4thReunion of FFCSA Club in Guangzhou
Date: November18th-20th, 2011
Hotel: Guangzhou Yuan Yang Hotel
November 18th, 2011 (Friday)
Registration, Hotel
18:30 Banquet:Guangzhou Yuan Yang Hotel. (Hosted by GIGCAS)
November 19th, 2011 (Saturday)
8:30 - 9:00 Opening Ceremony
Professor XU Yigang, Director of Guangzhou Institute of Geochemistry, CAS.
Professor ZHANG Gan, Foreign affairs of Guangzhou Institute of Geochemistry
9:00 - 9:30 Oral Presentation 1---"How to be somebody in social network". XIE Gaogang (Promotion 2005)
9:30 - 10:00 Oral Presentation 2 --- Geologicalresources of gas hydrate in the Qilian Mountain permafrost, Qinghai province, the northwest of China". LU Zhengquan ( Promotion 2005)
10:00 - 10:30 Photo & Break
10:30 - 11:00 Oral Presentation 3 --- 'Non-Bragg band gaps and light manipulation of composite structures with metamaterials'JIANG Haitao (Promotion 2006) –Gilles Kahn Prize 2011
11:00 - 11:30 Oral Presentation 4 --- "Correlation Between Structure, Acidity and Catalytic Performance of WOX/Al2O3 Catalysts " CHEN Xueying (Promotion 2008)
11:30 - 12:00 Oral Presentation 5 Graph Theory with applications
--- WANG Guanghui (Promotion 2007)
12:00 Lunch
13:30 - 14:00 Oral Presentation 6 --- Changes of the brain in elderly
ZHU Yicheng (Promotion 2008)
14:00 - 14:30 Oral Presentation 7 -A genome-wide association study of transcript isoformvariation in Asthma HUANG Jinyan (Promotion 2009)
14:30 - 15:00 OralPresentation 8 ---Investigation of biogenic volatile organic compounds oxidationunder atmospheric simulated conditions François BERNARD (French post-doc in GIGCAS)
15:00 - 15:15 Break
15:15 - 16:45 Round Table discussion between French and Chinese companies
Philippe Garderet –Aréva
Pierre Renard et Y.Tsouderos –Laboratoire Servier
16:45 - 17:40 Visiting Guangzhou Institute of Geochemistry, CAS
18:00 Banquet (Yumin Seafood Restaurant)
November 20th, 2011 (Sunday)- 10th Anniversary of the FFCSA
9:00 – 11:00 The Past and The Future of the FFCSA
French and Chinese Personalities (Minister of Health CAS, CSC, French Embassy, French Consulate inGuangzhou, representant Presidence of the French Republic in France…)
Professor Chen Zhu, Minister of Health
Monsieur Bernard Belloc, Scientific adviser of the French Republic Presidency
Madame YANG Xinyu, Secretary Deputy General of the China Scholarship Council
Professor Jacques Caen, co president Founder of the scientific council of the FFCSA
Anne-Sophie Broussier, co president of the FFCSA’s Club
Professor Changgeng Ruan, Member of the Chinese Academy of Engineering
Professor Laurent Degos, co president of the Scientific council of the FFCSA
Representants of the French Embassy in Beijing, and the French Consulate in Guangzhou
11.30 – 12:00 5thGilles Kahn-Total Prize 2011 awarded to Jiang Haitao
Professor Yves Quéré , co president of the scientific Council of the FFCSA
Monsieur Jean François Minster, Scientific Director Total
12:00 Lunch
Afternoon
Departure
远洋酒店（远洋大厦）YUAN YANG HOTEL
地址：广州市天河龙口东路6号，Longkou Dong Lu 6, Tianhe, Guangzhou, China
邮编Post code: 510630；电话Tel: (86-20)-61082888；传真Fax: (86-20)-87597988
到达路线：1、机场乘地铁至“体育西路”站-转地铁3号线至“岗顶站”A出口按以下图示线路前行200米；Airport: By metro to the station “Ti Yu Xi Lu”, then exchange to metro Line 3 to the station “Gang Ding”, take the “Exit A” and walk about 200m following the map below.
2、火车（东）站：乘地铁至“体育西路”站-转地铁3号线至“岗顶站”A出口按以下图示线路前行200米；Railway Station: Take the metro to the station “Ti Yu Xi Lu”, then following the instructions as above.
November 19th, 2011 (Saturday)
Presentation 1
"How to be somebody in social network"
XIE Gaogang (Promotion 2005)
Institute of Computing Technology –Chinese Academy of Sciences, Beijing, China
INRIA, Domaine de Voluceau,Rocquencourt, Le Chesnay, France.
