University Medical Center ()

Co-chair: Ann Louise Olson, PhD, Professor, University of Oklahoma Health Sciences Center,

PROGRAM

Key: C, confirmed; W, woman; CS, confirmed speaker; New, newly invited (not on the 2013 program);

SUNDAY, July 26

Title of Session: Welcome and Evening Plenary Lecture

Session Chair & Affiliation: Christopher B. Newgard, PhD (C)

Keynote Speaker: Silvia Corvera, MD (W) (CS)

Affiliation: Univ. of Massachusetts Medical School

Tentative title of talk: “How glucose transporters move in living cells”

MONDAY, July 27, Morning

Title of Session: “Structure and Cell Biology of GLUT glucose transporters”

Session Chair & Affiliation: Susanne Keller, University of Virginia (C) (W)

Speaker 1: Anthony Carruthers PhD (CS)

Affiliation: University of Massachusetts Medical School

Tentative Title of Talk: “Sequence determinants of transport functions in GLUT glucose transporters”

Speaker 2: Konstantin Kandror, PhD (CS)(New)

Affiliation: Boston University

Tentative Title of Talk: “The insulin-responsive GLUT4 compartment”

Speaker 3: Timothy McGraw, PhD (CS)

Affiliation: Cornell-Weill Medical College

Tentative Title of Talk: “Regulation of glucose transporter exocytosis and endocytosis”

Speaker 4: Debbie Thurmond, PhD (W) (New) (CS)

Affiliation: University of Indiana Medical Center

Tentative Title of Talk: “Metabolic regulation of exocytic SNARE complexes related to glucose transport”

"Meet the Professor" lunch tables for students. Each table will be hosted by speakers from the morning session and the previous evening session.

MONDAY, July 27, Afternoon

Title of Session: Metabolic fuel selection strategies

Session Chair & Affiliation: Michael Mueckler, Washington University, St Louis (C)

Speaker 1: Debbie Muoio, PhD (W) (New) (CS)

Affiliation: Duke University Medical Center

Tentative Title of Talk: “Adaptation of muscle metabolism to overnutrition”

Speaker 2: Marcia Haigis, PhD (W) (New) (CS)

Affiliation: Harvard

Tentative Title of Talk: “Regulation of mitochondrial fuel oxidation”

Speaker 3: Rebecca Hauseler, PhD (New)(W) (CS)

Affiliation: Columbia University

Tentative Title of Talk: “Regulation of metabolic flux in the fasting/refeeding transition”

Speaker 4: Matthew Hirschey, PhD (New) (CS)

Affiliation: Duke University Medical Center

Tentative Title of Talk: “Regulation of metabolic fuel selection by protein acylation”

Number of short talks selected from abstracts: 4

TUESDAY, July 28, Morning

Title of Session: Glucose transport and adipocyte biology

Session Chair & Affiliation: Cynthia Mastick, PhD, Univ. of Nevada School of Medicine (W) (C)

Speaker 1: Michael Czech, MD (CS)

Affiliation: University of Massachusetts Medical School

Tentative Title of Talk: “Adipocyte inflammation and insulin action”

Speaker 2: Alan Saltiel, PhD (CS)

Affiliation: University of Michigan

Tentative Title of Talk: “Small GTP-protein signaling in adipocyte metabolic regulation”

Speaker 3: Cristina Rondinone, PhD (W) (New) (CS)

Affiliation: MedImmune Corporation

Tentative Title of Talk: “PTB-1B signaling in adipocytes”

Speaker 4: Paul Pilch, PhD (CS)

Affiliation: Boston University

Tentative Title of Talk: “Localizing nutrient transporters to adipocyte membranes”

TUESDAY, July 28, Afternoon

Title of Session: Nutrient sensing and metabolism

Session Chair & Affiliation: Kelly Moley, Washington Univ. School of Medicine (W) (C)

Speaker 1: Morris Birnbaum, MD (CS)

Affiliation: University of Pennsylvania

Tentative Title of Talk: “Regulation of glycemic control by the liver”

Speaker 2: Bernard Thorens, PhD (CS)

Affiliation: University of Lausanne, Switzerland

Tentative Title of Talk: “Role of glucose transporters in nutrient sensing in CNS, islets, and liver”

Speaker 3: Amira Klip, PhD (W) (CS)

Affiliation: University of Toronto

Tentative Title of Talk: “Impact of diet-induced obesity on glucose transporter function”

