Table 2S Results of QTLD analysis for all SNPs in the RERE gene region

Name / Position / allelesa / MAFb / HWEc / Role / P-value of QTLD test for
FN BMD / LS BMD / TR BMD
rs8627 / 8347201 / A/G / 0.473 / 1 / 3' UTR / 0.0955281 / 0.0113309 / 0.1984376
rs6678140 / 8371068 / C/T / 0.183 / 0.5407 / Intron / 0.3644835 / 0.9267845 / 0.7640297
rs11121179 / 8389978 / G/T / 0.232 / 0.3633 / Intron / 0.0022939 / 5.01E-06 / 0.0003273
rs11121181 / 8411272 / A/G / 0.182 / 1 / Intron / 0.6157124 / 0.5092684 / 0.4742838
rs301819d / 8436052 / A/G / 0.382 / 1 / Intron
rs11581328 d / 8442039 / A/G / 0.323 / 0.7173 / Intron
rs301810 / 8450654 / C/G / 0.205 / 0.246 / Intron / 0.0074797 / 0.00145 / 0.001272
rs1024197 / 8471324 / C/G / 0.477 / 1 / Intron / 0.4360497 / 0.1787707 / 0.2174755
rs4908761 / 8486485 / A/G / 0.477 / 1 / Intron / 0.4597103 / 0.1865217 / 0.2245952
rs6577497 / 8539933 / A/T / 0.273 / 0.0363 / Intron / 0.5423444 / 0.7406046 / 0.7250258
rs12405049 / 8560383 / C/T / 0.31 / 0.9136 / Intron / 0.9539689 / 0.7262315 / 0.4881624
rs6670508 / 8582183 / C/G / 0.482 / 1 / Intron / 0.4296801 / 0.1840406 / 0.222299
rs6701331 / 8604472 / A/C / 0.482 / 1 / Intron / 0.4296801 / 0.1840406 / 0.222299
rs11121207 / 8616114 / A/C / 0.327 / 1 / Intron / 0.7411528 / 0.787871 / 0.698761
rs1463052 / 8635497 / A/G / 0.468 / 0.9274 / Intron / 0.6148043 / 0.3728229 / 0.2451201
rs6577514 / 8647009 / G/T / 0.463 / 0.7661 / Intron / 0.3249706 / 0.1797188 / 0.1073686
rs4908507 / 8673203 / C/T / 0.468 / 0.6336 / Intron / 0.292817 / 0.1396403 / 0.1257272
rs10864363 / 8701577 / G/T / 0.195 / 1 / Intron / 0.8640606 / 0.870323 / 0.7060307
rs953043 / 8708717 / C/T / 0.214 / 1 / Intron / 0.9254565 / 0.4863218 / 0.6264133
rs4908775 / 8728676 / A/G / 0.339 / 0.6478 / Intron / 0.7404016 / 0.9620498 / 0.765634
rs12403640 / 8752129 / C/T / 0.395 / 0.3017 / Intron / 0.636027 / 0.1352997 / 0.6095162
rs7513880 / 8773566 / A/G / 0.384 / 0.3427 / Intron / 0.5826912 / 0.208948 / 0.606589
rs6698830 / 8788811 / C/T / 0.394 / 0.3464 / Intron / 0.6052797 / 0.1332244 / 0.6208676
rs7520572 / 8805956 / A/G / 0.386 / 1 / Intron / 0.6591482 / 0.813686 / 0.2153453

a Major/minor

b Minor Allele Frequency

c P-values for test of deviation from Hardy-Weinberg equilibrium

dThese two markers were excluded from the QTLD analysis due to nominal evidence of population stratification (p<0.05)

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