The past few years has witnessed the rapid development of Web 2.0 services, particular the Online Social Networks (OSNs), which has been important platforms for informationdiffusion. The per day visit count of Facebook has reached to 230 million, which makes the site become as the second biggest website following Google. The video view count per day on YouTube is more than 100 million. Such big numbers clearly demonstrate the influences. How do user behavior? How the information is diffused on such platforms? The answers to these questions can help the design of efficient advertisement through viral marketing and effective public opinion control. The network deployment and future Internet design can also be benefited.
In this talk, three different kinds of social network platform have been investigated: (1) the characteristics of user interactivities and interaction networks in social networks (Facebook, Renren); (2) the social relationship between videos and users in a social video sharing system YouKu; (3) the process and models for tweets’ diffusion in Microblog platform. Applying the above results, a fast information diffusion mechanism and a friend recommendation system are proposed.
随着近年来Web 2.0技术的飞速发展，在线社交网络（Online Social Network，简称OSN）已经成为人们交流信息的重要平台。社交网站Facebook每日访问量已达2.3亿，成为仅次于Google全球第二大网站，而视频分享网站YouTube每日的视频观看量也已经超过了1亿。鉴于在线社交网络的巨大影响力，分析在线社交网络中的用户活动特征与信息传播模式，对于进行有效的广告推送、舆情控制，构建合理的网络部署以及设计未来互联网体系结构都具有十分深远的意义。
本报告将对三类不同的社交网络平台的研究进行介绍：（1）交友类网站（Facebook，Renren等）中用户之间的交互行为和交互网络特征；（2）视频分享系统（YouKu）中视频和用户之间的社会关联性；（3）微博平台中微博文的转发过程及其模型。应用上述成果，建立了一种快速有效地信息传播机制，大幅提升了信息的传播速度；设计了视频分享系统中好友推荐系统，增强网络连通性，使得用户能更容易地得到感兴趣视频。
Presentation 2
Geologicalresources of gas hydrate in the Qilian Mountain permafrost, Qinghai province, the northwest of China".
LU Zhengquan ( Promotion 2005)
Institute of Mineral Ressources, Chinese Academy of Geological Sciences, Beijing, China
Docteur Nabil Sultan, IFREMER, Plouzane, France
Gas hydrate or hydrate, known as ‘flammable ice’ due to its ice-like appearance and being vulnerable to burn, is a kind of crystalloid solid matter formed from water and gas molecules (e.g., methane, ethane, propane, isobutene, hydrogen sulfide, carbon dioxide etc.) under low temperature (generally around 273.15K) and highpressure(generally higher than 3~5MPa) conditions when gas concentration is greater than its solubility. Because of its great energy significance as well as its potential environmental effect and possible disastrous impact, gas hydrate currently becomesa hot spot research field.
Since the permafrost-based gas hydrate drilling project conducted by China Geological Survey in 2008, gas hydrate samples have been successfully obtained in the Muli permafrost within the Tianjun county of the Qinghai province, which was the first to fulfill the breakthrough in gas hydrate exploration on the China’s continent. Gas hydrates occurred in mudstone, oily shale, siltstone, fine sandstone etc., which appeared not closely related to sandstone; they mainly occurred in the fissure and pore space, but were strongly controlled by fissures; they were vertically discontinuous and horizontally irrelatively arranged; they occurred in the range of 130 to 400m. Gases from gas hydrate are mainly composed of methane with some ethane and propane, and minor heavy hydrocarbons, characteristic of wet gas; the gas composition and isotope values are preferably of thermal genesis with secondarily of microbial genesis (acetate fermentation); gases of thermal genesis are predominantly from crude oil cracking or in association with crude oil generation, and minor or trace of them are associated with condensate gases, coal-typed gases, kerogen cracking gases; namely gas hydrate is closely related to oil-typed gases rather than coal-typed gases (actually kinds of oil indications are visible while coal-bed methane is not well developed within intervals of gas hydrate occurrence). Based on field observation and indoor analyzed results, gas hydrate resource in the pore space of sandstone and that within the fissure are estimated to be about 6.24×104m3 and 8.80×105m3 gases in the drilling area of 4.0×105m2 respectively, with the total of about 9.42×105m3 gases.
