George M. Church CV
Positions, training & advisory roles (see:
1976 National Science Foundation Program Project Grant Review Committee
1974 BA Zoology & Chemistry, Duke University, Durham, NC
1984 PhD Biochem. & Mol. Biol. Harvard University, Cambridge, MA
1984 Scientist, Biogen Research Corporation, Cambridge, MA
1985-1986 Research Fellow, Anatomy, Univ. Calif., San Francisco, CA
1986/92/98-present Asst/Assoc/FullProfessor of Genetics, Harvard Medical School, Boston, MA
1997-present Director of the Lipper Center for Computational Genetics, Boston, MA
2002-present Director of the Harvard/MIT DOE Genomes-to-Life Center
2004-2015 Director of NHGRI Center for Excellence in Genomic Science (CEGS)
2006-present Broad Inst. of Harvard & MIT (1990 Genome Center co-founder)
2008-present Harvard Wyss Inst. for Biologically Inspired Engineering (founding faculty)
2005-present Founder & Director PersonalGenomes.org
1988,1992,1994 Department of Energy Genome Project Grant Review Committee
1990 NIH Genome Study Section Grant Review
1990 Co-founder of MIT, Stanford, & GTC Genome Sequencing Centers
1994-1997 National Center for Human Genome Research Review Committee
2001-present NIH BISTI, Pioneer, grant review committees, NHLBI BEE, NAS committees
Editorial Boards Nature/EMBO-MSB, Genome Biology, Omics, BioMedNet
Editorial Reviewer Nature (&NG, NB), Science, PNAS, Genome Research, NAR
Scientific Boards: Genomatica, 23andme, CGI, Life, Danaher, IBM, CDI, Enzymatics
Founder & SAB: LS9, Gen9, Knome, Joule, GSGenetics, Pathogenica, AbVitro, Essentient.
2009-present Board of Directors: Sigma-Aldrich
Honors & awards (shared award recipients in parentheses)
1974-1975 National Science Foundation Predoctoral Fellow
1985-1986 Life Sciences Research Foundation Fellow
1986-1997 Howard Hughes Medical Institute
2008 World Economic Forum Technology Pioneer Award (LS9)
2009 American Society for Microbiology Biotechnology Research Award
2010 US Presidential Green Chemistry Award (LS9)
2010 Triennial International Steven Hoogendijk Award
2011Personalized Medicine World Conference Lifetime Achievement Award
2011 Franklin Institute Bower Prize for Achievement in Science
2011 US National Academy of Sciences
Publications (see also lab members inbold)
337. Church GM, Elowitz M, Smolke CD, Voigt CA, Weiss R (2014) Realizing the potential of synthetic biology. Nature Reviews of Molec. Cell Bio.
336. Stern JNH, Yaari G, Vander Heiden JA, Church G, Donahue W, Rogier Q. Hintzen RQ, Huttner AJ, Jon D. Laman, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH , Hafler DA, Connor KC (2014) Antibody repertoire sequencing demonstrates that B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes. (submitted)
335. Ball MP, Bobe JR, Chou MF, Clegg T, Estep PW, Lunshof JE, Vandewege W, Zaranek AW, Church GM (2014) Harvard Personal Genome Project: Lessons from Participatory Public Research. Genome Medicine.
334. Davis R, Bibillo A, Fuller C, Dorwart M, Chen R, Kumar S, Kalachikov S, Russo J, Porel M, Chien M, Morozova I, Tao C, Li Z, Guo W, Korenblum D, Trans A, Aguirre A, Liu E, Harada T, Pollard J, Hu J, Cech C, Yang A, Spilman C, Thai E, Rode T, Walgren M, Lai M, De Cuir C, Hovis J, Bhat A, Stranges PB, Kasianowicz J, Church GM, Ju J (2014) Sequencing on a Genia Nanopore Chip: Proof of Principle. Advances in Genome Biology and Technology (AGBT).
333. Cybulski TR, Glaser JI, Marblestone AH, Zamft BM, Boyden ES, Church GM, Kording KP (2014) Spatial information in large-scale neural recordings. ArXiv.
332. Montague TG, Cruz JM, Gagnon JA, Church GM, Valen E (2014) CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing. Submitted.
