OIE RL for New Castle Disease Kang-Seuk Choi Korea (Rep. Of)

OIE RL for «New Castle Disease» – «Kang-Seuk Choi » – «Korea (Rep. of)»

OIE Reference Laboratory Reports
Activities in 2012

Name of disease (or topic) for which you are a designated OIE Reference Laboratory: / Newcastle disease
Address of laboratory / Newcastle disease laboratory
Animal Plant and Fisheries Quarantine & Inspection Agency (QIA), Ministry for Food, Agriculture, Forestry and Fisheries (MIFAFF)
175 Anyang-ro, Manan-gu, Anyang, Gyeonggi,
430-757, Republic of Korea
Tel.: / (82) 31-467-1821
Fax: / (82) 31-467-1814
e-mail address: /
website: /
Name (including Title) of Head of Laboratory (Responsible Official): / Dr. YongHo ParkDVM, MS, PhD
QIA Commissioner
Name(including Title and Position) of OIE Reference Expert: / Dr. Kang-Seuk ChoiDVM, MS, PhD
Chief of Newcastle disease laboratory
Date of submission to the OIE / January 2013

Instructions

This form should be used by an OIE Reference Laboratory to report activities that took place from January through December of the past year (2012), unless otherwise stated, and must be submitted by the end of January every year.

Only those activities that concern the disease (or topic) for which the laboratory is recognised by the OIE should be mentioned. The questionnaire structure follows the Terms of Reference (ToRs) for OIE Reference Laboratories, available at:

EachToR(blueitalicised text)has been placed as a heading covering the group of questions related to it.

Please note the reditalicisedtext is given as guidance and should be deleted from your report and substitute with your data. Examples are based onpast Annual Reports or have been invented.

The questionnaire represents a means of gathering information on activities carried out by OIE Reference Laboratories and making it available to OIE Member Countries and to the OIE Reference Laboratory network.

This annual report will remain available for consultation on the OIE web site:

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ToR:To use, promote and disseminate diagnostic methods validated according to OIE Standards

Test recommended by the OIE / Total number of test performed last year
Indirect diagnostic tests / Nationally / Internationally
HI / 2240 / 33
Direct diagnostic tests / Nationally / Internationally

Egg inoculation

/ 753 / 151

RT-PCR

/ 30 / 177

Sequencing RT-PCR

/ - / 20

ToR:To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards.

Tostore and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens or disease.

2.Did your laboratory produce or store imported standard reference reagentsofficially recognised by the OIE or other international bodies?

Yes No

3.Did your laboratory supply standard reference reagentsto OIE Member Countries?

Yes No

4.Did your laboratory produce diagnostic reagents other than the OIE-approved standard reference reagents?

Yes No

5.Did your laboratory produce vaccines?

Yes No

6.Did your laboratory supply vaccines to OIE Member Countries?

Yes No

ToR:To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases

7.Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease?

Yes No

8.Didyour laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease?

Yes No

Name of the new test or diagnostic method or vaccine developed / Description and References (Publication, website, etc.)
rNDV HN -based HI test / Choi et al.(2013).Preparation and diagnostic utility of a hemagglutination inhibition test antigen derived from the baculovirus-expressed hemagglutinin-neuraminidase protein gene of Newcastle disease virus. . J. Vet. Sci. In press.
Live Newcastle disease vaccine / Kim et al.(2012). Protective effects of a live Newcastle disease virus NDRL0901 vaccine strain in chickens. J. Vet. Sci. 52(3) (suppl):254, 2012.

ToR:To provide diagnostic testing facilities, and, where appropriate, scientific and technical advice on disease control measures to OIE Member Countries

9.Did your laboratory carry out diagnostic testing for other OIE Member Countries?

Yes No

Name of OIE Member Country seeking assistance / Date
(dd/mm) / No. samples received for provision of diagnostic support (i.e. from surveillance campaign) / No. samples received for provision of confirmatory diagnoses
Cambodia / 7/6 / 200 / -
Vietnam / 3/12 / 48 / -
Vietnam / 18/5 / 8
Vietnam / 14/2 / 5

10.Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country?

Yes No

Name of the OIE Member Country receiving a technical consultancy / Purpose / How the advice was provided
Veterinary Research Institute, Malaysia / Vaccination and preventive measures for control of Newcastle disease in Malaysia / In loco
National Veterinary Research Institute, Cambodia / Sampling for diagnosis of Newcastle diseaseinpoultry / In loco
National Center for Veterinary Diagnsosis, Vietnam / Molecular epidemiology of Newcastle disease in Vietnam / In loco
Hanoi University of Agriculture, Vietnam / Laboratory identification of Newcastle disease and other viral pathogens / In loco and remote assistance
Indonesian Veterinary Drugs Association, Indonesia / Epidemiology and diagnosis of Newcastle disease and other viral pathogens / In loco
Inbdonesian Research Center for Veterinary Science, Indonesia / Diagnosis of major avian viral diseases by RT-PCR or PCR assays / In loco

ToR:To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations

11.Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries other than the own?