中国西北部青海省祁连山冻土区天然气水合物地质资源
天然气水合物（简称水合物）因外貌像冰，点火可以燃烧，俗称“可燃冰”，是由水和重量轻的气体分子（如甲烷、乙烷、丙烷、异丁烷、硫化氢、二氧化碳等）在低温（70～350 K，一般273.15K左右）、高压（一般大于3～5MPa）、气体浓度大于其溶解度条件下形成的一种结晶状固体物质。因其巨大的能源意义，加之潜在的环境效应及可能的灾害影响，天然气水合物已成为当前调查研究的热点。
中国地质调查局自2008年实施冻土天然气水合物钻探工程以来，成功地在青海省天峻县木里镇附近冻土区中钻获到天然气水合物实物样品，首次在中国陆域实现天然气水合物的勘查突破。天然气水合物主要产于泥岩、油页岩、粉砂岩、细砂岩等层段中，与砂岩产出关系不密切；常出露在岩层的裂隙和孔隙中，受裂隙的控制较为明显；纵向上分布不连续，主要出现在井下130~400 m之间，横向上无明显的对比关系。天然气水合物气体组分以甲烷为主，同时含有一定量乙烷和丙烷，并含有少量其它重烃气体，具湿气特征；气体组成和同位素值显示天然气水合物的气源以热解成因为主，夹少量微生物成因（醋酸根发酵），其中，热解成因气主要与原油裂解气、原油伴生气有关，少部分与凝析油伴生气、煤成气、干酪根裂解气有关，即天然气水合物的气体来源与油型气密切相关，而与煤型气关系不大（实际上，天然气水合物产出层段见有各种油气显示现象，而煤层气普遍不发育）。基于野外地质观测和室内分析测试结果，在钻探区约4.0×104m2面积内，计算得到砂岩孔隙中天然气水合物资源量约为6.24×104m3天然气，破碎岩层裂隙中的天然气水合物资源量约为8.80×105m3天然气，总的资源量约为9.42×105m3天然气。
Presentation 3
Non-Bragg band gaps and light manipulation of composite structures with metamaterials.
JIANG Haitao (Promotion 2006)
Pohl Institute of Solid State Physics, Tongji University, Shanghai, RP China
Laboratoire du Professeur Gérad Tayeb, Université Paul Cézanne Marseille III
Non-Bragg band gaps and light manipulation of composite structures with metamaterials
Abstract:Wave interferences in composite structures can lead to many fascinating and fundamental physical phenomena such as Bragg bandgaps and Anderson localization. However, all the phenomena in usual composite structures occur only for the interference of propagating waves and dependonthe detail of the interferenceprocess. To expand our ability in controlling the flow of light, we introduce double-negative metamaterials or two types of single-negative metamaterials into the composite structures. In these composite structures, we can not only ignore the detail of the interference, but also extend the interference of propagating waves to that of decaying waves. In particular, non-Bragg bandgaps that are robust against incident directions, thickness scaling-change and fluctuation can appear, which not only provide us more freedom in light manipulation, but also provide new mechanisms for the design ofphotonic devices.
摘要：波在复合结构中的干涉能产生布拉格能带和安德森局域等许多有趣而基本的物理现象。然而，在传统的复合结构中产生的现象均来自于传播场的干涉并且依赖于干涉过程中的细节。为了更好地操控光，我们在复合结构中引入双负或两种单负特异材料。在这些含特异材料的复合结构中，我们不仅可以忽略干涉的细节，而且将传播场的干涉拓展至迅衰场的干涉。特别地，在这些结构中可以出现对入射角度，厚度标度变化和涨落均不敏感的非布拉格能带。这些非布拉格能带不仅为我们操控光提供了更多的自由度，而且为我们设计光子器件提供了崭新的机理。
Presentation 4
Correlation between structure, acidity and catalytic performance of WOX/Al2O3 catalysts
CHEN Xueying (promotion 2008)
Department of Chemistry, Fudan University, Shanghai , RP China.
Laboratoire de catalyse et Spectrochimie UMR 6506 CNRS/ENSICAEN-Professeur Jean-Pierre Gilson.
WOX/Al2O3 catalysts have already been the focus of many studies dealing with their structure, acidity or catalytic performance. However a very limited number of studies have established a quantitative relationship among these three parameters. Thus, ourstudy undertakes a detailed analysis of the relationships between surface structure, acidity of WOx/Al2O3 catalysts and the activity of the solids for isopropanol dehydration. Surface W species were analyzed as a function of the W surface density using Raman and Infrared spectroscopy. The acidity of the solids was investigated by two different probe molecules (lutidine and CO). Finally a direct relationship was established between the catalytic activity, abundance of relatively strong Brønsted acid sites and the development of the most condensed W species.The above findings are clearly of importance for the understanding of the nature of active sites in heterogeneous catalysts.
