Online Resource 1: Sensitivity analysis of estimated productivity losses per person of working age and employed at the time of head and neck cancer diagnosis calculated with the Human Capital Approach (HCA) and Friction Cost Approach (FCA) (2013 Euros)

Variable / Growth rate / Discount rate / Friction period
(weeks) / Mean / Std Dev / Minimum / Maximum
HCA base case (A) / 1.017 / 4% / €253,833 / 242,057 / 0 / 1,441,919
HCA Sensitivity B / 1.017 / 1% / - / €431,750 / 414,305 / 0 / 2,753,119
HCA Sensitivity C / 1.017 / 6% / - / €209,550 / 198,300 / 0 / 1,178,883
HCA Sensitivity D / 1.028 / 4% / - / €287,802 / 275,304 / 0 / 1,635,243
HCA Sensitivity E / 1.028 / 1% / - / €519,332 / 497,949 / 0 / 3,436,481
HCA Sensitivity F / 1.028 / 6% / - / €232,470 / 221,015 / 0 / 1,316,997
HCA Sensitivity G / 1.010 / 4% / - / €235,787 / 224,290 / 0 / 1,336,628
HCA Sensitivity H / 1.010 / 1% / - / €387,128 / 371,463 / 0 / 2,404,921
HCA Sensitivity I / 1.010 / 6% / - / €197,952 / 186,115 / 0 / 1,102,147
FCA base case / Manual: 10.1
Service: 9.9
Professional: 13.3 / €6,803 / 6,593 / 0 / 35,369
FCA sensitivity high / - / - / +20% / €8,119 / 7,932 / 0 / 42,442
FCA sensitivity low / - / - / -20% / €5,843 / 5,462 / 0 / 28,295

FCA, Friction Cost Approach; HCA, Human Capital Approach; Std Dev, Standard Deviation

Note: This is supplementary material for the manuscript entitled ‘Comparing Human Capital and Friction Cost approaches to estimating productivity losses: implications for decision-making using the case of head and neck cancer’ and is for online publication only.

Authors: Alison M Pearce, Paul Hanly, Aileen Timmons, Paul M Walsh, Ciaran O’Neill, Eleanor O’Sullivan, Rachael Gooberman-Hill, Audrey Alforque Thomas, Pamela Gallagher, Linda Sharp

Corresponding author: Alison Pearce, National Cancer Registry Ireland,