331. Chatterjee A, Lajoie MJ, Han Xiao H, Church GM, Schultz PG (2014) Submitted.
330. Tolonen AC, Cerisy T, El-Sayyed H, Boutard M, Salanoubat M, Church GM (2014) Fungal lysis by a bacterium fermenting cellulose. Submitted.
329a.Yaari G, Vander Heiden JA, Uduman M, Gadala-Maria D, Gupta N, Stern JN, O'Connor KC, Hafler DA, Laserson U, Vigneault F, Kleinstein SH (2013) Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data. Front Immunol. 4:358. PMID: 24298272
329. Lunshof JE, Church GM, Prainsack B (2013) Raw Personal Data: Providing Access and Agency. Science 343(6169):373-4. PMID: 24458627
328. Esvelt KM, Smidler AL. Catteruccia F, Church GM (2014) in preparation.
327. Robasky K, Lewis NE, Church GM (2013) The role of replicates for error mitigation in next-generation sequencing. Nature Rev Gen. PMID: 24322726
326. Uduman M, Shlomchik MJ, Vigneault F, Church GM, Kleinstein SH (2013) Integrating B Cell Lineage Information into Statistical Tests for Detecting Selection in Ig Sequences. J. Immunology 192(3):867-74. PMID: 24376267
325. Brocker MJ, Ho JML, Church GM, Soll D, O'Donoghue P (2013) Recoding the Genetic Code with Selenocysteine. Angewandte Chemie 53(1):319-23. PMID: 24511637
324. Marblestone AH, Daugharthy E, Kalhor R, Peikon I, Kebschull J, Shipman S, Mishchenko Y, Dalrymple DA, Zamft BM, Kording KP, Boyden ES, Zador AM, Church GM (2013) Conneconomics: The Economics of Large-Scale Neural Connectomics. bioRxiv (16-Dec-2013)
323. Sok D*, Laserson U*, Laserson J*, Liu Y*, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St. John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P (2013) The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies. PLoS Pathogens. PDB: 4NPY PMID: 24385895 PMCID: PMC3875691
322. Church GM (2013) BRAIN: innovative neurotechnologies for imaging and therapeutics Dialogues Clin Neurosci. 15(3):241-3. PMID: 24174897
321. Church GM (2013) Improving Genome Understanding Nature 502:143. PMID: 24108012
320. O'Shea J, Chou MF, Quader S, Ryan J, Church GM, Schwartz D (2013) pLogo: a probabilistic approach to visualizing sequence motifs. Nature Methods. doi: 10.1038/nmeth.2646. PMID: 24097270
319. Church GM, Marblestone A, Kalhor R (2013) Rosetta Brain. In press.
318. Wang G, Yang L, Li K, Ma Q, Vaz F, Church GM, Pu WT (2013) in prep.
317. Eroshenko N, Church GM (2013) Mutants of Cre recombinase with improved accuracy. Nature Communications 4:2509. PMID: 24056590
316. Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM Rational Optimization of tolC as a Powerful Dual Selectable Marker for Genome Engineering. Nucleic Acids Research. PMID: 24452804
315. Ling J, Daoud R, Lajoie MJ, Church GM, Dieter Soll D, Lang BF (2013) Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria. Nucleic Acids Research. PMID: 24049072
314. Tzur YB, Friedland AE, Nadarajan S, Church GM, Calarco JA, Colaicovo MP (2013) Heritable Custom Genomic Modifications in Caenorhabditis elegans via a CRISPR-Cas9 System. Genetics. PMID: 23979579
313. Church G.Please reanimate. (2013) Sci Am. 309(3):12. PMID: 24003542.
312. Li JB, Church GM (2013) Deciphering the functions and regulation of brain-enriched A-to-I RNA editing. Nat Neurosci. 16(11):1518-22. PMID: 24165678
311. Marblestone AH, Zamft BM, Maguire YG, Shapiro MG, Cybulski T, Glaser JI, Amodei D, Stranges B, Kalhor R, Dalrymple DA, Seo D, Alon E, Maharbiz MM, Carmena JM,Rabaey JM, Boyden E, Church GM, Kording KP (2013) Physical Principles for Scalable Neural Recording. Frontiers in Neuroscience. (Hypothesis & Theory section).
310. Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zangi L, Judith Geva J, Roberts AE, Ma Q, Ding J, Wang DZ, Wanders RJA, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT (2013) Modeling a mitochondrial cardiomyopathy and its correction using iPSC and heart-on-chip technologies. submitted.