WOX/Al2O3催化剂的结构、酸性和催化性能一直是研究热点。但是，目前仅有数量非常有限的工作研究了以上三个参数之间的定量关系。因此，我们采用拉曼和红外光谱详细研究了WOX/Al2O3催化剂的表面结构，采用二甲基吡啶和CO两种不同的探针分子研究了催化剂的酸性质，以异丙醇脱水为探针反应研究了催化剂的催化活性，对催化剂的活性、B酸酸量和多聚态WOx物种之间的关系建立了直接关联。上述发现对理解多相固体酸催化剂的活性位的本质具有重要意义。
Presentation 5
Graph Theory with applications
WANG Guanghui (Promotion 2007)
WANG Guanghui, School of Mathematics, Shandong University Jinan， Shandong,
Ecole Centrale Paris, laboratoire des Mathématiques Appliquées aux Systèmes, Equipe MASBIO.
Graphs can be used to model many types of relations and process dynamics in physical, biological and social systems. Many problems of practical interest can be represented by graphs.This talk is intended as an introduction to graph theory. We introduce the history of graph theory and present some basic concepts and examples in graph theory. Also we list a wide variety of its applicationsto real-world problems.
图论及其应用
王光辉
数学学院
济南，250100，山东
自然界和人类社会中的很多关系都可以用图来表示，图论是研究物理学，生命科学以及社会科学的一个重要的数学工具。我们将介绍图论的研究历史和图论中的基本概念和问题；同时我们也将举例说明图论在实际生活中的应用。
Presentation 6
Changes of the brain in elderly
ZHU Yicheng (Promotion 2008)
Zhu Yicheng, Department of neurology, Pekin Union Medical College Hospital , Beijing, China.
Centre de références pour les maladies rares des vaisseaux du cerveau (CERVCO), Hôpital Lariboisière, Professeur Hugues Chabriat
The normal adult brain undergoes considerable morphological changes with aging and the pattern of changes is highly heterogeneous. Studying these changes is paramount to differentiate normal age-related brain variations from the effects of neurodegenerative diseases and cerebral vascular diseases affecting brain structure in the elderly. Considerable progress has been made in this research area during the past few decades, given the availability of noninvasive imaging tools such as magneticresonance (MR). As a result, these cerebral imaging dramatically enriched our understanding of age-related disorders of the central nervous system (CNS) and made it possible to predict the functional performances and quality of life in elderly people .
正常成年人脑会随着衰老发生显著的结构改变，并且这种改变具有明显个体差异。对衰老的脑结构改变进行研究，对鉴别神经系统变性病、脑血管病和正常年龄相关脑改变具有重要意义。近20年来，无创神经影像技术（如核磁共振技术）的发展，极大地丰富了我们对年龄相关的神经系统改变的认识，同时也使对老年人功能障碍和生活质量的预测成为可能
Presentation 7
A genome-wide association study of transcript isoformvariation in Asthma
HUANG Jinyan (Promotion 2009)
Huang Jinyan, School of Life Science and Technology, Tongji University , Shanghai
Laboratoire de Bioinformatique de la Fondation Jean Dausset –CEPH en collaboration avec le Centre National de Génotypage sous la direction de Monsieur Mark Lathrop
A genome-wide association study of transcript isoform in Asthma
Jinyan HUANG1, G Mark Lathrop2, William O C Cookson3
1School of life science, Tongji University, 200092 Shanghai, China 2CEA, Centre National de Génotypage, 91000 Evry, France and 3National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
Email:
We have performed a genome-wide analysis of common genetic variation controlling differential expression of transcript isoform using a comprehensive exon tiling microarray covering 19,126 genes in 400 children from families recruited through a proband with asthma. Based on the genotyped 301,173 SNPs, 6,032,596 SNPs are imputed using 1000 genome CEU template. Expression quantitative trait loci from measurements were identified in Epstein-Barr virus–transformed lymphoblastoid cell lines. 528 significant associated genes are annotated as splicing genes by Ensembl or UCSC database. 48 of genes are associated by asthma risk SNPs. The results demonstrate that eSNPs regulated gene expression, 21.6% by Methylation/Acetylation 18.3% by DNaseI/FAIRE, 11% by Transfactor and 7.8% by RNA polymerase II/III, 3.4% by cis-regulatory element and 1.3% by miRNA, separately. The regulatory effects of genetic variation in human population are far more complex than previously observed.