Speaker 4: Johan Auwerx, PhD (New) Conflict—had to decline invitation, inviting Pere Puigserver (Harvard) as replacement

Affiliation: Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland

Tentative Title of Talk: “Transcriptional control of metabolic pathways”

Number of short talks selected from abstracts: 4

WEDNESDAY, July 29, Morning

Title of Session: “Metabolic Fuel Selection in the Heart and Cardiovascular Diseases”

Session Chair & Affiliation: Juleen Zierath, Karolinska Institute, Sweden (W) (C)

Speaker 1: Eric Olson, PhD (New) (CS)

Affiliation: University of Texas Southwestern Medical Center, Dallas

Tentative Title of Talk: “Regulation of heart metabolism by adipocyte miRNAs”

Speaker 2: E. Dale Abel, MD (M) (New)(CS)

Affiliation: University of Iowa

Tentative Title of Talk: “Cardiac metabolism and insulin resistance in heart failure”

Speaker 3: Daniel Kelly, MD (New) (CS)

Affiliation: Sanford-Burnham Institute, Orlando

Tentative Title of Talk: “PGC-1 signaling and metabolism in the heart”

Speaker 4: Domenico Accili, MD (New) (CS) Probable

Affiliation: Columbia University

Tentative Title of Talk: “Cross-talk between insulin signaling and lipoprotein metabolism”

"Meet the Professor" lunch tables for students. Each table will be hosted by speakers from the morning session and the previous evening session.

Wednesday, July 29, Afternoon

Title of Session: Muscle performance and physiology

Session Chair & Affiliation: Ann Louise Olson, PhD, University of Oklahoma (W) (C)

Speaker 1: Holly Van Remmen, PhD (W) (New) (CS)

Affiliation: Oklahoma Medical Research Foundation

Tentative Title of Talk: “Role of reactive oxygen species in muscle function”

Speaker 2: Ronald Evans, PhD (New) No response, still trying

Affiliation: Salk Institute

Tentative Title of Talk: “Regulation of muscle performance and metabolism by nuclear receptors”

Speaker 3: Laurie Goodyear, PhD (W) (CS)

Affiliation: Harvard

Tentative Title of Talk: “Regulation of nutrient uptake in working muscle”

Speaker 4: Jeffrey Pessin, PhD (CS)

Affiliation: Albert Einstein College of Medicine

Tentative Title of Talk: “Regulation of autophagy in muscle”

Number of short talks selected from abstracts: 4

THURSDAY, July 30, Morning

Title of Session: Mechanisms and markers of insulin resistance

Session Chair & Affiliation: Joseph Broznick, PhD, Eli Lilly (C)

Speaker 1: Scott Summers, PhD (CS)

Affiliation: Duke-NUS Medical School, Singapore

Tentative Title of Talk: “Role of ceramides in insulin resistance and glucose intolerance”

Speaker 2: David James, PhD (CS)

Affiliation: Garvan Institute, Sydney, Australia

Tentative Title of Talk: “Altered insulin signaling and impaired glucose uptake”

Speaker 3: Juleen Zierath, PhD (W) (CS)

Affiliation: Karolinska Institute, Sweden

Tentative Title of Talk: “Epigenetic markers of insulin resistance”

Speaker 4: Karen Ryan, PhD (W) (New) (CS)

Affiliation: University of Cincinnati College of Medicine

Tentative Title of Talk: “Neuroendocrine regulation of metabolism”

THURSDAY, July 30, Afternoon

Title of Session: New Horizons in Glucose Transporter Biology

Session Chair & Affiliation: Samuel Cushman, PhD (C)

Speaker 1: Barbara Kahn, MD (W) (CS)

Affiliation: Harvard

Tentative Title of Talk: “The impact of GLUT4 on systemic glucose homeostasis”

Speaker 2: Eric Berglund, PhD (New) (CS)

Affiliation: UT Southwestern

Tentative Title of Talk: “Serotonin C receptors regulate energy and glucose homeostasis ”

Speaker 3: Jonathan Bogan, PhD (CS)

Affiliation: Yale University

Tentative Title of Talk: “New insights into GLUT4 trafficking mechanisms”

Speaker 4: Jeffrey Rathmell, PhD Conflict, declined invitation, inviting Katie Wellen (Penn) as replacement

Affiliation: Duke University Medical Center

Tentative Title of Talk: “Role of glucose transport in T-cell differentiation”

Number of short talks selected from abstracts: 4