309. Lo C, Liu R, Lee J, Robasky K, Susan Byrne S, Lucchesi C, Aach J, Church G, Bafna V, Zhang K (2013) On the design of clone-based haplotyping Genome Biology 14(9):R100. PMID: 24028704
308. Lee J, Daugharthy E, Scheiman J, Kalhor R, Terry R, Yang JL, Li C, Amamoto R, Peters D, Ferrente TC, Marblestone A, Bernard A, Turczyk BM, Conway N, Inverso S, Levner D, Mali P, Rios X, Jeanty SSF, Jones AR, Aach J, Church GM (2014) Highly multiplexed three-dimensional subcellular transcriptome sequencing in situ. Science in press.
307. DiCarlo JE, Conley A, Penttil M, Jantti J, Wang HH, Church GM (2013) Yeast Oligo-mediated Genome Engineering (YOGE). ACS Synthetic Biology. PMID: 24160921
306. Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J (2013) Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat Biotechnol. 31(8):688-91. PMID: 23929339
305. Goodman DB, Church GM, Kosuri S (2013) Causes and effects of N-terminal codon bias in bacterial genes. Science. PMID: 24072823
304. Eminaga S, Christodoulou DC, Vigneault F, Church GM, Seidman JG. (2013) Quantification of microRNA Expression with Next-Generation Sequencing. Curr Protoc Mol Biol. Chapter 4:Unit4.17. doi: 10.1002/0471142727.mb0417s103. PMID: 23821442
303. Mali P, Esvelt KM, Church GM (2013) Cas9 as a Versatile Tool for Engineering Biology. Nature Methods 10:957-963.
302. Busskamp V, Lewis NE, Guye P, Ng AHM, Shipman S, Byrne SS, Sanjana NE, Li Y, Weiss R, Church GM (2013) Discovery of a deterministic gene regulatory network driving rapid neuronal differentiation in human stem cells. Submitted.
301. Marblestone AH, Zamft BM, Maguire YG, Shapiro MG, Cybulski T, Glaser JI, Stranges B, Kalhor R, Dalrymple DA, Boyden E, Church GM, Kording KP (2013) Physical Principles for Scalable Neural Recording. ArXiv. 24-Jun-2013.
300. Esvelt KM, Mali P, Braff J, Moosburner M, Yaung S, Church GM (2013) Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nature Methods.
299a. Lunshof JE, Ball MP (2013) Our genomes today: time to be clear. Genome Medicine 5:52. PMID: 23806003
299. Glaser J, Zamft B, Marblestone A, Moffitt, Boyden E, Church GM, Kording K. (2013) Statistical analysis of molecular signal recording. PLoS Computational Biology. PMID: 23874187
298. Konermann S, Brigham MD, Trevino A, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang FM (2013) Optical Control of Mammalian Endogenous Transcription. Nature. PMID: 23877069
297. Friedland AE, Tzur YB, Esvelt KM, Colaiacovo MP, Church GM, Calarco JA (2013) Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nat Methods. 10(8):741-3. PMID: 23817069
296. Yaung SJ, Church GM, Wang HH (2013) Recent Progress in Engineering Human-associated Microbiomes. Submitted to Methods in Molecular Biology.
295. Aach J, Mali P, Norville J, Church GM (2013) Improved evaluation of Cas9 targets in the human and other genomes. Submitted.
294. Petit E, Coppi MV, Hayes J, Tolonen A, Warnick T, Latouf W, Amisano D, Biddle A, Mukherjee S, Ivanova N, Lykidis A, Land M, Hauser L, Kyrpides N, Henrissat B, Lau J, Schnell D, Church G, Leschine S, Blanchard J (2013) Genome and transcriptome of Clostridium phytofermentans, catalyst for the direct conversion of plant feedstocks to fuels. Submitted
293. Umbarger MA, Kennedy CJ, Saunders P, Breton B, Niru Chennagiri M.S., John Emhoff, Valerie Greger , Stephanie Hallam , David Maganzini, Cynthia Micale , Marcia M. Nizzari M.S., Charles F. Towne CF, Church GM, Porreca GJ (2013) Next-Generation Carrier Screening. Genetics in Medicine. PMID: 23765052
292. Yang L, Mali P, Kim-Kiselak C, Church G (2013) CRISPR-Cas mediated targeted genome editing in human cells. Methods in Molecular Biology.
291. Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM (2013) CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotech. PMID: 23907171Supplementary info
290. Alivisatos AP, Andrews A, Boyden E, Chun M, Church G, Deisseroth K, Donoghue J, Fraser S, Lippincott-Schwartz J, Looger L, Masmanidis S, McEuen P, Nurmikko A, Park H, Peterka D, Reid C, Roukes M, Scherer A, Schnitzer M, Sejnowski T, Shepard K, Tsao D, Turrigiano G, Weiss P, Xu C, Yuste R, Zhuang X (2013) Nanotools for Neuroscience and Brain Activity Mapping. ACS Nano.
289. Alivisatos AP, Chun M, Church GM, Deisseroth K, Donoghue JP, Greenspan RJ, McEuen PL, Roukes ML, Sejnowski TJ, Weiss PS, Yuste R (2013) The Brain Activity Map Science DOI: 10.1126/science.1236939
288. Payne A, Andregg M, Kemmish K, Hamalainen M, Bowell C, Bleloch A, Klejwa N, Lehrach W, Schatz K, Stark H, Marblestone A, Church G, Own CS, Andregg W (2013) Molecular threading: mechanical extraction, stretching and placement of DNA molecules from a liquid-air interface. PLoS One 8(7):e69058. PMID: 23935923
287. Kosuri S, Goodman DB, Cambray G, Mutalik VK, Gao Y, Arkin AP, Endy D, Church GM. (2013) Composability of regulatory sequences controlling transcription and translation in E. coli. PNAS. PMID: 23924614
286. DiCarlo J, Norville J, Mali P, Rios X, Aach J, Church G (2013) Genome Engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Res. PMID: 23460208
285. Rockwell G, Guido NJ, Church GM (2013) Redirector: designing cell factories by reconstructing the metabolic objective.PLoS Comput Biol. 2013 Jan;9(1):e1002882. PMID: 23341769
284. Baker S, Joecker A, Church G, Snyder M, West J, Salzberg S, Worthey E, Smith T, Wang J, Reid JG (2012) Genome interpretation and assembly -- recent progress and next steps. Nat Biotechnol. 2012 Nov;30(11):1081-3. PMID: 23138307
283a. Mee MT, Wang HH. (2012) Engineering ecosystems and synthetic ecologies.Mol Biosyst. 8(10):2470-83.
283. Wang HH, Mee MT, Church GM (2013) Applications of Engineered Synthetic Ecosystems. Chapter 17. Synthetic Biology. doi
282. Church GM (2012) Reading and writing omes MSB 9:642. PMID: 23340848
281a. Esvelt KM, Wang HH (2012) Genome-scale engineering for systems and synthetic biology MSB 9:641. PMID: 23340847
281. Lajoie MJ, Kosuri S, Mosberg JA, Gregg CJ, Zhang D, Church GM (2013) Probing the limits of genetic recoding in essential genes. Science 342: 361-3. PMID: 24136967
280. Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FI (2013) Genomically Recoded Organisms Impart New Biological Functions. Science 342: 357-60. PMID: 24136966
279. Mali P, John Aach J, Lee J, Levner D, Nip L, Church GM (2013) Barcoding cells using cell-surface programmable DNA-binding domains. Nature Methods. Supplement
278. Yang L, Guell M, Byrne S, Yang J, De Los Angeles A, Mali P, Aach J, Briggs A, Rios X, Huang PY, Daley G, Church GM (2013). Optimization of Scarless Human Stem Cell Genome Editing. Nucleic Acids Res. PMID: 23907390
277. Plank M, Hu G, Silva AS, Wood SH, Hesketh EE, Janssens G, Macedo A, de Magalhaes JP, Church GM (2012) An analysis and validation pipeline for large-scale RNAi-based screens. Scientific Reports 3:1076. doi: 10.1038/srep01076. PMID: 23326633
276. Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville J, Church GM (2013) RNA-guided human genome engineering via Cas9. Science, Jan 3. 339(6121): 823-6. Supplement PMID: 23287722 Addgene: hCas9, D10A, Vector
275a. Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F (2013) Multiplex Genome Engineering Using CRISPR/Cas Systems. Science Jan 3. PMID: 23287718
275. Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P(2012) Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. Nat Chem. 4(10):832-839. PMID: 23000997
274a. Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Yiming Chang Y, Li JB, Senaratne TN, Williams BR, Rouillard JM, and Wu CT (2012) A versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes. PNAS 109: 21301-6. PMID: 23236188
274. Zamft B, Marblestone A,Kording K, Schmidt D, Martin-Alarcon D, Tyo K, Boyden E, Church GM (2012) Measuring Cation Dependent DNA Polymerase Fidelity Landscapes by Deep Sequencing PLoS One 7(8):e43876, PMID: 22928047Supplementary data
273. Rios X, Briggs AW, Christodoulou D, Gorham JM, Seidman JG, Church GM (2012) Stable gene targeting in human cells using single-strand oligonucleotides with modified bases. PLoS One. 7:e36697. PMID: 22615794
272. Dreyfuss JM, Levner D, Galagan JE, Church GM, Ramoni MF (2012) How accurate can genetic predictions be? BMC Genomics 13(1):340. PMID: 22827772
271. Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. (2012) Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res. PMID: 22740649
270. Church GM, Regis E (2012) Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves 288 pages. Basic Books, publisher.