Key words:Expression Quantitative Trait Locus (eQTL), genome-wide association study (GWAS), Asthma
支气管哮喘中转录异构体变化全基因组关联研究
通过招募400名支气管哮喘儿童的家庭样本，我们采用EB病毒转化的淋巴母细胞系进行了全基因组基因表达定量性状位点分析。基因表达水平的测量采用Affymetrix Human Exon 1.0 ST芯片。基于301,173个Illumina芯片测得单核苷酸多态性，我们采用1000基因组欧洲样本为模板，推测出6,032,596个单核苷酸多态性用为表达定量性状位点分析。528个显著关联的基因转录异构体被发现，其中48个基因是和有哮喘风险的单核苷酸多态性关联。分析结果表明，单核苷酸多态性调控基因表达，21.6%可能是通过甲基化/乙酰化，18.3％通过DNaseI/FAIRE，11％通过转录调控因子，7.8%通过RNA聚合酶II/III，3.4％通过顺式调控元件，1.3％通过miRNA。
关键词：表达定量性状位点（eQTL），全基因组关联研究（GWAS），哮喘
Presentation 8
Investigation of biogenic volatile organic compounds oxidationunder atmospheric simulated conditions
François BERNARD (French post-doc in GIGCAS)
The atmosphere is the recipient of chemical species emitted from various sources as well anthropogenic as biogenic sources. The continuing emission and the occurrence of chemical processes inducing transformation of these species lead ultimately to the formation of secondary pollutants such as ozone and other photooxidants and particles, altering air quality and climate.
As well established, vegetation is considered as the main emission source of volatile non-methane organic compounds in the atmosphere on a global scale, also called biogenic volatile organic compound (BVOC). Emission inventories indicate that BVOCs exceed anthropogenic components on regional and global scales (up to a factor of ~ 10). Isoprene (C5H8) is the major VOCs emitted from vegetation accompanied with the emission of terpenes (C10H16, C15H24, ...). As unsaturated hydrocarbons, they are very reactive with the major atmospheric oxidants such ozone (O3), hydroxyl (OH) and nitrate (NO3) radicals, impacting the tropospheric composition by generating a variety of oxygenated products and secondary organic aerosol (SOA). Therefore, laboratory data on the atmospheric fate of BVOCs are of crucial importance to understand field observations and further, to improve the quality of the atmospheric chemical models.
In order to define the atmospheric fate of these BVOCs, atmospheric chambers and flow reactor techniques have been used in order to simulate chemical and physical processes occurring in the atmosphere.
During this talk, a global description of the degradation of selected BVOCs by the gas-phase reactions with ozone and OH radicals will be given including the determination of rate constants and the oxidation products formed. In addition, the potential of these BVOCs by reaction with ozone to form SOA particles will be given. Impact of the degradation of these compounds on air quality will be further discussed.
Etude de l’oxydation de composés organiques volatils biogéniques
sous des conditions atmosphériques simulées.
L’atmosphère contient de nombreuses espèces chimiques issues des sources anthropogéniques et biogéniques. L’émission continue et l’occurrence de processus chimiques contribuant à la transformation de ces espèces mènent à terme à la formation de polluants secondaires tels que l’ozone et autres photooxydants et des particules, qui détériorent la qualité de l’air et le climat.
Bien reconnue aujourd’hui, la végétation est considérée comme la principale source d’émission de composés organiques volatils non-méthaniques dans l’atmosphère à l’échelle globale, aussi appelée composés organiques volatils biogéniques (COVB). Les inventaires d’émissions indiquent que les composés d’origine biogénique excèdent ceux émis par les activités humaines aux échelles régionale et globale (jusqu'à un facteur 10 environ). L’isoprène (C5H8) est le principal COV émis a partir de la végétation accompagnée de l’émission de terpènes (C10H16, C15H24, ...). Porteurs de liaisons insaturées, ces composés sont très réactifs avec les principaux oxydants atmosphériques tels que l’ozone (O3), les radicaux hydroxyles (OH) et nitrates (NO3), affectant la composition troposphérique en générant une variété de produits oxygénés et d’aérosols organiques secondaires (AOS). Par conséquent, les données de laboratoire sont de première importance afin de comprendre les observations de terrains et d’améliorer par la suite la qualité des modèles de chimie atmosphérique.
Afin de définir le devenir atmosphérique des COVB, les dispositifs tels que les chambres de simulation et le réacteur à écoulement ont été utilisés afin de simuler les processus chimiques et physiques qui se déroulent dans l’atmosphère.
Au cours de cette présentation, sera donnée une description globale de la dégradation de quelques COVB par les réactions avec les radicaux OH et l’ozone en phase gazeuse, incluant la détermination de constante de vitesse et des produits d’oxydation formés. De plus, le potentiel de ces composés à former des AOSpar réaction avec l’ozone sera également présenté. L’impact de la dégradation de ces composés sur la qualité de l’air sera par la suite discuté.