Yes No

Title of the study / Duration / Purpose of the study / Partners (Institutions) / OIE Member Countries involved other than your country
Studies on molecular epidemiology of NDV and AIV in Cambodia / 2 years / Monitoring of NDV/AIV circulating in Cambodia / National Veterinary Research Institute / Cambodia
Comparative studies for AIV and NDV between Korea and Vietnam / 2 years / Monitoring of NDV/AIV circulating in Vietnam / National Center for Veterinary Diagnsosis / Vietnam

ToR:To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases

12.Didyour Laboratory collect epizootiologicaldata relevant to international disease control?

Yes No

13.Didyour laboratory disseminate epizootiologicaldata that had been processed and analysed?

Yes No

14.What method of dissemination of information is most often used by your laboratory?

(Indicate in the appropriate box the number by category)

a)Articles published in peer-reviewed journals:...... 5

b)International conferences:...... 4

c)National conferences:...... 7

d)Other:...... 0

a) Articles published in peer-reviewed journals:

Choi KS, Jeon WJ, Kye SJ, Yoon SS, Jeong W, Kim JY, Kwon JH. Seroprevalance of Newcastle disease virus in wild birds in Korea. Korean J. Poult. Sci. 39(2): 97-104, 2012.
Jae-Hong Kim, Haan-Woo Sung, Il-Hwan Kim, Eun-Kyoung Lee, Kang-Seuk Choi, Daniel Jack King. Characterization and comparison of the pathogenicity of viscerotropicvelogenic Newcastle disease virus isolates in Korea. KoreanJ.Vet. Res. 52(4) :000-000, 2012.
Mi-Ja Park, Soo-JeongKye, Ji-Ye Kim, Saeromi Kim, Hee-Jung Seul, Choi-Kyu Park, Kang-Seuk Choi. Generation and Biological Characterization of a Neutralization-Resistant Mutant of Newcastle Disease Virus.J. Bacteriol. Virol. 42(4):0-00, 2012.
Choi KS, Lee EK, Jeon WJ, Kwon JH, Lee JH, Sung HW. Molecular epidemiological investigation of lentogenic Newcastle disease virus from domestic birds at live bird markets in Korea. Avian Dis. 56(1):218-223. 2012.
Choi KS, Park MJ, Kye SJ, Kim JY, Kwon JH. Biological Properties of Vero Cell-Adapted Newcastle Disease Virus. Korean J. Poult. Sci. 39(2):113-120, 2012.

b) International conferences (including seminar):

Choi KS.Current situation of Newcastle disease in Asia. The solution to the current Newcastle disease in Malaysia. Veterinary Research Institute, Ipoh, Malaysia. 16 July, 2012 (Invited speaker).
Choi KS.Newcastle disease and vaccination. The solution to the current Newcastle disease in Malaysia. Veterinary Research Institute, Ipoh, Malaysia. 16 July, 2012(Invited speaker).
Choi KS.Current situation of Newcastle disease in Asia. Invited speaker. Hanoi University of Agriculture, Hanoi, Vietnam. 12 July, 2012 (Invited speaker).
Choi KS, Newcastle disease and avian infectious bronchitis. Indonesian veterinary drugs association (ASOHI), Jakarta, Indonesia. 27 Nov, 2012 (Invited speaker).

c) National onferences:

Choi KS, Kye SJ, Kim JY, Lee EK, Jeon WJ, Lee JH, Kwon JH, Park CK, Sung HW. Characterization of Newcastle disease virus at slaughterhouses in Korea. 2012 KSVS symposium on the role and future of veterinary science in the biomedical field. The Korean Society of Veterinary Science, 25 April, 2012, Chungbuk National University, Cheongju, Korea. Journal of Veterinary Sci. 52(1) (suppl):126, 2012.
Kim JY, Kye SJ, Choi KS, Jeon WJ, Yoon SS, Jeong W, Kwon JH, Park CK. Serological surveillance of Newcastle disease virus in wild birds in Korea. 2012 KSVS symposium on the role and future of veterinary science in the biomedical field. The Korean Society of Veterinary Science, 25 April, 2012, Chungbuk National University, Cheongju, Korea. Journal of Veterinary Sci. 52(1) (suppl):127, 2012.
Kim S, Choi KS, Kye SJ, Kim JY, Kwon JH, Park CK. Cloning and expression of the haemagglutinin-neuraminidase of avian paramyxovirus type 4 by recombinant baculovirus. 2012 KSVS symposium on the role and future of veterinary science in the biomedical field. The Korean Society of Veterinary Science, 25 April, 2012, Chungbuk National University, Cheongju, Korea. Journal of Veterinary Sci. 52(1) (suppl):129, 2012.
Kye SJ, Kim JY, Choi KS, Lee EK, Jeon WJ, Kwon JH, Lee JH, Park CK, Sung HW. Genetic characterization of Newcastle disease virus isolates from live bird markets in Korea. 2012 KSVS symposium on the role and future of veterinary science in the biomedical field. The Korean Society of Veterinary Science, 25 April, 2012, Chungbuk National University, Cheongju, Korea. Journal of Veterinary Sci. 52(1) (suppl):129, 2012.
Kye SJ, Kim JY, Choi KS, Lee EK, Jeon WJ, Batchuulon, Sodnomdarjaa R, Kwon JH, Park CK. Characterization of Newcastle disease virus isolated from the first outbreak case in Mongolia. 2012 KSVS symposium on the role and future of veterinary science in the biomedical field. The Korean Society of Veterinary Science, 25 April, 2012, Chungbuk National University, Cheongju, Korea. Journal of Veterinary Sci. 52(1) (suppl):130, 2012.
Kye SJ, Choi KS, Kim JY, Seul HJ, Kwon JH, Lee HS, Sung HW. Expression of a synthetic HN gene of avian paramyxovirus type 9 is inducible in baculovirus system. 2012 KSVS symposium on present and future of veterinary science. The Korean Society of Veterinary Science, 1-2 Nov, 2012, Palace hotel, Seoul, Korea. Journal of Veterinary Sci. 52(3) (suppl):254, 2012.
Kim JY, Kye SJ, Jeon WJ, Lee EK, Kwon JH, Lee HS, Choi KS. Protective effects of a live Newcastle disease virus NDRL0901 vaccine strain in chickens. 2012 KSVS symposium on present and future of veterinary science. The Korean Society of Veterinary Science, 1-2 Nov, 2012, Palace hotel, Seoul, Korea. Journal of Veterinary Sci. 52(3) (suppl):254, 2012.

ToR: To provide scientific and technical training for personnel from OIE Member Countries

To recommend the prescribed and alternative tests or vaccines as OIE Standards

15.Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries?

Yes No

a)Technical visits:...... 6

b)Seminars:...... 166

c)Hands-on training courses:...... 20

d)Internships (>1 month):...... 1

Type of technical training provided (a, b,c or d) / Country of origin of the expert(s) provided with training / No. participants from the corresponding country
a / Cambodia / 2
a / Malaysia / 4
b / Vietnam / 57
b / Malaysia / 100
b / Indonesia / 9
C / Cambodia / 2
C / Laos / 2
C / Malaysia / 2
C / Mongolia / 2
C / Myanmmar / 2
C / Nepal / 1
C / Philippines / 2
C / Singapore / 1
c / Thailand / 2
c / Vietnam / 2
C / Indonesia / 2
d / Philippines / 1

ToR:To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned

16.Does your laboratory have a Quality Management System certified according to an International Standard?

Yes No

17.Is your laboratory accredited by an international accreditation body?

Yes No

18.Does your laboratory maintain a “biorisk management system” for the pathogen and the disease concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2012, Chapter 1.1.3 orManual of Diagnostic Tests for Aquatic Animals 2012, Chapter 1.1.1)

Yes No

ToR:To organise and participate in scientific meetings on behalf of the OIE

19.Did your laboratory organise scientific meetings on behalf of the OIE?

Yes No

20.Did your laboratory participate in scientific meetings on behalf of the OIE?

Yes No

ToR:To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results

21.Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease?

Yes No

22.Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests?

Yes No

23.Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest?

Yes No

ToR:To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results.

24.Did your laboratory organiseor participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease?

Yes No

ToR:To place expert consultants at the disposal of the OIE

25.Did your laboratory place expert consultants at the disposal of the OIE?

Yes No

Kind of consultancy / Location / Subject (facultative )
Review of OIE Standards / Korea(Rep. Of) / Comments to Chapter 2.3.14 OIE Terrestrial Manual
Responding to specific technical queries from OIE / Korea(Rep. Of) / Comments to Chapter 2.3.14 OIE Terrestrial Manual
Reviewer of technical papers on diagnostic test procedures / Korea(Rep. Of) / Newcastle disease

Annual reports of OIE Reference Laboratories, 20121