269. Drukier A, Freese K, Spergel D, Cantor C, Church G, Sano T (2012) New Dark Matter Detectors using DNA for Nanometer Tracking ArXiv.
268. Alivisatos AP, Chun M, Church GM, Greenspan RJ, Roukes ML, Yuste R (2012) The Brain Activity Map Project and the Challenge of Functional Connectomics. Neuron. 74: 970-4. PMID: 22726828
267a. Cong L, Zhou R, Kuo YC, Cunniff M, Zhang F. (2012) Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun. 3:968. PMID: 22828628
267. Church GM, Gao Y, Kosuri S (2012) Next-generation Digital Information Storage in DNA. Science DOI: 10.1126/science.1226355 supplement PMID: 22903519
266a. Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F (2012) A transcription activator-like effector toolbox for genome engineering. Nat Protoc. 7(1):171-92. PMID: 22222791
266. Zhu J, Larman HB, Gao G, Somwar R, Zhang Z, Laserson U, Ciccia A, Pavlova N, Church G, Zhang W, Kesari S, Elledge SJ (2013) PLATO: Parallel Analysis of in vitro Translated ORF libraries. Nature Biotech. doi: 10.1038/nbt.2539. PMID: 23503679
265. Larman HB, Laserson U, Querol L, Verhaeghen K, Solimini NL, Xu G, Klarenbeek PL, Church GM, Hafler DA, Plenge RM, Nigrovic PA, De Jager PL, Weets I, Martens GA, O'Connor KC, Elledge SJ (2013) PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. J Autoimmun. 43:1-9. PMID: 23497938
264. Gu L, Li C, Aach J, Hill DE, Vidal M, Church GM (2014) Submitted.
263. Chou MF, Prisic S, Lubner JM, Church GM, Husson RN, Schwartz D (2012) Using bacteria to determine protein kinase specificity and predict target substrates. PLoS One 7(12):e52747. PMID: 23300758
262. Mosberg Ja, Gregg CJ, Lajoie MJ, Wang HH, Church GM (2012) Improving Lambda Red Genome Engineering via Rational Removal of Endogenous Nucleases. PLoS One 7(9):e44638. PMID: 22957093
261. Lajoie MJ, Gregg CJ, Mosberg JA, Washington GC, Church GM (2012) Manipulating Replisome Dynamics to Enhance Lambda Red-Mediated Multiplex Genome Engineering Nucleic Acids Research 40(22):e170. PMID: 22904085
260. Rho J, Kuoy E, Huo H, Kim KY, Lensch MW, Bang D, Church GM, Daley GQ, Park IH (2012) Analysis of Retroviral Insertion Sites for Generation of Transgene-Free Human Induced Pluripotent Stem Cells. submitted to PLoS One.
259. Eroshenko N, Kosuri S, Marblestone AH, Conway N, Church GM (2012) Gene Assembly from Chip-Synthesized Oligonucleotides. Current Protocols in Chemical Biology 4: 1-17.
258a. Kosuri S, Sismour M (2012) When It Rains, It Pores. ACS Synth. Biol. 2012, 1, 109-110. (dx.doi.org/10.1021/sb300015f)
258. Alon S, Mor E, Vigneault F, Church G, Locatelli F, Galeano F, Gallo A, Shomron N, Eisenberg E. (2012) Systematic identification of edited microRNAs in the human brain. Genome Res. PMID: 22499667
257. Vigneault F, Ter-Ovanesyan D, Alon S, Eminaga S, C Christodoulou D, Seidman JG, Eisenberg E, Church G (2012) High-Throughput Multiplex Sequencing of miRNA. Curr Protoc Hum Genet. Chapter 11: Unit 11.12.
256. Laserson U, Vigneault F, Gadala-Maria D, Yaari G, Uduman M, Vander Heiden J, Kelton W, Jung ST, Liu Y, Laserson J, Chari R, Lee J, Ido Bachelet I, Brendan Hickey B, Lieberman-Aiden E, Hanczaruk B, Simen BB, Egholm M, Koller D, Georgiou G, Kleinstein S, Church GM (2014) High-resolution antibody dynamics of vaccine-induced immune responses. Submitted to PNAS.
255. Jewett MC, Fritz BR, Timmerman LE, Church GM (2013) In vitro integration of ribosomal RNA synthesis, ribosome assembly and translation. MSB 9:678. PMID: 23799452
254. Carr PA, Wang HH, Sterling B, Isaacs FJ, Xu G, Church GM, Jacobson JM (2012) Enhanced Multiplex Genome Engineering through Co-operative Oligonucleotide Co-selection. Nucleic Acids Res. PMID: 22638574
253. Juhas M, Eberl L, Church GM (2012) Essential genes as antimicrobial targets and cornerstones of synthetic biology. Trends Biotechnol. PMID: 22951051
252. Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, DeWerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, Haynes KA, Viel A, Brenner TJ, Mathews S, Church GM, Shah JV, Silver PA (2012) A BioBrick compatible strategy for genetic modification of plants. J Biol Eng. 6:8. PMID: 22716313
251. Ball MP*, Thakuria JV*, Zaranek AW*, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow M, Cano C, Chou MF, Chung WK, Douglas SM, Estep P, Gore A, Hulick P, Labarga A, Lee J, Lunshof J, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters B, Raman AM, Reinhoff HY, Robasky K, Wheeler M, Vandewege W, Vorhaus D, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM (2012) A Public Resource Facilitating Clinical Use of Genomes. Proc Natl Acad Sci USA. 109(30):11920-7 (inaugural article) PMID: 22797899
250. Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, Jiang Y, Dahl F, Tang YT, Hass J, Robasky K, Zaranek AW, Lee JH, Ball MP, Peterson JE, Perazich H, Yeung G, Liu J, Chen L, Pothuraju K, Konvicka K, Tsoupko-Sitnikov M, Pant KP, Ebert J, Nilsen G, Baccash J, Halpern AL, Church GM, Drmanac R (2012) Accurate whole genome sequencing and haplotyping from 10-20 human cells. Nature 487: 190-195. (supplement)
249. Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM (2012) Genome-scale Promoter Engineering by Coselection MAGE. Nature Methods Apr 8. doi: 10.1038/nmeth.1971 PMID: 22484848
248. Wang HH, Huang PY, Xu G, Haas W, Marblestone A, Li J, Gygi S, Forster A, Jewett MC, Church GM (2012) Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multi-enzyme catalysis. ACS Synthetic Biology 1(2):43-52. PMID: 22737598
247. Thakuria JV, Zaranek AW, Church GM, Berry GT. (2012) Back to the future: From genome to metabolome. Hum Mutat. 2012 Mar 16. doi: 10.1002/humu.22073. PMID: 22431014
246. Douglas SM, Bachelet I, Church GM (2012) A logic-gated nanorobot for targeted transport of molecular payloads. Science 335, 831-834. PMID: 22344439. Supplement
245. Gianoulis TA, Griffin MA, Spakowicz DJ, Dunican BF, Alpha CJ, Sboner A, Sismour AM, Kodira C, Egholm M, Church GM, Gerstein MB, Strobel SA. (2012) Genomic Analysis of the Hydrocarbon-Producing, Cellulolytic, Endophytic Fungus Ascocoryne sarcoides. PLoS Genet. 8(3):e1002558. PMID: 22396667
244. Nelson FK, Snyder M,Gardner AF, Hendrickson CL, Shendure JA, Porreca GJ, Church GM, Ausubel FM, Ju J, Kieleczawa J, Slatko BE (2011) Overview of DNA sequencing strategies. Curr Protoc Mol Biol. Chapter 7:Unit7.0.